Title: Dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD.
Journal: Bioorganic & medicinal chemistry letters 20120215
Title: SAR of a series of 5,6-dihydro-(9H)-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-alpha]pyridines as potent inhibitors of human eosinophil phosphodiesterase.
Journal: Journal of medicinal chemistry 20070125
Title: Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.
Journal: Bioorganic & medicinal chemistry letters 20060701
Title: Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity.
Journal: Structure (London, England : 1993) 20030701
Title: Crystal structure of 5-t-butoxycarbonyl-1-benzoyl-2-pyrrolidinone, an intermediate in the synthesis of (-)-rolipram.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020701
Title: Novel selective PDE4 inhibitors. 3. In vivo antiinflammatory activity of a new series of N-substituted cis-tetra- and cis-hexahydrophthalazinones.
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Title: Novel selective PDE4 inhibitors. 2. Synthesis and structure-activity relationships of 4-aryl-substituted cis-tetra- and cis-hexahydrophthalazinones.
Journal: Journal of medicinal chemistry 20010802
Title: Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct 18;45(4):944.