33005-95-7,MFCD00866089
Catalog No.:AA0035ME

33005-95-7 | Tiaprofenic acid

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Purity
Availability
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Quantity
  
5mg
≥98%
in stock  
$46.00   $32.00
- +
50mg
98%
in stock  
$56.00   $39.00
- +
100mg
98%
in stock  
$75.00   $53.00
- +
250mg
98%
in stock  
$112.00   $78.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0035ME
Chemical Name:
Tiaprofenic acid
CAS Number:
33005-95-7
Molecular Formula:
C14H12O3S
Molecular Weight:
260.3083
MDL Number:
MFCD00866089
SMILES:
OC(=O)C(c1ccc(s1)C(=O)c1ccccc1)C
Properties
Properties
 
BP:
450.3°C at 760 mmHg  
Form:
Solid  
MP:
96° (isopropyl ether)  
Refractive Index:
1.5050 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
323  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.3  

Downstream Synthesis Route

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

[2]Monti,Sandra;Encinas,Susana;Lahoz,Agustin;Marconi,Giancarlo;Sortino,Salvatore;Perez-Prieto,Julia;Miranda,MiguelA.[HelveticaChimicaActa,2001,vol.84,#9,p.2452-2466]

[3]Su,Tao;Ma,Jiani;Li,Ming-De;Guan,Xiangguo;Yu,Lihong;Phillips,DavidLee[JournalofPhysicalChemistryB,2013,vol.117,#3,p.811-824]

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

[2]Samadi,Abdelouahid;Martinez,LuisA.;Miranda,MiguelA.;Morera,IsabelM.[PhotochemistryandPhotobiology,2001,vol.73,#4,p.359-365]

[1]Singh;Jamali;Pasutto;Russell;Coutts;Drader[JournalofPharmaceuticalSciences,1986,vol.75,#5,p.439-442]

[2]CurrentPatentAssignee:DAICELCORPORATION-US8859757,2014,B2Locationinpatent:Page/Pagecolumn5-6

[3]Kucerova,Gabriela;Kalikova,Kveta;Tesarova,Eva[Chirality,2017,vol.29,#6,p.239-246]

[4]Onishi,Takafumi;Ueda,Takunori;Yoshida,Kenichi;Uosaki,Kosuke;Ando,Hiroyuki;Hamasaki,Ryota;Ohnishi,Atsushi[Chirality,2022,vol.34,#7,p.925-940]

6066-82-6    33005-95-7   
Tiaprofensaeure-hydroxysuccinimidester 

[1]Unterhalt;Baudner;Degenhardt[Pharmazie,1995,vol.50,#8,p.571-572]

Literature

Title: Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes.

Journal: Chemico-biological interactions 20171001

Title: Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

Journal: Toxicology letters 20150105

Title: Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts.

Journal: Journal of photochemistry and photobiology. B, Biology 20120502

Title: Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20120215

Title: Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20120101

Title: Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study.

Journal: PloS one 20120101

Title: Risk of hospitalization for upper gastrointestinal adverse events associated with nonsteroidal anti-inflammatory drugs: a nationwide case-crossover study in Taiwan.

Journal: Pharmacoepidemiology and drug safety 20110701

Title: Single dose oral analgesics for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20110101

Title: Non-steroidal anti-inflammatory drug (NSAID) related inhibition of aldosterone glucuronidation and arterial dysfunction in patients with rheumatoid arthritis: a cross-sectional clinical study.

Journal: BMJ open 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: The effect of terpenes on percutaneous absorption of tiaprofenic acid gel.

Journal: Archives of pharmacal research 20101101

Title: Hemorrhagic cystitis: A challenge to the urologist.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20100101

Title: Enhancement of antinociception by coadministration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis.

Journal: BMC musculoskeletal disorders 20100101

Title: Contact dermatitis due to topical drugs.

Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20091001

Title: Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.

Journal: British journal of clinical pharmacology 20090901

Title: Photodegradation mechanism of nonsteroidal anti-inflammatory drugs containing thiophene moieties: suprofen and tiaprofenic acid.

Journal: The journal of physical chemistry. B 20090813

Title: Systematic review of the management of canine osteoarthritis.

Journal: The Veterinary record 20090404

Title: An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model.

Journal: BMC veterinary research 20090101

Title: Single dose oral tiaprofenic acid for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20090101

Title: Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial.

Journal: Arthritis research & therapy 20090101

Title: The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery.

