Title: Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature.
Journal: Archives of toxicology 20170401
Title: Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.
Journal: Oncotarget 20170227
Title: The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals.
Journal: Mutation research 20161115
Title: OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
Journal: International journal of cancer 20161101
Title: MCM5 as a target of BET inhibitors in thyroid cancer cells.
Journal: Endocrine-related cancer 20160401
Title: Resveratrol Represses Pokemon Expression in Human Glioma Cells.
Journal: Molecular neurobiology 20160301
Title: PARP Inhibitors Sensitize Ewing Sarcoma Cells to Temozolomide-Induced Apoptosis via the Mitochondrial Pathway.
Journal: Molecular cancer therapeutics 20151201
Title: Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Journal: Oncotarget 20151020
Title: Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.
Journal: Journal of medicinal chemistry 20150910
Title: Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20150901
Title: Dopamine induces growth inhibition and vascular normalization through reprogramming M2-polarized macrophages in rat C6 glioma.
Journal: Toxicology and applied pharmacology 20150715
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
Journal: The Lancet. Oncology 20140901
Title: The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140701
Title: Silencing of Hsp27 and Hsp72 in glioma cells as a tool for programmed cell death induction upon temozolomide and quercetin treatment.
Journal: Toxicology and applied pharmacology 20131215
Title: Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.
Journal: BMC cancer 20130101
Title: A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
Journal: Investigational new drugs 20121201
Title: Treatment of elderly patients with glioblastoma: from clinical evidence to molecular highlights.
Journal: Cancer treatment reviews 20121201
Title: Long-term survival in cerebellar glioblastoma multiforme. Case report.
Journal: Journal of neurosurgical sciences 20121201
Title: MGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution study.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Phase II trial of radiosurgery to magnetic resonance spectroscopy-defined high-risk tumor volumes in patients with glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: efficacy and toxicity.
Journal: Clinical neurology and neurosurgery 20121101
Title: Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Olea europaea leaf extract alters microRNA expression in human glioblastoma cells.
Journal: Journal of cancer research and clinical oncology 20121101
Title: Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma.
Journal: Journal of neuro-oncology 20121101
Title: Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas.
Journal: Journal of neuro-oncology 20121101
Title: Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas.
Journal: Academic radiology 20121101
Title: Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents.
Journal: Journal of neurochemistry 20121101
Title: Chemosensitized radiosurgery for recurrent brain metastases.
Journal: Journal of neuro-oncology 20121101
Title: Chemotherapy in low-grade gliomas.
Journal: Current opinion in oncology 20121101
Title: Glioblastoma cell line-derived spheres in serum‑containing medium versus serum-free medium: a comparison of cancer stem cell properties.
Journal: International journal of oncology 20121101
Title: A single centre study of the treatment of relapsed primary central nervous system lymphoma (PCNSL) with single agent temozolomide.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121101
Title: Celecoxib desensitization: continued temozolomide/celecoxib chemotherapy after a celecoxib-induced hypersensitivity reaction.
Journal: Anti-cancer drugs 20121101
Title: F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
Journal: Cancer gene therapy 20121101
Title: A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.
Journal: Pharmacogenetics and genomics 20121101
Title: Phase I-II study of radiopeptide 177Lu-octreotate in combination with capecitabine and temozolomide in advanced low-grade neuroendocrine tumors.
Journal: Cancer biotherapy & radiopharmaceuticals 20121101
Title: Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma.
Journal: Cancer letters 20121028
Title: Enhanced stability and activity of temozolomide in primary glioblastoma multiforme cells with cucurbit[n]uril.
Journal: Chemical communications (Cambridge, England) 20121011
Title: Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.
Journal: British journal of cancer 20121009
Title: NK cell immunotherapy for high-risk neuroblastoma relapse after haploidentical HSCT.
Journal: Pediatric blood & cancer 20121001
Title: Invasive Mycoleptodiscus fungal cellulitis and myositis.
Journal: Medical mycology 20121001
Title: Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
Journal: Cancer 20121001
Title: A study of clinico-pathological parameters and O⁶-methylguanine DNA methyltransferase (MGMT) promoter methylation status in the prognostication of gliosarcoma.
Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20121001
Title: Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme.
Journal: Immunology and cell biology 20121001
Title: Crystal engineering of stable temozolomide cocrystals.
Journal: Chemistry, an Asian journal 20121001
Title: Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.
Journal: The Journal of investigative dermatology 20121001
Title: Glioblastoma multiforme imaging: the role of nuclear medicine.
Journal: Current radiopharmaceuticals 20121001
Title: Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival.
Journal: Journal of cancer research and clinical oncology 20121001
Title: Neuroendocrine tumor disease: an evolving landscape.
Journal: Endocrine-related cancer 20121001
Title: Steroid-sparing effects of angiotensin-II inhibitors in glioblastoma patients.
Journal: European journal of neurology 20121001
Title: Chemotherapy and target therapy in the management of adult high- grade gliomas.
Journal: Current cancer drug targets 20121001
Title: A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma.
Journal: Journal of neuro-oncology 20121001
Title: Phase II study of single-agent bevacizumab in Japanese patients with recurrent malignant glioma.
Journal: Japanese journal of clinical oncology 20121001
Title: CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
Journal: Journal of neuro-oncology 20121001
Title: Therapeutic targeting of VEGF in the treatment of glioblastoma.
Journal: Expert opinion on therapeutic targets 20121001
Title: ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.
Journal: Stem cells (Dayton, Ohio) 20121001
Title: Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases.
Journal: Cancer chemotherapy and pharmacology 20121001
Title: Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells.
Journal: Autophagy 20121001
Title: Prognosis of patients with multifocal glioblastoma: a case-control study.
Journal: Journal of neurosurgery 20121001
Title: Beyond ABC: another mechanism of drug resistance in melanoma side population.
Journal: The Journal of investigative dermatology 20121001
Title: The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy.
Journal: Journal of medical imaging and radiation oncology 20121001
Title: Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
Journal: Anticancer research 20121001
Title: The Changes in MGMT Promoter Methylation Status in Initial and Recurrent Glioblastomas.
Journal: Translational oncology 20121001
Title: BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.
Journal: Cell death & disease 20121001
Title: O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy with concomitant and adjuvant temozolomide.
Journal: Cancer 20120915
Title: Sequence-dependent synergistic inhibition of human glioma cell lines by combined temozolomide and miR-21 inhibitor gene therapy.
Journal: Molecular pharmaceutics 20120904
Title: Pituitary blastoma: a unique embryonal tumor.
Journal: Pituitary 20120901
Title: Anti-VEGF therapy in pituitary carcinoma.
Journal: Pituitary 20120901
Title: MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations.
Journal: International journal of cancer 20120901
Title: Temozolomide responsiveness in aggressive corticotroph tumours: a case report and review of the literature.
Journal: Pituitary 20120901
Title: Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study.
Journal: Medical oncology (Northwood, London, England) 20120901
Title: Improving prognosis of glioblastoma in the 21st century: who has benefited most?
Journal: Cancer 20120901
Title: A clinical review of treatment outcomes in glioblastoma multiforme--the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival?
Journal: The British journal of radiology 20120901
Title: Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients.
Journal: Clinical neurology and neurosurgery 20120901
Title: AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenografts.
Journal: Cancer chemotherapy and pharmacology 20120901
Title: Temozolomide or bevacizumab for spinal cord high-grade gliomas.
Journal: Journal of neuro-oncology 20120901
Title: Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.
Journal: Journal of neuro-oncology 20120901
Title: Knockdown of CDK6 enhances glioma sensitivity to chemotherapy.
Journal: Oncology reports 20120901
Title: Procarbazine, carmustine, and vincristine (PBV) for chemotherapy pre-treated patients with recurrent glioblastoma: a single-institution analysis.
Journal: Journal of neuro-oncology 20120901
Title: Loss of TP53 expression in immortalized choroid plexus epithelial cells results in increased resistance to anticancer agents.
Journal: Journal of neuro-oncology 20120901
Title: Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.
Journal: Journal of neuro-oncology 20120901
Title: Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells.
Journal: Oncology reports 20120901
Title: An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120901
Title: p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50.
Journal: Neuro-oncology 20120901
Title: A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme.
Journal: Neuro-oncology 20120901
Title: Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
Journal: The Lancet. Oncology 20120901
Title: Glioblastoma therapy in the elderly: one age does not fit all.
Journal: The Lancet. Oncology 20120901
Title: Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901
Title: New treatment options with cytotoxic agents in neuroendocrine tumours.
Journal: Targeted oncology 20120901
Title: Prognostic relevance of c-Myc and BMI1 expression in patients with glioblastoma.
Journal: American journal of clinical pathology 20120901
Title: Hypofractionated radiotherapy for glioblastoma: strategy for poor-risk patients or hope for the future?
Journal: The British journal of radiology 20120901
Title: Temozolomide for relapsed primary CNS lymphoma.
Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20120901
Title: A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma.
Journal: Anticancer research 20120901
Title: [Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme].
Journal: Magyar onkologia 20120901
Title: Non-uniform response to temozolomide therapy in a pituitary gonadotroph adenoma.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20120901
Title: Constitutive Expression of MAP Kinase Phosphatase-1 Confers Multi-drug Resistance in Human Glioblastoma Cells.
Journal: Cancer research and treatment : official journal of Korean Cancer Association 20120901
Title: Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice.
Journal: Neuro-oncology 20120901
Title: Seizures in low-grade gliomas: natural history, pathogenesis, and outcome after treatments.
Journal: Neuro-oncology 20120901
Title: A restricted cell population propagates glioblastoma growth after chemotherapy.
Journal: Nature 20120823
Title: Cancer: Resolving the stem-cell debate.
Journal: Nature 20120823
Title: Prospective study of bevacizumab plus temozolomide in patients with advanced neuroendocrine tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120820
Title: Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells, and induction of a cytoprotective autophagic response.
Journal: International journal of cancer 20120815
Title: Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
Journal: Journal of complementary & integrative medicine 20120810
Title: O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems.
Journal: Biochimica et biophysica acta 20120801
Title: Cilengitide in bevacizumab-refractory high-grade glioma: two case reports and critical review of the literature.
Journal: Anti-cancer drugs 20120801
Title: A multicenter prospective observational study of the conformity of temozolomide prescriptions in France.
Journal: Pharmacoepidemiology and drug safety 20120801
Title: Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
Journal: The American journal of surgical pathology 20120801
Title: Treatment-related toxicities in tumor-bearing cats treated with temozolomide alone or in combination with doxorubicin: a pilot assessment.
Journal: Journal of feline medicine and surgery 20120801
Title: Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.
Journal: Journal of neuro-oncology 20120801
Title: Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.
Journal: Biomaterials 20120801
Title: Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.
Journal: Journal of neuro-oncology 20120801
Title: Predictive value of the MGMT promoter methylation status in metastatic melanoma patients receiving first-line temozolomide plus bevacizumab in the trial SAKK 50/07.
Journal: Oncology reports 20120801
Title: In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model.
Journal: Cancer gene therapy 20120801
Title: Waiting times before initiation of radiotherapy might not affect outcomes for patients with glioblastoma: a French retrospective analysis of patients treated in the era of concomitant temozolomide and radiotherapy.
Journal: Journal of neuro-oncology 20120801
Title: Anaplastic glioma.
Journal: Current treatment options in neurology 20120801
Title: Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120801
Title: Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.
Journal: Acta neurochirurgica 20120801
Title: Quantitative proteomic analysis and functional studies reveal that nucleophosmin is involved in cell death in glioblastoma cell line transfected with siRNA.
Journal: Proteomics 20120801
Title: Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer.
Journal: Bioorganic & medicinal chemistry 20120801
Title: Recent innovations in the management of low-grade gliomas.
Journal: Current treatment options in neurology 20120801
Title: N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.
Journal: Cell research 20120801
Title: N-Aryl-N'-(chroman-4-yl)ureas and thioureas display in vitro anticancer activity and selectivity on apoptosis-resistant glioblastoma cells: screening, synthesis of simplified derivatives, and structure-activity relationship analysis.
Journal: European journal of medicinal chemistry 20120801
Title: Does neurologic deterioration help to differentiate between pseudoprogression and true disease progression in newly diagnosed glioblastoma multiforme?
Journal: Current oncology (Toronto, Ont.) 20120801
Title: Bevacizumab as first-line therapy for glioblastoma.
Journal: Future oncology (London, England) 20120801
Title: Role for cytotoxic chemotherapy in patients with recurrent glioblastoma progressing on bevacizumab: a retrospective case series.
Journal: Expert review of neurotherapeutics 20120801
Title: Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas : A Prospective Multicenter Study of Korean Patients.
Journal: Journal of Korean Neurosurgical Society 20120801
Title: Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120720
Title: Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro.
Journal: Oncogene 20120719
Title: In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.
Journal: International journal of cancer 20120715
Title: Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.
Journal: Cancer research 20120715
Title: Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120715
Title: Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.
Journal: International journal of cancer 20120701
Title: Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers.
Journal: Neurotoxicity research 20120701
Title: Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
Journal: Journal of cellular biochemistry 20120701
Title: Key concepts in glioblastoma therapy.
Journal: Journal of neurology, neurosurgery, and psychiatry 20120701
Title: Treatment of a solid tumor using engineered drug-resistant immunocompetent cells and cytotoxic chemotherapy.
Journal: Human gene therapy 20120701
Title: Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy.
Journal: Journal of neuro-oncology 20120701
Title: Bevacizumab is an active agent for recurrent high-grade glioma, but do we need randomized controlled trials?
Journal: Anti-cancer drugs 20120701
Title: Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.
Journal: Journal of neuro-oncology 20120701
Title: Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma.
Journal: International journal of pharmaceutics 20120701
Title: Combined therapy of temozolomide and ZD6474 (vandetanib) effectively reduces glioblastoma tumor volume through anti-angiogenic and anti-proliferative mechanisms.
Journal: Molecular medicine reports 20120701
Title: Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature.
Journal: Clinical neurology and neurosurgery 20120701
Title: Fatal pneumonia associated with temozolomide therapy in patients with malignant glioma.
Journal: Japanese journal of clinical oncology 20120701
Title: Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway.
Journal: CNS neuroscience & therapeutics 20120701
Title: Drug-induced cholestatic hepatitis: how late can it occur even after the cessation of the culpable drug?
Journal: Neuro-oncology 20120701
Title: Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120701
Title: Treatment of elderly patients with glioblastoma.
Journal: The Lancet. Oncology 20120701
Title: Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
Journal: The Lancet. Oncology 20120701
Title: New substituted 4H-chromenes as anticancer agents.
Journal: Bioorganic & medicinal chemistry letters 20120701
Title: Bevacizumab plus irinotecan in recurrent malignant glioma shows high overall survival in a multicenter retrospective pooled series of the Spanish Neuro-Oncology Research Group (GEINO).
Journal: Anti-cancer drugs 20120701
Title: The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas.
Journal: Cancer chemotherapy and pharmacology 20120701
Title: Assessment of treatment response in patients with glioblastoma using O-(2-18F-fluoroethyl)-L-tyrosine PET in comparison to MRI.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120701
Title: FET-PET assessed recurrence pattern after radio-chemotherapy in newly diagnosed patients with glioblastoma is influenced by MGMT methylation status.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120701
Title: Potential usefulness of radiosensitizers in glioblastoma.
Journal: Neurosurgery clinics of North America 20120701
Title: MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.
Journal: Anticancer research 20120701
Title: New molecularly targeted therapies for glioblastoma multiforme.
Journal: Anticancer research 20120701
Title: Chemotherapy-associated steatohepatitis with temozolomide and dexamethasone.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20120701
Title: Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones.
Journal: Biochemical pharmacology 20120615
Title: Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide.
Journal: American journal of clinical oncology 20120601
Title: MRI and thallium-201 SPECT in the prediction of survival in glioma.
Journal: Neuroradiology 20120601
Title: Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis.
Journal: International journal of clinical oncology 20120601
Title: Temozolomide plus radiotherapy for glioblastoma in a Canadian province: efficacy versus effectiveness and the impact of O6-methylguanine-DNA-methyltransferase promoter methylation.
Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20120601
Title: Effect of valproic acid on the outcome of glioblastoma multiforme.
Journal: British journal of neurosurgery 20120601
Title: Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.
Journal: Acta neuropathologica 20120601
Title: Factors affecting the cerebral network in brain tumor patients.
Journal: Journal of neuro-oncology 20120601
Title: Cognition and resective surgery for diffuse infiltrative glioma: an overview.
Journal: Journal of neuro-oncology 20120601
Title: Temozolomide in the management of dopamine agonist-resistant prolactinomas.
Journal: Clinical endocrinology 20120601
Title: Pituitary carcinomas and aggressive pituitary tumours: merits and pitfalls of temozolomide treatment.
Journal: Clinical endocrinology 20120601
Title: Resveratrol reverses temozolomide resistance by downregulation of MGMT in T98G glioblastoma cells by the NF-κB-dependent pathway.
Journal: Oncology reports 20120601
Title: Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system.
Journal: Biomaterials 20120601
Title: A SDHB malignant paraganglioma with dramatic response to temozolomide-capecitabine.
Journal: European journal of endocrinology 20120601
Title: Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?
Journal: Current oncology reports 20120601
Title: Temozolomide dosing regimens for glioma patients.
Journal: Current neurology and neuroscience reports 20120601
Title: SSBP2 variants are associated with survival in glioblastoma patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120601
Title: Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment.
Journal: Annales d'endocrinologie 20120601
Title: MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide.
Journal: Journal of molecular neuroscience : MN 20120601
Title: STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression.
Journal: Molecular cancer therapeutics 20120601
Title: Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology).
Journal: Neuro-oncology 20120601
Title: miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression.
Journal: Neuro-oncology 20120601
Title: Initial treatment patterns over time for anaplastic oligodendroglial tumors.
Journal: Neuro-oncology 20120601
Title: Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
Journal: Acta cirurgica brasileira 20120601
Title: Systemic therapy for advanced pancreatic neuroendocrine tumors: an update.
Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20120601
Title: Management of glioblastoma in the elderly.
Journal: Clinical advances in hematology & oncology : H&O 20120601
Title: Challenges in drug delivery to tumors of the central nervous system: an overview of pharmacological and surgical considerations.
Journal: Advanced drug delivery reviews 20120515
Title: Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20120501
Title: Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery.
Journal: International journal of radiation oncology, biology, physics 20120501
Title: An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing.
Journal: Journal of neuro-oncology 20120501
Title: Recent advances in the molecular understanding of glioblastoma.
Journal: Journal of neuro-oncology 20120501
Title: Prognostic significance of MRP5 immunohistochemical expression in glioblastoma.
Journal: Cancer chemotherapy and pharmacology 20120501
Title: Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.
Journal: Journal of neuro-oncology 20120501
Title: CXCL12 mediates apoptosis resistance in rat C6 glioma cells.
Journal: Oncology reports 20120501
Title: Marked response of gliomatosis cerebri to temozolomide and whole brain radiotherapy.
Journal: Clinical neurology and neurosurgery 20120501
Title: Myc proteins in brain tumor development and maintenance.
Journal: Upsala journal of medical sciences 20120501
Title: Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme.
Journal: Journal of neuro-oncology 20120501
Title: The effects of temozolomide delivered by prolonged intracerebral microinfusion against the rat brainstem GBM allograft model.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120501
Title: Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
Journal: Neuro-oncology 20120501
Title: Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.
Journal: Journal of neuro-oncology 20120501
Title: Successful pregnancy and delivery after concomitant temozolomide and radiotherapy treatment of glioblastoma multiforme.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20120501
Title: Treatment-related myelodysplasia in patients with primary brain tumors.
Journal: Neuro-oncology 20120501
Title: In vitro evaluation of combined temozolomide and radiotherapy using X rays and high-linear energy transfer radiation for glioblastoma.
Journal: Radiation research 20120501
Title: Neural stem cells: brain building blocks and beyond.
Journal: Upsala journal of medical sciences 20120501
Title: Glioblastoma--a moving target.
Journal: Upsala journal of medical sciences 20120501
Title: Possible differentiation of cerebral glioblastoma into pleomorphic xanthoastrocytoma: an unusual case in an infant.
Journal: Journal of neurosurgery. Pediatrics 20120501
Title: Phase 2 trial design in neuro-oncology revisited: a report from the RANO group.
Journal: The Lancet. Oncology 20120501
Title: [Genetic alterations and biomarkers for glioma].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20120501
Title: Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation.
Journal: PLoS biology 20120501
Title: Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.
Journal: Expert review of anticancer therapy 20120501
Title: Radiation necrosis of a high-grade glioma.
Journal: Medicine and health, Rhode Island 20120501
Title: Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.
Journal: Cancer 20120415
Title: 3'-5' phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo.
Journal: The Biochemical journal 20120415
Title: Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.
Journal: Journal of medicinal chemistry 20120412
Title: A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial.
Journal: Investigational new drugs 20120401
Title: Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas.
Journal: International journal of radiation oncology, biology, physics 20120401
Title: The concepts, diagnosis and management of early imaging changes after therapy for glioblastomas.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20120401
Title: Cerebellar gliomatosis in a toddler: case report of a challenging condition and review of the literature.
Journal: Journal of child neurology 20120401
Title: Glioblastoma survival in the United States before and during the temozolomide era.
Journal: Journal of neuro-oncology 20120401
Title: Salvage gamma knife stereotactic radiosurgery followed by bevacizumab for recurrent glioblastoma multiforme: a case-control study.
Journal: Journal of neuro-oncology 20120401
Title: Spinal cord glioneuronal tumor with neuropil-like islands with 1p/19q deletion in an adult with low-grade cerebral oligodendroglioma.
Journal: Journal of neuro-oncology 20120401
Title: High levels of cellular proliferation predict pseudoprogression in glioblastoma patients.
Journal: International journal of oncology 20120401
Title: Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
Journal: Journal of neuro-oncology 20120401
Title: Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience.
Journal: Journal of neuro-oncology 20120401
Title: Going past the data for temozolomide.
Journal: Cancer chemotherapy and pharmacology 20120401
Title: Complete remission after bevacizumab plus temozolomide in a patient with recurrent glioblastoma multiforme.
Journal: Acta oncologica (Stockholm, Sweden) 20120401
Title: Temozolomide for pediatric high-grade gliomas.
Journal: Current neurology and neuroscience reports 20120401
Title: Responsive fluorescent Bi(2)O(3)@PVA hybrid nanogels for temperature-sensing, dual-modal imaging, and drug delivery.
Journal: Biomaterials 20120401
Title: PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma.
Journal: Cancer research 20120401
Title: Phase I study of terameprocol in patients with recurrent high-grade glioma.
Journal: Neuro-oncology 20120401
Title: Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
Journal: Neuro-oncology 20120401
Title: Pseudoprogression and treatment effect.
Journal: Neurosurgery clinics of North America 20120401
Title: Alternative chemotherapeutic agents: nitrosoureas, cisplatin, irinotecan.
Journal: Neurosurgery clinics of North America 20120401
Title: Temozolomide and other potential agents for the treatment of glioblastoma multiforme.
Journal: Neurosurgery clinics of North America 20120401
Title: Superselective intra-arterial cerebral infusion of novel agents after blood-brain disruption for the treatment of recurrent glioblastoma multiforme: a technical case series.
Journal: Neurosurgery clinics of North America 20120401
Title: The role of avastin in the management of recurrent glioblastoma.
Journal: Neurosurgery clinics of North America 20120401
Title: Temozolomide-associated bronchiolitis obliterans organizing pneumonia successfully treated with high-dose corticosteroid.
Journal: Journal of Korean medical science 20120401
Title: Decreased expression of the augmenter of liver regeneration results in increased apoptosis and oxidative damage in human-derived glioma cells.
Journal: Cell death & disease 20120401
Title: Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme.
Journal: Journal of medical imaging and radiation oncology 20120401
Title: Treatment of nonfunctioning pituitary adenomas: what were the contributions of the last 10 years? A critical view.
Journal: Annales d'endocrinologie 20120401
Title: Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Journal: Archives of medical research 20120401
Title: Temozolomide in aggressive pituitary adenomas and carcinomas.
Journal: Clinics (Sao Paulo, Brazil) 20120401
Title: Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
Journal: Clinical advances in hematology & oncology : H&O 20120401
Title: Helping patients make the best decision regarding duration of temozolomide chemotherapy treatment.
Journal: Continuum (Minneapolis, Minn.) 20120401
Title: Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control.
Journal: Cell cycle (Georgetown, Tex.) 20120315
Title: Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
Journal: Journal of medicinal chemistry 20120308
Title: Failure of temozolomide and conventional doses of pegvisomant to attain biochemical control in a severe case of acromegaly.
Journal: Pituitary 20120301
Title: Response to temozolomide and bevacizumab in a patient with poorly differentiated neuroendocrine carcinoma.
Journal: Medical oncology (Northwood, London, England) 20120301
Title: Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.
Journal: International journal of cancer 20120301
Title: Bevacizumab and daily temozolomide for recurrent glioblastoma.
Journal: Cancer 20120301
Title: New targeted therapies in pituitary carcinoma resistant to temozolomide.
Journal: Pituitary 20120301
Title: O⁶-methylguanine-DNA methyltransferase promoter methylation in 45 primary central nervous system lymphomas: quantitative assessment of methylation and response to temozolomide treatment.
Journal: Journal of neuro-oncology 20120301
Title: Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.
Journal: Journal of neuro-oncology 20120301
Title: Improved survival time trends for glioblastoma using the SEER 17 population-based registries.
Journal: Journal of neuro-oncology 20120301
Title: Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.
Journal: Journal of neuro-oncology 20120301
Title: Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status.
Journal: Oncology reports 20120301
Title: Therapeutical doses of temozolomide do not impair the function of dendritic cells and CD8+ T cells.
Journal: International journal of oncology 20120301
Title: Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
Journal: Neuro-oncology 20120301
Title: Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
Journal: Journal of cancer research and clinical oncology 20120301
Title: Anti-angiogenic approaches to malignant gliomas.
Journal: Current cancer drug targets 20120301
Title: Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006.
Journal: Neuro-oncology 20120301
Title: Targeted therapy for brain tumours: role of PARP inhibitors.
Journal: Current cancer drug targets 20120301
Title: Functional diffusion maps (fDMs) evaluated before and after radiochemotherapy predict progression-free and overall survival in newly diagnosed glioblastoma.
Journal: Neuro-oncology 20120301
Title: A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054).
Journal: Neuro-oncology 20120301
Title: Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?
Journal: Endocrine pathology 20120301
Title: Pituitary carcinoma recurrent to the lumbar intradural extramedullary space: case report.
Journal: The journal of spinal cord medicine 20120301
Title: Adult brainstem gliomas.
Journal: The oncologist 20120301
Title: Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma.
Journal: Anticancer research 20120301
Title: The expression of p-STAT3 in stage IV melanoma: risk of CNS metastasis and survival.
Journal: Oncotarget 20120301
Title: Extraneural metastasis of glioblastoma multiforme presenting as an unusual neck mass.
Journal: Journal of Korean Neurosurgical Society 20120301
Title: Autophagy and cancer.
Journal: Experimental & molecular medicine 20120227
Title: The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models.
Journal: British journal of cancer 20120227
Title: Progression-free and overall survival in patients with relapsed/refractory germ cell tumors treated with single-agent chemotherapy: endpoints for clinical trial design.
Journal: Cancer 20120215
Title: Phase II trial of temozolomide in patients with relapsed sensitive or refractory small cell lung cancer, with assessment of methylguanine-DNA methyltransferase as a potential biomarker.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
Title: Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
Title: Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas.
Journal: Oncogene 20120209
Title: A phase I dose escalation study of hypofractionated IMRT field-in-field boost for newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20120201
Title: Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.
Journal: International journal of radiation oncology, biology, physics 20120201
Title: Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma.
Journal: International journal of radiation oncology, biology, physics 20120201
Title: First-line temozolomide combined with bevacizumab in metastatic melanoma: a multicentre phase II trial (SAKK 50/07).
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120201
Title: O-6-methylguanine-DNA methyltransferase (MGMT) immunohistochemical expression in pituitary corticotroph adenomas.
Journal: Neurosurgery 20120201
Title: A phase I study of bortezomib and temozolomide in patients with advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20120201
Title: A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.
Journal: Journal of neuro-oncology 20120201
Title: New treatment strategies in advanced neuroendocrine tumours.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120201
Title: Efficacy and toxicity of CyberKnife re-irradiation and 'dose dense' temozolomide for recurrent gliomas.
Journal: Acta neurochirurgica 20120201
Title: Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
Journal: Acta neurochirurgica 20120201
Title: IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma.
Journal: Cancer science 20120201
Title: Avastin: more questions than answers. .
Journal: Journal of neurosurgery 20120201
Title: A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
Journal: Journal of neurosurgery 20120201
Title: LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway.
Journal: Molecular medicine reports 20120201
Title: Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Cancer Research (SAKK 70/03).
Journal: European journal of cancer (Oxford, England : 1990) 20120201
Title: Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI.
Journal: Biomaterials 20120201
Title: Gastroenteropancreatic neuroendocrine tumors: new insights in the diagnosis and therapy.
