Home Amines 203787-91-1
203787-91-1,MFCD00952954
Catalog No.:AA00383Y

203787-91-1 | Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt

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50mg
98%
in stock  
$8.00   $5.00
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100mg
98%
in stock  
$12.00   $8.00
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250mg
98%
in stock  
$15.00   $10.00
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1g
97%
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$26.00   $18.00
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5g
98%
in stock  
$56.00   $39.00
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10g
98%
in stock  
$85.00   $59.00
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25g
98%
in stock  
$148.00   $103.00
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100g
97%
in stock  
$433.00   $303.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00383Y
Chemical Name:
Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt
CAS Number:
203787-91-1
Molecular Formula:
C15H20NNaO4
Molecular Weight:
301.3134
MDL Number:
MFCD00952954
SMILES:
[O-]C(=O)CCCCCCCNC(=O)c1ccccc1O.[Na+]
Properties
Computed Properties
 
Complexity:
312  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  

Literature

Title: Phase I clinical study to select a novel oral formulation for ibandronate containing the excipient sodium N-[8-(2-hydroxybenzoyl) amino] caprylate (SNAC).

Journal: Die Pharmazie 20120301

Title: Orally administered glucagon-like peptide-1 affects glucose homeostasis following an oral glucose tolerance test in healthy male subjects.

Journal: Clinical pharmacology and therapeutics 20091201

Title: Peri- and postnatal developmental toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley rats.

Journal: International journal of toxicology 20090101

Title: Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats.

Journal: International journal of toxicology 20090101

Title: Mechanistic understanding of oral drug absorption enhancement of cromolyn sodium by an amino acid derivative.

Journal: Pharmaceutical research 20080101

Title: Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis.

Journal: Journal of the American Chemical Society 20070221

Title: Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis.

Journal: Journal of the American Chemical Society 20050706

Title: Investigation of the enhancing mechanism of sodium N-[8-(2-hydroxybenzoyl)amino]caprylate effect on the intestinal permeability of polar molecules utilizing a voltage clamp method.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601

Title: Oral delivery of insulin with the eligen technology: mechanistic studies.

Journal: Current drug delivery 20050401

Title: [Effect of casein and protamine on the enzymatic degradation and the orally hypoglycemic action of insulin].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20041001

Title: A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20040401

Title: Gastrointestinal absorption enhancement of insulin by administration of enteric microspheres and SNAC to rats.

Journal: Journal of microencapsulation 20040201

Title: [Studies on gastrointestinal absorption enhancement effect and mechanism of sodium N-[8-(2-hydroxybenzyl)amino] caprylate to insulin solution].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031201

Title: Pathway of oral absorption of heparin with sodium N-[8-(2-hydroxybenzoyl)amino] caprylate.

Journal: Pharmaceutical research 20020801

Title: Riley MGI, et, al. Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats. Int J Toxicol. Jul-Aug 2009; 28(4):278-93.

Title: Twarog C, et, al. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C 10). Pharmaceutics. 2019 Feb 13; 11(2):78.

Title: Li Y, et, al. Impact of Sodium N--(2-Hydroxybenzoyl)amino-caprylate on Intestinal Permeability for Notoginsenoside R1 and Salvianolic Acids in Caco-2 Cells Transport and Rat Pharmacokinetics. Molecules. 2018 Nov 16; 23(11):2990.

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Tags:203787-91-1 Molecular Formula|203787-91-1 MDL|203787-91-1 SMILES|203787-91-1 Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt