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3306-62-5,MFCD00007932
Catalog No.:AA0037KW

3306-62-5 | 2-Aminobenzenesulfonamide

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  • Technical Information
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Technical Information
Catalog Number:
AA0037KW
Chemical Name:
2-Aminobenzenesulfonamide
CAS Number:
3306-62-5
Molecular Formula:
C6H8N2O2S
Molecular Weight:
172.2049
MDL Number:
MFCD00007932
SMILES:
Nc1ccccc1S(=O)(=O)N
NSC Number:
36945
Properties
Properties
 
BP:
392.7±44.0°C at 760 mmHg  
Form:
Solid  
MP:
155-157 °C(lit.)  
Refractive Index:
1.6490 (estimate)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
219  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
0.2  

Literature

Title: Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.

Journal: Journal of medicinal chemistry 20120412

Title: Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.

Journal: Bioorganic & medicinal chemistry 20120215

Title: Label-free detection of protein binding with multisine SPR microchips.

Journal: Lab on a chip 20111221

Title: Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.

Journal: Bioorganic & medicinal chemistry 20110815

Title: A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.

Journal: Bioorganic & medicinal chemistry 20110201

Title: Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.

Journal: Bioorganic & medicinal chemistry letters 20110115

Title: 3-(6-Bromo-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: 3-(6-Fluoro-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.

Journal: Journal of medicinal chemistry 20100527

Title: 3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20100515

Title: Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.

Journal: Journal of medicinal chemistry 20100311

Title: Gene expression signature-based screening identifies new broadly effective influenza a antivirals.

Journal: PloS one 20100101

Title: Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.

Journal: Bioorganic & medicinal chemistry 20090701

Title: Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.

Journal: Journal of medicinal chemistry 20090514

Title: Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.

Journal: Journal of medicinal chemistry 20090423

Title: A novel class of allosteric modulators of AMPA/Kainate receptors.

Journal: Bioorganic & medicinal chemistry letters 20090215

Title: Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.

Journal: Bioorganic & medicinal chemistry 20090201

Title: Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety.

Journal: Bioorganic & medicinal chemistry 20080315

Title: Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.

Journal: Bioorganic & medicinal chemistry 20071201

Title: Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.

Journal: Journal of medicinal chemistry 20070125

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.

Journal: Bioorganic & medicinal chemistry letters 20060415

Title: QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach.

Journal: Bioorganic & medicinal chemistry letters 20060401

Title: Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.

Journal: Journal of medicinal chemistry 20060323

Title: Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.

Journal: Journal of medicinal chemistry 20051201

Title: Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20050901

Title: Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

Journal: Bioorganic & medicinal chemistry letters 20050215

Title: Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20050215

Title: Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.

Journal: Bioorganic & medicinal chemistry letters 20040716

Title: Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20040621

Title: Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20030324

Title: Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

Journal: Journal of medicinal chemistry 20020328

Title: Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.

Journal: Bioorganic & medicinal chemistry letters 20010226

Title: Vullo D, et al. Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1005-9.

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Tags:3306-62-5 Molecular Formula|3306-62-5 MDL|3306-62-5 SMILES|3306-62-5 2-Aminobenzenesulfonamide