Journal: Endocrine 20120201
Title: Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor.
Journal: Molecular cancer therapeutics 20120201
Title: Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.
Journal: Nature genetics 20120201
Title: Reoxygenation of glioblastoma multiforme treated with fractionated radiotherapy concomitant with temozolomide: changes defined by 18F-fluoromisonidazole positron emission tomography: two case reports.
Journal: Japanese journal of clinical oncology 20120201
Title: Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20120201
Title: Radiotherapy with and without temozolomide in elderly patients with glioblastoma.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20120201
Title: Combination treatment with metronomic temozolomide, bevacizumab and long-acting octreotide for malignant neuroendocrine tumours.
Journal: Endocrine-related cancer 20120201
Title: [Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
Journal: Bulletin du cancer 20120201
Title: Whole-brain irradiation with concomitant daily fixed-dose temozolomide for brain metastases treatment: a randomised phase II trial.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120201
Title: [Analyses of IDH1 mutation and MGMT promoter methylation status for 5 cases of long-term survivors with glioblastoma].
Journal: No shinkei geka. Neurological surgery 20120201
Title: [Comparison of two regimens of postoperative concurrent chemoradiotherapy in adult patients with grade III-IV cerebral gliomas].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201
Title: Glioblastoma following radiosurgery for meningioma.
Journal: Journal of Korean Neurosurgical Society 20120201
Title: Polymodal therapy for high grade gliomas: a case report of favourable outcomes following intraoperative radiation therapy.
Journal: The Medical journal of Malaysia 20120201
Title: PARP-1 protein expression in glioblastoma multiforme.
Journal: European journal of histochemistry : EJH 20120120
Title: TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.
Journal: International journal of cancer 20120115
Title: Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120115
Title: Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
Journal: Free radical biology & medicine 20120115
Title: Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120115
Title: Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
Journal: Journal of the National Cancer Institute 20120104
Title: Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
Journal: The Journal of clinical investigation 20120103
Title: Developing and paying for medicines for orphan indications in oncology: utilitarian regulation vs equitable care?
Journal: British journal of cancer 20120103
Title: Enhancing melanoma treatment with resveratrol.
Journal: The Journal of surgical research 20120101
Title: Irradiation and bevacizumab in high-grade glioma retreatment settings.
Journal: International journal of radiation oncology, biology, physics 20120101
Title: Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas.
Journal: International journal of radiation oncology, biology, physics 20120101
Title: Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20120101
Title: Hematologic adverse events associated with temozolomide.
Journal: Cancer chemotherapy and pharmacology 20120101
Title: Salvage treatment with temozolomide in refractory or relapsed primary central nervous system lymphoma and assessment of the MGMT status.
Journal: Journal of neuro-oncology 20120101
Title: Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression.
Journal: Journal of neuro-oncology 20120101
Title: Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.
Journal: Journal of neuro-oncology 20120101
Title: Combination of neoadjuvant chemotherapy followed by surgical resection as a new strategy for WHO grade II gliomas: a study of cognitive status and quality of life.
Journal: Journal of neuro-oncology 20120101
Title: Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas.
Journal: Journal of oncology 20120101
Title: Anaplastic ependymoma simulating glioblastoma in the cerebrum of an adult.
Journal: Brain tumor pathology 20120101
Title: Type 2 diabetes mellitus and obesity are independent risk factors for poor outcome in patients with high-grade glioma.
Journal: Journal of neuro-oncology 20120101
Title: Subcutaneous tumor seeding after biopsy in gliomatosis cerebri.
Journal: Journal of neuro-oncology 20120101
Title: Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.
Journal: Journal of neuro-oncology 20120101
Title: Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120101
Title: MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis.
Journal: International journal of oncology 20120101
Title: Chemoresistance to temozolomide in human glioma cell line U251 is associated with increased activity of O6-methylguanine-DNA methyltransferase and can be overcome by metronomic temozolomide regimen.
Journal: Cell biochemistry and biophysics 20120101
Title: The Role of PTEN in Tumor Angiogenesis.
Journal: Journal of oncology 20120101
Title: Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Novel medical therapies of recurrent and metastatic gastroenteropancreatic neuroendocrine tumors.
Journal: Digestive diseases and sciences 20120101
Title: Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents.
Journal: Pigment cell & melanoma research 20120101
Title: New criteria for analyzing the statistical relationships between biological parameters and therapeutic responses of xenografted tumor models.
Journal: Contemporary clinical trials 20120101
Title: Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study.
Journal: Neuro-oncology 20120101
Title: Ipilimumab, a promising immunotherapy with increased overall survival in metastatic melanoma?
Journal: Dermatology research and practice 20120101
Title: Co-delivery of pEGFP-hTRAIL and paclitaxel to brain glioma mediated by an angiopep-conjugated liposome.
Journal: Biomaterials 20120101
Title: Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).
Journal: Gut 20120101
Title: Tailored temozolomide therapy according to MGMT methylation status for elderly patients with acute myeloid leukemia.
Journal: American journal of hematology 20120101
Title: Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120101
Title: Basal breast cancer: a complex and deadly molecular subtype.
Journal: Current molecular medicine 20120101
Title: Biomarkers as key contributors in treating malignant melanoma metastases.
Journal: Dermatology research and practice 20120101
Title: Evolving drug targets in DNA base excision repair for cancer therapy.
Journal: Current molecular pharmacology 20120101
Title: Overview of base excision repair biochemistry.
Journal: Current molecular pharmacology 20120101
Title: Temozolomide: mechanisms of action, repair and resistance.
Journal: Current molecular pharmacology 20120101
Title: Bevacizumab in glioblastoma multiforme.
Journal: Expert review of anticancer therapy 20120101
Title: Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Fluctuation of systemic immunity in melanoma and implications for timing of therapy.
Journal: Frontiers in bioscience (Elite edition) 20120101
Title: Improved synthesis strategy for peptide nucleic acids (PNA) appropriate for cell-specific fluorescence imaging.
Journal: International journal of medical sciences 20120101
Title: Volumetric and MGMT parameters in glioblastoma patients: survival analysis.
Journal: BMC cancer 20120101
Title: Targeting the Cellular Signaling: BRAF Inhibition and Beyond for the Treatment of Metastatic Malignant Melanoma.
Journal: Dermatology research and practice 20120101
Title: Successful treatment of leptomeningeal gliomatosis of pilomyxoid astrocytoma after failed frontline chemotherapy.
Journal: The neurologist 20120101
Title: Neurological complications of chemotherapy to the central nervous system.
Journal: Handbook of clinical neurology 20120101
Title: Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1.
Journal: Journal of translational medicine 20120101
Title: Ovarian cancer: opportunity for targeted therapy.
Journal: Journal of oncology 20120101
Title: Glucosylceramide synthase protects glioblastoma cells against autophagic and apoptotic death induced by temozolomide and Paclitaxel.
Journal: Cancer investigation 20120101
Title: Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.
Journal: Cell death & disease 20120101
Title: Exposure to N-ethyl-N-nitrosourea in adult mice alters structural and functional integrity of neurogenic sites.
Journal: PloS one 20120101
Title: A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis.
Journal: PLoS computational biology 20120101
Title: Eosinophils in glioblastoma biology.
Journal: Journal of neuroinflammation 20120101
Title: Aflibercept in the treatment of metastatic colorectal cancer.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Novel treatments for metastatic cutaneous melanoma and the management of emergent toxicities.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Prediction of glioblastoma multiform response to bevacizumab treatment using multi-parametric MRI.
Journal: PloS one 20120101
Title: Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia.
Journal: PloS one 20120101
Title: Methylation status of O6-methylguanine-DNA-methyl transferase promoter region in non-small-cell lung cancer patients with brain metastasis.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20120101
Title: Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas.
Journal: Diagnostic pathology 20120101
Title: Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.
Journal: Theranostics 20120101
Title: Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse models.
Journal: Oncotarget 20120101
Title: Status quo--standard-of-care medical and radiation therapy for glioblastoma.
Journal: Cancer journal (Sudbury, Mass.) 20120101
Title: Neuroimaging: diagnosis and response assessment in glioblastoma.
Journal: Cancer journal (Sudbury, Mass.) 20120101
Title: Monoclonal antibodies and Fc fragments for treating solid tumors.
Journal: Biologics : targets & therapy 20120101
Title: Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China.
Journal: PloS one 20120101
Title: Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas.
Journal: PloS one 20120101
Title: Current Status of Poly(ADP-ribose) Polymerase Inhibitors as Novel Therapeutic Agents for Triple-Negative Breast Cancer.
Journal: International journal of breast cancer 20120101
Title: Neoplastic cells are a rare component in human glioblastoma microvasculature.
Journal: Oncotarget 20120101
Title: The effect of temozolomide/poly(lactide-co-glycolide) (PLGA)/nano-hydroxyapatite microspheres on glioma U87 cells behavior.
Journal: International journal of molecular sciences 20120101
Title: Modulation of tumor tolerance in primary central nervous system malignancies.
Journal: Clinical & developmental immunology 20120101
Title: Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.
Journal: Stem cell research & therapy 20120101
Title: Current management and novel agents for malignant melanoma.
Journal: Journal of hematology & oncology 20120101
Title: Sendai virus-based liposomes enable targeted cytosolic delivery of nanoparticles in brain tumor-derived cells.
Journal: Journal of nanobiotechnology 20120101
Title: The monoclonal antibody to cytotoxic T lymphocyte antigen 4, ipilimumab, in the treatment of melanoma.
Journal: Cancer management and research 20120101
Title: Treatment Options in Cushing's Disease.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Implementing preclinical study findings to protocol design: translational studies with alloreactive CTL for gliomas.
Journal: American journal of translational research 20120101
Title: Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma.
Journal: PloS one 20120101
Title: A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.
Journal: PloS one 20120101
Title: Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.
Journal: PloS one 20120101
Title: Therapy for metastatic melanoma: the past, present, and future.
Journal: BMC medicine 20120101
Title: Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.
Journal: PloS one 20120101
Title: MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR.
Journal: Journal of translational medicine 20120101
Title: Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment.
Journal: PloS one 20120101
Title: Iodine-125 brachytherapy for brain tumours--a review.
Journal: Radiation oncology (London, England) 20120101
Title: Toxin-based targeted therapy for malignant brain tumors.
Journal: Clinical & developmental immunology 20120101
Title: β-Catenin Signalling in Glioblastoma Multiforme and Glioma-Initiating Cells.
Journal: Chemotherapy research and practice 20120101
Title: Methodology for Anti-Gene Anti-IGF-I Therapy of Malignant Tumours.
Journal: Chemotherapy research and practice 20120101
Title: Detection of 1p19q deletion by real-time comparative quantitative PCR.
Journal: Biomarker insights 20120101
Title: In vitro and in vivo studies on gelatin-siloxane nanoparticles conjugated with SynB peptide to increase drug delivery to the brain.
Journal: International journal of nanomedicine 20120101
Title: Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications.
Journal: International journal of nanomedicine 20120101
Title: The limitations of locus specific methylation qualification and quantification in clinical material.
Journal: Frontiers in genetics 20120101
Title: Intra-arterial delivery of bevacizumab after blood-brain barrier disruption for the treatment of recurrent glioblastoma: progression-free survival and overall survival.
Journal: World neurosurgery 20120101
Title: RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β₃ expression.
Journal: International journal of nanomedicine 20120101
Title: PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck.
Journal: PloS one 20120101
Title: Emerging treatment options for the treatment of neuroblastoma: potential role of perifosine.
Journal: OncoTargets and therapy 20120101
Title: Targeted agents for the treatment of metastatic melanoma.
Journal: OncoTargets and therapy 20120101
Title: Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases.
Journal: Frontiers in pharmacology 20120101
Title: Pediatric cerebellar hemorrhagic glioblastoma multiforme.
Journal: The open neuroimaging journal 20120101
Title: Low levels of Human Cytomegalovirus Infection in Glioblastoma multiforme associates with patient survival; -a case-control study.
Journal: Herpesviridae 20120101
Title: Co-deletion of chromosome 1p/19q and IDH1/2 mutation in glioma subsets of brain tumors in Chinese patients.
Journal: PloS one 20120101
Title: Topical application of activity-based probes for visualization of brain tumor tissue.
Journal: PloS one 20120101
Title: Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma.
Journal: PloS one 20120101
Title: The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond.
Journal: TheScientificWorldJournal 20120101
Title: NF-κB as potential target in the treatment of melanoma.
Journal: Journal of translational medicine 20120101
Title: Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts.
Journal: Radiation oncology (London, England) 20120101
Title: Efficacy and tolerability of lapatinib in the management of breast cancer.
Journal: Breast cancer : basic and clinical research 20120101
Title: Comparison of intensity modulated radiotherapy (IMRT) with intensity modulated particle therapy (IMPT) using fixed beams or an ion gantry for the treatment of patients with skull base meningiomas.
Journal: Radiation oncology (London, England) 20120101
Title: Classification, molecular characterization, and the significance of pten alteration in leiomyosarcoma.
Journal: Sarcoma 20120101
Title: Atypical, invasive, recurring Crooke cell adenoma of the pituitary.
Journal: Hormones (Athens, Greece) 20120101
Title: Association between a Primitive Brain Tumor and Cerebral Aspergillosis.
Journal: Case reports in medicine 20120101
Title: Use of a deformable atlas to identify cryptic critical structures in the treatment of glioblastoma multiforme.
Journal: PloS one 20120101
Title: Glioblastoma multiforme: novel therapeutic approaches.
Journal: ISRN neurology 20120101
Title: Monitoring of patients treated with particle therapy using positron-emission-tomography (PET): the MIRANDA study.
Journal: BMC cancer 20120101
Title: Cellular-based immunotherapies for patients with glioblastoma multiforme.
Journal: Clinical & developmental immunology 20120101
Title: Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.
Journal: PloS one 20120101
Title: Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival.
Journal: Molecular cancer 20120101
Title: An observational study of the first experience with bevacizumab for the treatment of patients with recurrent high-grade glioma in two belgian university hospitals.
Journal: Journal of oncology 20120101
Title: Akt: a double-edged sword in cell proliferation and genome stability.
Journal: Journal of oncology 20120101
Title: Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients.
Journal: PloS one 20120101
Title: Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
Journal: PloS one 20120101
Title: In vitro and in vivo antagonism of a G protein-coupled receptor (S1P3) with a novel blocking monoclonal antibody.
Journal: PloS one 20120101
Title: CD24 expression as a marker for predicting clinical outcome in human gliomas.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Targeting costimulatory molecules to improve antitumor immunity.
Journal: Journal of biomedicine & biotechnology 20120101
Title: The ketogenic diet as a treatment paradigm for diverse neurological disorders.
Journal: Frontiers in pharmacology 20120101
Title: Subgroup economic analysis for glioblastoma in a health resource-limited setting.
Journal: PloS one 20120101
Title: Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro.
Journal: Journal of Cancer 20120101
Title: Contribution of low-molecular weight heparin addition to concomitant chemoradiotherapy in the treatment of glioblastoma multiforme.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20120101
Title: Treatment of liver metastases in patients with neuroendocrine tumors of gastroesophageal and pancreatic origin.
Journal: International journal of hepatology 20120101
Title: A multimodal approach to the management of neuroendocrine tumour liver metastases.
Journal: International journal of hepatology 20120101
Title: A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma.
Journal: PloS one 20120101
Title: The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries.
Journal: Journal of signal transduction 20120101
Title: miRNAs expression analysis in paired fresh/frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time pCR.
Journal: PloS one 20120101
Title: Novel therapies in glioblastoma.
Journal: Neurology research international 20120101
Title: The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas.
Journal: Neurology research international 20120101
Title: Current trends in targeted therapies for glioblastoma multiforme.
Journal: Neurology research international 20120101
Title: Survival outcome and neurotoxicity in patients of high-grade gliomas treated with conformal radiation and temozolamide.
Journal: Journal of cancer research and therapeutics 20120101
Title: Cell cycle gene networks are associated with melanoma prognosis.
Journal: PloS one 20120101
Title: Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence.
Journal: PloS one 20120101
Title: Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials.
Journal: PloS one 20120101
Title: DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma.
Journal: PloS one 20120101
Title: Metronomic chemotherapy with the COMBAT regimen in advanced pediatric malignancies: a multicenter experience.
Journal: Oncology 20120101
Title: Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.
Journal: PloS one 20120101
Title: Cellular host responses to gliomas.
Journal: PloS one 20120101
Title: Effect of angiogenesis inhibitor bevacizumab on survival in patients with cancer: a meta-analysis of the published literature.
Journal: PloS one 20120101
Title: Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update.
Journal: TheScientificWorldJournal 20120101
Title: Long-term survival after gamma knife radiosurgery in a case of recurrent glioblastoma multiforme: a case report and review of the literature.
Journal: Case reports in medicine 20120101
Title: Desmoplastic small round cell tumor: current management and recent findings.
Journal: Sarcoma 20120101
Title: Methotrexate induced lung injury in a patient with primary CNS lymphoma: a case report.
Journal: Mediterranean journal of hematology and infectious diseases 20120101
Title: Identification of t(1;19)(q12;p13) and ploidy changes in an ependymosarcoma: a cytogenetic evaluation.
Journal: Clinical neuropathology 20120101
Title: The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Journal: PloS one 20120101
Title: Solitary fibrous tumors and so-called hemangiopericytoma.
Journal: Sarcoma 20120101
Title: Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-κB and upregulation of IL-1Ra in melanoma model.
Journal: PloS one 20120101
Title: Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells.
Journal: PloS one 20120101
Title: The role of radiation therapy in the management of metastatic melanoma in the brain.
Journal: International journal of surgical oncology 20120101
Title: A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy.
Journal: Journal of translational medicine 20120101
Title: Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion.
Journal: Molecular cancer 20120101
Title: The social environment and neurogenesis in the adult Mammalian brain.
Journal: Frontiers in human neuroscience 20120101
Title: Paratesticular desmoplastic small round cell tumour: an unusual tumour with an unusual fusion; cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH.
Journal: Clinical sarcoma research 20120101
Title: Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment.
Journal: Clinical sarcoma research 20120101
Title: Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours.
Journal: Clinical sarcoma research 20120101
Title: Prognostic significance of concomitant radiotherapy in newly diagnosed glioblastoma multiforme: a multivariate analysis of 116 patients.
Journal: Annals of Saudi medicine 20120101
Title: GABA-A channel subunit expression in human glioma correlates with tumor histology and clinical outcome.
Journal: PloS one 20120101
Title: Identification of novel human damage response proteins targeted through yeast orthology.
Journal: PloS one 20120101
Title: Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles.
Journal: International journal of nanomedicine 20120101
Title: Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival.
Journal: PloS one 20120101
Title: Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model.
Journal: PloS one 20120101
Title: Recent medical management of glioblastoma.
Journal: Advances in experimental medicine and biology 20120101
Title: Primary glioblastoma multiforme of medulla oblongata: Case report and review of literature.
Journal: Asian journal of neurosurgery 20120101
Title: Template-cut: a pattern-based segmentation paradigm.
Journal: Scientific reports 20120101
Title: Methylation-mediated molecular dysregulation in clinical oral malignancy.
Journal: Journal of oncology 20120101
Title: Radiotherapy and erlotinib combined: review of the preclinical and clinical evidence.
Journal: Frontiers in oncology 20120101
Title: The genomic and proteomic content of cancer cell-derived exosomes.
Journal: Frontiers in oncology 20120101
Title: Current and emerging pharmacotherapies for primary CNS lymphoma.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Preoperative FDG-PET/CT Is an Important Tool in the Management of Patients with Thick (T4) Melanoma.
Journal: Dermatology research and practice 20120101
Title: Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.
Journal: PloS one 20120101
Title: Therapeutic strategies based on polymeric microparticles.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Melanoma chemotherapy leads to the selection of ABCB5-expressing cells.
Journal: PloS one 20120101
Title: Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.
Journal: Anemia 20120101
Title: Doxorubicin-mediated radiosensitivity in multicellular spheroids from a lung cancer cell line is enhanced by composite micelle encapsulation.
Journal: International journal of nanomedicine 20120101
Title: The synergistic effects of DNA-targeted chemotherapeutics and histone deacetylase inhibitors as therapeutic strategies for cancer treatment.
Journal: Current medicinal chemistry 20120101
Title: Nucleic acids in human glioma treatment: innovative approaches and recent results.
Journal: Journal of signal transduction 20120101
Title: Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Metformin: an emerging new therapeutic option for targeting cancer stem cells and metastasis.
Journal: Journal of oncology 20120101
Title: EGFR inhibition in glioma cells modulates Rho signaling to inhibit cell motility and invasion and cooperates with temozolomide to reduce cell growth.
Journal: PloS one 20120101
Title: Long term experience in high grade glial tumors with temozolomide.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20120101
Title: Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells.
Journal: PloS one 20120101
Title: Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Sensitization of glioma cells by X-linked inhibitor of apoptosis protein knockdown.
Journal: Oncology 20120101
Title: Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistant.
Journal: PloS one 20120101
Title: Beyond Genetics in Glioma Pathways: The Ever-Increasing Crosstalk between Epigenomic and Genomic Events.
Journal: Journal of signal transduction 20120101
Title: Strategies to improve the killing of tumors using temozolomide: targeting the DNA repair protein MGMT.
Journal: Current medicinal chemistry 20120101
Title: Active home-based cancer treatment.
Journal: Journal of multidisciplinary healthcare 20120101
Title: Immunosignaturing can detect products from molecular markers in brain cancer.
Journal: PloS one 20120101
Title: Temozolomide combined with radiotherapy in the treatment of recurrent cranial meningioma previously treated with multiple surgical resections and two sessions of radiosurgery: a case report and literature review.
Journal: Tumori 20120101
Title: Radiosurgery for high-grade glioma.
Journal: Surgical neurology international 20120101
Title: O6-Methylguanine-methyltransferase (MGMT) promoter methylation status in glioma stem-like cells is correlated to temozolomide sensitivity under differentiation-promoting conditions.
Journal: International journal of molecular sciences 20120101
Title: Interdisciplinary treatment of glioblastoma: analysis of prognostic factors and treatment results in unselected patients.
Journal: Neoplasma 20120101
Title: Stem cell based glioblastoma gene therapy.
Journal: Neoplasma 20120101
Title: Novel nonclassical antifolate, 2-[N-(2´-Hydroxyethyl)amino]methyl-3H-quinazolin-4-one, with a potent antineoplastic activity toward leukemia cells.
Journal: Neoplasma 20120101
Title: [Temodal--an alkylating cytostatic agent. Effectiveness in patients with malignant gliomas].
Journal: Voprosy onkologii 20120101
Title: The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels.
Journal: The Journal of international medical research 20120101
Title: Combining stereotactic radiosurgery and systemic therapy for brain metastases: a potential role for temozolomide.
Journal: Frontiers in oncology 20120101
Title: The strategy for enhancing temozolomide against malignant glioma.
Journal: Frontiers in oncology 20120101
Title: [Treatment for volume upgrading of the low-grade supratentorial glioma after the subtotal neurosurgical resection].
Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20120101
Title: Anaplastic ganglioglioma: a very rare intramedullary spinal cord tumor.
Journal: Pediatric neurosurgery 20120101
Title: Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
Journal: PloS one 20120101
Title: Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics.
Journal: Journal of oncology 20120101
Title: Temozolomide as second or third line treatment of patients with neuroendocrine carcinomas.
Journal: TheScientificWorldJournal 20120101
Title: Fasting enhances the response of glioma to chemo- and radiotherapy.
Journal: PloS one 20120101
Title: Survival over 6 years in a patient with brain metastases from melanoma treated with temozolomide.
Journal: BMJ case reports 20120101
Title: A simplified approach for the molecular classification of glioblastomas.
Journal: PloS one 20120101
Title: Long-term survival in metastatic malignant melanoma: ipilimumab followed by vemurafenib in a patient with brain metastasis.
Journal: Internal medicine (Tokyo, Japan) 20120101
Title: Stereotactic intracranial implantation and in vivo bioluminescent imaging of tumor xenografts in a mouse model system of glioblastoma multiforme.
Journal: Journal of visualized experiments : JoVE 20120101
Title: Management of cytomegalovirus infection in a patient with malignant glioma treated with temozolomide and steroids.
Journal: Internal medicine (Tokyo, Japan) 20120101
Title: Clinical neuropathology practice guide 06-2012: MGMT testing in elderly glioblastoma patients--yes, but how?
Journal: Clinical neuropathology 20120101
Title: Hypofractionated Radiotherapy and Stereotactic Boost with Concurrent and Adjuvant Temozolamide for Glioblastoma in Good Performance Status Elderly Patients - Early Results of a Phase II Trial.
Journal: Frontiers in oncology 20120101
Title: A case of nonfunctioning pituitary carcinoma that responded to temozolomide treatment.
Journal: Case reports in endocrinology 20120101
Title: Angiogenic potential of the cerebrospinal fluid (CSF) of patients with high-grade gliomas measured with the chick embryo chorioallantoic membrane assay (CAM).
Journal: Biological research 20120101
Title: Rapid desensitization with temozolomide in patients with delayed maculopapular rash.
Journal: Journal of investigational allergology & clinical immunology 20120101
Title: Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells.
Journal: PloS one 20120101
Title: Polifeprosan 20, 3.85% carmustine slow-release wafer in malignant glioma: evidence for role in era of standard adjuvant temozolomide.
Journal: Core evidence 20120101
Title: Integrins and p53 pathways in glioblastoma resistance to temozolomide.
Journal: Frontiers in oncology 20120101
Title: Noscapine inhibits tumor growth in TMZ-resistant gliomas.
Journal: Cancer letters 20111222
Title: Predicting the myelotoxicity of chemotherapy: the use of pretreatment O6-methylguanine-DNA methyltransferase determination in peripheral blood mononuclear cells.
Journal: Melanoma research 20111201
Title: Temozolomide (Temodar®) and capecitabine (Xeloda®) treatment of an aggressive corticotroph pituitary tumor.
Journal: Pituitary 20111201
Title: Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C.
Journal: Investigational new drugs 20111201
Title: A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20111201
Title: MGMT immunoexpression in adamantinomatous craniopharyngiomas.
Journal: Pituitary 20111201
Title: Grand rounds at the National Institutes of Health: HDAC inhibitors as radiation modifiers, from bench to clinic.
Journal: Journal of cellular and molecular medicine 20111201
Title: The status of Tsukuba BNCT trial: BPA-based boron neutron capture therapy combined with X-ray irradiation.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20111201
Title: Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20111201
Title: Primary CNS lymphoma other than DLBCL: a descriptive analysis of clinical features and treatment outcomes.
Journal: Annals of hematology 20111201
Title: Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: an assessment of clinical potential.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20111201
Title: Primary gliosarcoma--clinical experience from a regional cancer centre in north India.
Journal: British journal of neurosurgery 20111201
Title: Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide.
Journal: Journal of neuro-oncology 20111201
Title: A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma.
Journal: Journal of neuro-oncology 20111201
Title: O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry.
Journal: Biochimica et biophysica acta 20111201
Title: Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
Journal: Neuro-oncology 20111201
Title: Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma.
Journal: Journal of neurosurgery 20111201
Title: Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
Journal: Journal of neurosurgery 20111201
Title: MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis.
Journal: Stem cells (Dayton, Ohio) 20111201
Title: Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease?
Journal: Journal of pediatric hematology/oncology 20111201
Title: Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation.
Journal: Nature 20111201
Title: Towards personalized therapy for patients with glioblastoma.
Journal: Expert review of anticancer therapy 20111201
Title: Prognostic impact of hemoglobin level and other factors in patients with high-grade gliomas treated with postoperative radiochemotherapy and sequential chemotherapy based on temozolomide: a 10-year experience at a single institution.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20111201
Title: Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis.
Journal: Journal of medical imaging and radiation oncology 20111201
Title: Pilot study of a pediatric metronomic 4-drug regimen.
Journal: Oncotarget 20111201
Title: Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma.
Journal: Cell death & disease 20111201
Title: PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation.
Journal: Oncotarget 20111201
Title: IL-13Rα2-Targeted Therapy Escapees: Biologic and Therapeutic Implications.
Journal: Translational oncology 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide.
Journal: Anticancer research 20111201
Title: Expression of EGFRvIII in glioblastoma: prognostic significance revisited.
Journal: Neoplasia (New York, N.Y.) 20111201
Title: Galectin-1 as an oncotarget in gliomas and melanomas.
Journal: Oncotarget 20111201
Title: Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies.
Journal: Genes & cancer 20111201
Title: [Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20111123
Title: Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20111115
Title: A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111115
Title: Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control.
Journal: Cancer research 20111115
Title: Veliparib plus temozolomide in metastatic melanoma trends toward increased PFS but results are not statistically significant.
Journal: Oncology (Williston Park, N.Y.) 20111115
Title: HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A.
Journal: International journal of cancer 20111101
Title: Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?
Journal: British journal of pharmacology 20111101
Title: Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor.
Journal: Cancer 20111101
Title: Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic.
