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5108-96-3,MFCD00012720
Catalog No.:AA0037AB

5108-96-3 | 1-Pyrrolidinecarbodithioic acid ammonium salt

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100mg
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$6.00   $4.00
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5g
98%
in stock  
$16.00   $11.00
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25g
95%
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$32.00   $23.00
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100g
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500g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0037AB
Chemical Name:
1-Pyrrolidinecarbodithioic acid ammonium salt
CAS Number:
5108-96-3
Molecular Formula:
C5H12N2S2
Molecular Weight:
164.2922
MDL Number:
MFCD00012720
SMILES:
[S-]C(=S)N1CCCC1.[NH4+]
Properties
Properties
 
BP:
329.4°C at 760 mmHg  
Form:
Solid  
MP:
153-155 °C(lit.)  
Refractive Index:
1.5300 (estimate)  
Solubility:
190g/l  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
91.1  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  

Literature

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Title: Involvement of 15-lipoxygenase in the inflammatory arthritis.

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Title: Foxp3 expression in A549 cells is regulated by Toll-like receptor 4 through nuclear factor-κB.

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Title: Sphingosine-1-phosphate is a mediator of TNF-α action on the Na+/K+ ATPase in HepG2 cells.

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Title: Chronic inhibition of nuclear factor kappa B attenuates aldosterone/salt-induced renal injury.

Journal: Life sciences 20120420

Title: Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-κB/bFGF signaling.

Journal: World journal of gastroenterology 20120414

Title: High glucose-induced expression of inflammatory cytokines and reactive oxygen species in cultured astrocytes.

Journal: Neuroscience 20120127

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Title: Suppression of NF-κB reduces myocardial no-reflow.

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Title: Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells.

Journal: Experimental & molecular medicine 20111231

Title: Down-regulation of matrix metalloproteinase-9 by pyrrolidine dithiocarbamate prevented retinal ganglion cell death after transection of optic nerve in rats.

Journal: Current eye research 20111101

Title: Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway.

Journal: International journal of molecular medicine 20111001

Title: An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-κB-independent mechanism.

Journal: Cellular signalling 20110901

Title: Inhibition of NF-κB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation.

Journal: Journal of neuro-oncology 20110801

Title: 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.

Journal: Prostaglandins & other lipid mediators 20110801

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Journal: The Journal of biological chemistry 20110715

Title: Programmed hypertension in rats treated with a NF-κB inhibitor during nephrogenesis: renal mechanisms.

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Title: Nitric oxide in enteric nervous system mediated the inhibitory effect of vasopressin on the contraction of circular muscle strips from colon in male rats.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110301

Title: Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.

Journal: Bioorganic & medicinal chemistry letters 20110201

Title: Nuclear factor kappa B pathway down-regulates aquaporin 5 in the nasal mucosa of rats with allergic rhinitis.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110101

Title: Inhibition of nuclear factor κB regresses cardiac hypertrophy by modulating the expression of extracellular matrix and adhesion molecules.

Journal: Free radical biology & medicine 20110101

Title: The influence of passive stretch and NF-κB inhibitors on the morphology of dystrophic muscle fibers.

Journal: Anatomical record (Hoboken, N.J. : 2007) 20110101

Title: Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

Title: Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.

Journal: PloS one 20110101

Title: Nuclear factor-κB inhibitors alleviate nivalenol-induced cytotoxicity in HL60 cells.

Journal: Environmental toxicology and pharmacology 20110101

Title: Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage.

Journal: Journal of neuroinflammation 20110101

Title: Characterization of polysaccharide from Astragalus radix as the macrophage stimulator.

Journal: Cellular immunology 20110101

Title: TNFα-induced necroptosis and autophagy via supression of the p38-NF-κB survival pathway in L929 cells.

