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4005-49-6,MFCD00037927
Catalog No.:AA00357T

4005-49-6 | N-(9H-Purin-6-yl)benzamide

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Purity
Availability
Price(USD)
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5g
98%
in stock  
$6.00   $4.00
- +
25g
98%
in stock  
$17.00   $12.00
- +
100g
98%
in stock  
$63.00   $44.00
- +
500g
98%
in stock  
$306.00   $214.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00357T
Chemical Name:
N-(9H-Purin-6-yl)benzamide
CAS Number:
4005-49-6
Molecular Formula:
C12H9N5O
Molecular Weight:
239.2328
MDL Number:
MFCD00037927
SMILES:
O=C(c1ccccc1)NC1=NC=NC2=NC=NC12
NSC Number:
98641
Properties
Properties
 
BP:
443.7°C at 760 mmHg  
Form:
Solid  
MP:
242-244 °C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
305  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.3  

Literature

Title: Synthesis and biological evaluation of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20120501

Title: Synthesis of 4,6-dideoxy-3-fluoro-2-keto-beta-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their antitumor activities.

Journal: Bioorganic chemistry 20100401

Title: Unsaturated dideoxy fluoro-ketopyranosyl nucleosides as new cytostatic agents: a convenient synthesis of 2,6-dideoxy-3-fluoro-4-keto-beta-D-glucopyranosyl analogues of uracil, 5-fluorouracil, thymine, N4-benzoyl cytosine and N6-benzoyl adenine.

Journal: European journal of medicinal chemistry 20091101

Title: One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

Journal: Journal of medicinal chemistry 20090723

Title: Unsaturated fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-4-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine and N(6)-benzoyl adenine.

Journal: European journal of medicinal chemistry 20080201

Title: Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

Journal: BMC biochemistry 20070101

Title: An enzymatic transglycosylation of purine bases.

Journal: Nucleosides, nucleotides & nucleic acids 20070101

Title: Short synthesis of octosyl nucleosides.

Journal: Organic letters 20060330

Title: 6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies.

Journal: Journal of enzyme inhibition and medicinal chemistry 20050801

Title: 2'-chloro-2',3'-dideoxy-3'-fluoro-d-ribonucleosides: synthesis, stereospecificity, some chemical transformations, and conformational analysis.

Journal: The Journal of organic chemistry 20030725

Title: Stereoselective synthesis of the beta-anomer of 4'-thionucleosides based on electrophilic glycosidation to 4-thiofuranoid glycals.

Journal: The Journal of organic chemistry 20020823

Title: Diastereocontrolled synthesis of dinucleoside phosphorothioates using a novel class of activators, dialkyl(cyanomethyl)ammonium tetrafluoroborates.

Journal: Journal of the American Chemical Society 20020508

Title: Synthesis and cytotoxicity of cyanoborane adducts of n6-benzoyladenine and 6-triphenylphosphonylpurine.

Journal: Metal-based drugs 20020101

Title: The adenine derivative of alpha-L-LNA (alpha-L-ribo configured locked nucleic acid): synthesis and high-affinity hybridization towards DNA, RNA, LNA and alpha-L-LNA complementary sequences.

Journal: Bioorganic & medicinal chemistry letters 20010409

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