Journal: Journal of neuro-oncology 20111101
Title: Assessment of MGMT promoter methylation status in pleomorphic xanthoastrocytoma.
Journal: Journal of neuro-oncology 20111101
Title: Complete response induced by fotemustine given as single agent in a patient with primary central nervous system non-Hodgkin aggressive lymphoma relapsed after high-dose chemotherapy and autologous stem cell support.
Journal: Leukemia & lymphoma 20111101
Title: Leptomeningeal melanomatosis: stabilization of disease due to radiation, temozolomide and intrathecal liposomal cytarabine.
Journal: Acta oncologica (Stockholm, Sweden) 20111101
Title: Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity.
Journal: Journal of neuro-oncology 20111101
Title: MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20111101
Title: Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20111101
Title: A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Journal: Acta neuropathologica 20111101
Title: Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways.
Journal: Oncology reports 20111101
Title: Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs.
Journal: Chemistry and physics of lipids 20111101
Title: Conditional probability of survival in patients with newly diagnosed glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111101
Title: Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101
Title: Rechallenge with temozolomide in recurrent glioma.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101
Title: Lecture: fotemustine in brain tumors.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101
Title: Infections in neuro-oncology.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101
Title: Combination therapy with rituximab and temozolomide for recurrent and refractory primary central nervous system lymphoma.
Journal: Yonsei medical journal 20111101
Title: Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20111101
Title: Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells.
Journal: Oncotarget 20111101
Title: The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy.
Journal: Therapeutic advances in medical oncology 20111101
Title: Cell death forms and HSP70 expression in U87 cells after ionizing radiation and/or chemotherapy.
Journal: Anticancer research 20111101
Title: Prolonged administration of temozolomide in adult patients with anaplastic glioma.
Journal: Anticancer research 20111101
Title: [Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20111101
Title: De novo aneurysm after treatment of glioblastoma.
Journal: Journal of Korean Neurosurgical Society 20111101
Title: [Clinical trial updates for malignant brain tumors].
Journal: Rinsho shinkeigaku = Clinical neurology 20111101
Title: Secondary gliosarcoma after the treatment of primary glioblastoma multiforme.
Journal: North American journal of medical sciences 20111101
Title: A rare case of an aldosterone secreting metastatic adrenocortical carcinoma and papillary thyroid carcinoma in a 31-year-old male.
Journal: Rare tumors 20111021
Title: Clinical effect of temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy.
Journal: Cancer 20111015
Title: Poly(methyl malate) nanoparticles: formation, degradation, and encapsulation of anticancer drugs.
Journal: Macromolecular bioscience 20111010
Title: North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20111001
Title: Induction of autophagy in temozolomide treated malignant gliomas.
Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20111001
Title: Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.
Journal: Annals of surgical oncology 20111001
Title: Aggressive pituitary tumours: the role of temozolomide and the assessment of MGMT status.
Journal: European journal of clinical investigation 20111001
Title: Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer.
Journal: The Journal of investigative dermatology 20111001
Title: Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma.
Journal: Biomaterials 20111001
Title: Temozolomide decreases invasion of glioma stem cells by down-regulating TGF-β2.
Journal: Oncology reports 20111001
Title: Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma.
Journal: Cancer chemotherapy and pharmacology 20111001
Title: RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo.
Journal: Neuro-oncology 20111001
Title: MGMT immunoexpression in growth hormone-secreting pituitary adenomas and its correlation with Ki-67 labeling index and cytokeratin distribution pattern.
Journal: Endocrine 20111001
Title: Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?
Journal: Neuro-oncology 20111001
Title: Advances in tenascin-C biology.
Journal: Cellular and molecular life sciences : CMLS 20111001
Title: Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma.
Journal: Acta neuropathologica 20111001
Title: [Glioblastoma in the elderly].
Journal: Revue neurologique 20111001
Title: Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111001
Title: Down-regulation of EGFR prolonged cell growth of glioma but did not increase the sensitivity to temozolomide.
Journal: Anticancer research 20111001
Title: Primary central nervous system lymphoma presenting as Parinaud syndrome.
Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20111001
Title: American Society of Clinical Oncology 2011 CNS tumors update.
Journal: Expert review of anticancer therapy 20111001
Title: Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma.
Journal: Clinics (Sao Paulo, Brazil) 20111001
Title: Pediatric suprasellar lesions.
Journal: Journal of pediatric neurosciences 20111001
Title: Management of posterior fossa gliomas in children.
Journal: Journal of pediatric neurosciences 20111001
Title: Is neurodegenerative disease a long-latency response to early-life genotoxin exposure?
Journal: International journal of environmental research and public health 20111001
Title: Early-stage progress on glioma vaccines.
Journal: Journal of the National Cancer Institute 20110921
Title: Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110920
Title: Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
Journal: Neurology 20110920
Title: Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
Journal: Blood 20110915
Title: Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats.
Journal: Medical oncology (Northwood, London, England) 20110901
Title: Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.
Journal: International journal of radiation oncology, biology, physics 20110901
Title: Genetic variations in VEGF and VEGFR2 and glioblastoma outcome.
Journal: Journal of neuro-oncology 20110901
Title: Dural venous sinus thrombosis in anaplastic astrocytoma following concurrent temozolomide and focal brain radiotherapy plus bevacizumab.
Journal: Journal of neuro-oncology 20110901
Title: Combined chemotherapy with temozolomide and fotemustine in recurrent glioblastoma patients.
Journal: Journal of neuro-oncology 20110901
Title: Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging.
Journal: Journal of neuro-oncology 20110901
Title: MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas.
Journal: Journal of neuro-oncology 20110901
Title: Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110901
Title: A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.
Journal: Journal of neuro-oncology 20110901
Title: Leptomeningeal disease in oligodendroglial tumors: a population-based study.
Journal: Journal of neuro-oncology 20110901
Title: Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).
Journal: Journal of neuro-oncology 20110901
Title: Treatment of pituitary neoplasms with temozolomide: A review.
Journal: Cancer 20110901
Title: Tissue concentration of systemically administered antineoplastic agents in human brain tumors.
Journal: Journal of neuro-oncology 20110901
Title: Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review.
Journal: Journal of neuro-oncology 20110901
Title: Temozolomide may induce therapy-related acute lymphoblastic leukaemia.
Journal: British journal of haematology 20110901
Title: Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress.
Journal: Angiogenesis 20110901
Title: Effect of temozolomide on cell viability in gonadotroph adenoma cell lines.
Journal: Oncology reports 20110901
Title: Treatment of glioblastoma in 'elderly' patients.
Journal: Current treatment options in oncology 20110901
Title: YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.
Journal: International journal of cancer 20110901
Title: Multicenter phase II trial of temozolomide in mycosis fungoides/sezary syndrome: correlation with O⁶-methylguanine-DNA methyltransferase and mismatch repair proteins.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110901
Title: The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival.
Journal: Neurological research 20110901
Title: Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas.
Journal: International journal of oncology 20110901
Title: Antitumor compound testing in glioblastoma organotypic brain cultures.
Journal: Journal of biomolecular screening 20110901
Title: In regard McDonald et al., to Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma (Int J Radiat Oncol Biol Phys 2011;79:130-136).
Journal: International journal of radiation oncology, biology, physics 20110901
Title: Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20110901
Title: Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.
Journal: Cell death & disease 20110901
Title: Second primary glioblastoma multiforme following autologous hematopoietic stem cell transplantation in a patient with acute myelogenous leukemia.
Journal: Cancer research and treatment : official journal of Korean Cancer Association 20110901
Title: Temozolomide induced liver injury.
Journal: Acta neurologica Belgica 20110901
Title: [Safety and efficacy of three-dimensional conformal radiotherapy combined with temozolomide in treatment of diffuse brainstem gliomas].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110901
Title: 3-D conformal radiotherapy with concomitant and adjuvant temozolomide for patients with glioblastoma multiforme and evaluation of prognostic factors.
Journal: Radiology and oncology 20110901
Title: Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110815
Title: Rare phenomenon: liver metastases from glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810
Title: Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy.
Journal: Journal of neuro-oncology 20110801
Title: Longitudinal MRI evidence for decreased survival among periventricular glioblastoma.
Journal: Journal of neuro-oncology 20110801
Title: Cisplatin and temozolomide combination in the treatment of leptomeningeal carcinomatosis from ethmoid sinus intestinal-type adenocarcinoma.
Journal: Journal of neuro-oncology 20110801
Title: Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.
Journal: Journal of neuro-oncology 20110801
Title: Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide.
Journal: Journal of neuro-oncology 20110801
Title: Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
Journal: Journal of neuro-oncology 20110801
Title: The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.
Journal: British journal of neurosurgery 20110801
Title: Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
Journal: International journal of cancer 20110801
Title: Complete remission of recurrent and refractory uterine epithelioid leiomyosarcoma using weekly administration of bevacizumab and temozolomide.
Journal: European journal of obstetrics, gynecology, and reproductive biology 20110801
Title: Primary brain tumors in the elderly population.
Journal: Current treatment options in neurology 20110801
Title: High-grade gliomas.
Journal: Current treatment options in neurology 20110801
Title: Combined use of anticancer drugs and an inhibitor of multiple drug resistance-associated protein-1 increases sensitivity and decreases survival of glioblastoma multiforme cells in vitro.
Journal: Neurochemical research 20110801
Title: Treatment outcomes for patients with glioblastoma multiforme and a low Karnofsky Performance Scale score on presentation to a tertiary care institution. Clinical article.
Journal: Journal of neurosurgery 20110801
Title: Seizure control: a secondary benefit of chemotherapeutic temozolomide in brain cancer patients.
Journal: Epilepsy research 20110801
Title: Immunotherapy for glioblastoma: the devil is in the details.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110801
Title: Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110801
Title: A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.
Journal: Neuro-oncology 20110801
Title: Determination of temozolomide in serum and brain tumor with micellar electrokinetic capillary chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110801
Title: Towards tailored therapy of glioblastoma multiforme.
Journal: Journal of chemotherapy (Florence, Italy) 20110801
Title: Mouse models to interrogate the implications of the differentiation status in the ontogeny of gliomas.
Journal: Oncotarget 20110801
Title: The NFκB pathway: a therapeutic target in glioblastoma.
Journal: Oncotarget 20110801
Title: Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines.
Journal: British journal of cancer 20110726
Title: Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.
Journal: The Journal of biological chemistry 20110722
Title: Engineering the brain tumor microenvironment enhances the efficacy of dendritic cell vaccination: implications for clinical trial design.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110715
Title: Response to radiation in renal medullary carcinoma.
Journal: Rare tumors 20110711
Title: Enhancing adherence to capecitabine chemotherapy by means of multidisciplinary pharmaceutical care.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110701
Title: Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study.
Journal: Journal of neuro-oncology 20110701
Title: Efficacy of protracted dose-dense temozolomide in patients with recurrent high-grade glioma.
Journal: Journal of neuro-oncology 20110701
Title: Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
Journal: Journal of neuro-oncology 20110701
Title: Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma.
Journal: Journal of neuro-oncology 20110701
Title: Radiotherapy followed by adjuvant temozolomide with or without neoadjuvant ACNU-CDDP chemotherapy in newly diagnosed glioblastomas: a prospective randomized controlled multicenter phase III trial.
Journal: Journal of neuro-oncology 20110701
Title: PI3Kinase signaling in glioblastoma.
Journal: Journal of neuro-oncology 20110701
Title: Therapeutic strategies for advanced neuroendocrine carcinomas of jejunum/ileum and pancreatic origin.
Journal: Gut 20110701
Title: Therapy of aggressive pituitary tumors.
Journal: Expert opinion on pharmacotherapy 20110701
Title: MGMT promoter methylation and temozolomide response in choroid plexus carcinoma.
Journal: Brain tumor pathology 20110701
Title: Eckol suppresses maintenance of stemness and malignancies in glioma stem-like cells.
Journal: Toxicology and applied pharmacology 20110701
Title: Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera?
Journal: Expert opinion on investigational drugs 20110701
Title: Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275.
Journal: Anti-cancer drugs 20110701
Title: Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032).
Journal: European journal of cancer (Oxford, England : 1990) 20110701
Title: Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110701
Title: Glioblastoma: patterns of recurrence and efficacy of salvage treatments.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20110701
Title: Melanoma-associated retinopathy: a presenting sign of metastatic disease.
Journal: Journal of the American Academy of Dermatology 20110701
Title: Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
Journal: Nature medicine 20110701
Title: Pancreatic endocrine tumors: a report on a patient treated with sorafenib.
Journal: Journal of Korean medical science 20110701
Title: A case of intracranial malignant fibrous histiocytoma.
Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701
Title: Advances in malignant glioma drug discovery.
Journal: Expert opinion on drug discovery 20110701
Title: Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid.
Journal: Cancer research 20110615
Title: The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110615
Title: How fine a slice: treatment of newly diagnosed glioblastoma with an epidermal growth factor receptor variant III peptide vaccine.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110610
Title: Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas.
Journal: British journal of cancer 20110607
Title: Implementation of neuro-oncology service reconfiguration in accordance with NICE guidance provides enhanced clinical care for patients with glioblastoma multiforme.
Journal: British journal of cancer 20110607
Title: Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
Journal: British journal of cancer 20110607
Title: Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens.
Journal: British journal of cancer 20110607
Title: Delayed repair of radiation induced clustered DNA damage: friend or foe?
Journal: Mutation research 20110603
Title: Genomic aberrations associated with outcome in anaplastic oligodendroglial tumors treated within the EORTC phase III trial 26951.
Journal: Journal of neuro-oncology 20110601
Title: Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
Journal: Journal of neuro-oncology 20110601
Title: Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells.
Journal: Journal of neuro-oncology 20110601
Title: Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme.
Journal: Journal of neuro-oncology 20110601
Title: Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.
Journal: Journal of neuro-oncology 20110601
Title: Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
Journal: Journal of neuro-oncology 20110601
Title: Quantitative analysis of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas.
Journal: Journal of neuro-oncology 20110601
Title: Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA.
Journal: Journal of neuro-oncology 20110601
Title: Testing new regimens in patients with advanced soft tissue sarcoma: analysis of publications from the last 10 years.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110601
Title: Advances in MRI assessment of gliomas and response to anti-VEGF therapy.
Journal: Current neurology and neuroscience reports 20110601
Title: Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas.
Journal: Journal of neurosurgery 20110601
Title: Treatment of glioblastoma multiforme with radiotherapy and concomitant and adjuvant temozolomide: translation of randomised controlled trial evidence into routine clinical practice.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20110601
Title: DNA repair: the culprit for tumor-initiating cell survival?
Journal: Cancer metastasis reviews 20110601
Title: SMART syndrome: a late reversible complication after radiation therapy for brain tumours.
Journal: Journal of neurology 20110601
Title: A mechanism of acquiring temozolomide resistance during transformation of atypical prolactinoma into prolactin-producing pituitary carcinoma: case report.
Journal: Neurosurgery 20110601
Title: [Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma].
Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20110601
Title: The insulin-like growth factor-I receptor kinase inhibitor NVP-ADW742 sensitizes medulloblastoma to the effects of chemotherapy.
Journal: Oncology reports 20110601
Title: Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens: DNA damage accumulation contribution.
Journal: Melanoma research 20110601
Title: Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
Journal: Acta neurochirurgica 20110601
Title: A retrospective survey of patients with malignant gliomas treated in the neuro-oncological care system under the Universal National Health Insurance program in Taiwan.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110601
Title: Temozolomide and pituitary adenoma.
Journal: Journal of neurosurgery 20110601
Title: Management of cutaneous metastases using electrochemotherapy.
Journal: Acta oncologica (Stockholm, Sweden) 20110601
Title: Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study.
Journal: Wiener klinische Wochenschrift 20110601
Title: Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
Journal: Journal of magnetic resonance imaging : JMRI 20110601
Title: Successful desensitization with temozolomide.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20110601
Title: Glioblastoma multiforme: enhancing survival and quality of life.
Journal: Clinical journal of oncology nursing 20110601
Title: JLK1486, a Bis 8-Hydroxyquinoline-Substituted Benzylamine, Displays Cytostatic Effects in Experimental Gliomas through MyT1 and STAT1 Activation and, to a Lesser Extent, PPARγ Activation.
Journal: Translational oncology 20110601
Title: Pathway inhibition: emerging molecular targets for treating glioblastoma.
Journal: Neuro-oncology 20110601
Title: International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.
Journal: Neuro-oncology 20110601
Title: Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors.
Journal: Current medicinal chemistry 20110601
Title: Trimodal glioblastoma treatment consisting of concurrent radiotherapy, temozolomide, and the novel TGF-β receptor I kinase inhibitor LY2109761.
Journal: Neoplasia (New York, N.Y.) 20110601
Title: [Cutaneous neutrophils infiltrates. Case 4. Pseudo-tumoral cutaneous alternariosis].
Journal: Annales de pathologie 20110601
Title: Development of glioblastoma cell lines expressing red fluorescence for non-invasive live imaging of intracranial tumors.
Journal: Anticancer research 20110601
Title: [Problems of chemotherapy for glioma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20110601
Title: Metabolism and brain cancer.
Journal: Clinics (Sao Paulo, Brazil) 20110601
Title: Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part.
Journal: British journal of cancer 20110524
Title: Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20110524
Title: Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110515
Title: Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110515
Title: KS900: A hypoxia-directed, reductively activated methylating antitumor prodrug that selectively ablates O(6)-alkylguanine-DNA alkyltransferase in neoplastic cells.
Journal: Biochemical pharmacology 20110515
Title: Annual report to the nation on the status of cancer, 1975-2007, featuring tumors of the brain and other nervous system.
Journal: Journal of the National Cancer Institute 20110504
Title: Palonosetron for the prevention of chemotherapy-induced nausea and vomiting in glioblastoma patients treated with temozolomide: a phase II study.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110501
Title: Prognostic value of early [18F]fluoroethyltyrosine positron emission tomography after radiochemotherapy in glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20110501
Title: A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.
Journal: Journal of neuro-oncology 20110501
Title: Hepatic encephalopathy after treatment with temozolomide.
Journal: Journal of neuro-oncology 20110501
Title: Feasibility study of 21-day-on/7-day-off temozolomide in children with brain tumors.
Journal: Journal of neuro-oncology 20110501
Title: Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
Journal: Journal of neuro-oncology 20110501
Title: Treatment of follicular non-Hodgkin's lymphoma with or without rituximab: cost-effectiveness and value of information based on a 5-year follow-up.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110501
Title: Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.
Journal: European journal of clinical investigation 20110501
Title: Dopamine agonist-resistant prolactinomas.
Journal: Journal of neurosurgery 20110501
Title: The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.
Journal: European journal of cancer (Oxford, England : 1990) 20110501
Title: A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.
Journal: Acta neuropathologica 20110501
Title: Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells.
Journal: Neuro-oncology 20110501
Title: N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
Journal: Neuro-oncology 20110501
Title: Temozolomide-induced modification of the CXC chemokine network in experimental gliomas.
Journal: International journal of oncology 20110501
Title: Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.
Journal: International journal of radiation biology 20110501
Title: An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting.
Journal: Cancer chemotherapy and pharmacology 20110501
Title: Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110501
Title: Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20110501
Title: Considering temozolomide as a novel potential treatment for esophageal cancer.
Journal: Cancer 20110501
Title: PARP inhibitors stumble in breast cancer.
Journal: Nature biotechnology 20110501
Title: NRAS-mutant melanoma: response to chemotherapy.
Journal: Archives of dermatology 20110501
Title: The effect of PTEN on proliferation and drug-, and radiosensitivity in malignant glioma cells.
Journal: Anticancer research 20110501
Title: [News on melanoma from the 2010 Dermatology Days in Paris].
Journal: Annales de dermatologie et de venereologie 20110501
Title: Early toxicity predicts long-term survival in high-grade glioma.
Journal: British journal of cancer 20110426
Title: Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
Journal: Cancer 20110415
Title: Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110415
Title: A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme.
Journal: Journal of neuro-oncology 20110401
Title: Determination of the methylation status of MGMT in different regions within glioblastoma multiforme.
Journal: Journal of neuro-oncology 20110401
Title: Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma.
Journal: Journal of neuro-oncology 20110401
Title: Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma.
Journal: Journal of neuro-oncology 20110401
Title: Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.
Journal: Journal of neuro-oncology 20110401
Title: Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells.
Journal: Journal of cellular physiology 20110401
Title: Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide.
Journal: Journal of neurology, neurosurgery, and psychiatry 20110401
Title: Temozolomide-based dry powder formulations for lung tumor-related inhalation treatment.
Journal: Pharmaceutical research 20110401
Title: The combi-targeting concept: mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle.
Journal: Cellular signalling 20110401
Title: Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.
Journal: Biomaterials 20110401
Title: Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110401
Title: Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
Journal: Neuro-oncology 20110401
Title: O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.
Journal: Brain tumor pathology 20110401
Title: Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.
Journal: Neuro-oncology 20110401
Title: Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group.
Journal: Neuro-oncology 20110401
Title: The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110401
Title: AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.
Journal: Advances in therapy 20110401
Title: Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo.
Journal: Translational oncology 20110401
Title: Factors influencing the response to high dose methotrexate-based vincristine and procarbazine combination chemotherapy for primary central nervous system lymphoma.
Journal: Journal of Korean medical science 20110401
Title: Glioblastoma: changing expectations?
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20110401
Title: Response to nimotuzumab in a child with a progressive diffuse intrinsic pontine glioma.
Journal: Pediatrics international : official journal of the Japan Pediatric Society 20110401
Title: Atypical teratoid/rhabdoid tumors in adults: a case report and treatment-focused review.
Journal: Journal of clinical medicine research 20110401
Title: Spinal intradural extraosseous Ewing's sarcoma.
Journal: Rare tumors 20110330
Title: Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
Journal: Neurology 20110329
Title: Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
Journal: Cancer letters 20110328
Title: A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.
Journal: Biochemical and biophysical research communications 20110318
Title: Chemotherapy wafers for high grade glioma.
Journal: The Cochrane database of systematic reviews 20110316
Title: Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.
Journal: Cancer research 20110315
Title: Dichloroacetate metabolically targeted therapy defeats cytotoxicity of standard anticancer drugs.
Journal: Cancer chemotherapy and pharmacology 20110301
Title: Factors involved in maintaining prolonged functional independence following supratentorial glioblastoma resection. Clinical article.
Journal: Journal of neurosurgery 20110301
Title: Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
Journal: Journal of neuro-oncology 20110301
Title: Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.
Journal: Journal of neuro-oncology 20110301
Title: Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article.
Journal: Journal of neurosurgery 20110301
Title: Temozolomide for corticotroph pituitary adenomas refractory to standard therapy.
Journal: Pituitary 20110301
Title: High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan.
Journal: Pediatric blood & cancer 20110301
Title: Advances in translational research in neuro-oncology.
Journal: Archives of neurology 20110301
Title: Bevacizumab and irinotecan in the treatment of children with recurrent/refractory medulloblastoma.
Journal: Pediatric blood & cancer 20110301
Title: Advances in translational research provide a rationale for clinical re-evaluation of high-dose radiotherapy for glioblastoma.
Journal: Medical hypotheses 20110301
Title: Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
Journal: Neuro-oncology 20110301
Title: Use of Bevacizumab for neurological complications during initial treatment of malignant gliomas.
Journal: Neurologia (Barcelona, Spain) 20110301
Title: Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome.
Journal: Epigenetics 20110301
Title: Targeted delivery of chlorotoxin-modified DNA-loaded nanoparticles to glioma via intravenous administration.
Journal: Biomaterials 20110301
Title: Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: a case collection study.
Journal: Acta neurochirurgica 20110301
Title: BTECH: a platform to integrate genomic, transcriptomic and epigenomic alterations in brain tumors.
Journal: Neuroinformatics 20110301
Title: Intramedullary PNET of the spine: long-term survival after combined modality therapy and subsequent relapse.
Journal: Journal of pediatric hematology/oncology 20110301
Title: MGMT is a molecular determinant for potency of the DNA-EGFR-combi-molecule ZRS1.
Journal: Molecular cancer research : MCR 20110301
Title: EGFR gene overexpression retained in an invasive xenograft model by solid orthotopic transplantation of human glioblastoma multiforme into nude mice.
Journal: Cancer investigation 20110301
Title: A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours.
Journal: British journal of cancer 20110301
Title: Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.
Journal: Neuro-oncology 20110301
Title: Controversies in the adjuvant therapy of high-grade gliomas.
Journal: The oncologist 20110301
Title: Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation.
Journal: Journal of molecular medicine (Berlin, Germany) 20110301
Title: Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.
Journal: Oncotarget 20110301
Title: Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies.
Journal: Future oncology (London, England) 20110301
Title: [MGMT analysis in gliomas].
Journal: Bulletin du cancer 20110301
Title: Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis.
Journal: Journal of neurosurgical sciences 20110301
Title: Vascular co-option in lung cancer metastatic to the eye after treatment with bevacizumab.
Journal: Journal of ophthalmic inflammation and infection 20110301
Title: [A case of primary diffuse leptomeningeal gliomatosis, clinically indistinguishable from metastatic meningeal carcinomatosis].
Journal: Rinsho shinkeigaku = Clinical neurology 20110301
Title: Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma.
Journal: Anticancer research 20110301
Title: [Nimotuzumab in combination with chemotherapy for patients with malignant gliomas].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110301
Title: [Pituitary carcinoma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110301
Title: Monitoring radiographic brain tumor progression.
Journal: Toxins 20110301
Title: STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy?
Journal: International journal of cancer 20110215
Title: Gene expression profiling of gliomas: merging genomic and histopathological classification for personalised therapy.
Journal: British journal of cancer 20110215
Title: Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines.
Journal: British journal of cancer 20110215
Title: Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.
Journal: Bioscience reports 20110201
Title: Temozolomide-induced inhibition of pituitary adenoma cells.
Journal: Journal of neurosurgery 20110201
Title: Up-front temozolomide in elderly patients with anaplastic oligodendroglioma and oligoastrocytoma.
Journal: Journal of neuro-oncology 20110201
Title: Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors.
Journal: Journal of neuro-oncology 20110201
Title: MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation.
Journal: Journal of neuro-oncology 20110201
Title: Treatment of pituitary neoplasms with temozolomide: a review.
Journal: Cancer 20110201
Title: siRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide.
Journal: The Journal of investigative dermatology 20110201
Title: Anti-tumour effects by a trimodal combination of temozolomide, meloxicam and X-rays in cultures of human glioma cells.
Journal: International journal of radiation biology 20110201
Title: Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.
Journal: Neuro-oncology 20110201
Title: Patient profiling for treatment toxicity: potential use of clinical and genomic factors.
Journal: Current oncology reports 20110201
Title: In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
Journal: Apoptosis : an international journal on programmed cell death 20110201
Title: Targeting BRAF for patients with melanoma.
Journal: British journal of cancer 20110201
Title: The correlation between promoter methylation status and the expression level of O6-methylguanine-DNA methyltransferase in recurrent glioma.
Journal: Japanese journal of clinical oncology 20110201
Title: First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
Journal: Neuro-oncology 20110201
Title: Case of atypical teratoid/rhabdoid tumor in an adult, with long survival.
Journal: Brain tumor pathology 20110201
Title: APO010, a synthetic hexameric CD95 ligand, induces human glioma cell death in vitro and in vivo.
Journal: Neuro-oncology 20110201
Title: The use and effectiveness of temozolomide in children with central nervous system tumours: a survey from the Canadian Paediatric Brain Tumour Consortium.
Journal: Current oncology (Toronto, Ont.) 20110201
Title: Bevacizumab as a treatment option for radiation-induced cerebral necrosis.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20110201
Title: Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts.
Journal: Cell death & disease 20110201
Title: The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis--a possible therapeutic target.
Journal: Oncotarget 20110201
Title: Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide.
Journal: Journal of medical imaging and radiation oncology 20110201
Title: Phase I trial of a personalized peptide vaccine for patients positive for human leukocyte antigen--A24 with recurrent or progressive glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110120
Title: First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.
Journal: Cancer 20110115
Title: Phase II study of irinotecan and temozolomide in children with relapsed or refractory neuroblastoma: a Children's Oncology Group study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110110
Title: Taming glioblastoma by targeting angiogenesis: 3 years later.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110110
Title: Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110110
Title: [Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship].
Journal: Zhonghua yi xue za zhi 20110104
Title: Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20110101
Title: Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma.
Journal: Journal of neuro-oncology 20110101
Title: Temozolomide for malignant primary spinal cord glioma: an experience of six cases and a literature review.
Journal: Journal of neuro-oncology 20110101
Title: Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.
Journal: Journal of neuro-oncology 20110101
Title: Trabectedin in the treatment of metastatic soft tissue sarcoma: cost-effectiveness, cost-utility and value of information.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110101
Title: Multiple primary cranio-spinal tumours in a 13-year-old female with neurofibromatosis type 2 management strategy.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101
Title: Supratentorial glioblastoma multiforme: the role of surgical resection versus biopsy among older patients.
Journal: Annals of surgical oncology 20110101
Title: A clinicopathological and molecular analysis of glioblastoma multiforme with long-term survival.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110101
Title: High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma.