Journal: Yonsei medical journal 20081031

Title: Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of tiaprofenic acid in nonstandard HPLC organic solvents.

Journal: Chirality 20080801

Title: The antiplatelet effect of six non-steroidal anti-inflammatory drugs and their pharmacodynamic interaction with aspirin in healthy volunteers.

Journal: The American journal of cardiology 20080401

Title: Cholesterol-diaryl ketone stereoisomeric dyads as models for 'clean' type I and type II photooxygenation mechanisms.

Journal: Organic & biomolecular chemistry 20080307

Title: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis.

Journal: Arthritis research & therapy 20080101

Title: Acute NSAID-related transmural duodenitis and extensive duodenal ulceration.

Journal: Clinical therapeutics 20071101

Title: Effectiveness of conservative treatments for the lumbosacral radicular syndrome: a systematic review.

Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20070701

Title: Activity and potential role of licofelone in the management of osteoarthritis.

Journal: Clinical interventions in aging 20070301

Title: Upper gastrointestinal complications associated with NSAIDs in children.

Journal: Therapie 20070101

Title: The pK(a) Distribution of Drugs: Application to Drug Discovery.

Journal: Perspectives in medicinal chemistry 20070101

Title: Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060901

Title: In vitro interactions of captopril with NSAID's.

Journal: Pakistan journal of pharmaceutical sciences 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Patterns of non steroidal anti-inflammatory drug use in ambulatory care].

Journal: Therapie 20060101

Title: 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

Journal: Journal of medicinal chemistry 20050630

Title: The modulation of intra-articular inflammation, cartilage matrix and bone loss in mono-articular arthritis induced by heat-killed Mycobacterium tuberculosis.

Journal: Inflammopharmacology 20050101

Title: Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery.

Journal: Head & face medicine 20050101

Title: Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population.

Journal: BMC medicine 20050101

Title: Risk of breast cancer among users of aspirin and other anti-inflammatory drugs.

Journal: British journal of cancer 20040802

Title: Evaluation of balhimycin as a chiral selector for enantioresolution by capillary electrophoresis.

Journal: Electrophoresis 20040801

Title: Vehicle effects on in vitro release of tiaprofenic acid from different topical formulations.

Journal: Farmaco (Societa chimica italiana : 1989) 20040701

Title: Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases.

Journal: Biomedical chromatography : BMC 20030701

Title: Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study.

Journal: British journal of cancer 20030602

Title: Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules.

Journal: Contact dermatitis 20030301

Title: Indomethacin-induced morphologic changes in the rat urinary bladder epithelium.

Journal: Urology 20030101

Title: The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes.

Journal: BMC pharmacology 20030101

Title: The role of the Australian Adverse Drug Reactions Advisory Committee (ADRAC) in monitoring drug safety.

Journal: Toxicology 20021227

Title: Fixed drug eruption due to tiaprofenic acid.

Journal: The Journal of dermatological treatment 20021201

Title: [Photocontact dermatitis due to ketoprofen and photosensitization to tetrachlorosalicylanide and to Fenticlor(R)].

Journal: Annales de dermatologie et de venereologie 20021001

Title: Use of the photo-micronucleus assay in Chinese hamster V79 cells to study photochemical genotoxicity.

Journal: Mutation research 20020826

Title: Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020801

Title: Do NSAIDs affect the progression of osteoarthritis?

Journal: Inflammation 20020601

Title: [Cross-reaction potentials of ketoprofen].

Journal: Orvosi hetilap 20020512

Title: Experimental study on phototoxicity and the photosensitization potential of ketoprofen, suprofen, tiaprofenic acid and benzophenone and the photocross-reactivity in guinea pigs.

Journal: Photodermatology, photoimmunology & photomedicine 20020401

Title: [Results of a French nationwide survey of cutaneous side effects of ketoprofen gel reported between September 1996 and August 2000].

Journal: Therapie 20020101

Title: [Tuberculous osteitis of the malar bone].

Journal: Medecine tropicale : revue du Corps de sante colonial 20020101

Title: Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

Journal: Chemical research in toxicology 20011101

Title: Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.

Journal: Immunopharmacology and immunotoxicology 20011101

Title: The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis.

Journal: Acta orthopaedica Scandinavica 20011001

Title: [Photoaggravated contact allergy and contact photoallergy caused by ketoprofen: 19 cases].

