13553-79-2,MFCD06198807
Catalog No.:AA0035HS

13553-79-2 | Rifamycin s

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$43.00   $30.00
- +
1g
>98.0%(HPLC)
in stock  
$84.00   $59.00
- +
5g
>98.0%(HPLC)
in stock  
$252.00   $176.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0035HS
Chemical Name:
Rifamycin s
CAS Number:
13553-79-2
Molecular Formula:
C37H45NO12
Molecular Weight:
695.7527
MDL Number:
MFCD06198807
SMILES:
COC1C=COC2(C)Oc3c(C2=O)c2C(=O)C=C(C(=O)c2c(c3C)O)NC(=O)C(=CC=CC(C(C(C(C(C(C1C)OC(=O)C)C)O)C)O)C)C
Properties
Properties
 
BP:
700.89°C (rough estimate)  
Form:
Solid  
MP:
179-181°C (dec.)  
Refractive Index:
1.6630 (estimate)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
1480  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
50  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
4.1  

Literature

Title: Detoxification of toxins by bacillithiol in Staphylococcus aureus.

Journal: Microbiology (Reading, England) 20120401

Title: Synthesis and structure-activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin.

Journal: Bioorganic & medicinal chemistry letters 20111015

Title: Direct generation of acyclic polypropionate stereopolyads via double diastereo- and enantioselective iridium-catalyzed crotylation of 1,3-diols: beyond stepwise carbonyl addition in polyketide construction.

Journal: Journal of the American Chemical Society 20110817

Title: Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica.

Journal: Antonie van Leeuwenhoek 20090201

Title: Preparation and in vitro anti-staphylococcal activity of novel 11-deoxy-11-hydroxyiminorifamycins.

Journal: Bioorganic & medicinal chemistry letters 20071015

Title: Hygrocins a and B, naphthoquinone macrolides from Streptomyces hygroscopicus.

Journal: Journal of natural products 20051201

Title: NMR spectroscopic analysis of new spiro-piperidylrifamycins.

Journal: Magnetic resonance in chemistry : MRC 20050401

Title: Expeditious asymmetric synthesis of a stereoheptad corresponding to the C(19)-C(27)-ansa chain of rifamycins: formal total synthesis of Rifamycin S.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20050107

Title: Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.

Journal: Biochemistry 20031021

Title: Solid state cultivation of Curvularia lunata for transformation of rifamycin B to S.

Journal: Indian journal of experimental biology 20020801

Title: Efficient strategy for the synthesis of stereopentad subunits of scytophycin, rifamycin S, and discodermolide.

Journal: Organic letters 20011213

Title: Oxabicyclo[3.2.1]octenes in organic synthesis--direct ring opening of oxabicyclo[3.2.1] systems employing silyl ketene acetals in concentrated solutions of lithium perchlorate-diethyl ether: application to the synthesis of the C(19)-C(27) fragment of rifamycin S.

Journal: Organic letters 20010208

Title: Structure-activity relationships in open ansa-chain rifamycin S derivatives as inhibitors of HIV-1 reverse transcriptase.

Journal: Farmaco (Societa chimica italiana : 1989) 19950901

Title: Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46.

Title: Kono Y. Oxygen Enhancement of bactericidal activity of rifamycin SV on Escherichia coli and aerobic oxidation of rifamycin SV to rifamycin S catalyzed by manganous ions: the role of superoxide. J Biochem. 1982 Jan;91(1):381-95.

Title: Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8.

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SDS
Tags:13553-79-2 Molecular Formula|13553-79-2 MDL|13553-79-2 SMILES|13553-79-2 Rifamycin s
Catalog No.: AA0035HS
13553-79-2,MFCD06198807
13553-79-2 | Rifamycin s
Pack Size: 100mg
Purity: 98%
in stock
$43.00 $30.00
Pack Size: 1g
Purity: >98.0%(HPLC)
in stock
$84.00 $59.00
Pack Size: 5g
Purity: >98.0%(HPLC)
in stock
$252.00 $176.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA0035HS
Chemical Name: Rifamycin s
CAS Number: 13553-79-2
Molecular Formula: C37H45NO12
Molecular Weight: 695.7527
MDL Number: MFCD06198807
SMILES: COC1C=COC2(C)Oc3c(C2=O)c2C(=O)C=C(C(=O)c2c(c3C)O)NC(=O)C(=CC=CC(C(C(C(C(C(C1C)OC(=O)C)C)O)C)O)C)C
Properties
BP: 700.89°C (rough estimate)  
Form: Solid  
MP: 179-181°C (dec.)  
Refractive Index: 1.6630 (estimate)  
Storage: 2-8℃;  
Complexity: 1480  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 9  
Defined Bond Stereocenter Count: 3  
Heavy Atom Count: 50  
Hydrogen Bond Acceptor Count: 12  
Hydrogen Bond Donor Count: 4  
Rotatable Bond Count: 3  
XLogP3: 4.1  
Literature fold

Title: Detoxification of toxins by bacillithiol in Staphylococcus aureus.

Journal: Microbiology (Reading, England)20120401

Title: Synthesis and structure-activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin.

Journal: Bioorganic & medicinal chemistry letters20111015

Title: Direct generation of acyclic polypropionate stereopolyads via double diastereo- and enantioselective iridium-catalyzed crotylation of 1,3-diols: beyond stepwise carbonyl addition in polyketide construction.

Journal: Journal of the American Chemical Society20110817

Title: Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica.

Journal: Antonie van Leeuwenhoek20090201

Title: Preparation and in vitro anti-staphylococcal activity of novel 11-deoxy-11-hydroxyiminorifamycins.

Journal: Bioorganic & medicinal chemistry letters20071015

Title: Hygrocins a and B, naphthoquinone macrolides from Streptomyces hygroscopicus.

Journal: Journal of natural products20051201

Title: NMR spectroscopic analysis of new spiro-piperidylrifamycins.

Journal: Magnetic resonance in chemistry : MRC20050401

Title: Expeditious asymmetric synthesis of a stereoheptad corresponding to the C(19)-C(27)-ansa chain of rifamycins: formal total synthesis of Rifamycin S.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20050107

Title: Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.

Journal: Biochemistry20031021

Title: Solid state cultivation of Curvularia lunata for transformation of rifamycin B to S.

Journal: Indian journal of experimental biology20020801

Title: Efficient strategy for the synthesis of stereopentad subunits of scytophycin, rifamycin S, and discodermolide.

Journal: Organic letters20011213

Title: Oxabicyclo[3.2.1]octenes in organic synthesis--direct ring opening of oxabicyclo[3.2.1] systems employing silyl ketene acetals in concentrated solutions of lithium perchlorate-diethyl ether: application to the synthesis of the C(19)-C(27) fragment of rifamycin S.

Journal: Organic letters20010208

Title: Structure-activity relationships in open ansa-chain rifamycin S derivatives as inhibitors of HIV-1 reverse transcriptase.

Journal: Farmaco (Societa chimica italiana : 1989)19950901

Title: Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46.

Title: Kono Y. Oxygen Enhancement of bactericidal activity of rifamycin SV on Escherichia coli and aerobic oxidation of rifamycin SV to rifamycin S catalyzed by manganous ions: the role of superoxide. J Biochem. 1982 Jan;91(1):381-95.

Title: Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8.

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