Journal: European journal of cancer (Oxford, England : 1990) 20110101
Title: Temozolomide-induced severe myelosuppression: analysis of clinically associated polymorphisms in two patients.
Journal: Anti-cancer drugs 20110101
Title: Growth Inhibition and Induction of Apoptosis in SHG-44 Glioma Cells by Chinese Medicine Formula 'Pingliu Keli'.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient?
Journal: Acta neurochirurgica. Supplement 20110101
Title: Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion.
Journal: Neuro-oncology 20110101
Title: Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study.
Journal: Neuro-oncology 20110101
Title: Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
Journal: Neuro-oncology 20110101
Title: Down-regulation of O6-methylguanine-DNA methyl transferase enhances the effect of temozolomide in melanoma cells.
Journal: Medical hypotheses 20110101
Title: Targeted Therapy of Ewing's Sarcoma.
Journal: Sarcoma 20110101
Title: MGMT promoter methylation in pediatric high-grade gliomas.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101
Title: Radiographic patterns of relapse in glioblastoma.
Journal: Journal of neuro-oncology 20110101
Title: Evaluation of the anticancer activities of two fungal polycyclic ethanones, alternethanoxins A and B, and two of their derivatives.
Journal: International journal of oncology 20110101
Title: Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB.
Journal: International journal of oncology 20110101
Title: Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma.
Journal: Oncology reports 20110101
Title: Regional treatment strategies for in-transit melanoma metastasis.
Journal: Surgical oncology clinics of North America 20110101
Title: Current therapeutic approaches in metastatic and recurrent ewing sarcoma.
Journal: Sarcoma 20110101
Title: Transferrin-appended PEGylated nanoparticles for temozolomide delivery to brain: in vitro characterisation.
Journal: Journal of microencapsulation 20110101
Title: [Drug therapy of patients with recurrent glioblastoma: is there any evidence?].
Journal: Wiener medizinische Wochenschrift (1946) 20110101
Title: Targeting angiogenesis in childhood sarcomas.
Journal: Sarcoma 20110101
Title: Neurosurgical treatment of breast cancer metastases to the neurocranium.
Journal: Pathology research international 20110101
Title: Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors.
Journal: Journal of oncology 20110101
Title: Systematic review of medical treatment in melanoma: current status and future prospects.
Journal: The oncologist 20110101
Title: Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approaches.
Journal: Radiation oncology (London, England) 20110101
Title: A combined preclinical therapy of cannabinoids and temozolomide against glioma.
Journal: Molecular cancer therapeutics 20110101
Title: Anti-retinal pigment epithelium antibodies in acute exudative polymorphous vitelliform maculopathy: a new hypothesis about disease pathogenesis.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20110101
Title: INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival.
Journal: Pathology 20110101
Title: Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine.
Journal: Genome biology 20110101
Title: Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response.
Journal: Radiation oncology (London, England) 20110101
Title: Comprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBM.
Journal: PloS one 20110101
Title: Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma.
Journal: Sarcoma 20110101
Title: Blood-brain barrier integrity and breast cancer metastasis to the brain.
Journal: Pathology research international 20110101
Title: TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitro.
Journal: PloS one 20110101
Title: Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Journal: PloS one 20110101
Title: A novel SNP analysis method to detect copy number alterations with an unbiased reference signal directly from tumor samples.
Journal: BMC medical genomics 20110101
Title: O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.
Journal: BMC cancer 20110101
Title: Pathogenesis, diagnosis and management of primary melanoma of the colon.
Journal: World journal of surgical oncology 20110101
Title: Treatment of Parkinson's disease: nanostructured sol-gel silica-dopamine reservoirs for controlled drug release in the central nervous system.
Journal: International journal of nanomedicine 20110101
Title: Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.
Journal: PloS one 20110101
Title: A novel method for volumetric MRI response assessment of enhancing brain tumors.
Journal: PloS one 20110101
Title: DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer.
Journal: PloS one 20110101
Title: [Pseudoprogression or pseudoresponse: a challenge for the diagnostic imaging in Glioblastoma multiforme].
Journal: Wiener medizinische Wochenschrift (1946) 20110101
Title: Sodium ion channel mutations in glioblastoma patients correlate with shorter survival.
Journal: Molecular cancer 20110101
Title: GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
Journal: Methods in enzymology 20110101
Title: Pharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapy.
Journal: PloS one 20110101
Title: Xenotransplantation of mitochondrial electron transfer enzyme, Ndi1, in myocardial reperfusion injury.
Journal: PloS one 20110101
Title: Unfolded protein response in cancer: the physician's perspective.
Journal: Journal of hematology & oncology 20110101
Title: O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
Journal: PloS one 20110101
Title: Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression.
Journal: Cancer cell international 20110101
Title: Validation of the new Graded Prognostic Assessment scale for brain metastases: a multicenter prospective study.
Journal: Radiation oncology (London, England) 20110101
Title: EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: a potential mechanism of EGFR-driven antagonism of apoptosis.
Journal: Molecular cancer 20110101
Title: A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion.
Journal: PloS one 20110101
Title: Future perspectives in melanoma research. Meeting report from the 'Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010'.
Journal: Journal of translational medicine 20110101
Title: Radiation-induced astrocytoma with rapid malignant transformation: case report.
Journal: Neurologia medico-chirurgica 20110101
Title: Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles.
Journal: International journal of nanomedicine 20110101
Title: Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.
Journal: PloS one 20110101
Title: Quantitative model for efficient temporal targeting of tumor cells and neovasculature.
Journal: Computational and mathematical methods in medicine 20110101
Title: Computational modeling of tumor response to vascular-targeting therapies--part I: validation.
Journal: Computational and mathematical methods in medicine 20110101
Title: Combined treatment of uveal melanoma liver metastases.
Journal: European journal of medical research 20110101
Title: Differential analysis of glioblastoma multiforme proteome by a 2D-DIGE approach.
Journal: Proteome science 20110101
Title: An effective personalized approach to a rare tumor: prolonged survival in metastatic pancreatic acinar cell carcinoma based on genetic analysis and cell line development.
Journal: Journal of Cancer 20110101
Title: Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine.
Journal: BMC cancer 20110101
Title: Collagen triple helix repeat containing 1 promotes melanoma cell adhesion and survival.
Journal: Journal of cutaneous medicine and surgery 20110101
Title: A melanoma molecular disease model.
Journal: PloS one 20110101
Title: Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma.
Journal: PloS one 20110101
Title: O6 -methylguanine DNA methyltransferase gene promoter methylation in high-grade gliomas: a review of current status.
Journal: Neurology India 20110101
Title: Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme.
Journal: PloS one 20110101
Title: A ten-microRNA expression signature predicts survival in glioblastoma.
Journal: PloS one 20110101
Title: Stereocomplexes Formed From Select Oligomers of Polymer d-lactic Acid (PDLA) and l-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers-Applications of the Warburg Effect.
Journal: Perspectives in medicinal chemistry 20110101
Title: Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma.
Journal: Journal of neuroinflammation 20110101
Title: Tumor suppressor gene-based nanotherapy: from test tube to the clinic.
Journal: Journal of drug delivery 20110101
Title: Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures.
Journal: PloS one 20110101
Title: The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo.
Journal: Radiation oncology (London, England) 20110101
Title: Achievement of three year remission with bevacizumab and irinotecan in recurrent glioblastoma multiforme: a case report.
Journal: Clinical Medicine Insights. Oncology 20110101
Title: Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer.
Journal: Molecular cancer 20110101
Title: Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP.
Journal: Journal of hematology & oncology 20110101
Title: Camptothecin-based regimens for treatment of ewing sarcoma: past studies and future directions.
Journal: Sarcoma 20110101
Title: The validation of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30) in pre-operative patients with brain tumor in China.
Journal: BMC medical research methodology 20110101
Title: Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - .
Journal: Neurologia medico-chirurgica 20110101
Title: Delayed but Complete Response following Oral Temozolomide Treatment in Melanoma Leptomeningeal Carcinomatosis.
Journal: Case reports in oncology 20110101
Title: Medication safety of five oral chemotherapies: a proactive risk assessment.
Journal: Journal of oncology practice 20110101
Title: Long-term survival with primary glioblastoma multiforme: a clinical study in bulgarian patients.
Journal: Case reports in oncology 20110101
Title: Autologous peripheral blood mononuclear cell recognition of autologous proliferating tumor cells in the context of a patient-specific vaccine trial.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Integrin targeted therapeutics.
Journal: Theranostics 20110101
Title: Metastatic malignant melanoma presenting as an appendiceal mucocele.
Journal: Journal of oncology 20110101
Title: The beneficial effects of physical activity on impaired adult neurogenesis and cognitive performance.
Journal: Frontiers in neuroscience 20110101
Title: Preclinical testing of erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model.
Journal: Sarcoma 20110101
Title: High-dose chemotherapy with autologous hematopoietic stem-cell rescue for pediatric brain tumor patients: a single institution experience from UCLA.
Journal: Journal of transplantation 20110101
Title: Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer.
Journal: Journal of translational medicine 20110101
Title: Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells.
Journal: BMC cancer 20110101
Title: Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report.
Journal: Journal of medical case reports 20110101
Title: FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ.
Journal: PloS one 20110101
Title: Oncogene addiction in gliomas: implications for molecular targeted therapy.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Another cause of pancytopenia in a patient receiving temozolomide.
Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101
Title: Concordance of self-reported and medical chart information on cancer diagnosis and treatment.
Journal: BMC medical research methodology 20110101
Title: Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells.
Journal: Molecular cancer 20110101
Title: Extracranial propagation of glioblastoma with extension to pterygomaxillar fossa.
Journal: World journal of surgical oncology 20110101
Title: STAT6 expression in glioblastoma promotes invasive growth.
Journal: BMC cancer 20110101
Title: Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells.
Journal: Molecular cancer 20110101
Title: Kinetic studies of the effects of Temodal and quercetin on astrocytoma cells.
Journal: Pharmacological reports : PR 20110101
Title: The Clinical Value of PET with Amino Acid Tracers for Gliomas WHO Grade II.
Journal: International journal of molecular imaging 20110101
Title: Bevacizumab for the treatment of recurrent glioblastoma.
Journal: Clinical Medicine Insights. Oncology 20110101
Title: Novel diagnostic and therapeutic approaches to malignant glioma.
Journal: Swiss medical weekly 20110101
Title: Interpreting clinical assays for histone deacetylase inhibitors.
Journal: Cancer management and research 20110101
Title: MicroRNAs Regulate Key Effector Pathways of Senescence.
Journal: Journal of aging research 20110101
Title: Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation.
Journal: PloS one 20110101
Title: A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells.
Journal: Molecular cancer 20110101
Title: [Multimodal treatment of glioblastoma multiforme: results of 86 consecutive patients diagnosed in period 2003-2009].
Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101
Title: Transport processes of radiopharmaceuticals and -modulators.
Journal: Radiation oncology (London, England) 20110101
Title: Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival.
Journal: BMC medical genomics 20110101
Title: Epigenetic changes in cancer.
Journal: F1000 biology reports 20110101
Title: Morphological analysis of CDC2 and glycogen synthase kinase 3β phosphorylation as markers of g2 → m transition in glioma.
Journal: Pathology research international 20110101
Title: Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells.
Journal: Radiation oncology (London, England) 20110101
Title: Evolving diagnostic and treatment strategies for pancreatic neuroendocrine tumors.
Journal: Journal of hematology & oncology 20110101
Title: Application of hyperthermia induced by superparamagnetic iron oxide nanoparticles in glioma treatment.
Journal: International journal of nanomedicine 20110101
Title: Cancer stem cells and malignant gliomas. From pathophysiology to targeted molecular therapy.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101
Title: Concomitant temozolomide and radiotherapy versus radiotherapy alone for treatment of newly diagnosed glioblastoma multiforme.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101
Title: Serum granulocyte colony-stimulating factor levels in gliomas.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101
Title: Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells.
Journal: PloS one 20110101
Title: Identification of novel SNPs in glioblastoma using targeted resequencing.
Journal: PloS one 20110101
Title: Isolated central nervous system relapse of systemic lymphoma (SCNSL): clinical features and outcome of a retrospective analysis.
Journal: German medical science : GMS e-journal 20110101
Title: MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells.
Journal: PloS one 20110101
Title: Statistical quantification of methylation levels by next-generation sequencing.
Journal: PloS one 20110101
Title: Treatment of HIV-related primary central nervous system lymphoma with AZT high dose, HAART, interleukin-2 and foscarnet in three patients.
Journal: European journal of medical research 20110101
Title: Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair.
Journal: Oncology 20110101
Title: Aggressive silent corticotroph adenoma progressing to pituitary carcinoma: the role of temozolomide therapy.
Journal: Hormones (Athens, Greece) 20110101
Title: The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.
Journal: PloS one 20110101
Title: Brief report: phase II multicenter study of temozolomide in patients with cisplatin-resistant germ cell tumors.
Journal: Oncology 20110101
Title: Antiproliferative effects of Tubi-bee propolis in glioblastoma cell lines.
Journal: Genetics and molecular biology 20110101
Title: Induction of immune mediators in glioma and prostate cancer cells by non-lethal photodynamic therapy.
Journal: PloS one 20110101
Title: Enhancement of the click chemistry for the inverse Diels Alder technology by functionalization of amide-based monomers.
Journal: International journal of medical sciences 20110101
Title: The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation.
Journal: Molecular cancer 20110101
Title: Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas.
Journal: PloS one 20110101
Title: Therapeutic strategies to enhance the anticancer efficacy of histone deacetylase inhibitors.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Metformin plus temozolomide-based chemotherapy as adjuvant treatment for WHO grade III and IV malignant gliomas.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101
Title: Glioblastoma-derived leptin induces tube formation and growth of endothelial cells: comparison with VEGF effects.
Journal: BMC cancer 20110101
Title: Primary meningeal rhabdomyosarcoma.
Journal: Sarcoma 20110101
Title: Uveal melanoma.
Journal: Journal of skin cancer 20110101
Title: Teratoma with malignant transformation: a case report with pathological, cytogenetic, and immunohistochemistry analysis.
Journal: Sarcoma 20110101
Title: Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
Journal: BMC cancer 20110101
Title: Ifosfamide, carboplatin and etoposide in recurrent malignant glioma.
Journal: Oncology 20110101
Title: Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft.
Journal: Journal of translational medicine 20110101
Title: [Significant regression of glioblastoma with low level of Mgmt gene expression following radiotherapy].
Journal: Voprosy onkologii 20110101
Title: Drug therapy for hereditary cancers.
Journal: Hereditary cancer in clinical practice 20110101
Title: Extracranial skeletal metastasis in anaplastic oligodendroglioma: case report and review of the literature.
Journal: The Journal of international medical research 20110101
Title: Differences in the properties and mirna expression profiles between side populations from hepatic cancer cells and normal liver cells.
Journal: PloS one 20110101
Title: The role of integrins in glioma biology and anti-glioma therapies.
Journal: Current pharmaceutical design 20110101
Title: Why is there a lack of consensus on molecular subgroups of glioblastoma? Understanding the nature of biological and statistical variability in glioblastoma expression data.
Journal: PloS one 20110101
Title: Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma.
Journal: PloS one 20110101
Title: The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma.
Journal: PloS one 20110101
Title: Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme?
Journal: ASN neuro 20110101
Title: Efficacy of gamma knife radiosurgery for small-volume recurrent malignant gliomas after initial radical resection.
Journal: World neurosurgery 20110101
Title: Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region.
Journal: World neurosurgery 20110101
Title: Method for novel anti-cancer drug development using tumor explants of surgical specimens.
Journal: Journal of visualized experiments : JoVE 20110101
Title: Patient specification quality assurance for glioblastoma multiforme brain tumors treated with intensity modulated radiation therapy.
Journal: International journal of medical sciences 20110101
Title: β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance.
Journal: PloS one 20110101
Title: Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.
Journal: Chinese medicine 20110101
Title: Management options in triple-negative breast cancer.
Journal: Breast cancer : basic and clinical research 20110101
Title: Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres.
Journal: Journal of oncology 20110101
Title: Molecular characteristics of pediatric non-ependymal, non‑pilocytic gliomas associated with resistance to temozolomide.
Journal: Molecular medicine reports 20110101
Title: Molecular bases of cutaneous and uveal melanomas.
Journal: Pathology research international 20110101
Title: Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?
Journal: Breast cancer research : BCR 20110101
Title: BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells.
Journal: PloS one 20110101
Title: Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.
Journal: BMC cancer 20110101
Title: Formulation and evaluation of solid lipid nanoparticles of ramipril.
Journal: Journal of young pharmacists : JYP 20110101
Title: The combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53.
Journal: PloS one 20110101
Title: Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review.
Journal: Frontiers in pharmacology 20110101
Title: Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?
Journal: Radiation oncology (London, England) 20110101
Title: Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer.
Journal: PloS one 20110101
Title: Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma.
Journal: PloS one 20110101
Title: CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway.
Journal: PloS one 20110101
Title: Electrochemotherapy with cisplatin enhances local control after surgical ablation of fibrosarcoma in cats: an approach to improve the therapeutic index of highly toxic chemotherapy drugs.
Journal: Journal of translational medicine 20110101
Title: A spinal cord astrocytoma and its concurrent osteoblastic metastases at the time of the initial diagnosis: a case report and literature review.
Journal: Korean journal of radiology 20110101
Title: Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production.
Journal: PloS one 20110101
Title: Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms.
Journal: PloS one 20110101
Title: Evaluation of early imaging response criteria in glioblastoma multiforme.
Journal: Radiation oncology (London, England) 20110101
Title: Future of radiation therapy for malignant melanoma in an era of newer, more effective biological agents.
Journal: OncoTargets and therapy 20110101
Title: Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.
Journal: PloS one 20110101
Title: Diagnostic utility of IDH1- and p53-mutation analysis in secondary gliosarcoma.
Journal: Clinical neuropathology 20110101
Title: Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
Journal: PloS one 20110101
Title: MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes.
Journal: Lipids in health and disease 20110101
Title: Platinum resistance in breast and ovarian cancer cell lines.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: A simple guide screw method for intracranial xenograft studies in mice.
Journal: Journal of visualized experiments : JoVE 20110101
Title: Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells.
Journal: Radiation oncology (London, England) 20110101
Title: Fibronectin matrix assembly suppresses dispersal of glioblastoma cells.
Journal: PloS one 20110101
Title: The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma.
Journal: PloS one 20110101
Title: The challenges of managing glioblastoma multiforme in developing countries: a trade-off between cost and quality of care.
Journal: Hematology/oncology and stem cell therapy 20110101
Title: Outcomes of patients with metastatic melanoma treated with molecularly targeted agents in phase I clinical trials.
Journal: Oncology 20110101
Title: Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.
Journal: Molecular cancer 20110101
Title: Preoperative Visual Loss is the Main Cause of Irreversible Poor Vision in Children with a Brain Tumor.
Journal: Frontiers in neurology 20110101
Title: Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme.
Journal: PloS one 20110101
Title: Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor.
Journal: Molecular cancer 20110101
Title: Temozolomide-related infections: review of the literature.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101
Title: Treatment of liver metastases in patients with neuroendocrine tumors: a comprehensive review.
Journal: International journal of hepatology 20110101
Title: Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.
Journal: PloS one 20110101
Title: Toxicity after radiochemotherapy for glioblastoma using temozolomide--a retrospective evaluation.
Journal: Radiation oncology (London, England) 20110101
Title: Response to intrathecal infusions of Depocyt® in secondary diffuse leptomeningeal gliomatosis. A case report.
Journal: In vivo (Athens, Greece) 20110101
Title: Long survival of primary diffuse leptomeningeal gliomatosis following radiotherapy and temozolomide: case report and literature review.
Journal: European journal of medical research 20110101
Title: Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report.
Journal: Neurologia medico-chirurgica 20110101
Title: Evolving evidence implicates cytomegalovirus as a promoter of malignant glioma pathogenesis.
Journal: Herpesviridae 20110101
Title: Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells.
Journal: BMC cancer 20110101
Title: Invasion is not an independent prognostic factor in high-grade glioma.
Journal: Journal of cancer research and therapeutics 20110101
Title: The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.
Journal: PloS one 20110101
Title: Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3β/β-catenin signaling pathway.
Journal: PloS one 20110101
Title: Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.
Journal: Bone marrow research 20110101
Title: Ocular melanoma: Keep your eyes open for late brain metastases.
Journal: Surgical neurology international 20110101
Title: Mitochondrial peroxiredoxin III is a potential target for cancer therapy.
Journal: International journal of molecular sciences 20110101
Title: Rad51 and BRCA2--New molecular targets for sensitizing glioma cells to alkylating anticancer drugs.
Journal: PloS one 20110101
Title: Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr.
Journal: Radiation oncology (London, England) 20110101
Title: Anti-CTLA4 monoclonal antibodies: the past and the future in clinical application.
Journal: Journal of translational medicine 20110101
Title: Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
Journal: Clinical Medicine Insights. Oncology 20110101
Title: Clinical use of the low-molecular-weight heparins in cancer patients: focus on the improved patient outcomes.
Journal: Thrombosis 20110101
Title: Surgical brain metastases: management and outcome related to prognostic indexes: a critical review of a ten-year series.
Journal: ISRN surgery 20110101
Title: Cerebral melanoma metastases: a critical review on diagnostic methods and therapeutic options.
Journal: ISRN surgery 20110101
Title: [Issues around diffuse glioma].
Journal: Nederlands tijdschrift voor geneeskunde 20110101
Title: Innovative Therapies against Human Glioblastoma Multiforme.
Journal: ISRN oncology 20110101
Title: Albendazole sensitizes cancer cells to ionizing radiation.
Journal: Radiation oncology (London, England) 20110101
Title: Nanostructured Pt(NH(3))(4)Cl(2)/SiO(2) for nanomedicine: catalytic degradation of DNA in cancer cells.
Journal: Nano reviews 20110101
Title: Uptake and intracellular traffic of siRNA dendriplexes in glioblastoma cells and macrophages.
Journal: International journal of nanomedicine 20110101
Title: Diffusion MR Imaging of the Brain in Patients with Cancer.
Journal: International journal of molecular imaging 20110101
Title: The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications.
Journal: TheScientificWorldJournal 20110101
Title: The therapeutic potential of inhibitors of the signal transducer and activator of transcription 3 for central nervous system malignancies.
Journal: Surgical neurology international 20110101
Title: A facile synthesis and anticancer activity evaluation of spiro[thiazolidinone-isatin] conjugates.
Journal: Scientia pharmaceutica 20110101
Title: Intraventricular glioneuronal tumor with disseminated lesions at diagnosis--a case report.
Journal: Diagnostic pathology 20110101
Title: Postoperative deterioration in health related quality of life as predictor for survival in patients with glioblastoma: a prospective study.
Journal: PloS one 20110101
Title: An off-target nucleostemin RNAi inhibits growth in human glioblastoma-derived cancer stem cells.
Journal: PloS one 20110101
Title: BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance.
Journal: Journal of skin cancer 20110101
Title: Spinal radiosurgery--efficacy and safety after prior conventional radiotherapy.
Journal: Radiation oncology (London, England) 20110101
Title: Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide.
Journal: BMC cancer 20110101
Title: Morphometic analysis of TCGA glioblastoma multiforme.
Journal: BMC bioinformatics 20110101
Title: Radiotherapy and 'new' drugs-new side effects?
Journal: Radiation oncology (London, England) 20110101
Title: The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.
Journal: Stem cells international 20110101
Title: Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment.
Journal: Clinical & developmental immunology 20110101
Title: The immune response to tumors as a tool toward immunotherapy.
Journal: Clinical & developmental immunology 20110101
Title: Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review.
Journal: Diagnostic pathology 20110101
Title: Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
Journal: PloS one 20110101
Title: Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy.
Journal: Theranostics 20110101
Title: Evaluation of cancer stem cell migration using compartmentalizing microfluidic devices and live cell imaging.
Journal: Journal of visualized experiments : JoVE 20110101
Title: Two cases of cerebral sinus venous thrombosis following chemotherapy for non-seminomatous germ cell tumor.
Journal: Case reports in oncology 20110101
Title: Adjuvant therapy: melanoma.
Journal: Journal of skin cancer 20110101
Title: Radioembolization in the treatment of neuroendocrine tumor metastases to the liver.
Journal: International journal of hepatology 20110101
Title: [Brain metastasis in breast cancer].
Journal: Voprosy onkologii 20110101
Title: Neurosurgery concepts.
Journal: Surgical neurology international 20110101
Title: Profile of ipilimumab and its role in the treatment of metastatic melanoma.
Journal: Drug design, development and therapy 20110101
Title: Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A.
Journal: International journal of molecular sciences 20110101
Title: Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors.
Journal: Frontiers in molecular neuroscience 20110101
Title: The state of research into children with cancer across Europe: new policies for a new decade.
Journal: Ecancermedicalscience 20110101
Title: Typical bronchial carcinoid metastasizing to the brain: a case presentation.
Journal: Case reports in oncology 20110101
Title: The prospective role of plant products in radiotherapy of cancer: a current overview.
Journal: Frontiers in pharmacology 20110101
Title: Cisplatin tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant.
Journal: Chemotherapy research and practice 20110101
Title: New agents targeting angiogenesis in glioblastoma.
Journal: Chemotherapy research and practice 20110101
Title: Autophagy: friend or foe in breast cancer development, progression, and treatment.
Journal: International journal of breast cancer 20110101
Title: Bevacizumab improves quality of life in patients with recurrent glioblastoma.
Journal: Chemotherapy research and practice 20110101
Title: Triple-negative breast cancer: adjuvant therapeutic options.
Journal: Chemotherapy research and practice 20110101
Title: Glioma Indian scenario: Is there a human leucocyte antigen association?
Journal: Journal of natural science, biology, and medicine 20110101
Title: Ion channels in glioblastoma.
Journal: ISRN neurology 20110101
Title: Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery.
Journal: Frontiers in immunology 20110101
Title: Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers.
Journal: Frontiers in oncology 20110101
Title: Frontiers in cancer endocrinology.
Journal: Frontiers in endocrinology 20110101
Title: Combined modality approaches in the management of adult glioblastoma.
Journal: Frontiers in oncology 20110101
Title: Post-transcriptional regulation of O(6)-methylguanine-DNA methyltransferase MGMT in glioblastomas.
Journal: Cancer biomarkers : section A of Disease markers 20110101
Title: CXCR4-positive subset of glioma is enriched for cancer stem cells.
Journal: Oncology research 20110101
Title: Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.
Journal: The Journal of biological chemistry 20101224
Title: Synthesis and antitumor activity of 3-methyl-4-oxo-3,4-dihydroimidazo [5,1-d][1,2,3,5]tetrazine-8-carboxylates and -carboxamides.
Journal: Molecules (Basel, Switzerland) 20101220
Title: Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.
Journal: The Journal of biological chemistry 20101217
Title: Non-stem cell origin for oligodendroglioma.
Journal: Cancer cell 20101214
Title: Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
Journal: American journal of clinical oncology 20101201
Title: Tonsillar pseudotumor: complications of chronically-administered temozolomide.
Journal: Journal of neuro-oncology 20101201
Title: Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma.
Journal: Journal of neuro-oncology 20101201
Title: Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide.
Journal: Journal of neuro-oncology 20101201
Title: Receptor activation and inhibition in cellular response to chemotherapeutic combinational mimicries: the concept of divergent targeting.
Journal: Journal of neuro-oncology 20101201
Title: Autophagy and tumorigenesis.
Journal: Seminars in immunopathology 20101201
Title: Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group.
Journal: Pediatric blood & cancer 20101201
Title: Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma.
Journal: European journal of cancer (Oxford, England : 1990) 20101201
Title: A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma.
Journal: European journal of cancer (Oxford, England : 1990) 20101201
Title: MGMT immunoexpression in aggressive pituitary adenoma and carcinoma.
Journal: Pituitary 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20101201
Title: Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20101201
Title: [Glioblastoma incident studies from May 2006 to May 2007 in Angers and Nice, France].
Journal: Neuro-Chirurgie 20101201
Title: Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases.
Journal: European journal of endocrinology 20101201
Title: Unsuccessful high dose IL-2 therapy followed immediately by near continuous low dose temozolomide can result in rapid durable complete and near-complete remissions in metastatic melanoma.
Journal: Cancer biology & therapy 20101201
Title: Malignant melanoma as a target malignancy for the study of the anti-metastatic properties of the heparins.
Journal: Cancer metastasis reviews 20101201
Title: Temozolomide for adult brain stem glioblastoma: case report of a long-term survivor.
Journal: The International journal of neuroscience 20101201
Title: Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20101201
Title: [Chemotherapy and targeted treatments in glioblastomas].
Journal: Neuro-Chirurgie 20101201
Title: Glioblastoma: synergy of growth promotion between CCL5 and NK-1R can be thwarted by blocking CCL5 with miraviroc, an FDA approved anti-HIV drug and blocking NK-1R with aprepitant, an FDA approved anti-nausea drug.