Journal: Journal of pharmacological sciences 20110101

Title: Expressions of lymphotactin and its receptor, XCR, in Lewis rats with experimental autoimmune anterior uveitis.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20101201

Title: Shock wave induces chronic renal lesion through activation of the nuclear factor kappa B signaling pathway.

Journal: World journal of urology 20101001

Title: 5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB.

Journal: Immunology and cell biology 20101001

Title: C-reactive protein triggers inflammatory responses partly via TLR4/IRF3/NF-κB signaling pathway in rat vascular smooth muscle cells.

Journal: Life sciences 20100911

Title: Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts.

Journal: Journal of muscle research and cell motility 20100901

Title: [Study about cardiomyocyte apoptosis in myocardial ischemic-reperfusion injury of rats and NF-κB p65, iNOS expression].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20100901

Title: Effects of NF-kappaB inhibitor on titanium particulate-induced inflammation in a murine model.

Journal: The Journal of surgical research 20100801

Title: Involvement of NF-kappaB activation in the apoptosis induced by extracellular adenosine in human hepatocellular carcinoma HepG2 cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801

Title: Inhibition of immune-mediated concanavalin a-induced liver damage by free-radical scavengers.

Journal: Digestive diseases and sciences 20100201

Title: Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion.

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Title: SLC/CCR7 stimulates the proliferation of BMDCs by the pNF-kappaB p65 pathway.

Journal: Anatomical record (Hoboken, N.J. : 2007) 20100101

Title: Hypoxia activates heparanase expression in an NF-kappaB dependent manner.

Journal: Oncology reports 20100101

Title: Amyloid-β induces cyclooxygenase-2 and PGE2 release in human astrocytes in NF-κ B dependent manner.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells.

Journal: Scandinavian journal of immunology 20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway.

Journal: Archives of biochemistry and biophysics 20090901

Title: Increased expression and activity of MMP-9 in C-reactive protein- induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801

Title: Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway.

Journal: Bioscience trends 20090801

Title: Toll-like receptor 9 agonists promote IL-8 and TGF-beta1 production via activation of nuclear factor kappaB in PC-3 cells.

Journal: Cancer genetics and cytogenetics 20090715

Title: PDTC enables type I TRAIL signaling in type II follicular lymphoma cells.

Journal: Leukemia research 20090601

Title: Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.

Journal: Lung cancer (Amsterdam, Netherlands) 20090601

Title: Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.

Journal: Cardiovascular research 20090601

Title: Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells.

Journal: Molecular nutrition & food research 20090601

Title: The effects of PDTC on interleukin-1beta-induced nitric oxide production in chondrocytes.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090601

Title: Protective effects of asiatic acid against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in hepatocytes and kupffer cells co-cultured system via redox-regulated leukotriene C4 synthase expression pathway.

Journal: European journal of pharmacology 20090128

Title: Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats.

Journal: Pain 20090101

Title: Cocaine induces cell death and activates the transcription nuclear factor kappa-B in PC12 cells.

Journal: Molecular brain 20090101

Title: Anti-angiogenic actions of pyrrolidine dithiocarbamate, a nuclear factor kappa B inhibitor.

Journal: Angiogenesis 20090101

Title: Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin.

Journal: PloS one 20090101

Title: Protection of capsaicin against hypoxia-reoxygenation-induced apoptosis of rat hippocampal neurons.

Journal: Canadian journal of physiology and pharmacology 20081101

Title: Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells.

Journal: American journal of physiology. Renal physiology 20081001

Title: Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081001

Title: [Research of signaling pathway of vascular endothelial growth factor regulating by hepatitis B virus X protein].

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Title: Inhibitory effect of zinc on hypoxic HIF-1 activation in astrocytes.

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Title: The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats.

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Title: Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080501

Title: TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-kappa B pathways.

Journal: Molecular immunology 20080301

Title: The role of metals in modulating metalloprotease activity in the AD brain.

Journal: European biophysics journal : EBJ 20080301

Title: Relationship between carbachol hyperstimulation-induced pancreatic intracellular trypsinogen and NF-kappa B activation in rats in vitro.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080201

Title: HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study.

