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339-72-0,MFCD00064324
Catalog No.:AA00350I

339-72-0 | L-Cycloserine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
97%
in stock  
$6.00   $4.00
- +
5g
97%
in stock  
$116.00   $82.00
- +
25g
97%
in stock  
$318.00   $223.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00350I
Chemical Name:
L-Cycloserine
CAS Number:
339-72-0
Molecular Formula:
C3H6N2O2
Molecular Weight:
102.0919
MDL Number:
MFCD00064324
SMILES:
N[C@H]1CONC1=O
Properties
Properties
 
BP:
191.38°C (rough estimate)  
Form:
Solid  
MP:
147 °C  
Refractive Index:
1.5110 (estimate)  
Solubility:
H2O: soluble50mg/mg protein  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
92.9  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
-1.5  

Downstream Synthesis Route

[1]Smrtetal.[Experientia,1957,vol.13,p.291][CollectionofCzechoslovakChemicalCommunications,1957,vol.22,p.262,270]

[1]Plattneretal.[HelveticaChimicaActa,1957,vol.40,p.1531,1544]

[1]Tsuji,A.etal.[Heterocycles,1977,vol.8,p.153-157]

[1]Baldwin;Ng;Pratt[TetrahedronLetters,1987,vol.28,#37,p.4319-4320]

[1]Gordeev,MikhailF.;Luehr,GaryW.;Hui,HonC.;Gordon,EricM.;Patel,DineshV.[Tetrahedron,1998,vol.54,#52,p.15879-15890]

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

Journal: British journal of pharmacology 20111201

Title: NMDA receptors and fear extinction: implications for cognitive behavioral therapy.

Journal: Dialogues in clinical neuroscience 20111201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Journal: Molecular bioSystems 20100901

Title: Neuroimaging revolutionizes therapeutic approaches to chronic pain.

Journal: Molecular pain 20070101

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: L-cycloserine, an inhibitor of sphingolipid biosynthesis, inhibits HIV-1 cytopathic effects, replication, and infectivity.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19960201

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SDS
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Tags:339-72-0 Molecular Formula|339-72-0 MDL|339-72-0 SMILES|339-72-0 L-Cycloserine
Catalog No.: AA00350I
339-72-0,MFCD00064324
339-72-0 | L-Cycloserine
Pack Size： 100mg
Purity： 97%
in stock
$6.00 $4.00
Pack Size： 5g
Purity： 97%
in stock
$116.00 $82.00
Pack Size： 25g
Purity： 97%
in stock
$318.00 $223.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00350I
Chemical Name: L-Cycloserine
CAS Number: 339-72-0
Molecular Formula: C3H6N2O2
Molecular Weight: 102.0919
MDL Number: MFCD00064324
SMILES: N[C@H]1CONC1=O
Properties
BP: 191.38°C (rough estimate)  
Form: Solid  
MP: 147 °C  
Refractive Index: 1.5110 (estimate)  
Solubility: H2O: soluble50mg/mg protein  
Storage: Keep in dry area;-20 ℃;  
Complexity: 92.9  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 7  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
XLogP3: -1.5  
Downstream Synthesis Route
163682-35-7    339-72-0 

[1]Smrtetal.[Experientia,1957,vol.13,p.291][CollectionofCzechoslovakChemicalCommunications,1957,vol.22,p.262,270]

103758-42-5    339-72-0 

[1]Plattneretal.[HelveticaChimicaActa,1957,vol.40,p.1531,1544]

103-80-0    339-72-0    66444-64-2 

[1]Tsuji,A.etal.[Heterocycles,1977,vol.8,p.153-157]

339-72-0    115059-34-2 

[1]Baldwin;Ng;Pratt[TetrahedronLetters,1987,vol.28,#37,p.4319-4320]

82911-69-1    339-72-0    219829-15-9 

[1]Gordeev,MikhailF.;Luehr,GaryW.;Hui,HonC.;Gordon,EricM.;Patel,DineshV.[Tetrahedron,1998,vol.54,#52,p.15879-15890]

Literature fold

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry20121115

Title: The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

Journal: British journal of pharmacology20111201

Title: NMDA receptors and fear extinction: implications for cognitive behavioral therapy.

Journal: Dialogues in clinical neuroscience20111201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Journal: Molecular bioSystems20100901

Title: Neuroimaging revolutionizes therapeutic approaches to chronic pain.

Journal: Molecular pain20070101

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: L-cycloserine, an inhibitor of sphingolipid biosynthesis, inhibits HIV-1 cytopathic effects, replication, and infectivity.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association19960201

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