Journal: Journal of clinical pharmacy and therapeutics 20101201
Title: Low immunohistochemical expression of MGMT in ACTH secreting pituitary tumors of patients with Nelson syndrome.
Journal: Endocrine pathology 20101201
Title: O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment.
Journal: Neurosurgery 20101201
Title: FDA accelerated approval benefits glioblastoma.
Journal: The Lancet. Oncology 20101201
Title: The tumor-immune microenvironment and response to radiation therapy.
Journal: Journal of mammary gland biology and neoplasia 20101201
Title: Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation.
Journal: Anti-cancer agents in medicinal chemistry 20101201
Title: AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers.
Journal: Oncotarget 20101201
Title: miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis.
Journal: Oncotarget 20101201
Title: Pseudoprogression following concurrent temozolomide and radiotherapy in a patient with glioblastoma: findings on functional imaging techniques.
Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20101201
Title: DecisionDx-GBM Gene Expression Assay for Prognostic Testing in Glioblastoma Multiform.
Journal: PLoS currents 20101126
Title: What role should cilengitide have in the treatment of glioblastoma?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120
Title: Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme.
Journal: International journal of cancer 20101115
Title: Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20101115
Title: Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101115
Title: MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature.
Journal: Cancer research 20101115
Title: [Carcinoid tumors].
Journal: Orvosi hetilap 20101114
Title: Phase II trial of sagopilone, a novel epothilone analog in metastatic melanoma.
Journal: British journal of cancer 20101109
Title: Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies.
Journal: British journal of cancer 20101109
Title: Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699.
Journal: British journal of cancer 20101109
Title: Long-term adjuvant administration of temozolomide in patients with glioblastoma multiforme: experience of a single institution.
Journal: Journal of cancer research and clinical oncology 20101101
Title: A prospective study of temozolomide plus thalidomide during and after radiation therapy for pediatric diffuse pontine gliomas: preliminary results of the Korean Society for Pediatric Neuro-Oncology study.
Journal: Journal of neuro-oncology 20101101
Title: Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid).
Journal: Pharmaceutical research 20101101
Title: Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis.
Journal: Journal of neuro-oncology 20101101
Title: Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance.
Journal: Journal of neuro-oncology 20101101
Title: KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells.
Journal: Brain pathology (Zurich, Switzerland) 20101101
Title: SOM230 (pasireotide) and temozolomide achieve sustained control of tumour progression and ACTH secretion in pituitary carcinoma with widespread metastases.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20101101
Title: Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.
Journal: Gene therapy 20101101
Title: Phase I study of temozolomide combined with oral etoposide in children with recurrent or progressive medulloblastoma.
Journal: European journal of cancer (Oxford, England : 1990) 20101101
Title: Management of ErbB2-positive breast cancer: insights from preclinical and clinical studies with lapatinib.
Journal: Japanese journal of clinical oncology 20101101
Title: Can high-dose fotemustine reverse MGMT resistance in glioblastoma multiforme?
Journal: Journal of neuro-oncology 20101101
Title: Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies.
Journal: Journal of molecular medicine (Berlin, Germany) 20101101
Title: MGMT gene promoter methylation in pediatric glioblastomas.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20101101
Title: The use of temozolomide for the treatment of malignant tumors: clinical evidence and molecular mechanisms of action.
Journal: Recent patents on anti-cancer drug discovery 20101101
Title: Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy.
Journal: Journal of neurology 20101101
Title: Quantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin™ and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase.
Journal: Biochemical pharmacology 20101101
Title: Molecular diagnostics of gliomas: state of the art.
Journal: Acta neuropathologica 20101101
Title: Targeting poly(ADP-ribose) polymerase activity for cancer therapy.
Journal: Cellular and molecular life sciences : CMLS 20101101
Title: A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma.
Journal: Neuro-oncology 20101101
Title: Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
Journal: Molecular pharmacology 20101101
Title: Small molecule inhibitors of DNA repair nuclease activities of APE1.
Journal: Cellular and molecular life sciences : CMLS 20101101
Title: Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101101
Title: Prolonged survival of a patient with cervical intramedullary glioblastoma multiforme treated with total resection, radiation therapy, and temozolomide.
Journal: Anti-cancer drugs 20101101
Title: Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101
Title: Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.
Journal: Archives of toxicology 20101101
Title: [Unknown gonadotoxicity chemotherapy and preservation of fertility: example of Temozolomide].
Journal: Gynecologie, obstetrique & fertilite 20101101
Title: Neuro-oncology, a decade of temozolomide and beyond.
Journal: Expert review of anticancer therapy 20101101
Title: [Malignant gliomas].
Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20101101
Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.
Journal: International journal of environmental research and public health 20101101
Title: Biodegradable microfibers deliver the antitumor drug temozolomide to glioma C6 cells in vitro.
Journal: Die Pharmazie 20101101
Title: Temozolomide: Expanding its role in brain cancer.
Journal: Drugs of today (Barcelona, Spain : 1998) 20101101
Title: Topoisomerase I inhibitors in the treatment of primary CNS malignancies: an update on recent trends.
Journal: Anti-cancer agents in medicinal chemistry 20101101
Title: Targeted toxins in brain tumor therapy.
Journal: Toxins 20101101
Title: Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres.
Journal: Cancer letters 20101028
Title: miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells.
Journal: Cancer letters 20101028
Title: Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models.
Journal: British journal of cancer 20101026
Title: IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
Journal: Neurology 20101026
Title: Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
Title: How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine.
Journal: British journal of cancer 20101012
Title: Establishment and characterisation of a new breast cancer xenograft obtained from a woman carrying a germline BRCA2 mutation.
Journal: British journal of cancer 20101012
Title: Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line.
Journal: Chemico-biological interactions 20101006
Title: Simultaneous integrated boost intensity-modulated radiotherapy in patients with high-grade gliomas.
Journal: International journal of radiation oncology, biology, physics 20101001
Title: Leptomeningeal gliomatosis as the initial presentation of gliomatosis cerebri.
Journal: Journal of neuro-oncology 20101001
Title: Steroid requirements during radiotherapy for malignant gliomas.
Journal: Journal of neuro-oncology 20101001
Title: Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.
Journal: Journal of neuro-oncology 20101001
Title: The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma.
Journal: Neurological research 20101001
Title: Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide.
Journal: Clinical neurology and neurosurgery 20101001
Title: Prolonged response without prolonged chemotherapy: a lesson from PCV chemotherapy in low-grade gliomas.
Journal: Neuro-oncology 20101001
Title: Experimental approaches for the treatment of malignant gliomas.
Journal: Pharmacology & therapeutics 20101001
Title: Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20101001
Title: A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
Journal: Neuro-oncology 20101001
Title: Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.
Journal: Clinical neurology and neurosurgery 20101001
Title: Core-shell hybrid nanogels for integration of optical temperature-sensing, targeted tumor cell imaging, and combined chemo-photothermal treatment.
Journal: Biomaterials 20101001
Title: Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience.
Journal: The Journal of clinical endocrinology and metabolism 20101001
Title: Nelson's syndrome.
Journal: European journal of endocrinology 20101001
Title: First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.
Journal: Neurosurgical review 20101001
Title: Circulating levels of the innate and humoral immune regulators CD14 and CD23 are associated with adult glioma.
Journal: Cancer research 20101001
Title: Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy.
Journal: Oncology reports 20101001
Title: In vitro novel combinations of psychotropics and anti-cancer modalities in U87 human glioblastoma cells.
Journal: International journal of oncology 20101001
Title: Ewing's sarcoma.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001
Title: Leptomeningeal metastases from small cell lung cancer responsive to temozolomide therapy.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001
Title: Oncolytic adenoviruses for the treatment of brain tumors.
Journal: Current opinion in molecular therapeutics 20101001
Title: Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas.
Journal: Expert review of neurotherapeutics 20101001
Title: Single-arm phase II study of conformal radiation therapy and temozolomide plus fractionated stereotactic conformal boost in high-grade gliomas: final report.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20101001
Title: Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.
Journal: Seminars in oncology 20101001
Title: An activating transcription factor 5-mediated survival pathway as a target for cancer therapy?
Journal: Oncotarget 20101001
Title: Pediatric primary intramedullary spinal cord glioblastoma.
Journal: Rare tumors 20100930
Title: Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth.
Journal: Oncogene 20100923
Title: MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
Journal: Brain research 20100917
Title: MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome.
Journal: British journal of cancer 20100907
Title: Combination of temozolomide with immunocytokine F16-IL2 for the treatment of glioblastoma.
Journal: British journal of cancer 20100907
Title: Prognostic and predictive value of p53 in low MGMT expressing glioblastoma treated with surgery, radiation and adjuvant temozolomide chemotherapy.
Journal: Neurological research 20100901
Title: alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells.
Journal: International journal of cancer 20100901
Title: Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20100901
Title: Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: a pilot study.
Journal: Journal of neuro-oncology 20100901
Title: MGMT immunoexpression in silent subtype 3 pituitary adenomas: possible therapeutic implications.
Journal: Endocrine pathology 20100901
Title: Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme.
Journal: Neuro-oncology 20100901
Title: Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20100901
Title: Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.
Journal: Cancer gene therapy 20100901
Title: Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide.
Journal: Neuro-oncology 20100901
Title: Temozolomide (Temodar).
Journal: AJNR. American journal of neuroradiology 20100901
Title: Comment on 'Non-surgical treatment of hormone-secreting pituitary tumors'.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100901
Title: Brain tumor stem cells as therapeutic targets in models of glioma.
Journal: Yonsei medical journal 20100901
Title: Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician's perspective.
Journal: Acta neuropathologica 20100901
Title: Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation.
Journal: Pediatric blood & cancer 20100901
Title: American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA.
Journal: Journal of neuro-oncology 20100901
Title: Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence.
Journal: Cancer research 20100901
Title: Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.
Journal: Neoplasia (New York, N.Y.) 20100901
Title: Urticarial hypersensitivity reaction caused by temozolomide.
Journal: Journal of drugs in dermatology : JDD 20100901
Title: Positron emission tomography/computed tomography: use for initial staging of malignant melanoma.
Journal: International journal of dermatology 20100901
Title: Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?
Journal: Future oncology (London, England) 20100901
Title: Glioblastoma multiforme in childhood: a case report.
Journal: Clinics (Sao Paulo, Brazil) 20100901
Title: Clinical significance of molecular biomarkers in glioblastoma.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100901
Title: Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival.
Journal: British journal of cancer 20100810
Title: Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature.
Journal: American journal of clinical oncology 20100801
Title: Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide.
Journal: Journal of neurosurgery 20100801
Title: Up-front temozolomide in elderly patients with glioblastoma.
Journal: Journal of neuro-oncology 20100801
Title: Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100801
Title: Phase II trial of neoadjuvant temozolomide in resectable melanoma patients.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100801
Title: MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
Journal: Neuro-oncology 20100801
Title: Inhibition of poly(ADP-ribose) polymerase enhances the effect of chemotherapy in an animal model of regional therapy for the treatment of advanced extremity malignant melanoma.
Journal: Annals of surgical oncology 20100801
Title: Genetic variations in EGF and EGFR and glioblastoma outcome.
Journal: Neuro-oncology 20100801
Title: Role of temozolomide in the treatment of newly diagnosed diffuse brainstem glioma in children: experience at a single institution.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20100801
Title: O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma.
Journal: International journal of clinical oncology 20100801
Title: A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme.
Journal: Journal of neurosurgery 20100801
Title: Oligodendroglial neoplasms with ganglioglioma-like maturation: a diagnostic pitfall.
Journal: Acta neuropathologica 20100801
Title: mTOR signaling in glioblastoma: lessons learned from bench to bedside.
Journal: Neuro-oncology 20100801
Title: DNA ligase IV is a potential molecular target in ACNU sensitivity.
Journal: Cancer science 20100801
Title: Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma.
Journal: Radiology 20100801
Title: Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme.
Journal: Cancer 20100801
Title: Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.
Journal: The Tohoku journal of experimental medicine 20100801
Title: Influence of iMRI-guidance on the extent of resection and survival of patients with glioblastoma multiforme.
Journal: Technology in cancer research & treatment 20100801
Title: [Neurological complications of neurooncological therapy].
Journal: Der Nervenarzt 20100801
Title: [Anaplastic glioma. Neuropathology, molecular diagnostics and current study concepts].
Journal: Der Nervenarzt 20100801
Title: Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma multiforme treated between 2002 and 2007: a multicenter study by the Central Nervous System Study Group of Airo (italian Association of Radiation Oncology).
Journal: Neurosurgery 20100801
Title: Long-term outcomes in children with glioblastoma.
Journal: Journal of neurosurgery. Pediatrics 20100801
Title: Rational use of anticancer drugs and patient lawsuits in the state of São Paulo, Southeastern Brazil.
Journal: Revista de saude publica 20100801
Title: Aplastic anemia with concurrent temozolomide treatment in a patient with glioblastoma multiforme.
Journal: Current oncology (Toronto, Ont.) 20100801
Title: Malignant progression of a pleomorphic xanthoastrocytoma in a child.
Journal: Neuropediatrics 20100801
Title: Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20100801
Title: Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1 mediated signaling.
Journal: Cell death & disease 20100801
Title: TP53 regulates human AlkB homologue 2 expression in glioma resistance to Photofrin-mediated photodynamic therapy.
Journal: British journal of cancer 20100727
Title: Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.
Journal: International journal of radiation oncology, biology, physics 20100701
Title: Monotherapy with methotrexate for primary central nervous lymphoma has single agent activity in the absence of radiotherapy: a single institution cohort.
Journal: Journal of neuro-oncology 20100701
Title: Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20100701
Title: The DNA methylome of glioblastoma multiforme.
Journal: Neurobiology of disease 20100701
Title: Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma?
Journal: Cancer investigation 20100701
Title: Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib.
Journal: Neurosurgical review 20100701
Title: Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004.
Journal: Neuro-oncology 20100701
Title: Sensitivity to temozolomide in brain tumor initiating cells.
Journal: Neuro-oncology 20100701
Title: Extended phase I evaluation of vincristine, irinotecan, temozolomide, and antibiotic in children with refractory solid tumors.
Journal: Pediatric blood & cancer 20100701
Title: Carmustine wafers (Gliadel) plus concomitant temozolomide therapy after resection of malignant astrocytoma: growing evidence for safety and efficacy.
Journal: Annals of surgical oncology 20100701
Title: Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
Journal: Annals of surgical oncology 20100701
Title: New drugs in neuroendocrine tumors: rising of new therapeutic philosophies?
Journal: Current opinion in oncology 20100701
Title: Stratifying osteosarcoma: minimizing and maximizing therapy.
Journal: Current oncology reports 20100701
Title: Initial experience involving treatment and retreatment with carmustine wafers in combination with oral temozolomide: long-term survival in a child with relapsed glioblastoma multiforme.
Journal: Journal of pediatric hematology/oncology 20100701
Title: PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
Journal: Cancer research 20100701
Title: Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival.
Journal: Journal of neuropathology and experimental neurology 20100701
Title: Long-term survival in patients with metastatic melanoma treated with DTIC or temozolomide.
Journal: The oncologist 20100701
Title: Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy.
Journal: Molecular cancer therapeutics 20100701
Title: The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.
Journal: Molecular cancer research : MCR 20100701
Title: Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: an assessment of clinical potential.
Journal: The British journal of radiology 20100701
Title: Analysis and stability study of temozolomide using capillary electrophoresis.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701
Title: Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
Journal: Oncotarget 20100701
Title: Newly diagnosed high-grade gliomas.
Journal: Current treatment options in neurology 20100701
Title: Recurrent high-grade glioma.
Journal: Current treatment options in neurology 20100701
Title: [Pituitary adenomas--where is the treatment heading at the beginning of the 21st century?].
Journal: Vnitrni lekarstvi 20100701
Title: Capecitabine and temozolomide: design, implementation, and preliminary outcomes from a pilot project to ensure safe prescribing of oral chemotherapy.
Journal: Journal of oncology practice 20100701
Title: Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Journal: Neuroscience 20100630
Title: Gliosarcoma: a study of four cases.
Journal: Rare tumors 20100630
Title: Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide.
Journal: British journal of cancer 20100629
Title: Emergence of cytomegalovirus disease in patients receiving temozolomide: report of two cases and literature review.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100615
Title: Dose-dense temozolomide regimens: antitumor activity, toxicity, and immunomodulatory effects.
Journal: Cancer 20100615
Title: Recurrent pituitary ependymoma: a complex clinical problem.
Journal: Pituitary 20100601
Title: O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
Journal: Lung cancer (Amsterdam, Netherlands) 20100601
Title: Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme?
Journal: American journal of clinical oncology 20100601
Title: Systematic analysis of the antiproliferative effects of novel and standard anticancer agents in rhabdoid tumor cell lines.
Journal: Anti-cancer drugs 20100601
Title: Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
Journal: Neuro-oncology 20100601
Title: Impact of splenectomy on thrombocytopenia, chemotherapy, and survival in patients with unresectable pancreatic cancer.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20100601
Title: Gene expression profiling predicts response to temozolomide in malignant gliomas.
Journal: International journal of oncology 20100601
Title: Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: a Portuguese multicentre study.
Journal: Oncology reports 20100601
Title: Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601
Title: Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent.
Journal: Current cancer drug targets 20100601
Title: Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia.
Journal: Clinical lymphoma, myeloma & leukemia 20100601
Title: Prolonged survival for patients with newly diagnosed, inoperable glioblastoma with 3-times daily ultrafractionated radiation therapy.
Journal: Neuro-oncology 20100601
Title: Targeted therapies in renal cell cancer: recent developments in imaging.
Journal: Targeted oncology 20100601
Title: The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases.
Journal: Current genomics 20100601
Title: Rationally designed pharmacogenomic treatment using concurrent capecitabine and radiotherapy for glioblastoma; gene expression profiles associated with outcome.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100515
Title: Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.
Journal: International journal of radiation oncology, biology, physics 20100501
Title: A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20100501
Title: A proposed classification system that projects outcomes based on preoperative variables for adult patients with glioblastoma multiforme.
Journal: Journal of neurosurgery 20100501
Title: Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients.
Journal: Journal of neurosurgery 20100501
Title: Primary CNS lymphoma in the elderly: temozolomide therapy and MGMT status.
Journal: Journal of neuro-oncology 20100501
Title: Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods.
Journal: Journal of neuro-oncology 20100501
Title: Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination.
Journal: Journal of neuro-oncology 20100501
Title: Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma.
Journal: Journal of neuro-oncology 20100501
Title: A case of primary leptomeningeal gliomatosis confined to the spinal cord.
Journal: Journal of neuro-oncology 20100501
Title: Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue.
Journal: Journal of neuro-oncology 20100501
Title: High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system.
Journal: Journal of neuro-oncology 20100501
Title: Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme.
Journal: Journal of neuro-oncology 20100501
Title: The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.
Journal: Pharmacological research 20100501
Title: Cordectomy as final treatment option for diffuse intramedullary malignant glioma using 5-ALA fluorescence-guided resection.
Journal: Clinical neurology and neurosurgery 20100501
Title: Loss of 1p, 19q, and 10q heterozygosity prospectively predicts prognosis of oligodendroglial tumors--towards individualized tumor treatment?
Journal: Neuro-oncology 20100501
Title: Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.
Journal: Stem cells (Dayton, Ohio) 20100501
Title: Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma.
Journal: Japanese journal of clinical oncology 20100501
Title: Parametric response map as an imaging biomarker to distinguish progression from pseudoprogression in high-grade glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501
Title: Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
Journal: Oncology reports 20100501
Title: Dummy run and conformity indices in the ongoing EORTC low-grade glioma trial 22033-26033: First evaluation of quality of radiotherapy planning.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20100501
Title: A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors.
Journal: Neuro-oncology 20100501
Title: Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial.
Journal: Neuro-oncology 20100501
Title: Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.
Journal: Molecular cancer therapeutics 20100501
Title: Management of low-grade glioma.
Journal: Current neurology and neuroscience reports 20100501
Title: Pseudoprogression after radiotherapy with concurrent temozolomide in a child with anaplastic astrocytoma.
Journal: Pediatric hematology and oncology 20100501
Title: Malignant transformation of an optic pathway glioma without prior radiation therapy.
Journal: Journal of neurosurgery. Pediatrics 20100501
Title: Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.
Journal: Clinical lung cancer 20100501
Title: Paternalism in practice: informing patients about expensive unsubsidised drugs.
Journal: Journal of medical ethics 20100501
Title: Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
Journal: Molecular cancer therapeutics 20100501
Title: High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100501
Title: From then to now: lessons from developments in our understanding of the pituitary gland.
Journal: The Ulster medical journal 20100501
Title: Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor.
Journal: Journal of medicinal chemistry 20100422
Title: Therapy for recurrent high-grade gliomas: does continuous dose-intense temozolomide have a role?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100420
Title: Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100420
Title: Commentary on Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial (Lancet Oncol. 2009;10:459-466).
Journal: Cancer 20100415
Title: Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.
Journal: Cancer research 20100415
Title: Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100415
Title: Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100415
Title: The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
Journal: Cancer research 20100415
Title: Determinants of survival in patients with brain metastases from cutaneous melanoma.
Journal: British journal of cancer 20100413
Title: Immunotherapy of pediatric brain tumor patients should include an immunoprevention strategy: a medical hypothesis paper.
Journal: Journal of neuro-oncology 20100401
Title: Phase I trial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: a Children's Oncology Group phase I consortium study.
Journal: Pediatric blood & cancer 20100401
Title: Temozolomide and cisplatin combination in naive patients with metastatic cutaneous melanoma: results of a phase II multicenter trial.
Journal: Melanoma research 20100401
Title: In-situ immobilization of quantum dots in polysaccharide-based nanogels for integration of optical pH-sensing, tumor cell imaging, and drug delivery.
Journal: Biomaterials 20100401
Title: The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.
Journal: Acta neuropathologica 20100401
Title: Myasthenia gravis developing in a patient with CNS lymphoma.
Journal: International journal of hematology 20100401
Title: An international validation study of the EORTC brain cancer module (EORTC QLQ-BN20) for assessing health-related quality of life and symptoms in brain cancer patients.
Journal: European journal of cancer (Oxford, England : 1990) 20100401
Title: PARP inhibition: PARP1 and beyond.
Journal: Nature reviews. Cancer 20100401
Title: A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.
Journal: Cancer research 20100401
Title: Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines.
Journal: Neuro-oncology 20100401
Title: Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
Journal: Neuro-oncology 20100401
Title: Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells.
Journal: Neuro-oncology 20100401
Title: Transferrin receptor 2 is frequently and highly expressed in glioblastomas.
Journal: Translational oncology 20100401
Title: Gene expression signatures as a guide to treatment strategies for in-transit metastatic melanoma.
Journal: Molecular cancer therapeutics 20100401
Title: Recent advances in combined modality therapy.
Journal: The oncologist 20100401
Title: Flow cytometric analysis for the mechanism of the new antineoplastic agent temozolomide in glioma cells.
Journal: Brain tumor pathology 20100401
Title: Pharmacogenetic application in personalized cancer treatment.
Journal: Acta medica Indonesiana 20100401
Title: Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
Journal: Neurosurgical review 20100401
Title: Chemotherapy with 5-fluorouracil, cisplatin and streptozocin for neuroendocrine tumours.
Journal: British journal of cancer 20100330
Title: Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis.
Journal: British journal of cancer 20100330
Title: In vivo assessment of temozolomide local delivery for lung cancer inhalation therapy.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100318
Title: Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010.
Journal: JOP : Journal of the pancreas 20100305
Title: [Glioblastoma multiforme--new hope due to modern therapeutical approaches].
Journal: Praxis 20100303
Title: Evaluation of the exposure equivalence of oral versus intravenous temozolomide.
Journal: Cancer chemotherapy and pharmacology 20100301
Title: Radiotherapy and concomitant temozolomide during the first and last weeks in high grade gliomas: long-term analysis of a phase II study.
Journal: Journal of neuro-oncology 20100301
Title: Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.
Journal: Journal of neuro-oncology 20100301
Title: Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.
Journal: Journal of neuro-oncology 20100301
Title: Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100301
Title: Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
Journal: Gene therapy 20100301
Title: Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients.
Journal: Cancer 20100301
Title: Comment on 'Opportunistic cytomegalovirus infection in a patient receiving temozolomide for treatment of malignant glioma'.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100301
Title: Temozolomide and MGMT forever?
Journal: Neuro-oncology 20100301
Title: Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice.
Journal: Neuro-oncology 20100301
Title: Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
Journal: Neuro-oncology 20100301
Title: O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications.
Journal: Neuro-oncology 20100301
Title: Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.
Journal: Neuro-oncology 20100301
Title: Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies.
Journal: Neuro-oncology 20100301
Title: Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
Journal: Neurosurgery 20100301
Title: Lestaurtinib enhances the antitumor efficacy of chemotherapy in murine xenograft models of neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100301
Title: Patent watch.
Journal: Nature reviews. Drug discovery 20100301
Title: The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKgamma/NF-kappaB-dependent pathway.
Journal: Journal of cell communication and signaling 20100301
Title: Recent advances in therapy for glioblastoma.
Journal: Archives of neurology 20100301
Title: Bevacizumab for malignant gliomas.
Journal: Archives of neurology 20100301
Title: A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
Journal: Archives of neurology 20100301
Title: Amelioration of symptoms and reduction of VIP levels after hepatic artery chemoembolization in a patient with sandostatin resistant VIPoma.
Journal: The Yale journal of biology and medicine 20100301
Title: Effectiveness of temozolomide treatment used at the same time with radiotherapy and adjuvant temozolomide; concomitant therapy of glioblastoma multiforme: multivariate analysis and other prognostic factors.
Journal: Journal of neurosurgical sciences 20100301
Title: The role of cytotoxic drugs in the treatment of central nervous system gliomas.
Journal: Acta neurologica Belgica 20100301
Title: Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
Journal: The Journal of biological chemistry 20100219
Title: Treatment options for small cell lung cancer - do we have more choice?
Journal: British journal of cancer 20100216
Title: A mathematical model of brain tumour response to radiotherapy and chemotherapy considering radiobiological aspects.
Journal: Journal of theoretical biology 20100207
Title: Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity.
Journal: Journal of neuro-oncology 20100201
Title: Different molecular patterns in glioblastoma multiforme subtypes upon recurrence.
Journal: Journal of neuro-oncology 20100201
Title: Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone.
Journal: Journal of neuro-oncology 20100201
Title: Extended-schedule dose-dense temozolomide in refractory gliomas.
Journal: Journal of neuro-oncology 20100201
Title: Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide.
Journal: Journal of neuro-oncology 20100201
Title: MGMT as a potential stratification marker in relapsed high-grade glioma of children: the HIT-GBM experience.
Journal: Pediatric blood & cancer 20100201
Title: Protein tyrosine phosphatases in glioma biology.
Journal: Acta neuropathologica 20100201
Title: The clinical efficacy of combination of docetaxel and temozolomide in previously treated patients with stage IV melanoma.
Journal: Melanoma research 20100201
Title: O-methylguanine-DNA methyltransferase immunoexpression in a double pituitary adenoma: case report.
Journal: Neurosurgery 20100201
Title: Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis.
Journal: Molecular cancer therapeutics 20100201
Title: Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100201
Title: Medical oncology: treatment and management of malignant gliomas.
Journal: Nature reviews. Clinical oncology 20100201
Title: Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma.
Journal: Molecular imaging 20100201
Title: Joint NCCTG and NABTC prognostic factors analysis for high-grade recurrent glioma.
Journal: Neuro-oncology 20100201
Title: The timing of cranial radiation in elderly patients with newly diagnosed glioblastoma multiforme.
Journal: Neuro-oncology 20100201
Title: Differential Effects of the Proteasome Inhibitor NPI-0052 against Glioma Cells.
Journal: Translational oncology 20100201
Title: Targeting A20 decreases glioma stem cell survival and tumor growth.
Journal: PLoS biology 20100201
Title: [Treatment of clinically nonfunctioning pituitary adenomas].
Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100201
Title: Effects of interleukin-1 receptor antagonist and chemotherapy on host-tumor interactions in established melanoma.
Journal: Anticancer research 20100201
Title: Bevacizumab is active as a single agent against recurrent malignant gliomas.
Journal: Anticancer research 20100201
Title: Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201
Title: The effect of Msh2 knockdown on methylating agent induced toxicity in DNA glycosylase deficient cells.
Journal: Toxicology 20100131
Title: Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508.
Journal: Cancer 20100115
Title: Galectins and gliomas.
Journal: Brain pathology (Zurich, Switzerland) 20100101
Title: Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
Journal: Journal of neurosurgery 20100101
Title: [11C]-L-methionine positron emission tomography in the management of children and young adults with brain tumors.
Journal: Journal of neuro-oncology 20100101
Title: Primary brain T-cell lymphoma of the lymphoblastic type presenting as altered mental status.
Journal: Acta neurochirurgica 20100101
Title: Effectiveness of temozolomide for primary glioblastoma multiforme in routine clinical practice.
Journal: Journal of neuro-oncology 20100101
Title: A human brainstem glioma xenograft model enabled for bioluminescence imaging.