Journal: BMC infectious diseases 20080101

Title: NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.

Journal: Journal of biochemical and molecular toxicology 20080101

Title: Albumin induces interleukin-6 release from primary human proximal tubule epithelial cells.

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Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20071201

Title: Nuclear factor-kappaB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis.

Journal: The Journal of biological chemistry 20071116

Title: Role of Rel A and IkappaB of nuclear factor kappaB in the release of interleukin-8 by cyclic mechanical strain in human alveolar type II epithelial cells A549.

Journal: Respirology (Carlton, Vic.) 20071101

Title: Potential contribution of nuclear factor-kappaB to cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits.

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Title: Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.

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Title: Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: YC-1 attenuates LPS-induced proinflammatory responses and activation of nuclear factor-kappaB in microglia.

Journal: British journal of pharmacology 20070601

Title: Relaxin-induced matrix metalloproteinase-9 expression is associated with activation of the NF-kappaB pathway in human THP-1 cells.

Journal: Journal of leukocyte biology 20070501

Title: Endogenously generated hydrogen peroxide induces apoptosis via mitochondrial damage independent of NF-kappaB and p53 activation in bovine embryos.

Journal: Theriogenology 20070415

Title: Role of nuclear factor kappa B (NF-kappaB) in oxidative stress-induced defective dopamine D1 receptor signaling in the renal proximal tubules of Sprague-Dawley rats.

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Journal: Life sciences 20070102

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Title: UVB-induced IL-18 production in human keratinocyte cell line NCTC 2544 through NF-kappaB activation.

Journal: Cytokine 20070101

Title: Tumor necrosis factor alpha alters Na+-K+ ATPase activity in rat cardiac myocytes: involvement of NF-kappaB, AP-1 and PGE2.

Journal: Life sciences 20061214

Title: [Signaling pathways in expression of inducible nitric oxide synthase induced by high mobility group box 1 in rat alveolar macrophages].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20061201

Title: Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism.

Journal: Journal of cellular biochemistry 20061101

Title: [Expression of inducible nitric oxide synthase was regulated by activating nuclear factor kappaB in mouse macrophages stimulated with ureaplasma urealyticum lipid-associated membrane proteins].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20061001

Title: Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake.

Journal: Chemistry & biology 20060901

Title: Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20060801

Title: P53 status influences regulation of HSPs and ribosomal proteins by PDTC and radiation.

Journal: Biochemical and biophysical research communications 20060505

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.

Journal: Cellular signalling 20060301

Title: Deregulation of cyclin-dependent kinase 2 activity correlates with UVC-induced apoptosis in Chinese hamster ovary cells.

Journal: Journal of cellular biochemistry 20060301

Title: Insulin-like growth factor-1 prevents Abeta[25-35]/(H2O2)- induced apoptosis in lymphocytes by reciprocal NF-kappaB activation and p53 inhibition via PI3K-dependent pathway.

Journal: Growth factors (Chur, Switzerland) 20060301

Title: Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice.

Journal: Experimental neurology 20060301

Title: Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages.

Journal: Molecular immunology 20060201

Title: Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.

Journal: Leukemia research 20060201

Title: Roles of Ras and extracellular signal-regulated kinase-dependent IkappaBalpha degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells.

Journal: International immunopharmacology 20060201

Title: Changes in the human peritoneal mesothelial cells during aging.

Journal: Kidney international 20060101

Title: Survivin contributes to the anti-apoptotic activities of transforming growth factor alpha in mouse blastocysts through phosphatidylinositol 3'-kinase pathway.

Journal: Biology of reproduction 20051201

Title: [Inhibition of rat corneal neovascularization by inhibitor of nuclear factor-kappaB].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051201

Title: Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro.

Journal: American journal of physiology. Cell physiology 20051101

Title: NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.