Journal: Annales de dermatologie et de venereologie 20011001

Title: Photocontact dermatitis to ketoprofen.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010901

Title: In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010601

Title: Mechanism of lipid peroxidation photosensitized by tiaprofenic acid: product studies using linoleic acid and 1,4-cyclohexadienes as model substrates.

Journal: Photochemistry and photobiology 20010401

Title: Eotaxin expression and eosinophil infiltrate in the liver of patients with drug-induced liver disease.

Journal: Journal of hepatology 20010401

Title: [New technologies in laparoscopic surgery].

Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20010301

Title: Effects of some nonsteroidal anti-inflammatory drugs on articular cartilage of rats in an experimental model of osteoarthritis.

Journal: Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 20010301

Title: Five cases of photocontact dermatitis due to topical ketoprofen: photopatch testing and cross-reaction study.

Journal: Photodermatology, photoimmunology & photomedicine 20010201

Title: Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations.

Journal: BMC clinical pharmacology 20010101

Title: Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries.

Journal: Electrophoresis 20010101

Title: Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Journal: Journal of analytical toxicology 20010101

Title: Diclofenac induced hepatitis. 3 cases with features of autoimmune chronic active hepatitis.

Journal: Digestive diseases and sciences 19930401

Title: Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.

Journal: Acta anaesthesiologica Scandinavica 19930401

Title: Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

Journal: The Journal of pharmacology and experimental therapeutics 19930101

Title: Hepatotoxicity to several nonsteroidal anti-inflammatory drugs with diclofenac induced histological changes.

Journal: Clinical rheumatology 19920301

Title: G L Plosker, et al. Tiaprofenic Acid. A Reappraisal of Its Pharmacological Properties and Use in the Management of Rheumatic Diseases. Drugs. 1995 Dec;50(6):1050-75.

Title: L J Benincosa, et al. Tiaprofenic Acid Inhibits the Renal Reabsorption of Sulfate in Rats. Prostaglandins Leukot Essent Fatty Acids. 1993 Jul;49(1):503-8.

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SDS
Tags:33005-95-7 Molecular Formula|33005-95-7 MDL|33005-95-7 SMILES|33005-95-7 Tiaprofenic acid
Catalog No.: AA0035ME
33005-95-7,MFCD00866089
33005-95-7 | Tiaprofenic acid
Pack Size: 5mg
Purity: ≥98%
in stock
$46.00 $32.00
Pack Size: 50mg
Purity: 98%
in stock
$56.00 $39.00
Pack Size: 100mg
Purity: 98%
in stock
$75.00 $53.00
Pack Size: 250mg
Purity: 98%
in stock
$112.00 $78.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0035ME
Chemical Name: Tiaprofenic acid
CAS Number: 33005-95-7
Molecular Formula: C14H12O3S
Molecular Weight: 260.3083
MDL Number: MFCD00866089
SMILES: OC(=O)C(c1ccc(s1)C(=O)c1ccccc1)C
Properties
BP: 450.3°C at 760 mmHg  
Form: Solid  
MP: 96° (isopropyl ether)  
Refractive Index: 1.5050 (estimate)  
Storage: Keep in dry area;2-8℃;  
Complexity: 323  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 18  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 1  
XLogP3: 3.3  
Downstream Synthesis Route
67-56-1    33005-95-7    6933-26-2    5912-44-7    143379-91-3    143381-62-8 

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

33005-95-7    6933-26-2 

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

[2]Monti,Sandra;Encinas,Susana;Lahoz,Agustin;Marconi,Giancarlo;Sortino,Salvatore;Perez-Prieto,Julia;Miranda,MiguelA.[HelveticaChimicaActa,2001,vol.84,#9,p.2452-2466]

[3]Su,Tao;Ma,Jiani;Li,Ming-De;Guan,Xiangguo;Yu,Lihong;Phillips,DavidLee[JournalofPhysicalChemistryB,2013,vol.117,#3,p.811-824]

33005-95-7    6933-26-2    5912-44-7    143379-91-3 

[1]Bosca;Miranda;Vargas[JournalofPharmaceuticalSciences,1992,vol.81,#2,p.181-182]

[2]Samadi,Abdelouahid;Martinez,LuisA.;Miranda,MiguelA.;Morera,IsabelM.[PhotochemistryandPhotobiology,2001,vol.73,#4,p.359-365]

33005-95-7    103667-49-8    103667-50-1 

[1]Singh;Jamali;Pasutto;Russell;Coutts;Drader[JournalofPharmaceuticalSciences,1986,vol.75,#5,p.439-442]