Journal: Journal of neuro-oncology 20100101
Title: Salvage therapy with single agent bevacizumab for recurrent glioblastoma.
Journal: Journal of neuro-oncology 20100101
Title: Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials.
Journal: Journal of neuro-oncology 20100101
Title: Glioblastoma in elderly patients: safety and efficacy of adjuvant radiotherapy with concomitant temozolomide.
Journal: Archives of gerontology and geriatrics 20100101
Title: Volumetry of [(11)C]-methionine PET uptake and MRI contrast enhancement in patients with recurrent glioblastoma multiforme.
Journal: European journal of nuclear medicine and molecular imaging 20100101
Title: Rapid response to therapy of neurocutaneous melanosis with leptomeningeal melanoma.
Journal: Pediatric blood & cancer 20100101
Title: Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20100101
Title: Phase II study of fixed dose rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma multiforme.
Journal: Cancer chemotherapy and pharmacology 20100101
Title: Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection.
Journal: Neurosurgical review 20100101
Title: Concomitant or adjuvant temozolomide with whole-brain irradiation for brain metastases: a meta-analysis.
Journal: Anti-cancer drugs 20100101
Title: Oral atovaquone for the treatment of severe Pneumocystis jirovecii pneumonia in a patient with glucose-6-phosphate dehydrogenase deficiency.
Journal: Scandinavian journal of infectious diseases 20100101
Title: Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model.
Journal: Clinical and vaccine immunology : CVI 20100101
Title: Engineered drug-resistant immunocompetent cells enhance tumor cell killing during a chemotherapy challenge.
Journal: Biochemical and biophysical research communications 20100101
Title: EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma.
Journal: European journal of cancer (Oxford, England : 1990) 20100101
Title: The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics.
Journal: Journal of neuro-oncology 20100101
Title: The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal: Journal of neuro-oncology 20100101
Title: The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal: Journal of neuro-oncology 20100101
Title: The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal: Journal of neuro-oncology 20100101
Title: Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
Journal: Neurosurgery 20100101
Title: A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
Title: Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation.
Journal: Cancer research 20100101
Title: Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.
Journal: Journal of oncology 20100101
Title: The Diels-Alder-reaction with inverse-electron-demand, a very efficient versatile click-reaction concept for proper ligation of variable molecular partners.
Journal: International journal of medical sciences 20100101
Title: The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
Title: The Emerging Role of PARP Inhibitors in the Treatment of Epithelial Ovarian Cancer.
Journal: Journal of oncology 20100101
Title: Residual gammaH2AX foci as an indication of lethal DNA lesions.
Journal: BMC cancer 20100101
Title: Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital.
Journal: The oncologist 20100101
Title: Intravenously administered alphavirus vector VA7 eradicates orthotopic human glioma xenografts in nude mice.
Journal: PloS one 20100101
Title: Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells.
Journal: Neoplasia (New York, N.Y.) 20100101
Title: (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
Journal: Breast cancer research : BCR 20100101
Title: Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker.
Journal: Molecular cancer 20100101
Title: A phase II trial of the epothilone B analog ixabepilone (BMS-247550) in patients with metastatic melanoma.
Journal: PloS one 20100101
Title: Is there a place for radiotherapy in low-grade gliomas?
Journal: Advances and technical standards in neurosurgery 20100101
Title: Evaluation of adenovirus capsid labeling versus transgene expression.
Journal: Virology journal 20100101
Title: Bevacizumab: in previously treated glioblastoma.
Journal: Drugs 20100101
Title: Comparison of T2 and FLAIR imaging for target delineation in high grade gliomas.
Journal: Radiation oncology (London, England) 20100101
Title: Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model.
Journal: BMC cancer 20100101
Title: BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors.
Journal: BMC cancer 20100101
Title: U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line.
Journal: PLoS genetics 20100101
Title: Temozolomide in advanced and recurrent uterine leiomyosarcoma and correlation with o6-methylguanine DNA methyltransferase expression: a case series.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20100101
Title: A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI.
Journal: Radiation oncology (London, England) 20100101
Title: From basic research to clinical development of MEK1/2 inhibitors for cancer therapy.
Journal: Journal of hematology & oncology 20100101
Title: O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients.
Journal: Neuro-oncology 20100101
Title: Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
Journal: Neuro-oncology 20100101
Title: Noninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy.
Journal: Neuro-oncology 20100101
Title: Incorporating BCNU wafers into malignant glioma treatment: European case studies.
Journal: Clinical drug investigation 20100101
Title: Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.
Journal: BMC cancer 20100101
Title: Increased phosphorylation of vimentin in noninfiltrative meningiomas.
Journal: PloS one 20100101
Title: Pseudoprogression following chemoradiotherapy for glioblastoma multiforme.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100101
Title: Activated CD4+ T cells enhance radiation effect through the cooperation of interferon-gamma and TNF-alpha.
Journal: BMC cancer 20100101
Title: A patient with metastatic melanoma presenting with gastrointestinal perforation after dacarbazine infusion: a case report.
Journal: Journal of medical case reports 20100101
Title: CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors.
Journal: BMC cancer 20100101
Title: BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer.
Journal: Journal of oncology 20100101
Title: Current therapeutic paradigms in glioblastoma.
Journal: Reviews on recent clinical trials 20100101
Title: Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines.
Journal: BMC cancer 20100101
Title: Improved killing of human high-grade glioma cells by combining ionizing radiation with oncolytic parvovirus H-1 infection.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Temozolomide-induced myelodysplasia.
Journal: Advances in hematology 20100101
Title: A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy.
Journal: Molecular cancer 20100101
Title: MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients.
Journal: Neoplasma 20100101
Title: Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications.
Journal: Oncology 20100101
Title: Progress on antiangiogenic therapy for patients with malignant glioma.
Journal: Journal of oncology 20100101
Title: Postoperative chemo-radiotherapy with temodal in patients with glioblastoma multiforme--survival rates and prognostic factors.
Journal: Folia medica 20100101
Title: Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy.
Journal: Molecular cancer 20100101
Title: The bright and the dark sides of DNA repair in stem cells.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Melanoma: a model for testing new agents in combination therapies.
Journal: Journal of translational medicine 20100101
Title: Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report.
Journal: Nutrition & metabolism 20100101
Title: Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma.
Journal: Journal of oncology 20100101
Title: Molecular therapeutic targets for glioma angiogenesis.
Journal: Journal of oncology 20100101
Title: Astrocytes derived from trisomic human embryonic stem cells express markers of astrocytic cancer cells and premalignant stem-like progenitors.
Journal: BMC medical genomics 20100101
Title: Advances in the treatment of malignant gliomas.
Journal: Current oncology reports 20100101
Title: Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study.
Journal: BMC cancer 20100101
Title: Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.
Journal: PloS one 20100101
Title: Short-term radiotherapy followed by adjuvant chemotherapy in poor-prognosis patients with glioblastoma.
Journal: Tumori 20100101
Title: Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications.
Journal: Journal of carcinogenesis 20100101
Title: Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma.
Journal: CA: a cancer journal for clinicians 20100101
Title: Troglitazone reduces glyoxalase I protein expression in glioma and potentiates the effects of chemotherapeutic agents.
Journal: Journal of oncology 20100101
Title: Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms.
Journal: Breast cancer research : BCR 20100101
Title: Forecasting drug utilization and expenditure in a metropolitan health region.
Journal: BMC health services research 20100101
Title: Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma.
Journal: BMC cancer 20100101
Title: Preoperative chemotherapy for infiltrative low-grade oligoastrocytoma: a useful strategy to maximize surgical resection -case report-.
Journal: Neurologia medico-chirurgica 20100101
Title: Glioblastoma detected at the initial stage in its developmental process -case report-.
Journal: Neurologia medico-chirurgica 20100101
Title: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics.
Journal: Molecular cancer 20100101
Title: Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors.
Journal: PloS one 20100101
Title: Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: a systematic review and survival-gain analysis.
Journal: BMC cancer 20100101
Title: Carmustine and methotrexate in combination after whole brain radiation therapy in breast cancer patients presenting with brain metastases: a retrospective study.
Journal: BMC cancer 20100101
Title: CyberKnife enhanced conventionally fractionated chemoradiation for high grade glioma in close proximity to critical structures.
Journal: Journal of hematology & oncology 20100101
Title: Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy.
Journal: Molecular cancer 20100101
Title: T cells enhance stem-like properties and conditional malignancy in gliomas.
Journal: PloS one 20100101
Title: Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies.
Journal: Journal of translational medicine 20100101
Title: Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73.
Journal: BMC cancer 20100101
Title: Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial.
Journal: PloS one 20100101
Title: Health-related quality of life in glioma patients in China.
Journal: BMC cancer 20100101
Title: Gain of a 500-fold sensitivity on an intravital MR contrast agent based on an endohedral gadolinium-cluster-fullerene-conjugate: a new chance in cancer diagnostics.
Journal: International journal of medical sciences 20100101
Title: Hemorrhagic cystitis in a patient receiving docetaxel for prostate cancer.
Journal: Clinical Medicine Insights. Oncology 20100101
Title: ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro.
Journal: Molecular cancer 20100101
Title: A case of relapsed medulloblastoma treated with intensity-modulated radiotherapy and temozolomide.
Journal: Tumori 20100101
Title: Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells.
Journal: BMC cancer 20100101
Title: Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice.
Journal: PloS one 20100101
Title: Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells.
Journal: PloS one 20100101
Title: CTLA-4 blockade: therapeutic potential in cancer treatments.
Journal: OncoTargets and therapy 20100101
Title: New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab.
Journal: OncoTargets and therapy 20100101
Title: Anti-angiogenesis therapies: their potential in cancer management.
Journal: OncoTargets and therapy 20100101
Title: Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry.
Journal: International journal of medical sciences 20100101
Title: MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN.
Journal: BMC cancer 20100101
Title: Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.
Journal: Journal of oncology 20100101
Title: Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032.
Journal: Journal of translational medicine 20100101
Title: Decreasing glioma recurrence through adjuvant cancer stem cell inhibition.
Journal: Biologics : targets & therapy 20100101
Title: Angiogenesis and progression in human melanoma.
Journal: Dermatology research and practice 20100101
Title: Establishing intracranial brain tumor xenografts with subsequent analysis of tumor growth and response to therapy using bioluminescence imaging.
Journal: Journal of visualized experiments : JoVE 20100101
Title: Mesenchymal migration as a therapeutic target in glioblastoma.
Journal: Journal of oncology 20100101
Title: Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma.
Journal: BMC cancer 20100101
Title: Personalized therapies in the cancer 'omics' era.
Journal: Molecular cancer 20100101
Title: Oxidative stress and DNA methylation in prostate cancer.
Journal: Obstetrics and gynecology international 20100101
Title: Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability.
Journal: Genome integrity 20100101
Title: [Side effects of temozolomide treatment in patient with glioblastoma multiforme--case study].
Journal: Przeglad lekarski 20100101
Title: Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct.
Journal: Journal of neuroinflammation 20100101
Title: Impact of adjuvant chemotherapy for gliomatosis cerebri.
Journal: BMC cancer 20100101
Title: Targeted Therapy Database (TTD): a model to match patient's molecular profile with current knowledge on cancer biology.
Journal: PloS one 20100101
Title: Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-alpha 2b treatment.
Journal: Journal of translational medicine 20100101
Title: Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report.
Journal: Journal of medical case reports 20100101
Title: Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas.
Journal: BMC cancer 20100101
Title: Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment.
Journal: Neurologia medico-chirurgica 20100101
Title: Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report.
Journal: Neurologia medico-chirurgica 20100101
Title: Pituitary carcinoma diagnosed on fine needle aspiration: Report of a case and review of pathogenesis.
Journal: CytoJournal 20100101
Title: MRP3: a molecular target for human glioblastoma multiforme immunotherapy.
Journal: BMC cancer 20100101
Title: Herpesvirus vectors for therapy of brain tumors.
Journal: The open virology journal 20100101
Title: Coordination of glioblastoma cell motility by PKCι.
Journal: Molecular cancer 20100101
Title: Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.
Journal: BMC cancer 20100101
Title: Determining and interpreting correlations in lipidomic networks found in glioblastoma cells.
Journal: BMC systems biology 20100101
Title: An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients.
Journal: Molecular cancer 20100101
Title: Hypoxic regulation of cytoglobin and neuroglobin expression in human normal and tumor tissues.
Journal: Cancer cell international 20100101
Title: The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma.
Journal: Nutrition & metabolism 20100101
Title: The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas.
Journal: PloS one 20100101
Title: The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.
Journal: BMC cancer 20100101
Title: Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.
Journal: PloS one 20100101
Title: Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
Journal: PloS one 20100101
Title: Temozolomide in malignant glioma.
Journal: OncoTargets and therapy 20100101
Title: Hemorrhagic cystitis: A challenge to the urologist.
Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20100101
Title: Standard therapy for glioblastoma--a review of where we are.
Journal: Neurologia medico-chirurgica 20100101
Title: Bilateral posterior RION after concomitant radiochemotherapy with temozolomide in a patient with glioblastoma multiforme: a case report.
Journal: BMC cancer 20100101
Title: A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv 'Click Chemistry' targeted to αvβ3 integrin for therapy.
Journal: International journal of medical sciences 20100101
Title: Chemotherapy in Ewing's sarcoma.
Journal: Indian journal of orthopaedics 20100101
Title: A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: the CINDERELLA trial.
Journal: BMC cancer 20100101
Title: Nano to micro delivery systems: targeting angiogenesis in brain tumors.
Journal: Journal of angiogenesis research 20100101
Title: Unexpected high response rate to traditional therapy after dendritic cell-based vaccine in advanced melanoma: update of clinical outcome and subgroup analysis.
Journal: Clinical & developmental immunology 20100101
Title: Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O-Alkylguanine-DNA Alkyltransferase Activity.
Journal: Journal of nucleic acids 20100101
Title: FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors.
Journal: Molecular cancer 20100101
Title: Cellular and vaccine therapeutic approaches for gliomas.
Journal: Journal of translational medicine 20100101
Title: PARP inhibitors in BRCA1/BRCA2 germline mutation carriers with ovarian and breast cancer.
Journal: F1000 biology reports 20100101
Title: Overview of cellular immunotherapy for patients with glioblastoma.
Journal: Clinical & developmental immunology 20100101
Title: Targeting the osteosarcoma cancer stem cell.
Journal: Journal of orthopaedic surgery and research 20100101
Title: Treatment options for patients with triple-negative breast cancer.
Journal: Journal of hematology & oncology 20100101
Title: Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients.
Journal: Journal of nucleic acids 20100101
Title: Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone.
Journal: Breast cancer research : BCR 20100101
Title: HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression.
Journal: BMC cancer 20100101
Title: Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc.
Journal: BMC cancer 20100101
Title: Temozolomide-induced shrinkage of a pituitary carcinoma causing Cushing's disease--report of a case and literature review.
Journal: TheScientificWorldJournal 20100101
Title: External irradiation models for intracranial 9L glioma studies.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype.
Journal: PloS one 20100101
Title: Treatment of patients with atypical meningiomas Simpson grade 4 and 5 with a carbon ion boost in combination with postoperative photon radiotherapy: the MARCIE trial.
Journal: BMC cancer 20100101
Title: Conversion of a molecular classifier obtained by gene expression profiling into a classifier based on real-time PCR: a prognosis predictor for gliomas.
Journal: BMC medical genomics 20100101
Title: Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures.
Journal: BMC research notes 20100101
Title: High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study.
Journal: Journal of translational medicine 20100101
Title: Neck dissection and post-operative chemotherapy with dimethyl triazeno imidazole carboxamide and cisplatin protocol are useful for oral mucosal melanoma.
Journal: BMC cancer 20100101
Title: The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation.
Journal: Radiation oncology (London, England) 20100101
Title: Patient-oriented gene set analysis for cancer mutation data.
Journal: Genome biology 20100101
Title: DNA damage induced by alkylating agents and repair pathways.
Journal: Journal of nucleic acids 20100101
Title: Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation.
Journal: PloS one 20100101
Title: DNA methylation in glioblastoma: impact on gene expression and clinical outcome.
Journal: BMC genomics 20100101
Title: GNAS1 T393C polymorphism and disease progression in patients with malignant melanoma.
Journal: European journal of medical research 20100101
Title: Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB.
Journal: PloS one 20100101
Title: c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.
Journal: Molecular cancer 20100101
Title: Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003--a single institution's experience.
Journal: Radiation oncology (London, England) 20100101
Title: Role of bevacizumab therapy in the management of glioblastoma.
Journal: Cancer management and research 20100101
Title: Treatment of cutaneous melanoma: current approaches and future prospects.
Journal: Cancer management and research 20100101
Title: Epigenomics in cancer management.
Journal: Cancer management and research 20100101
Title: Anaplastic pleomorphic xanthoastrocytoma with a component of anaplastic astrocytoma presenting as skull base tumor followed by downward extracranial extension. Case report.
Journal: Neurologia medico-chirurgica 20100101
Title: A phase II trial of sorafenib in metastatic melanoma with tissue correlates.
Journal: PloS one 20100101
Title: Youngest case of third ventricular anaplastic neurocytoma.
Journal: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20100101
Title: An unusual case of aplastic anemia caused by temozolomide.
Journal: Case reports in medicine 20100101
Title: Arsenic trioxide sensitizes cancer stem cells to chemoradiotherapy. A new approach in the treatment of inoperable glioblastoma multiforme.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101
Title: Establishment of prognostic models for astrocytic and oligodendroglial brain tumors with standardized quantification of marker gene expression and clinical variables.
Journal: Biomarker insights 20100101
Title: UK Guidelines for the Management of Bone Sarcomas.
Journal: Sarcoma 20100101
Title: Treatment of glioblastoma in elderly patients: an overview of current treatments and future perspective.
Journal: Tumori 20100101
Title: Chemopotentiation by ultrafractionated radiotherapy in glioblastoma resistant to conventional therapy.
Journal: Tumori 20100101
Title: [New therapeutic options in therapy of glioblastoma multiforme].
Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20100101
Title: Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme.
Journal: Cell death & disease 20100101
Title: Immunotherapy of brain cancers: the past, the present, and future directions.
Journal: Clinical & developmental immunology 20100101
Title: Treating glioblastoma multiforme with electrical fields.
Journal: World neurosurgery 20100101
Title: Tardy spinal cord tumor following avulsive brachial plexus injury: coincidental or causal?
Journal: World neurosurgery 20100101
Title: Supratentorial glioblastoma multiforme with spinal metastases.
Journal: Journal of craniovertebral junction & spine 20100101
Title: Alterations in gene expression profiles correlated with cisplatin cytotoxicity in the glioma U343 cell line.
Journal: Genetics and molecular biology 20100101
Title: Advances in the treatment of gastroenteropancreatic neuroendocrine tumors.
Journal: Clinical and experimental gastroenterology 20100101
Title: Hybrid micro-/nanogels for optical sensing and intracellular imaging.
Journal: Nano reviews 20100101
Title: The role of funding and policies on innovation in cancer drug development.
Journal: Ecancermedicalscience 20100101
Title: High-quality genomic DNA extraction from formalin-fixed and paraffin-embedded samples deparaffinized using mineral oil.
Journal: Analytical biochemistry 20091215
Title: Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk?
Journal: Pediatric blood & cancer 20091215
Title: Primary leptomeningeal anaplastic oligodendroglioma with a 1p36-19q13 deletion: report of a unique case successfully treated with Temozolomide.
Journal: Journal of the neurological sciences 20091215
Title: Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma.
Journal: British journal of cancer 20091215
Title: Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study.
Journal: British journal of cancer 20091215
Title: Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected].
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210
Title: MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210
Title: NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210
Title: Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.
Journal: Neuro-oncology 20091201
Title: Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
Journal: Neuro-oncology 20091201
Title: Combined multiple surgical intervention and chemotherapy for multicentric WHO grade II glioma : a long-term follow-up study.
Journal: Acta neurochirurgica 20091201
Title: Pharmacokinetics of temozolomide administered in combination with O6-benzylguanine in children and adolescents with refractory solid tumors.
Journal: Cancer chemotherapy and pharmacology 20091201
Title: Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
Journal: Journal of neuro-oncology 20091201
Title: Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
Journal: Journal of neuro-oncology 20091201
Title: Neurological outcome of long-term glioblastoma survivors.
Journal: Journal of neuro-oncology 20091201
Title: Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience.
Journal: Pediatric blood & cancer 20091201
Title: High-grade glioma mouse models and their applicability for preclinical testing.
Journal: Cancer treatment reviews 20091201
Title: Classification and management of anaplastic gliomas.
Journal: Current opinion in neurology 20091201
Title: Treatment of recurrent high-grade gliomas.
Journal: Current opinion in neurology 20091201
Title: Combining drugs and radiotherapy: from the bench to the bedside.
Journal: Current opinion in neurology 20091201
Title: Pseudoprogression and pseudoresponse in the treatment of gliomas.
Journal: Current opinion in neurology 20091201
Title: Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091201
Title: A novel use of temozolomide in a patient with malignant prolactinoma.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20091201
Title: Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent.
Journal: International journal of radiation oncology, biology, physics 20091201
Title: Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells.
Journal: Molecular cancer research : MCR 20091201
Title: ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091201
Title: Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.
Journal: Molecular cancer therapeutics 20091201
Title: A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.
Journal: Molecular cancer research : MCR 20091201
Title: Chemotherapy for glioblastoma: current treatment and future perspectives for cytotoxic and targeted agents.
Journal: Anticancer research 20091201
Title: Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide.
Journal: Anticancer research 20091201
Title: Therapeutic windows.
Journal: Molecular interventions 20091201
Title: Redox-related antimelanoma activity of ATN-224.
Journal: Melanoma research 20091201
Title: IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.
Journal: Neurology 20091124
Title: Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study.
Journal: British journal of cancer 20091117
Title: Bevacizumab for recurrent ependymoma.
Journal: Neurology 20091117
Title: Antiangiogenesis in recurrent glioblastoma: proof of principle.
Journal: Neurology international 20091116
Title: Results of a multicenter, randomized, double-blind, dose-evaluating phase 2/3 study of lenalidomide in the treatment of metastatic malignant melanoma.
Journal: Cancer 20091115
Title: The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091115
Title: Current data and strategy in glioblastoma multiforme.
Journal: Journal of medicine and life 20091115
Title: Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents.
Journal: Journal of medicinal chemistry 20091112
Title: Primary malignant melanoma of the vagina.
Journal: Archives of gynecology and obstetrics 20091101
Title: Preoperative intensity-modulated radiotherapy combined with temozolomide for locally advanced soft-tissue sarcoma.
Journal: International journal of radiation oncology, biology, physics 20091101
Title: Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
Journal: Cancer chemotherapy and pharmacology 20091101
Title: Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.
Journal: Journal of neuro-oncology 20091101
Title: Screening of anti-glioma effects induced by sigma-1 receptor ligands: potential new use for old anti-psychiatric medicines.
Journal: European journal of cancer (Oxford, England : 1990) 20091101
Title: Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas.
Journal: Clinical neurology and neurosurgery 20091101
Title: Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors.
Journal: Bioorganic & medicinal chemistry 20091101
Title: New advances that enable identification of glioblastoma recurrence.
Journal: Nature reviews. Clinical oncology 20091101
Title: The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas.
Journal: Neurosurgery 20091101
Title: Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091101
Title: Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair.
Journal: Nuclear medicine and biology 20091101
Title: Current developments in the radiotherapy approach to elderly and frail patients with glioblastoma multiforme.
Journal: Expert review of anticancer therapy 20091101
Title: FDA drug approval summary: bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme.
Journal: The oncologist 20091101
Title: The importance of tumor volume in the prognosis of patients with glioblastoma: comparison of computerized volumetry and geometric models.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20091101
Title: Glioblastoma multiforme associated with klinefelter syndrome.
Journal: Neurologia medico-chirurgica 20091101
Title: Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.
Journal: Anticancer research 20091101
Title: Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development.
Journal: Biochemistry 20091027
Title: NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma.
Journal: British journal of cancer 20091020
Title: Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling.
Journal: Cancer letters 20091018
Title: Temozolomide for recurrent intracranial supratentorial platinum-refractory ependymoma.
Journal: Cancer 20091015
Title: Enhancement of cancer chemotherapy by simultaneously altering cell cycle progression and DNA-damage defenses through global modification of the serine/threonine phospho-proteome.
Journal: Cell cycle (Georgetown, Tex.) 20091015
Title: Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity.
Journal: British journal of cancer 20091006
Title: DNA ligase IV as a new molecular target for temozolomide.
Journal: Biochemical and biophysical research communications 20091002
Title: Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.
Journal: Surgical neurology 20091001
Title: Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model.
Journal: Cancer immunology, immunotherapy : CII 20091001
Title: Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
Journal: Neuro-oncology 20091001
Title: CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.
Journal: Cancer gene therapy 20091001
Title: Early metabolic responses in temozolomide treated low-grade glioma patients.
Journal: Journal of neuro-oncology 20091001
Title: Glioma-associated endothelial cells are chemoresistant to temozolomide.
Journal: Journal of neuro-oncology 20091001
Title: Non-Hodgkin lymphoma following temozolomide.
Journal: Pediatric blood & cancer 20091001
Title: The prognostic role of Beclin 1 protein expression in high-grade gliomas.
Journal: Autophagy 20091001
Title: Management of glioblastoma multiforme in HIV patients: a case series and review of published studies.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20091001
Title: High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing's disease.
Journal: European journal of endocrinology 20091001
Title: A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells.
Journal: Cancer chemotherapy and pharmacology 20091001
Title: Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: single-center experience.
Journal: Clinical neurology and neurosurgery 20091001
Title: The translesion polymerase Rev3L in the tolerance of alkylating anticancer drugs.
Journal: Molecular pharmacology 20091001
Title: Temozolomide treatment of a pituitary carcinoma and two pituitary macroadenomas resistant to conventional therapy.
Journal: European journal of endocrinology 20091001
Title: Insights into pharmacotherapy of malignant glioma in adults.
Journal: Expert opinion on pharmacotherapy 20091001
Title: Neurological adverse effects caused by cytotoxic and targeted therapies.
Journal: Nature reviews. Clinical oncology 20091001
Title: Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors.
Journal: Oncology reports 20091001
Title: Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model.
Journal: Cancer biology & therapy 20091001
Title: Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians.
Journal: Pharmacogenetics and genomics 20091001
Title: Rituximab maintenance therapy in central nervous system lymphoma?
Journal: Leukemia & lymphoma 20091001
Title: Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a prerequisite for low-dose radiation hypersensitivity.
Journal: Radiation research 20091001
Title: Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
Title: Acquired resistance to combination treatment with temozolomide and ABT-888 is mediated by both base excision repair and homologous recombination DNA repair pathways.
Journal: Molecular cancer research : MCR 20091001
Title: Supratentorial, extraventricular choroid plexus carcinoma in an adult: case report.
Journal: Neurosurgery 20091001
Title: p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor.
Journal: Anticancer research 20091001
Title: Role of MGMT in tumor development, progression, diagnosis, treatment and prognosis.
Journal: Anticancer research 20091001
Title: A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.
Journal: Anticancer research 20091001
Title: [Medical management of primary central nervous system lymphoma refractory or resistant to standard of care treatment].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20091001
Title: Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.
Journal: British journal of cancer 20090915
Title: Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
Journal: Cancer chemotherapy and pharmacology 20090901
Title: The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment.
Journal: Journal of cellular and molecular medicine 20090901
Title: Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents.
Journal: Cancer chemotherapy and pharmacology 20090901
Title: Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy.
Journal: Journal of cancer research and clinical oncology 20090901
Title: Primary leptomeningeal oligodendrogliomatosis.
Journal: Journal of neuro-oncology 20090901
Title: Use of FDA approved methamphetamine to allow adjunctive use of methylnaltrexone to mediate core anti-growth factor signaling effects in glioblastoma.
Journal: Journal of neuro-oncology 20090901
Title: Disseminated strongyloidiasis complicating glioblastoma therapy: a case report.
Journal: Journal of neuro-oncology 20090901
Title: Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection.
Journal: Journal of neuro-oncology 20090901
Title: Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide.
Journal: Journal of neuro-oncology 20090901
Title: Combined radio- and chemotherapy of brain tumours in adult patients.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20090901
Title: Clinical utility of temozolomide in the treatment of malignant paraganglioma: a preliminary report.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901
Title: Combined modality treatment of newly diagnosed glioblastoma multiforme in a regional neurosurgical centre.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090901
Title: Temozolomide in malignant gliomas: current use and future targets.
Journal: Cancer chemotherapy and pharmacology 20090901
Title: Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090901
Title: In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma.
Journal: European journal of cancer (Oxford, England : 1990) 20090901
Title: A rare case of aplastic anemia caused by temozolomide.
Journal: Southern medical journal 20090901
Title: Treatment of malignant pheochromocytoma.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901
Title: Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
Journal: International journal of radiation oncology, biology, physics 20090901
Title: Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall.
