Name: Name:Kinetin riboside
Brand: AABLOCKS
SKU: AA0034ZX
Rating: 90 (10 reviews)

Catalog No.: AA0034ZX

4338-47-0 | Kinetin riboside

Pack Size： 1g

Purity： ≥98%

in stock

$118.00 $82.00

Pack Size： 5g

Purity： ≥98%

in stock

$289.00 $202.00

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Technical Information

Catalog Number: AA0034ZX

Chemical Name: Kinetin riboside

CAS Number: 4338-47-0

Molecular Formula: C15H17N5O5

Molecular Weight: 347.3260

MDL Number: MFCD00037987

SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1ccco1

Properties

BP: 683.7°C at 760 mmHg

Form: Solid

MP: >129°C (dec.)

Storage: 2-8℃;

Complexity: 460

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 4

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 25

Hydrogen Bond Acceptor Count: 9

Hydrogen Bond Donor Count: 4

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0.2

Downstream Synthesis Route

617-89-0

342-69-8

4338-47-0

[1]Hamptonetal.[JournaloftheAmericanChemicalSociety,1956,vol.78,p.5695]

617-89-0

3510-73-4

4338-47-0

[1]Kissmann;Weiss[JournalofOrganicChemistry,1956,vol.21,p.1053]

98-01-1

58-61-7

4338-47-0

[1]Sattsangi,PremD.;Barrio,JorgeR.;Leonard,NelsonJ.[JournaloftheAmericanChemicalSociety,1980,vol.102,#2,p.770-774]

(2R,3R,4S,5R)-2-{6-(Benzotriazol-1-yl-furan-2-yl-methyl)-amino-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol

4338-47-0

[1]Afify,HananM.N.M.;Pedersen,ErikB.;Zahran,MagdyA.[JournalofHeterocyclicChemistry,2000,vol.37,#2,p.339-341]

Literature fold

Title: A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside.

Journal: Blood20120202

Title: Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line.

Journal: Nucleosides, nucleotides & nucleic acids20120101

Title: Simultaneous determination of different endogenetic plant growth regulators in common green seaweeds using dispersive liquid-liquid microextraction method.

Journal: Plant physiology and biochemistry : PPB20111101

Title: Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines.

Journal: Journal of cellular biochemistry20110801

Title: Anticancer activity of natural cytokinins: a structure-activity relationship study.

Journal: Phytochemistry20100801

Title: FKBP38 protects Bcl-2 from caspase-dependent degradation.

Journal: The Journal of biological chemistry20100326

Title: The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines.

Journal: Biochemical pharmacology20090401

Title: Inhibitory effect of kinetin riboside in human heptamoa, HepG2.

Journal: Molecular bioSystems20090101

Title: Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.

Journal: Journal of medicinal chemistry20080724

Title: Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

Journal: Bioorganic & medicinal chemistry20080401

Title: Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells.

Journal: Cancer letters20080308

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Rajabi M, et al. Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line. Nucleosides Nucleotides Nucleic Acids. 2012;31(6):474-81.

Title: Choi BH, et al. Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells. Cancer Lett. 2008 Mar 8;261(1):37-45.