[2]CurrentPatentAssignee:DAICELCORPORATION-US8859757,2014,B2Locationinpatent:Page/Pagecolumn5-6

[3]Kucerova,Gabriela;Kalikova,Kveta;Tesarova,Eva[Chirality,2017,vol.29,#6,p.239-246]

[4]Onishi,Takafumi;Ueda,Takunori;Yoshida,Kenichi;Uosaki,Kosuke;Ando,Hiroyuki;Hamasaki,Ryota;Ohnishi,Atsushi[Chirality,2022,vol.34,#7,p.925-940]

6066-82-6    33005-95-7   
Tiaprofensaeure-hydroxysuccinimidester 

[1]Unterhalt;Baudner;Degenhardt[Pharmazie,1995,vol.50,#8,p.571-572]

Literature fold

Title: Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes.

Journal: Chemico-biological interactions20171001

Title: Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

Journal: Toxicology letters20150105

Title: Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts.

Journal: Journal of photochemistry and photobiology. B, Biology20120502

Title: Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease.

Journal: The Cochrane database of systematic reviews20120215

Title: Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.)20120101

Title: Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study.

Journal: PloS one20120101

Title: Risk of hospitalization for upper gastrointestinal adverse events associated with nonsteroidal anti-inflammatory drugs: a nationwide case-crossover study in Taiwan.

Journal: Pharmacoepidemiology and drug safety20110701

Title: Single dose oral analgesics for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews20110101

Title: Non-steroidal anti-inflammatory drug (NSAID) related inhibition of aldosterone glucuronidation and arterial dysfunction in patients with rheumatoid arthritis: a cross-sectional clinical study.

Journal: BMJ open20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: The effect of terpenes on percutaneous absorption of tiaprofenic acid gel.

Journal: Archives of pharmacal research20101101

Title: Hemorrhagic cystitis: A challenge to the urologist.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India20100101

Title: Enhancement of antinociception by coadministration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis.

Journal: BMC musculoskeletal disorders20100101

Title: Contact dermatitis due to topical drugs.

Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia20091001

Title: Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.

Journal: British journal of clinical pharmacology20090901

Title: Photodegradation mechanism of nonsteroidal anti-inflammatory drugs containing thiophene moieties: suprofen and tiaprofenic acid.

Journal: The journal of physical chemistry. B20090813

Title: Systematic review of the management of canine osteoarthritis.

Journal: The Veterinary record20090404

Title: An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model.

Journal: BMC veterinary research20090101

Title: Single dose oral tiaprofenic acid for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews20090101

Title: Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial.

Journal: Arthritis research & therapy20090101

Title: The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery.

Journal: Yonsei medical journal20081031

Title: Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of tiaprofenic acid in nonstandard HPLC organic solvents.

Journal: Chirality20080801

Title: The antiplatelet effect of six non-steroidal anti-inflammatory drugs and their pharmacodynamic interaction with aspirin in healthy volunteers.

Journal: The American journal of cardiology20080401

Title: Cholesterol-diaryl ketone stereoisomeric dyads as models for 'clean' type I and type II photooxygenation mechanisms.

Journal: Organic & biomolecular chemistry20080307

Title: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis.

Journal: Arthritis research & therapy20080101

Title: Acute NSAID-related transmural duodenitis and extensive duodenal ulceration.

Journal: Clinical therapeutics20071101

Title: Effectiveness of conservative treatments for the lumbosacral radicular syndrome: a systematic review.

Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society20070701

Title: Activity and potential role of licofelone in the management of osteoarthritis.

Journal: Clinical interventions in aging20070301

Title: Upper gastrointestinal complications associated with NSAIDs in children.

Journal: Therapie20070101

Title: The pK(a) Distribution of Drugs: Application to Drug Discovery.

Journal: Perspectives in medicinal chemistry20070101

Title: Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20060901

Title: In vitro interactions of captopril with NSAID's.

Journal: Pakistan journal of pharmaceutical sciences20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: [Patterns of non steroidal anti-inflammatory drug use in ambulatory care].

Journal: Therapie20060101

Title: 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

Journal: Journal of medicinal chemistry20050630

Title: The modulation of intra-articular inflammation, cartilage matrix and bone loss in mono-articular arthritis induced by heat-killed Mycobacterium tuberculosis.

Journal: Inflammopharmacology20050101

Title: Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery.

Journal: Head & face medicine20050101

Title: Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population.