Journal: Neurologia medico-chirurgica 20090901
Title: Population-based study of pseudoprogression after chemoradiotherapy in GBM.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20090901
Title: Recurrent PNET with MGMT methylation responds to temozolomide.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20090901
Title: [Pituitary carcinomas and aggressive adenomas: an overview and new therapeutic options].
Journal: Annales d'endocrinologie 20090901
Title: Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.
Journal: Acta neurologica Belgica 20090901
Title: Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model.
Journal: Cancer letters 20090818
Title: Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.
Journal: British journal of cancer 20090818
Title: Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810
Title: Societal preference values for advanced melanoma health states in the United Kingdom and Australia.
Journal: British journal of cancer 20090804
Title: MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea.
Journal: British journal of cancer 20090804
Title: [A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma].
Journal: Zhonghua yi xue za zhi 20090804
Title: Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours.
Journal: Clinical endocrinology 20090801
Title: Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology?
Journal: Journal of neuro-oncology 20090801
Title: Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.
Journal: Journal of neurosurgery 20090801
Title: Cisplatinum and BCNU chemotherapy in primary glioblastoma patients.
Journal: Journal of neuro-oncology 20090801
Title: Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression.
Journal: Journal of neuro-oncology 20090801
Title: Pseudoprogression in boron neutron capture therapy for malignant gliomas and meningiomas.
Journal: Neuro-oncology 20090801
Title: Low-grade gliomas.
Journal: Current treatment options in oncology 20090801
Title: The role of chemotherapy for pure and mixed anaplastic oligodendroglial tumors.
Journal: Current treatment options in oncology 20090801
Title: IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
Journal: International journal of cancer 20090801
Title: Cancer cell death by design: apoptosis, autophagy and glioma virotherapy.
Journal: Autophagy 20090801
Title: A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.
Journal: Cancer investigation 20090801
Title: Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
Journal: Cancer 20090801
Title: Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status.
Journal: Cancer 20090801
Title: Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Journal: Melanoma research 20090801
Title: Small molecules and targeted therapies in distant metastatic disease.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090801
Title: Immunotherapy of distant metastatic disease.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090801
Title: Comment re: Temozolomide preferentially depletes cancer stem cells.
Journal: Cancer research 20090801
Title: Prolonged cell cycle response of HeLa cells to low-level alkylation exposure.
Journal: Cancer research 20090801
Title: Diagnosis and management of leptomeningeal disease.
Journal: Clinical journal of oncology nursing 20090801
Title: Hypersensitivity pneumonitis associated with temozolomide.
Journal: The European respiratory journal 20090801
Title: Perioperative high-dose-rate brachytherapy in the treatment of recurrent malignant gliomas.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20090801
Title: Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.
Journal: Anticancer research 20090801
Title: First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity.
Journal: Anticancer research 20090801
Title: Poly(ADP-ribose) polymerase inhibitor ABT-888 potentiates the cytotoxic activity of temozolomide in leukemia cells: influence of mismatch repair status and O6-methylguanine-DNA methyltransferase activity.
Journal: Molecular cancer therapeutics 20090801
Title: [Recent trends in the pathophysiology and treatment of pituitary adenomas].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090801
Title: Radiotherapy for metastatic brain tumors.
Journal: International journal of clinical oncology 20090801
Title: Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines.
Journal: British journal of cancer 20090721
Title: MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090715
Title: Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.
Journal: British journal of cancer 20090707
Title: High-dose radiotherapy to 78 Gy with or without temozolomide for high grade gliomas.
Journal: Journal of neuro-oncology 20090701
Title: Imaging biological activity of a glioblastoma treated with an individual patient-tailored, experimental therapy regimen.
Journal: Journal of neuro-oncology 20090701
Title: Multiple intracranial melanoma metastases: case report and review of the literature.
Journal: Journal of neuro-oncology 20090701
Title: Cerebral astroblastoma: analysis of six cases and critical review of treatment options.
Journal: Journal of neuro-oncology 20090701
Title: Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma.
Journal: Pediatric blood & cancer 20090701
Title: Initial clinical experience with frameless optically guided stereotactic radiosurgery/radiotherapy in pediatric patients.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20090701
Title: Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
Journal: Cancer 20090701
Title: The safety of temozolomide in the treatment of malignancies.
Journal: Expert opinion on drug safety 20090701
Title: New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors.
Journal: Current opinion in oncology 20090701
Title: Functional and metabolic magnetic resonance imaging and positron emission tomography for tumor volume definition in high-grade gliomas.
Journal: Seminars in radiation oncology 20090701
Title: In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
Journal: The Journal of clinical investigation 20090701
Title: Effect of IFN-beta on human glioma cell lines with temozolomide resistance.
Journal: International journal of oncology 20090701
Title: Glioblastoma multiforme.
Journal: Current treatment options in neurology 20090701
Title: Treatment of spinal cord tumors.
Journal: Current treatment options in neurology 20090701
Title: Narciclasine, a plant growth modulator, activates Rho and stress fibers in glioblastoma cells.
Journal: Molecular cancer therapeutics 20090701
Title: FEN1 is overexpressed in testis, lung and brain tumors.
Journal: Anticancer research 20090701
Title: Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.
Journal: Anticancer research 20090701
Title: [Clinicopathological diagnosis of gliomas by genotype analysis].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090701
Title: [Treatment of glioma with temozolomide].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090701
Title: Glioblastoma stem cells resistant to temozolomide-induced autophagy.
Journal: Chinese medical journal 20090605
Title: Mechanism of thalidomide to enhance cytotoxicity of temozolomide in U251-MG glioma cells in vitro.
Journal: Chinese medical journal 20090605
Title: [Atypical pseudotumoral neuromeningeal cryptococcosis in an immunocompromised patient treated for pontine glioma. Case report and literature review].
Journal: Neuro-Chirurgie 20090601
Title: Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts.
Journal: Neuro-oncology 20090601
Title: Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model.
Journal: Neuro-oncology 20090601
Title: Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma.
Journal: Cancer chemotherapy and pharmacology 20090601
Title: Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide.
Journal: The Journal of investigative dermatology 20090601
Title: Phase I trial using proteasome inhibitor bortezomib and concurrent temozolomide and radiotherapy for central nervous system malignancies.
Journal: International journal of radiation oncology, biology, physics 20090601
Title: Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia.
Journal: Journal of neuro-oncology 20090601
Title: Disposition of temozolomide in a patient with glioblastoma multiforme after gastric bypass surgery.
Journal: Journal of neuro-oncology 20090601
Title: Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.
Journal: Journal of neuro-oncology 20090601
Title: Radiological progression of cerebral metastases after radiosurgery: assessment of perfusion MRI for differentiating between necrosis and recurrence.
Journal: Journal of neurology 20090601
Title: Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090601
Title: Concurrent radiotherapy: fotemustine combination for newly diagnosed malignant glioma patients, a phase II study.
Journal: Cancer chemotherapy and pharmacology 20090601
Title: p15 promoter methylation - a novel prognostic marker in glioblastoma patients.
Journal: International journal of oncology 20090601
Title: Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma.
Journal: Melanoma research 20090601
Title: The history and future of chemotherapy for melanoma.
Journal: Hematology/oncology clinics of North America 20090601
Title: Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.
Journal: Molecular cancer research : MCR 20090601
Title: Novel therapeutics for melanoma.
Journal: Expert review of anticancer therapy 20090601
Title: Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme.
Journal: Expert review of pharmacoeconomics & outcomes research 20090601
Title: A network of conserved damage survival pathways revealed by a genomic RNAi screen.
Journal: PLoS genetics 20090601
Title: Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis.
Journal: Journal of neurosurgery. Spine 20090601
Title: Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
Journal: Journal of chemotherapy (Florence, Italy) 20090601
Title: [Central nervous system glioma. Multi-drug chemotherapy including temozolomide].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20090601
Title: [Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090601
Title: Mapping the literature: role of trabectedin as a new chemotherapy option in advanced pretreated soft tissue sarcoma.
Journal: Drugs of today (Barcelona, Spain : 1998) 20090601
Title: Cerebellar glioblastoma in the elderly--case report.
Journal: Acta clinica Croatica 20090601
Title: Molecular markers of tumor progression in melanoma.
Journal: Current genomics 20090601
Title: The outcomes of concomitant radiation plus temozolomide followed by adjuvant temozolomide for newly diagnosed high grade gliomas: the preliminary results of single center prospective study.
Journal: Journal of the Egyptian National Cancer Institute 20090601
Title: Dose escalation methods in phase I cancer clinical trials.
Journal: Journal of the National Cancer Institute 20090520
Title: Molecular classification of solid tumours: towards pathway-driven therapeutics.
Journal: British journal of cancer 20090519
Title: The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2.
Journal: Biochemical pharmacology 20090515
Title: EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
Journal: Cancer research 20090515
Title: Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090515
Title: Bevacizumab and irinotecan for recurrent oligodendroglial tumors.
Journal: Neurology 20090505
Title: Efficacy of temozolomide for recurrent embryonal brain tumors in children.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20090501
Title: Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis?
Journal: Clinical neurology and neurosurgery 20090501
Title: Rechallenge with temozolomide in patients with recurrent gliomas.
Journal: Journal of neurology 20090501
Title: Occipital ganglio-neuroblastoma in an adult.
Journal: Acta neurochirurgica 20090501
Title: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
Journal: The Lancet. Oncology 20090501
Title: The combination topotecan, temozolomide and dexamethasone associated with radiotherapy as treatment of central nervous system myeloma relapse.
Journal: International journal of hematology 20090501
Title: Progress in the treatment of neuroendocrine tumors.
Journal: Current oncology reports 20090501
Title: Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells.
Journal: Molecular cancer research : MCR 20090501
Title: Treatment options for recurrent glioblastoma: pitfalls and future trends.
Journal: Expert review of anticancer therapy 20090501
Title: [Prescription guidebook for temozolomide usage in brain tumors].
Journal: Bulletin du cancer 20090501
Title: Structural adaptation and heterogeneity of normal and tumor microvascular networks.
Journal: PLoS computational biology 20090501
Title: Methodological approaches in application of synthetic lethality screening towards anticancer therapy.
Journal: British journal of cancer 20090421
Title: A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.
Journal: British journal of cancer 20090421
Title: O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib.
Journal: British journal of cancer 20090421
Title: Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article.
Journal: Molecules (Basel, Switzerland) 20090416
Title: Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma.
Journal: Cancer 20090415
Title: Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.
Journal: British journal of cancer 20090407
Title: RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs.
Journal: Brain pathology (Zurich, Switzerland) 20090401
Title: Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
Journal: Neuro-oncology 20090401
Title: Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131.
Journal: Neuro-oncology 20090401
Title: Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Journal: Neuro-oncology 20090401
Title: Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
Journal: Journal of neuro-oncology 20090401
Title: Possible leukemogenic potential of temozolomide.
Journal: Pediatric blood & cancer 20090401
Title: Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Journal: NeuroImage 20090401
Title: Opportunistic cytomegalovirus infection in a patient receiving temozolomide for treatment of malignant glioma.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090401
Title: NHERF-1: modulator of glioblastoma cell migration and invasion.
Journal: Neoplasia (New York, N.Y.) 20090401
Title: Hypersensitivity pneumonitis associated with the use of temozolomide.
Journal: The European respiratory journal 20090401
Title: BNIP3 (Bcl-2 19 kDa interacting protein) acts as transcriptional repressor of apoptosis-inducing factor expression preventing cell death in human malignant gliomas.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090401
Title: Use of temozolomide in aggressive pituitary tumors: case report.
Journal: Neurosurgery 20090401
Title: [Prognostic and predictive factors for gliomas in adults].
Journal: Bulletin du cancer 20090401
Title: Synchronous tonsil, gallbladder, and cardiac metastases without any other visceral metastases of malignant melanoma.
Journal: Onkologie 20090401
Title: Recent clinical and pathophysiological advances in non-functioning pituitary adenomas.
Journal: Hormone research 20090401
Title: Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.
Journal: British journal of cancer 20090324
Title: Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090315
Title: Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310
Title: Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310
Title: Long-term survival of patients with glioblastoma treated with radiotherapy and lomustine plus temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310
Title: Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310
Title: Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310
Title: Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.
Journal: British journal of cancer 20090310
Title: The side story of stem-like glioma cells.
Journal: Cell stem cell 20090306
Title: PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.
Journal: Cell stem cell 20090306
Title: Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways.
Journal: Purinergic signalling 20090301
Title: Association of preoperative depression and survival after resection of malignant brain astrocytoma.
Journal: Surgical neurology 20090301
Title: Tuberculosis in a patient on temozolomide: a case report.
Journal: Journal of neuro-oncology 20090301
Title: ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Journal: Journal of neuro-oncology 20090301
Title: Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.
Journal: Journal of neuro-oncology 20090301
Title: Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma.
Journal: Journal of neuro-oncology 20090301
Title: A multi-institutional phase II study on second-line Fotemustine chemotherapy in recurrent glioblastoma.
Journal: Journal of neuro-oncology 20090301
Title: Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme.
Journal: Journal of neurosurgery 20090301
Title: Exophytic giant cell glioblastoma of the medulla oblongata.
Journal: Journal of neurosurgery 20090301
Title: Association between hyperglycemia and survival in patients with newly diagnosed glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090301
Title: O(6)-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas: are progressive tumors potential candidates for temozolomide treatment?
Journal: Cancer 20090301
Title: Differential effect of imatinib and synergism of combination treatment with chemotherapeutic agents in malignant glioma cells.
Journal: Basic & clinical pharmacology & toxicology 20090301
Title: Inverse-electron-demand Diels-Alder reaction as a highly efficient chemoselective ligation procedure: synthesis and function of a BioShuttle for temozolomide transport into prostate cancer cells.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20090301
Title: Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells.
Journal: Cancer research 20090301
Title: [Evaluation of stability of temozolomide in solutions after opening the capsule].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090301
Title: Management of temozolomide toxicity by nurse practitioners in neuro-oncology.
Journal: Oncology nursing forum 20090301
Title: Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
Journal: Molecular cancer therapeutics 20090301
Title: Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide.
Journal: Cancer biology & therapy 20090301
Title: [Bilateral thalamic glioma in an adult: a case report and review of the literature].
Journal: No shinkei geka. Neurological surgery 20090301
Title: [Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas].
Journal: Bulletin du cancer 20090301
Title: [Biological basis of chemo-radiotherapy associations].
Journal: Bulletin du cancer 20090301
Title: [Predictive molecular pathological testing in the diagnosis of high-grade tumors of glial origin].
Journal: Magyar onkologia 20090301
Title: [Research and therapeutic trials on gliomas].
Journal: Soins; la revue de reference infirmiere 20090301
Title: Efficacy of temozolomide treatment in patients with high-grade glioma.
Journal: Anticancer research 20090301
Title: Primary CNS lymphoma.
Journal: Therapeutic advances in neurological disorders 20090301
Title: The context and potential of epigenetics in oncology.
Journal: British journal of cancer 20090224
Title: Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
Title: Integrating BRAF/MEK inhibitors into combination therapy for melanoma.
Journal: British journal of cancer 20090210
Title: Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells.
Journal: Biochemical and biophysical research communications 20090206
Title: Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture.
Journal: Investigational new drugs 20090201
Title: Accelerated hypofractionated intensity-modulated radiotherapy with concurrent and adjuvant temozolomide for patients with glioblastoma multiforme: a safety and efficacy analysis.
Journal: International journal of radiation oncology, biology, physics 20090201
Title: Topotecan enhances immune clearance of gliomas.
Journal: Cancer immunology, immunotherapy : CII 20090201
Title: Quality of life in low-grade glioma patients receiving temozolomide.
Journal: Neuro-oncology 20090201
Title: New (alternative) temozolomide regimens for the treatment of glioma.
Journal: Neuro-oncology 20090201
Title: Experience with irinotecan for the treatment of malignant glioma.
Journal: Neuro-oncology 20090201
Title: The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity.
Journal: Neuro-oncology 20090201
Title: Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20090201
Title: Concomitant (without adjuvant) temozolomide and radiation to treat glioblastoma: a retrospective study.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20090201
Title: Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090201
Title: A color-coded orthotopic nude-mouse treatment model of brain-metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis.
Journal: Cell proliferation 20090201
Title: Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines.
Journal: Molecular cancer therapeutics 20090201
Title: Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma.
Journal: Cell cycle (Georgetown, Tex.) 20090201
Title: Oligodendrogliomas: molecular biology and treatment.
Journal: The oncologist 20090201
Title: Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090201
Title: Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma.
Journal: Molecular cancer therapeutics 20090201
Title: Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
Journal: Acta neurochirurgica 20090201
Title: p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal.
Journal: Molecular cancer research : MCR 20090201
Title: Radiobiological evaluation and correlation with the local effect model (LEM) of carbon ion radiation therapy and temozolomide in glioblastoma cell lines.
Journal: International journal of radiation biology 20090201
Title: Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
Journal: British journal of cancer 20090127
Title: A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer.
Journal: British journal of cancer 20090127
Title: Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer.
Journal: Journal of medicinal chemistry 20090122
Title: [Microsurgical strategies of glioma located in lateral fissure area].
Journal: Zhonghua yi xue za zhi 20090120
Title: Genomic and molecular profiling predicts response to temozolomide in melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090115
Title: In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090115
Title: Activation of KATP channels increases anticancer drug delivery to brain tumors and survival.
Journal: European journal of pharmacology 20090114
Title: Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.
Journal: Brain pathology (Zurich, Switzerland) 20090101
Title: A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090101
Title: Near-infrared optical imaging in glioblastoma xenograft with ligand-targeting alpha 3 integrin.
Journal: European journal of nuclear medicine and molecular imaging 20090101
Title: Hypofractionated radiotherapy followed by adjuvant chemotherapy with temozolomide in elderly patients with glioblastoma.
Journal: Journal of neuro-oncology 20090101
Title: Aberrant MGMT (O6-methylguanine-DNA methyltransferase) promoter methylation in choroid plexus tumors.
Journal: Journal of neuro-oncology 20090101
Title: Comparative analysis of temozolomide (TMZ) versus 1,3-bis (2-chloroethyl)-1 nitrosourea (BCNU) in newly diagnosed glioblastoma multiforme (GBM) patients.
Journal: Journal of neuro-oncology 20090101
Title: Bone marrow transplantation for severe aplastic anemia secondary to temozolomide.
Journal: Journal of neuro-oncology 20090101
Title: Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.
Journal: DNA repair 20090101
Title: Cryopreservation of neurospheres derived from human glioblastoma multiforme.
Journal: Stem cells (Dayton, Ohio) 20090101
Title: Independent association of extent of resection with survival in patients with malignant brain astrocytoma.
Journal: Journal of neurosurgery 20090101
Title: MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma.
Journal: European journal of cancer (Oxford, England : 1990) 20090101
Title: Absence of MGMT promoter methylation in endometrial cancer.
Journal: Gynecologic oncology 20090101
Title: Treatment of Nelson's syndrome with temozolomide.
Journal: European journal of endocrinology 20090101
Title: Management of aggressive pituitary adenomas: current treatment strategies.
Journal: Pituitary 20090101
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Journal: Brain pathology (Zurich, Switzerland) 20090101
Title: [Diagnostic and treatment delays do not modify the treatment outcome of patients with multiform glioblastoma].
Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20090101
Title: A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients.
Journal: Cancer research 20090101
Title: Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090101
Title: O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090101
Title: Whole brain radiotherapy with radiosensitizer for brain metastases.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Chemotherapeutic treatment efficacy and sensitivity are increased by adjuvant alternating electric fields (TTFields).
Journal: BMC medical physics 20090101
Title: Continuous administration of daily low-dose temozolomide in pretreated patients with advanced non-small cell lung cancer: a phase II study.
Journal: Oncology 20090101
Title: HMGB1 mediates endogenous TLR2 activation and brain tumor regression.
Journal: PLoS medicine 20090101
Title: Recent approaches to improve the antitumor efficacy of temozolomide.
Journal: Current medicinal chemistry 20090101
Title: Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
Journal: Journal of translational medicine 20090101
Title: Encountering and advancing through antiangiogenesis therapy for gliomas.
Journal: Current pharmaceutical design 20090101
Title: Nodular melanoma presenting with rapid progression and widespread metastases: a case report.
Journal: Journal of medical case reports 20090101
Title: Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation.
Journal: BMC genomics 20090101
Title: Modulation of the efficacy of temozolomide and dacarbazine melanoma treatment by DNA-repair factors in vivo and in vitro.
Journal: International journal of clinical pharmacology and therapeutics 20090101
Title: The potential role and application of PARP inhibitors in cancer treatment.
Journal: British medical bulletin 20090101
Title: Localized BCNU chemotherapy and the multimodal management of malignant glioma.
Journal: Current medical research and opinion 20090101
Title: The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.
Journal: PloS one 20090101
Title: Autophagy pathways in glioblastoma.
Journal: Methods in enzymology 20090101
Title: Nimustine (ACNU) plus teniposide (VM26) in recurrent glioblastoma.
Journal: Oncology 20090101
Title: Brain metastasis from an unknown primary, or primary brain tumour? A diagnostic dilemma.
Journal: Current oncology (Toronto, Ont.) 20090101
Title: Multiple pilomatricomas and gliomatosis cerebri--a new association?
Journal: Pediatric dermatology 20090101
Title: Loss of heterozygosity of TRIM3 in malignant gliomas.
Journal: BMC cancer 20090101
Title: A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells.
Journal: Journal of neuroinflammation 20090101
Title: Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.
Journal: PloS one 20090101
Title: Stereotactic radiosurgery for glioblastoma: retrospective analysis.
Journal: Radiation oncology (London, England) 20090101
Title: Radiation therapy.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20090101
Title: Other experimental therapies for glioma.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20090101
Title: Molecular neuropathology of gliomas.
Journal: International journal of molecular sciences 20090101
Title: Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation.
Journal: BMC cancer 20090101
Title: Current concepts and newer developments in the treatment of malignant gliomas.
Journal: Indian journal of cancer 20090101
Title: Evidence-based adjuvant therapy for gliomas: current concepts and newer developments.
Journal: Indian journal of cancer 20090101
Title: PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment.
Journal: PloS one 20090101
Title: ACTH-producing carcinoma of the pituitary with refractory Cushing's Disease and hepatic metastases: a case report and review of the literature.
Journal: World journal of surgical oncology 20090101
Title: Effects of fotemustine or dacarbasine on a melanoma cell line pretreated with therapeutic proton irradiation.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
Journal: PloS one 20090101
Title: Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.
Journal: Advances and technical standards in neurosurgery 20090101
Title: Breast cancer therapy for BRCA1 carriers: moving towards platinum standard?
Journal: Hereditary cancer in clinical practice 20090101
Title: Current concepts in stereotactic radiosurgery - a neurosurgical and radiooncological point of view.
Journal: European journal of medical research 20090101
Title: Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
Journal: Chemotherapy 20090101
Title: Primary diffuse leptomeningeal gliomatosis.
Journal: European neurology 20090101
Title: The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies.
Journal: PloS one 20090101
Title: CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
Journal: Journal of translational medicine 20090101
Title: Management of malignant melanoma: best practices.
Journal: Journal of cutaneous medicine and surgery 20090101
Title: Temozolomide and cisplatin in relapsed/refractory acute leukemia.
Journal: Journal of hematology & oncology 20090101
Title: Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.
Journal: PloS one 20090101
Title: Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy.
Journal: American journal of clinical dermatology 20090101
Title: High specificity of quantitative methylation-specific PCR analysis for MGMT promoter hypermethylation detection in gliomas.
Journal: Journal of biomedicine & biotechnology 20090101
Title: Temozolomide: a safe and effective treatment for malignant digestive endocrine tumors.
Journal: Neuroendocrinology 20090101
Title: Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.
Journal: PloS one 20090101
Title: Modulation of angiogenic and inflammatory response in glioblastoma by hypoxia.
Journal: PloS one 20090101
Title: KIF11 inhibition for glioblastoma treatment: reason to hope or a struggle with the brain?
Journal: BMC cancer 20090101
Title: Outcome of newly diagnosed glioblastoma patients treated by radiotherapy plus concomitant and adjuvant temozolomide: a long-term analysis.
Journal: Tumori 20090101
Title: Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations.
Journal: Journal of translational medicine 20090101
Title: Retrospective analysis of treatment outcome in 315 patients with oligodendroglial brain tumors.
Journal: BMC neurology 20090101
Title: Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy.
Journal: PloS one 20090101
Title: Vorinostat in solid and hematologic malignancies.
Journal: Journal of hematology & oncology 20090101
Title: Genomic advances and their impact on clinical trial design.
Journal: Genome medicine 20090101
Title: ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside.
Journal: Journal of hematology & oncology 20090101
Title: Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma.
Journal: BMC cancer 20090101
Title: Prognostic factors other than the performance status and age for glioblastoma multiforme: a single-institution experience.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101
Title: Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.
Journal: PloS one 20090101
Title: MGMT promoter hypermethylation in a series of 104 glioblastomas.
Journal: Cancer genomics & proteomics 20090101
Title: Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy.
Journal: PloS one 20090101
Title: Diffuse anorectal melanoma; review of the current diagnostic and treatment aspects based on a case report.
Journal: World journal of surgical oncology 20090101
Title: Three-dimensional conformal radiotherapy, temozolomide chemotherapy, and high-dose fractionated stereotactic boost in a protocol-driven, postoperative treatment schedule for high-grade gliomas.
Journal: Tumori 20090101
Title: Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy.
Journal: Molecular cancer 20090101
Title: Current available therapies and future directions in the treatment of malignant gliomas.
Journal: Biologics : targets & therapy 20090101
Title: Long-term pegylated interferon-alpha and its potential in the treatment of melanoma.
Journal: Biologics : targets & therapy 20090101
Title: Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors.
Journal: Journal of translational medicine 20090101
Title: RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study.
Journal: BMC cancer 20090101
Title: Transcriptome and proteome analyses of adaptive responses to methyl methanesulfonate in Escherichia coli K-12 and ada mutant strains.
Journal: BMC microbiology 20090101
Title: Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer.
Journal: Breast cancer research : BCR 20090101
Title: Transcriptional control of Flt3 ligand targeted by fluorouracil-induced Egr-1 promoter in hematopoietic damage.
Journal: Journal of biomedical science 20090101
Title: Current use and potential role of bevacizumab in the treatment of gastrointestinal cancers.
Journal: Biologics : targets & therapy 20090101
Title: Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells.
Journal: Molecular cancer 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays.
Journal: Genome biology 20090101
Title: Immunological considerations of modern animal models of malignant primary brain tumors.
Journal: Journal of translational medicine 20090101
Title: Do neurooncological patients and their significant others agree on quality of life ratings?
Journal: Health and quality of life outcomes 20090101
Title: Intralesional lymphokine-activated killer cells as adjuvant therapy for primary glioblastoma.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20090101
Title: GSK3beta regulates differentiation and growth arrest in glioblastoma.
Journal: PloS one 20090101
Title: Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells.
Journal: Radiation oncology (London, England) 20090101
Title: Gliomatosis cerebri type II: two case reports.
Journal: Journal of medical case reports 20090101
Title: Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults.
Journal: BMC cancer 20090101
Title: Insights into gliomagenesis: systems biology unravels key pathways.
Journal: Genome medicine 20090101
Title: Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme.
Journal: Annals of clinical and laboratory science 20090101
Title: Continuous 5-fluorouracil infusion plus long acting octreotide in advanced well-differentiated neuroendocrine carcinomas. A phase II trial of the Piemonte oncology network.
Journal: BMC cancer 20090101
Title: Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.
Journal: PloS one 20090101
Title: Management of advanced stage uterine sarcomas: a bone of contention.
Journal: European journal of gynaecological oncology 20090101
Title: Preparation and the influencing factors of timozolomide liposomes.
Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20090101
Title: yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients.
Journal: Journal of translational medicine 20090101
Title: Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations.
Journal: PloS one 20090101
Title: Integrated-boost IMRT or 3-D-CRT using FET-PET based auto-contoured target volume delineation for glioblastoma multiforme--a dosimetric comparison.
Journal: Radiation oncology (London, England) 20090101
Title: Metastatic Melanoma presenting 24 years after surgical resection: a case report and review of the literature.
Journal: Cases journal 20090101
Title: High-resolution flow cytometry: a suitable tool for monitoring aneuploid prostate cancer cells after TMZ and TMZ-BioShuttle treatment.
Journal: International journal of medical sciences 20090101
Title: [Glioblastoma treatment in 2010].
Journal: Revue medicale de Bruxelles 20090101
Title: Introduction of hypermatrix and operator notation into a discrete mathematics simulation model of malignant tumour response to therapeutic schemes in vivo. Some operator properties.
Journal: Cancer informatics 20090101
Title: Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme.
Journal: BMC cancer 20090101
Title: Recursive partitioning analysis of prognostic factors in WHO grade III glioma patients treated with radiotherapy or radiotherapy plus chemotherapy.
Journal: BMC cancer 20090101
Title: Effect of temozolomide in a patient with recurring oncocytic gonadotrophic pituitary adenoma.
Journal: Hormones (Athens, Greece) 20090101
Title: Histidine-rich glycoprotein can prevent development of mouse experimental glioblastoma.