Journal: Life sciences 20051014

Title: Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation.

Journal: The European journal of neuroscience 20051001

Title: Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.

Journal: Free radical biology & medicine 20050915

Title: Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.

Journal: Journal of toxicology and environmental health. Part A 20050901

Title: Lovastatin reduces nuclear factor kappaB activation induced by C-reactive protein in human vascular endothelial cells.

Journal: Biological & pharmaceutical bulletin 20050901

Title: HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signaling.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050801

Title: Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.

Journal: Journal of neurochemistry 20050801

Title: Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells.

Journal: Kidney international 20050801

Title: FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB.

Journal: The Journal of biological chemistry 20050729

Title: Involvement of the NMDA receptor, NO-cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma.

Journal: Human psychopharmacology 20050701

Title: Expression of CX3C chemokine, fractalkine, and its receptor CX3CR1 in experimental autoimmune anterior uveitis.

Journal: Molecular vision 20050701

Title: Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.

Journal: Brain research 20050628

Title: Signaling pathways involved in tumor necrosis factor alpha-induced upregulation of the taurine transporter in Caco-2 cells.

Journal: FEBS letters 20050606

Title: [Inhibitory effect of daunorubicin enhanced by PDTC on drug-resistant leukemic cells in vitro].

Journal: Zhongguo shi yan xue ye xue za zhi 20050601

Title: Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.

Journal: Cancer immunology, immunotherapy : CII 20050501

Title: Inhibiton of NF-kappaB activation during ischemia reduces hepatic ischemia/reperfusion injury in rats.

Journal: The Journal of toxicological sciences 20050501

Title: [Role of nitric oxide-nuclear factor kappaB signal pathway in functional expression of T lymphocytes from asthmatic patients].

Journal: Zhonghua nei ke za zhi 20050501

Title: PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer.

Journal: Neoplasia (New York, N.Y.) 20050301

Title: Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-kappaB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on human hepatoma cell.

Journal: Biochemical pharmacology 20050215

Title: [Homocysteine induces macrophage inflammatory protein-1alpha expression by activating NF-kappaB in THP-1 monocytes].

Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20050201

Title: Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.

Journal: Neuropharmacology 20050101

Title: Effect of 17beta-estradiol on tumor necrosis factor-alpha-induced cytotoxicity in the human peripheral T lymphocytes.

Journal: The Journal of endocrinology 20050101

Title: Antiandrogen-like actions of an antioxidant on survivin, Bcl-2 and PSA in human prostate cancer cells.

Journal: Cancer detection and prevention 20050101

Title: Effects of a redox-active agent on lymphocyte activation and early gene expression patterns.

Journal: Free radical biology & medicine 20041115

Title: NF-kappaB activation is required for the development of cardiac hypertrophy in vivo.

Journal: American journal of physiology. Heart and circulatory physiology 20041001

Title: Hyporesponsiveness in alloreactive T-cells by NF-kappaB inhibitor-treated dendritic cells: resistance to calcineurin inhibition.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901

Title: YC-1-induced cyclooxygenase-2 expression is mediated by cGMP-dependent activations of Ras, phosphoinositide-3-OH-kinase, Akt, and nuclear factor-kappaB in human pulmonary epithelial cells.

Journal: Molecular pharmacology 20040901

Title: Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.

Journal: Journal of neuroscience research 20040701

Title: Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040701

Title: Inhibition of nuclear factor-kappa B prevents staphylococcal enterotoxin A-induced fever.

Journal: Molecular and cellular biochemistry 20040701

Title: A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630

Title: Proteasome inhibitors up-regulate haem oxygenase-1 gene expression: requirement of p38 MAPK (mitogen-activated protein kinase) activation but not of NF-kappaB (nuclear factor kappaB) inhibition.

Journal: The Biochemical journal 20040501

Title: The signal transduction pathway that mediates the effect of interleukin-1 beta on the Na+-K+-ATPase in LLC-PK1 cells.