Journal: BMC medicine20050101

Title: Risk of breast cancer among users of aspirin and other anti-inflammatory drugs.

Journal: British journal of cancer20040802

Title: Evaluation of balhimycin as a chiral selector for enantioresolution by capillary electrophoresis.

Journal: Electrophoresis20040801

Title: Vehicle effects on in vitro release of tiaprofenic acid from different topical formulations.

Journal: Farmaco (Societa chimica italiana : 1989)20040701

Title: Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases.

Journal: Biomedical chromatography : BMC20030701

Title: Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study.

Journal: British journal of cancer20030602

Title: Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules.

Journal: Contact dermatitis20030301

Title: Indomethacin-induced morphologic changes in the rat urinary bladder epithelium.

Journal: Urology20030101

Title: The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes.

Journal: BMC pharmacology20030101

Title: The role of the Australian Adverse Drug Reactions Advisory Committee (ADRAC) in monitoring drug safety.

Journal: Toxicology20021227

Title: Fixed drug eruption due to tiaprofenic acid.

Journal: The Journal of dermatological treatment20021201

Title: [Photocontact dermatitis due to ketoprofen and photosensitization to tetrachlorosalicylanide and to Fenticlor(R)].

Journal: Annales de dermatologie et de venereologie20021001

Title: Use of the photo-micronucleus assay in Chinese hamster V79 cells to study photochemical genotoxicity.

Journal: Mutation research20020826

Title: Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20020801

Title: Do NSAIDs affect the progression of osteoarthritis?

Journal: Inflammation20020601

Title: [Cross-reaction potentials of ketoprofen].

Journal: Orvosi hetilap20020512

Title: Experimental study on phototoxicity and the photosensitization potential of ketoprofen, suprofen, tiaprofenic acid and benzophenone and the photocross-reactivity in guinea pigs.

Journal: Photodermatology, photoimmunology & photomedicine20020401

Title: [Results of a French nationwide survey of cutaneous side effects of ketoprofen gel reported between September 1996 and August 2000].

Journal: Therapie20020101

Title: [Tuberculous osteitis of the malar bone].

Journal: Medecine tropicale : revue du Corps de sante colonial20020101

Title: Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

Journal: Chemical research in toxicology20011101

Title: Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.

Journal: Immunopharmacology and immunotoxicology20011101

Title: The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis.

Journal: Acta orthopaedica Scandinavica20011001

Title: [Photoaggravated contact allergy and contact photoallergy caused by ketoprofen: 19 cases].

Journal: Annales de dermatologie et de venereologie20011001

Title: Photocontact dermatitis to ketoprofen.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society20010901

Title: In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie20010601

Title: Mechanism of lipid peroxidation photosensitized by tiaprofenic acid: product studies using linoleic acid and 1,4-cyclohexadienes as model substrates.

Journal: Photochemistry and photobiology20010401

Title: Eotaxin expression and eosinophil infiltrate in the liver of patients with drug-induced liver disease.

Journal: Journal of hepatology20010401

Title: [New technologies in laparoscopic surgery].

Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen20010301

Title: Effects of some nonsteroidal anti-inflammatory drugs on articular cartilage of rats in an experimental model of osteoarthritis.

Journal: Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie20010301

Title: Five cases of photocontact dermatitis due to topical ketoprofen: photopatch testing and cross-reaction study.

Journal: Photodermatology, photoimmunology & photomedicine20010201

Title: Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations.

Journal: BMC clinical pharmacology20010101

Title: Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries.

Journal: Electrophoresis20010101

Title: Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Journal: Journal of analytical toxicology20010101

Title: Diclofenac induced hepatitis. 3 cases with features of autoimmune chronic active hepatitis.

Journal: Digestive diseases and sciences19930401

Title: Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.

Journal: Acta anaesthesiologica Scandinavica19930401

Title: Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

Journal: The Journal of pharmacology and experimental therapeutics19930101

Title: Hepatotoxicity to several nonsteroidal anti-inflammatory drugs with diclofenac induced histological changes.

Journal: Clinical rheumatology19920301

Title: G L Plosker, et al. Tiaprofenic Acid. A Reappraisal of Its Pharmacological Properties and Use in the Management of Rheumatic Diseases. Drugs. 1995 Dec;50(6):1050-75.

Title: L J Benincosa, et al. Tiaprofenic Acid Inhibits the Renal Reabsorption of Sulfate in Rats. Prostaglandins Leukot Essent Fatty Acids. 1993 Jul;49(1):503-8.

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