Catalog No.:AA003741

57688-34-3 | 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine, HCl

Name: Name:4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine, HCl
Brand: AABLOCKS
SKU: AA003741
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

100mg

98%

in stock

$14.00 $10.00

- +

250mg

98%

in stock

$29.00 $21.00

- +

98%

in stock

$99.00 $69.00

- +

98%

in stock

$477.00 $334.00

- +

10g

98%

in stock

$809.00 $567.00

- +

25g

98%

in stock

$1,607.00 $1,125.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA003741

Chemical Name:

4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine, HCl

CAS Number:

57688-34-3

Molecular Formula:

C13H10F3N

Molecular Weight:

237.2204

MDL Number:

MFCD03424687

SMILES:

Nc1ccc(cc1)c1ccc(cc1)C(F)(F)F

Properties

BP:

303.1°C at 760 mmHg

Form:

Solid

Storage:

Keep in dry area;2-8℃;

Computed Properties

Complexity:

236

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

Downstream Synthesis Route

128796-39-4

106-40-1

57688-34-3

[1]Contreras-Celedn,ClaudiaA.;Mendoza-Rayo,Daro;Rincn-Medina,JosA.;Chacn-Garca,Luis[BeilsteinJournalofOrganicChemistry,2014,vol.10,p.2821-2826]

[2]Parrish,CynthiaA.;Adams,NicholasD.;Auger,KurtR.;Burgess,JoelleL.;Carson,JeffreyD.;Chaudhari,AmitaM.;Copeland,RobertA.;Diamond,MelodyA.;Donatelli,CarlaA.;Duffy,KevinJ.;Faucette,LeoF.;Finer,JeffreyT.;Huffman,WilliamF.;Hugger,ErinD.;Jackson,JeffreyR.;Knight,StevenD.;Luo,Lusong;Moore,MichaelL.;Newlander,KenA.;Ridgers,LanceH.;Sakowicz,Roman;Shaw,AntonyN.;Sung,Chiu-MeiM.;Sutton,David;Wood,KennethW.;Zhang,Shu-Yun;Zimmerman,MichaelN.;Dhanak,Dashyant[JournalofMedicinalChemistry,2007,vol.50,#20,p.4939-4952]

[3]CurrentPatentAssignee:GLAXOSMITHKLINEPLC;CYTOKINETICSINC-WO2006/20358,2006,A2Locationinpatent:Page/Pagecolumn35

[4]CurrentPatentAssignee:CYTOKINETICSINC-US2007/142460,2007,A1Locationinpatent:Page/Pagecolumn15

[5]CurrentPatentAssignee:CYTOKINETICSINC-US2007/259951,2007,A1Locationinpatent:Page/Pagecolumn16

[6]CurrentPatentAssignee:PFIZERINC-US2012/165343,2012,A1Locationinpatent:Page/Pagecolumn41

[7]Ren;McClelland[CanadianJournalofChemistry,1998,vol.76,#1,p.78-84]

[8]Locationinpatent:experimentalpartNakayama,Hikaru;Nishida,Jun-Ichi;Takada,Noriyuki;Sato,Hiroyasu;Yamashita,Yoshiro[ChemistryofMaterials,2012,vol.24,#4,p.671-676]

[9]Liu,Jingru;Ma,Ruxin;Bi,Fangchao;Zhang,Fa;Hu,Chaoyu;Venter,Henrietta;Semple,SusanJ.;Ma,Shutao[BioorganicandMedicinalChemistryLetters,2018,vol.28,#10,p.1825-1831]

[10]CurrentPatentAssignee:BIOMARINPHARMACEUTICALINC-WO2019/133770,2019,A2Locationinpatent:Paragraph00514;00515;00516;001173;001174;001175

[11]CurrentPatentAssignee:BIOMARINPHARMACEUTICALINC;BIOMARINPHARMINC-WO2020/257487,2020,A1Locationinpatent:Paragraph00472;00473;001131;001132

57688-34-3

207287-84-1

[1]Ren;McClelland[CanadianJournalofChemistry,1998,vol.76,#1,p.78-84]

80245-34-7

57688-34-3

[1]Glende,Carsten;Klein,Markus;Schmitt,Heimo;Erdinger,Lothar;Boche,Gernot[MutationResearch-GeneticToxicologyandEnvironmentalMutagenesis,2002,vol.515,#1-2,p.15-38]

[2]Chen,Tao;Li,Wen-Qin;Liu,Zheng;Jiang,Wen;Liu,Tian;Yang,Qing;Zhu,Xiao-Lei;Yang,Guang-Fu[JournalofAgriculturalandFoodChemistry,2021,vol.69,#40,p.12039-12047]

ammoniumthiocyanate

57688-34-3

N-4'-(trifluoromethyl)-4-biphenylylthiourea

[1]CurrentPatentAssignee:GLAXOSMITHKLINEPLC;CYTOKINETICSINC-WO2006/20358,2006,A2Locationinpatent:Page/Pagecolumn47-48

358-23-6

57688-34-3

1,1,1-trifluoro-N-4'-(trifluoromethyl)-4-biphenylylmethanesulfonamide

[1]CurrentPatentAssignee:CYTOKINETICSINC-US2007/259951,2007,A1Locationinpatent:Page/Pagecolumn17

Literature

Title: Novel ATP-competitive kinesin spindle protein inhibitors.

Journal: Journal of medicinal chemistry 20071004

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