Journal: Pflugers Archiv : European journal of physiology 20040501

Title: Increase of cyclooxygenase-2 expression by interleukin 15 in rheumatoid synoviocytes.

Journal: The Journal of rheumatology 20040501

Title: A new antimalarial quassinoid from Simaba orinocensis.

Journal: Journal of natural products 20040501

Title: TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040401

Title: Hyperhomocysteinemia activates NF-kappaB and inducible nitric oxide synthase in the kidney.

Journal: Kidney international 20040401

Title: [Effect of protein kinase C-nuclear factor-kappa B signal transduction pathway on proliferation and expression of vascular endothelial growth factor in human pulmonary artery smooth muscle cells].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20040401

Title: PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase.

Journal: Journal of cellular physiology 20040201

Title: Laminar shear stress up-regulates inducible nitric oxide synthase in the endothelium.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040201

Title: Endotoxin releases a precursor to vasodilation from large veins in an NF-kappaB-dependent manner.

Journal: The Journal of surgical research 20040101

Title: NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines.

Journal: Annals of the New York Academy of Sciences 20031201

Title: NF-kappaB in critical diseases: a bad guy?

Journal: Intensive care medicine 20031101

Title: Protection of mitochondrial perturbation by human T-lymphotropic virus type 1 tax through induction of Bcl-xL expression.

Journal: The Journal of laboratory and clinical medicine 20031101

Title: Decrease in activity of smooth muscle L-type Ca2+ channels and its reversal by NF-kappaB inhibitors in Crohn's colitis model.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030901

Title: Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

Title: Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides.

Journal: Free radical research 20030901

Title: Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway.

Journal: The Biochemical journal 20030715

Title: IGF-1 potentiation of IL-4-induced CD23/Fc(epsilon)RII expression in human B cells.

Journal: Molecules and cells 20030630

Title: Dykellic acid inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting nuclear factor kappa B transcriptional activity.

Journal: Cancer research 20030615

Title: Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030601

Title: Activation of selective transcription factors and cytokines by water-soluble extract from Lentinus lepideus.

Journal: Experimental biology and medicine (Maywood, N.J.) 20030601

Title: Production of nitric oxide and tumor necrosis factor-alpha by Smilacis rhizoma in mouse peritoneal macrophages.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030601

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Title: Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1.

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Title: Antioxidant amplifies antibiotic protection in the cecal ligation and puncture model of microbial sepsis through interleukin-10 production.

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Title: Glucocorticoids aggravate hyperoxia-induced lung injury through decreased nuclear factor-kappa B activity.

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Journal: Investigative ophthalmology & visual science 20030101

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Journal: Biological chemistry 20030101

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Journal: Annals of plastic surgery 20021201

Title: Constitutively active NFkappa B is required for the survival of S-type neuroblastoma.

Journal: The Journal of biological chemistry 20021101

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Journal: Laboratory investigation; a journal of technical methods and pathology 20021001

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Journal: Oncogene 20020829

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Journal: Inflammation 20020801

Title: NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020701

Title: Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2.

Journal: The Journal of clinical endocrinology and metabolism 20020701

Title: IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020601

Title: Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells.

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Journal: Cardiovascular research 20020401

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Journal: The Biochemical journal 20020115

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Journal: BMC cardiovascular disorders 20020101

Title: Testosterone is a potential augmentor of antioxidant-induced apoptosis in human prostate cancer cells.

Journal: Cancer detection and prevention 20020101

Title: Inhibition of nuclear factor kappaB induces apoptosis following treatment with tumor necrosis factor alpha and an antioxidant in human prostate cancer cells.

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Title: Nuclear factor kappa B is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells.

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Title: Regulation of MARCKS and MARCKS-related protein expression in BV-2 microglial cells in response to lipopolysaccharide.

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Journal: Journal of molecular and cellular cardiology 20010201

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