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2389-60-8,MFCD00062271
Catalog No.:AA003827

2389-60-8 | Z-Lys(Boc)-OH

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$16.00   $11.00
- +
5g
98%
in stock  
$31.00   $22.00
- +
10g
98%
in stock  
$37.00   $26.00
- +
25g
98%
in stock  
$91.00   $64.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003827
Chemical Name:
Z-Lys(Boc)-OH
CAS Number:
2389-60-8
Molecular Formula:
C19H28N2O6
Molecular Weight:
380.4354
MDL Number:
MFCD00062271
SMILES:
OC(=O)[C@@H](NC(=O)OCc1ccccc1)CCCCNC(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
483  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
12  
XLogP3:
2.8  

Upstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1982,vol.104,#16,p.4446-4450

[2]Patent:EP1426366,2004,A1,.Locationinpatent:Page28-29

[1]Patent:WO2007/127173,2007,A2,.Locationinpatent:Page/Pagecolumn34

[2]Patent:US2009/156627,2009,A1,.Locationinpatent:Page/Pagecolumn25

[3]Patent:WO2009/18549,2009,A1,.Locationinpatent:Page/Pagecolumn49

[4]BioorganicandMedicinalChemistryLetters,2007,vol.17,#2,p.305-308

[5]JournaloftheChemicalSociety-PerkinTransactions1,1998,#2,p.359-365

[6]BioorganicandMedicinalChemistryLetters,2010,vol.20,#10,p.3150-3154

[1]Patent:WO2008/14811,2008,A1,.Locationinpatent:Page/Pagecolumn17-18

[1]JournaloftheAmericanChemicalSociety,1982,vol.104,#16,p.4446-4450

[2]BulletinoftheChemicalSocietyofJapan,1964,vol.37,p.1471-1477

[3]Patent:WO2018/51197,2018,A1,.Locationinpatent:Paragraph0088;0174

[1]JournaloftheAmericanChemicalSociety,1965,vol.87,p.99-104

[2]JournaloftheAmericanChemicalSociety,1968,vol.90,#20,p.5598-5603

[3]JournalofOrganicChemistry,1971,vol.36,p.3022-3026

[4]ChemischeBerichte,1964,vol.97,p.3305-3311

[5]JustusLiebigsAnnalenderChemie,1964,vol.674,p.218-225

Downstream Synthesis Route

[1]IndianJournalofChemistry,1974,vol.12,p.458-463

[1]Cindro,Nikola;Horvat,Gordan;Rinkovec,Tamara;Riva,Davide;Speranza,Giovanna;Tomišić,Vladislav;Vidović,Nikolina[OrganicLetters,2020]

[2]Cortes-Clerget,Margery;Spink,SummerE.;Gallagher,GregoryP.;Chaisemartin,Laurent;Filaire,Edith;Berthon,Jean-Yves;Lipshutz,BruceH.[GreenChemistry,2019,vol.21,#10,p.2610-2614]

[3]Hoffmann,K.etal.[JournaloftheAmericanChemicalSociety,1964,vol.86,p.4991-4999]

[1]JournaloftheAmericanChemicalSociety,2000,vol.122,p.9046-9047

[2]JournaloftheAmericanChemicalSociety,1978,vol.100,p.3585-3590

[3]BioorganicandMedicinalChemistry,1996,vol.4,p.1185-1196

[4]JustusLiebigsAnnalenderChemie,1964,vol.674,p.218-225

[5]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.1866-1870

[6]OrganicandBiomolecularChemistry,2010,vol.8,p.1315-1321

[1]SyntheticCommunications,1981,vol.11,p.303-314

[2]TetrahedronLetters,2003,vol.44,p.4981-4984

[3]OrganicandBiomolecularChemistry,2011,vol.9,p.2597-2601

[4]TetrahedronLetters,2019,vol.60,p.948-952

[5]ChemischeBerichte,1972,vol.105,p.740-742

[6]JournaloftheAmericanChemicalSociety,1965,vol.87,p.99-104

[7]ChemicalandPharmaceuticalBulletin,1981,vol.29,p.2592-2597

[8]JournalofMedicinalChemistry,2007,vol.50,p.550-565

[1]HelveticaChimicaActa,1963,vol.46,p.1637-1669

[2]ChemischeBerichte,1964,vol.97,p.1819-1828

[3]JustusLiebigsAnnalenderChemie,1964,vol.674,p.218-225

[4]JournalofOrganicChemistry,2003,vol.68,p.1314-1318

Literature

Title: Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies.

Journal: Bioorganic & medicinal chemistry letters 20050301

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