[1]Patent:US6369106,2002,B1
[1]Patent:WO2015/181551,2015,A1.Locationinpatent:Page/Pagecolumn35
[2]AngewandteChemie-InternationalEdition,2008,vol.47,p.2244-2247
[3]Patent:WO2014/11624,2014,A2.Locationinpatent:Paragraph00139;00140
[4]Patent:WO2015/148880,2015,A1.Locationinpatent:Paragraph0024;0025
[5]Patent:WO2016/185200,2016,A1.Locationinpatent:Page/Pagecolumn30;31
[1]CurrentPatentAssignee:XPDHOLDINGS-WO2014/11624,2014,A2Locationinpatent:Paragraph00143;00144
Title: N-acetylcysteine amide, a promising antidote for acetaminophen toxicity.
Journal: Toxicology letters 20160122
Title: Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury.
Journal: The Journal of biological chemistry 20150605
Title: N-acetylcysteine amide protects against methamphetamine-induced tissue damage in CD-1 mice.
Journal: Human & experimental toxicology 20120901
Title: Characterizing N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) binding for lead poisoning treatment.
Journal: Journal of colloid and interface science 20120401
Title: Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans.
Journal: PLoS biology 20120301
Title: Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications.
Journal: TheScientificWorldJournal 20120101
Title: Protective effects of N-acetylcysteine amide (NACA) on gentamicin-induced apoptosis in LLC-PK1 cells.
Journal: Renal failure 20120101
Title: Glutathione homeostasis and functions: potential targets for medical interventions.
Journal: Journal of amino acids 20120101
Title: Free radical scavenger properties of α-mangostin: thermodynamics and kinetics of HAT and RAF mechanisms.
Journal: The journal of physical chemistry. B 20111103
Title: Effectiveness of sulfur-containing antioxidants in delaying skeletal muscle fatigue.
Journal: Medicine and science in sports and exercise 20110601
Title: Directing dopaminergic fiber growth along a preformed molecular pathway from embryonic ventral mesencephalon transplants in the rat brain.
Journal: Journal of neuroscience research 20110501
Title: N-acetylcysteine amide (NACA) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation.
Journal: The American journal of pathology 20110501
Title: Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells.
Journal: Free radical biology & medicine 20110401
Title: In vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide.
Journal: Free radical biology & medicine 20110315
Title: Comparative evaluation of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) on glutamate and lead-induced toxicity in CD-1 mice.
Journal: Toxicology letters 20110225
Title: Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling.
Journal: Respiratory research 20110101
Title: In vitro acute exposure to DEHP affects oocyte meiotic maturation, energy and oxidative stress parameters in a large animal model.
Journal: PloS one 20110101
Title: The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism.
Journal: PloS one 20110101
Title: Effects of N-acetyl-cysteine and N-acetyl-cysteine-amide supplementation on in vitro matured porcine oocytes.
Journal: Reproduction in domestic animals = Zuchthygiene 20101001
Title: HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: potential role of the thiol antioxidant N-acetylcysteine amide.
Journal: Free radical biology & medicine 20100515
Title: N-acetylcysteine amide protects renal proximal tubular epithelial cells against iohexol-induced apoptosis by blocking p38 MAPK and iNOS signaling.
Journal: American journal of nephrology 20100101
Title: Attenuation of pulmonary inflammation after exposure to blast overpressure by N-acetylcysteine amide.
Journal: Shock (Augusta, Ga.) 20090901
Title: N-acetylcysteineamide (NACA) prevents inflammation and oxidative stress in animals exposed to diesel engine exhaust.
Journal: Toxicology letters 20090622
Title: N-Acetylcysteine amide protects against methamphetamine-induced oxidative stress and neurotoxicity in immortalized human brain endothelial cells.
Journal: Brain research 20090612
Title: N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes.
Journal: BMC pharmacology 20090101
Title: Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB.
Journal: Arthritis research & therapy 20090101
Title: Effects of N-acetylcysteine amide (NACA), a thiol antioxidant on radiation-induced cytotoxicity in Chinese hamster ovary cells.
Journal: Life sciences 20080523
Title: Antioxidant and free radical scavenging properties of N-acetylcysteine amide (NACA) and comparison with N-acetylcysteine (NAC).
Journal: Free radical research 20080401
Title: N-acetylcysteine amide (AD4) attenuates oxidative stress in beta-thalassemia blood cells.
Journal: Biochimica et biophysica acta 20080201
Title: Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress.
Journal: Neoplasia (New York, N.Y.) 20080201
Title: A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kappaB and hypoxia-inducible factor-1alpha.
Journal: Experimental & molecular medicine 20071231
Title: [N-acetylcysteine improves lysosomal function and enhances the degradation of photoreceptor outer segments in cultured RPE cells].
Journal: Klinische Monatsblatter fur Augenheilkunde 20070701
Title: Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes.
Journal: Diabetes research and clinical practice 20070501
Title: Role of N-acetylcysteine in the management of COPD.
Journal: International journal of chronic obstructive pulmonary disease 20061201
Title: Potentiation of lead-induced cell death in PC12 cells by glutamate: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant.
Journal: Toxicology and applied pharmacology 20061015
Title: A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells.
Journal: Experimental neurology 20060901
Title: Separation and quantification of N-acetyl-l-cysteine and N-acetyl-cysteine-amide by HPLC with fluorescence detection.
Journal: Biomedical chromatography : BMC 20060501
Title: Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity.
Journal: Brain research 20060119
Title: Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12.
Journal: Brain research 20050921
Title: Is brain dehydroepiandrosterone synthesis modulated by free radicals in mice?
Journal: Neuroscience letters 20050329
Title: N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress.
Journal: Free radical biology & medicine 20050101
Title: Analysis of gene expression in MOG-induced experimental autoimmune encephalomyelitis after treatment with a novel brain-penetrating antioxidant.
Journal: Journal of molecular neuroscience : MN 20050101
Title: A novel brain-targeted antioxidant (AD4) attenuates haloperidol-induced abnormal movement in rats: implications for tardive dyskinesia.
Journal: Clinical neuropharmacology 20050101
Title: A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis.
Journal: Journal of neurochemistry 20040601
Title: Shi R, et al. N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes. BMC Pharmacol. 2009 Apr 15;9:7.
Title: Pandya JD, et al. N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI. Exp Neurol. 2014 Jul;257:106-13.
Title: Zhang X, et al. N-Acetylcysteine amide protects against methamphetamine-induced oxidative stress and neurotoxicity in immortalized human brain endothelial cells. Brain Res. 2009 Jun 12;1275:87-95.