Journal: PloS one 20090101
Title: Targeted therapy in melanoma.
Journal: Biologics : targets & therapy 20090101
Title: Antiangiogenic therapy in the treatment of recurrent medulloblastoma in the adult: case report and review of the literature.
Journal: Journal of oncology 20090101
Title: Potential Role of Thymosin-alpha1 Adjuvant Therapy for Glioblastoma.
Journal: Journal of oncology 20090101
Title: A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy.
Journal: Clinical neurosurgery 20090101
Title: In Silico Enhanced Restriction Enzyme Based Methylation Analysis of the Human Glioblastoma Genome Using Agilent 244K CpG Island Microarrays.
Journal: Frontiers in neuroscience 20090101
Title: Malignant gastrointestinal melanoma with an unknown primary.
Journal: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20090101
Title: Role of palliative radiotherapy in brain metastases.
Journal: Indian journal of palliative care 20090101
Title: Targeted therapy in the treatment of malignant gliomas.
Journal: OncoTargets and therapy 20090101
Title: Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports.
Journal: Indian journal of palliative care 20090101
Title: Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas.
Journal: Core evidence 20090101
Title: New therapies for recurrent glioblastomas.
Journal: F1000 medicine reports 20090101
Title: Treated choroidal melanoma with late metastases to the contralateral orbit.
Journal: Clinical medicine. Pathology 20090101
Title: Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations.
Journal: Cancer management and research 20090101
Title: Gene therapy in thalassemia and hemoglobinopathies.
Journal: Mediterranean journal of hematology and infectious diseases 20090101
Title: Salvage therapy with temozolomide for recurrent or progressive high-grade gliomas refractory to ACNU [1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride].
Journal: Molecular medicine reports 20090101
Title: Current management of metastatic melanoma.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081215
Title: p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
Journal: Cancer research 20081215
Title: Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20081215
Title: Stemming cancer: functional genomics of cancer stem cells in solid tumors.
Journal: Stem cell reviews 20081201
Title: Phase I trial of weekly docetaxel and daily temozolomide in patients with metastatic disease.
Journal: Investigational new drugs 20081201
Title: Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy.
Journal: European journal of radiology 20081201
Title: A novel tool to analyze MRI recurrence patterns in glioblastoma.
Journal: Neuro-oncology 20081201
Title: Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas.
Journal: Journal of neuro-oncology 20081201
Title: Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.
Journal: Analytical biochemistry 20081201
Title: Silencing DNA methyltransferase (DNMT) enhances glioma chemosensitivity.
Journal: Oligonucleotides 20081201
Title: Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib.
Journal: Nature clinical practice. Oncology 20081201
Title: Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081201
Title: Differential effects of imatinib mesylate against uveal melanoma in vitro and in vivo.
Journal: Melanoma research 20081201
Title: Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens: is the survival really so impressive?: in regard to Combs et al. (Int J Radiat Oncol Biol Phys 2008;71:999-1005).
Journal: International journal of radiation oncology, biology, physics 20081201
Title: Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20081201
Title: Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20081201
Title: Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
Journal: Neoplasia (New York, N.Y.) 20081201
Title: Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells.
Journal: Molecular cancer therapeutics 20081201
Title: IFN-beta sensitizes neuroblastoma to the antitumor activity of temozolomide by modulating O6-methylguanine DNA methyltransferase expression.
Journal: Molecular cancer therapeutics 20081201
Title: Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma.
Journal: Surgical neurology 20081201
Title: Pituitary carcinoma presenting with multiple metastases: case report.
Journal: Journal of child neurology 20081201
Title: Prospective trial of gross-total resection with Gliadel wafers followed by early postoperative Gamma Knife radiosurgery and conformal fractionated radiotherapy as the initial treatment for patients with radiographically suspected, newly diagnosed glioblastoma multiforme.
Journal: Journal of neurosurgery 20081201
Title: Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
Journal: Acta neurologica Belgica 20081201
Title: Systems biology: a therapeutic target for tumor therapy.
Journal: Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201
Title: Rituximab in the treatment of non-Hodgkin's lymphoma.
Journal: Biologics : targets & therapy 20081201
Title: Therapeutic vaccines for malignant brain tumors.
Journal: Biologics : targets & therapy 20081201
Title: Novel microtubule-targeting agents - the epothilones.
Journal: Biologics : targets & therapy 20081201
Title: Proapoptotic receptor agonists, targeted radionuclide therapy, and the treatment of central nervous system malignancies: in regard to Fiveash et Al. (Int J Radiat Oncol Biol Phys 2008;71:507-516).
Journal: International journal of radiation oncology, biology, physics 20081115
Title: Antitumor efficacy testing in rodents.
Journal: Journal of the National Cancer Institute 20081105
Title: Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy.
Journal: Journal of neuro-oncology 20081101
Title: Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
Journal: Neurological research 20081101
Title: Disseminated salmonellosis in a patient treated with temozolomide.
Journal: The Journal of infection 20081101
Title: Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20081101
Title: Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.
Journal: Cancer 20081101
Title: Novel bone cancer drugs: investigational agents and control paradigms for primary bone sarcomas (Ewing's sarcoma and osteosarcoma).
Journal: Expert opinion on investigational drugs 20081101
Title: Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.
Journal: Current medical research and opinion 20081101
Title: Characterization of a side population of astrocytoma cells in response to temozolomide.
Journal: Journal of neurosurgery 20081101
Title: Pathway targets to explore in the treatment of non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081101
Title: Association between response to primary treatments and MGMT status in glioblastoma.
Journal: Expert review of anticancer therapy 20081101
Title: Treatment-related myelodysplastic syndrome after temozolomide use in a child: first report.
Journal: Journal of pediatric hematology/oncology 20081101
Title: Methylation status of MGMT gene promoter in meningiomas.
Journal: Cancer genetics and cytogenetics 20081101
Title: Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide.
Journal: Molecular cancer therapeutics 20081101
Title: Erythropoietin augments survival of glioma cells after radiation and temozolomide.
Journal: International journal of radiation oncology, biology, physics 20081101
Title: Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20081101
Title: Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor.
Journal: PLoS biology 20081101
Title: 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.
Journal: Journal of medicinal chemistry 20081023
Title: Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020
Title: An enzyme-linked immunosorbent poly(ADP-ribose) polymerase biomarker assay for clinical trials of PARP inhibitors.
Journal: Analytical biochemistry 20081015
Title: Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the 'rescue' approach.
Journal: Cancer 20081015
Title: Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study.
Journal: Cancer 20081015
Title: DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081010
Title: Temozolomide for high grade glioma.
Journal: The Cochrane database of systematic reviews 20081008
Title: Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
Journal: British journal of cancer 20081007
Title: DNA repair and cancer stem-like cells--potential partners in glioma drug resistance?
Journal: Cancer treatment reviews 20081001
Title: Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide.
Journal: Pediatric blood & cancer 20081001
Title: A phase 2 trial of sequential temozolomide chemotherapy followed by high-dose interleukin 2 immunotherapy for metastatic melanoma.
Journal: Cancer 20081001
Title: Current clinical and research approaches to optimizing regional chemotherapy: novel strategies generated through a better understanding of drug pharmacokinetics, drug resistance, and the development of clinically relevant animal models.
Journal: Surgical oncology clinics of North America 20081001
Title: Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
Journal: Anti-cancer drugs 20081001
Title: Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma.
Journal: International journal of radiation oncology, biology, physics 20081001
Title: PARP inhibitors and cancer therapy - early results and potential applications.
Journal: The British journal of radiology 20081001
Title: A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study).
Journal: Japanese journal of clinical oncology 20081001
Title: Potentiation of temozolomide cytotoxicity by poly(ADP)ribose polymerase inhibitor ABT-888 requires a conversion of single-stranded DNA damages to double-stranded DNA breaks.
Journal: Molecular cancer research : MCR 20081001
Title: Designer therapies for glioblastoma multiforme.
Journal: Annals of the New York Academy of Sciences 20081001
Title: Quality of life in brain metastases radiation trials: a literature review.
Journal: Current oncology (Toronto, Ont.) 20081001
Title: Engineering of clinical glioma treatment: prediction of pro-invasive molecular events in treated gliomas.
Journal: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 20081001
Title: [Orthogonal experiments for optimizing the formulation and preparation conditions of temozolomide solid lipid nanoparticles].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20081001
Title: The outcomes of concomitant chemoradiotherapy followed by adjuvant chemotherapy with temozolomide for newly diagnosed high grade gliomas : the preliminary results of single center prospective study.
Journal: Journal of Korean Neurosurgical Society 20081001
Title: Survival from brain tumours in England and Wales up to 2001.
Journal: British journal of cancer 20080923
Title: Non-Hodgkin's lymphoma in patients with glioma treated with temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080920
Title: The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling.
Journal: Oncogene 20080904
Title: Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?
Journal: British journal of cancer 20080902
Title: Phase II trial of imatinib mesylate in patients with metastatic melanoma.
Journal: British journal of cancer 20080902
Title: Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
Journal: Surgical neurology 20080901
Title: Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
Journal: Journal of neuro-oncology 20080901
Title: Relationship of glioblastoma multiforme to the lateral ventricles predicts survival following tumor resection.
Journal: Journal of neuro-oncology 20080901
Title: A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
Journal: Journal of neuro-oncology 20080901
Title: Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas.
Journal: Journal of neuro-oncology 20080901
Title: CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma.
Journal: Journal of neuro-oncology 20080901
Title: Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma.
Journal: International journal of cancer 20080901
Title: Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
Journal: Gene therapy 20080901
Title: Temozolomide for recurrent low-grade spinal cord gliomas in adults.
Journal: Cancer 20080901
Title: Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080901
Title: Low-grade glioma: a challenge in therapeutic options: the role of radiotherapy.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080901
Title: [Alveolo-interstitial pneumonia due to Temozolamide].
Journal: Revue des maladies respiratoires 20080901
Title: Invasive tumor cells and prognosis in a selected population of patients with glioblastoma multiforme.
Journal: Cancer 20080815
Title: The development of xenograft glioblastoma implants in nude mice brain.
Journal: Journal of medicine and life 20080815
Title: Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080801
Title: Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability.
Journal: International journal of radiation oncology, biology, physics 20080801
Title: Glioblastoma in adults.
Journal: Critical reviews in oncology/hematology 20080801
Title: Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080801
Title: Toxicity from chemoradiotherapy in older patients with glioblastoma multiforme.
Journal: Journal of neuro-oncology 20080801
Title: Low grade astrocytoma presenting with visual loss.
Journal: Journal of neuro-oncology 20080801
Title: Cryptococcal meningitis in patients with glioma: a report of two cases.
Journal: Journal of neuro-oncology 20080801
Title: Multifocal glioblastoma multiforme with synchronous spontaneous hemorrhage: case report.
Journal: Journal of neuro-oncology 20080801
Title: Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide.
Journal: Molecular pharmacology 20080801
Title: Phase I safety study of escalating doses of atrasentan in adults with recurrent malignant glioma.
Journal: Neuro-oncology 20080801
Title: A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood.
Journal: Neuro-oncology 20080801
Title: Mechanisms of disease: temozolomide and glioblastoma--look to the future.
Journal: Nature clinical practice. Oncology 20080801
Title: Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma.
Journal: Neuro-oncology 20080801
Title: Different initial steps of apoptosis induced by two types of antineoplastic drugs.
Journal: Biochemical pharmacology 20080801
Title: Increased survivin expression confers chemoresistance to tumor-associated endothelial cells.
Journal: The American journal of pathology 20080801
Title: Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080801
Title: Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
Journal: Cancer research 20080801
Title: [Glioblastoma multiforme developing separately from the initial lesion 9 years after successful treatment for gliomatosis cerebri: a case report].
Journal: No shinkei geka. Neurological surgery 20080801
Title: Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Journal: Molecular cancer research : MCR 20080801
Title: Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.
Journal: Archivum immunologiae et therapiae experimentalis 20080801
Title: The economic impact on families when a child is diagnosed with cancer.
Journal: Current oncology (Toronto, Ont.) 20080801
Title: Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas.
Journal: Neurosurgery 20080801
Title: Optimizing radiotherapy of brain tumours by a combination of temozolomide & lonidamine.
Journal: The Indian journal of medical research 20080801
Title: In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
Journal: British journal of cancer 20080722
Title: Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens.
Journal: International journal of radiation oncology, biology, physics 20080715
Title: Incidence of early pseudo-progression in a cohort of malignant glioma patients treated with chemoirradiation with temozolomide.
Journal: Cancer 20080715
Title: Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer.
Journal: Bioorganic & medicinal chemistry 20080715
Title: Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent.
Journal: Bioorganic & medicinal chemistry letters 20080715
Title: Temozolomide preferentially depletes cancer stem cells in glioblastoma.
Journal: Cancer research 20080715
Title: Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis.
Journal: British journal of cancer 20080708
Title: Polymorphs and polymorphic cocrystals of temozolomide.
Journal: Chemistry, an Asian journal 20080707
Title: Temozolomide in combination with fotemustine in patients with metastatic melanoma.
Journal: Cancer chemotherapy and pharmacology 20080701
Title: Two metachronous tumors induced by radiation therapy: case report and review of the literature.
Journal: Journal of neuro-oncology 20080701
Title: A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.
Journal: Journal of neuro-oncology 20080701
Title: Expression of integrin alphavbeta3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature.
Journal: Brain pathology (Zurich, Switzerland) 20080701
Title: AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
Journal: Molecular pharmacology 20080701
Title: Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.
Journal: Molecular pharmacology 20080701
Title: Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience.
Journal: Anti-cancer drugs 20080701
Title: Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.
Journal: The Journal of molecular diagnostics : JMD 20080701
Title: Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction.
Journal: Oncology reports 20080701
Title: Low-grade gliomas in adults.
Journal: Current treatment options in neurology 20080701
Title: Glioblastoma multiforme.
Journal: Current treatment options in neurology 20080701
Title: Anaplastic oligodendroglioma.
Journal: Current treatment options in neurology 20080701
Title: Metastatic melanoma: scientific rationale for sorafenib treatment and clinical results.
Journal: Onkologie 20080701
Title: Impact of p53 status to response of temozolomide in low MGMT expression glioblastomas: preliminary results.
Journal: Neurological research 20080701
Title: Major Advances in the Treatment of Cancer: What does a Non-Oncologist need to know?
Journal: Sultan Qaboos University medical journal 20080701
Title: Stem cell-related 'self-renewal' signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620
Title: Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study.
Journal: British journal of cancer 20080603
Title: Oligodendroglioma.
Journal: Critical reviews in oncology/hematology 20080601
Title: Evidence of galectin-1 involvement in glioma chemoresistance.
Journal: Toxicology and applied pharmacology 20080601
Title: Complete response after one cycle of temozolomide in an elderly patient with glioblastoma and poor performance status.
Journal: Journal of neuro-oncology 20080601
Title: Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.
Journal: Neuro-oncology 20080601
Title: Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
Journal: Neuro-oncology 20080601
Title: FDG-PET imaging for the evaluation of antiglioma agents in a rat model.
Journal: Neuro-oncology 20080601
Title: Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.
Journal: European journal of cancer (Oxford, England : 1990) 20080601
Title: Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.
Journal: International journal of radiation oncology, biology, physics 20080601
Title: Management of malignant glioma--quo vadis?
Journal: Onkologie 20080601
Title: Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment.
Journal: Onkologie 20080601
Title: The role of temozolomide in newly-diagnosed glioblastoma multiforme.
Journal: British journal of neurosurgery 20080601
Title: [Current topics of treatment for glioma and mechanism of drug resistance].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20080601
Title: Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance.
Journal: Biologics : targets & therapy 20080601
Title: A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.
Journal: British journal of cancer 20080520
Title: Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment.
Journal: Cancer research 20080515
Title: Phase II study of extended-dose temozolomide in patients with melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080510
Title: Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
Journal: Cancer chemotherapy and pharmacology 20080501
Title: Up-regulation of vimentin expression in low-density malignant glioma cells as immediate and late effects under irradiation and temozolomide treatment.
Journal: Amino acids 20080501
Title: Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model.
Journal: Journal of neuro-oncology 20080501
Title: The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma.
Journal: Journal of neuro-oncology 20080501
Title: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.
Journal: Journal of neuro-oncology 20080501
Title: Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
Journal: Journal of neuro-oncology 20080501
Title: Solid lipid nanoparticles of temozolomide: potential reduction of cardial and nephric toxicity.
Journal: International journal of pharmaceutics 20080501
Title: Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.
Journal: Autophagy 20080501
Title: The influence of low-grade glioma on resting state oscillatory brain activity: a magnetoencephalography study.
Journal: Journal of neuro-oncology 20080501
Title: Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?
Journal: Journal of neuro-oncology 20080501
Title: Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma.
Journal: Cancer 20080501
Title: Focus on FOCIS: interleukin 2 treatment associated autoimmunity.
Journal: Clinical immunology (Orlando, Fla.) 20080501
Title: Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
Journal: Journal of neuropathology and experimental neurology 20080501
Title: Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
Journal: Cancer investigation 20080501
Title: MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080501
Title: Temozolomide-mediated radiosensitization of human glioma cells in a zebrafish embryonic system.
Journal: Cancer research 20080501
Title: Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.
Journal: The Lancet. Oncology 20080501
Title: Adjuvant temozolomide: how long and how much?
Journal: Expert review of anticancer therapy 20080501
Title: Combi-targeting concept: an optimized single-molecule dual-targeting model for the treatment of chronic myelogenous leukemia.
Journal: Molecular cancer therapeutics 20080501
Title: [On the occasion of my retirement as head of the Neurochirurgische Universitätsklinik Zürich--changing aspects of treatment modality in modern neurosurgery and of neuroscience research. Presentation of our experience and historical backgrounds].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20080501
Title: When temozolomide alone fails: adding procarbazine in salvage therapy of glioma.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080501
Title: A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.
Journal: British journal of cancer 20080422
Title: Noninvasive imaging of apoptosis and its application in cancer therapeutics.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080415
Title: Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development.
Journal: Cancer cell 20080408
Title: A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation.
Journal: Cancer chemotherapy and pharmacology 20080401
Title: Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients.
Journal: Journal of neuro-oncology 20080401
Title: An orthotopic skull base model of malignant meningioma.
Journal: Brain pathology (Zurich, Switzerland) 20080401
Title: Temozolomide plus pegylated interferon alfa-2b as first-line treatment for stage IV melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group (DeCOG).
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080401
Title: Brain and leptomeningeal metastases from cutaneous melanoma: survival outcomes based on clinical features.
Journal: Neuro-oncology 20080401
Title: A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.
Journal: Neuro-oncology 20080401
Title: Temozolomide associated with PEG-interferon in patients with metastatic melanoma: a multicenter prospective phase I/II study.
Journal: Melanoma research 20080401
Title: Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
Journal: Melanoma research 20080401
Title: The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma.
Journal: Oncology reports 20080401
Title: Translational research in glioblastoma multiforme: molecular criteria for patient selection.
Journal: Future oncology (London, England) 20080401
Title: [Genetic diagnoses and individualized treatment of gliomas].
Journal: No shinkei geka. Neurological surgery 20080401
Title: Anaplastic astrocytomas: biology and treatment.
Journal: Expert review of neurotherapeutics 20080401
Title: A rare case of melanoma recurring as subcutaneous metastatic melanoma with overlying ecchymoses.
Journal: Archives of dermatology 20080401
Title: A multivariate analysis of patients with glioma: a treatment outcome and prognostic factor for survival.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080401
Title: Cerebellar glioblastoma multiforme in an adult.
Journal: Journal of Korean Neurosurgical Society 20080401
Title: Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients.
Journal: International journal of radiation oncology, biology, physics 20080315
Title: MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome.
Journal: International journal of cancer 20080315
Title: Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study.
Journal: Cancer 20080315
Title: Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
Journal: Pediatric blood & cancer 20080301
Title: A phase II trial of vinorelbine and intensive temozolomide for patients with recurrent or progressive brain metastases.
Journal: Journal of neuro-oncology 20080301
Title: Fixed dose-rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: a dose-finding study.
Journal: Journal of neuro-oncology 20080301
Title: Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.
Journal: Journal of neuro-oncology 20080301
Title: Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas.
Journal: Cancer 20080301
Title: Temozolomide-induced desquamative skin rash in a patient with metastatic melanoma.
Journal: Pharmacotherapy 20080301
Title: An investigation of boron neutron capture therapy for recurrent glioblastoma multiforme.
Journal: Acta neurologica Scandinavica 20080301
Title: Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080301
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Journal: Cancer research 20080301
Title: Emerging drugs for malignant glioma.
Journal: Expert opinion on emerging drugs 20080301
Title: [Report of the 10th Annual Meeting of the Chinese society of Clinical Oncology].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080301
Title: [Temozolomide: Temodal].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20080301
Title: Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
Journal: Expert review of anticancer therapy 20080301
Title: Glioblastoma in a patient with a hereditary cancer syndrome.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080301
Title: [The sodium pump could constitute a new target to combat glioblastomas].
Journal: Bulletin du cancer 20080301
Title: Recent advances in blood-brain barrier disruption as a CNS delivery strategy.
Journal: The AAPS journal 20080301
Title: Clinical uses of GM-CSF, a critical appraisal and update.
Journal: Biologics : targets & therapy 20080301
Title: Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080220
Title: Genetic markers predictive of chemosensitivity and outcome in gliomatosis cerebri.
Journal: Neurology 20080219
Title: Clinical pharmacology of cancer therapies in older adults.
Journal: British journal of cancer 20080212
Title: MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy.
Journal: Acta neuropathologica 20080201
Title: Defining the standard of care for high-grade glioma--a NICE deal for patients.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20080201
Title: In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080201
Title: Targeting the epidermal growth factor receptor in high-grade astrocytomas.
Journal: Current treatment options in oncology 20080201
Title: [Chemotherapy for brain tumors in adult patients].
Journal: Der Nervenarzt 20080201
Title: [Recent advances in chemotherapy for malignant gliomas].
Journal: No shinkei geka. Neurological surgery 20080201
Title: Natural history and management of brainstem gliomas in adults. A retrospective Italian study.
Journal: Journal of neurology 20080201
Title: Midline glioblastoma multiforme with bilateral symmetric cysts.
Journal: Journal of Korean Neurosurgical Society 20080201
Title: Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
Journal: Brain research 20080110
Title: Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
Journal: Cancer immunology, immunotherapy : CII 20080101
Title: Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.
Journal: International journal of radiation oncology, biology, physics 20080101
Title: Prognostic factors for survival in 676 consecutive patients with newly diagnosed primary glioblastoma.
Journal: Neuro-oncology 20080101
Title: Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
Journal: Surgical neurology 20080101
Title: Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
Journal: Neuro-oncology 20080101
Title: Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3.
Journal: The Lancet. Oncology 20080101
Title: Cannabinoids as potential new therapy for the treatment of gliomas.
Journal: Expert review of neurotherapeutics 20080101
Title: Temozolomide and resistant glioma cells.
Journal: Journal of neurosurgery 20080101
Title: Nomograms as clinicobiological predictors of survival in glioblastoma.
Journal: The Lancet. Oncology 20080101
Title: Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.
Journal: Cerebrospinal fluid research 20080101
Title: Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.
Journal: Molecular cancer therapeutics 20080101
Title: Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.
Journal: PLoS medicine 20080101
Title: Incorporating molecular tools into early-stage clinical trials.
Journal: PLoS medicine 20080101
Title: Induction of gliosarcoma and atypical meningioma 13 years after radiotherapy of residual pilocytic astrocytoma in childhood.
Journal: Pediatric neurosurgery 20080101
Title: [Treatment of marignant brain tumor: today and tomorrow].
Journal: No shinkei geka. Neurological surgery 20080101
Title: [Molecular genetic analysis for malignant gliomas: clinical implications and future directions].
Journal: No shinkei geka. Neurological surgery 20080101
Title: Overcoming therapeutic resistance in malignant gliomas: current practices and future directions.
Journal: Cancer treatment and research 20080101
Title: Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.
Journal: Retrovirology 20080101
Title: Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
Journal: Pathology, research and practice 20080101
Title: A multicenter cohort study of dose-dense temozolomide (21 of 28 days) for the treatment of recurrent anaplastic astrocytoma or oligoastrocytoma.
Journal: Cancer investigation 20080101
Title: An integrative genomic and epigenomic approach for the study of transcriptional regulation.
Journal: PloS one 20080101
Title: Advanced cutaneous malignant melanoma: a systematic review of economic and quality-of-life studies.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101
Title: Dihydroartemisinin potentiates the cytotoxic effect of temozolomide in rat C6 glioma cells.
Journal: Pharmacology 20080101
Title: Morphologically and immunohistochemically undifferentiated gastric neoplasia in a patient with multiple metastatic malignant melanomas: a case report.
Journal: Journal of medical case reports 20080101
Title: Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma.
Journal: Journal of translational medicine 20080101
Title: Extra central nervous system metastases from cerebral glioblastoma multiforme in elderly patients. Clinico-pathological remarks on our series of seven cases and critical review of the literature.
Journal: Tumori 20080101
Title: Increased seroreactivity to glioma-expressed antigen 2 in brain tumor patients under radiation.
Journal: PloS one 20080101
Title: Highly proliferative neuroendocrine carcinoma - influence of radiotherapy fractionation on tumor response.
Journal: Radiation oncology (London, England) 20080101
Title: A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors.
Journal: Cancer cell international 20080101
Title: Congenital glioblastoma multiforme: case report and review of the literature.
Journal: Pediatric neurosurgery 20080101
Title: PPARgamma in Neuroblastoma.
Journal: PPAR research 20080101
Title: Fibrin sealant does not decrease seroma output or time to drain removal following inguino-femoral lymph node dissection in melanoma patients: a randomized controlled trial (NCT00506311).
Journal: World journal of surgical oncology 20080101
Title: [Therapeutic strategies for the management of gliomas].
Journal: Revue neurologique 20080101
Title: Outpatient and home chemotherapy with novel local control strategies in desmoplastic small round cell tumor.
Journal: Sarcoma 20080101
Title: A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier.
Journal: PloS one 20080101
Title: PPARgamma and MEK Interactions in Cancer.
Journal: PPAR research 20080101
Title: A phase II study of thalidomide in patients with brain metastases from malignant melanoma.
Journal: Acta oncologica (Stockholm, Sweden) 20080101
Title: Effects of palliative treatment with temozolomide in patients with high-grade gliomas.
Journal: Neurologia i neurochirurgia polska 20080101
Title: Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study.
Journal: BMC cancer 20080101
Title: Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
Journal: Journal of experimental therapeutics & oncology 20080101
Title: [Multivariate analysis of prognostic factors and survival in patients with 'glioblastoma multiforme'].
Journal: La Clinica terapeutica 20080101
Title: TMZ-BioShuttle--a reformulated temozolomide.
Journal: International journal of medical sciences 20080101
Title: Neuropsychological testing and biomarkers in the management of brain metastases.
Journal: Radiation oncology (London, England) 20080101
Title: Aggressive papillary glioneuronal tumor: case report and literature review.
Journal: Clinical neuropathology 20080101
Title: Concomitant radiochemotherapy in a patient with multiple sclerosis and glioblastoma.
Journal: Clinical neuropathology 20080101
Title: The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
Journal: Radiation oncology (London, England) 20080101
Title: Gliosarcomas in the elderly: analysis of 7 cases and clinico-pathological remarks.
Journal: Tumori 20080101
Title: Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines.
Journal: Journal of translational medicine 20080101
Title: Short-term effective treatment of CNS metastasis of sarcomatoid renal cell carcinoma with temozolomide and pegylated liposomal doxorubicin: A case report.
Journal: Cases journal 20080101
Title: Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age.
Journal: BMC medical genomics 20080101
Title: Case report on a patient with neurofibromatosis type 1 and a frontal cystic glioblastoma.
Journal: Neurologia i neurochirurgia polska 20080101
Title: Thalidomide influences growth and vasculogenic mimicry channel formation in melanoma.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: Radiotherapy-related tiredness in patients with glioblastoma multiforme (GBM).
Journal: Asian Pacific journal of cancer prevention : APJCP 20080101
Title: Discovery of DNA methylation markers in cervical cancer using relaxation ranking.
Journal: BMC medical genomics 20080101
Title: Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet.
Journal: Nutrition & metabolism 20080101
Title: The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivo.
Journal: Anticancer research 20080101
Title: Phase II Study of Temozolomide and Thalidomide in Patients with Unresectable or Metastatic Leiomyosarcoma.
Journal: Sarcoma 20080101
Title: A highly invasive human glioblastoma pre-clinical model for testing therapeutics.
Journal: Journal of translational medicine 20080101
Title: Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells.
Journal: Journal of translational medicine 20080101
Title: [(18)F]Fluoroethyltyrosine- positron emission tomography-guided radiotherapy for high-grade glioma.
Journal: Radiation oncology (London, England) 20080101
Title: Carboplatin and oral cyclophosphamide combination after temozolomide failure in malignant gliomas.
Journal: Tumori 20080101
Title: Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: Clinical Use of PPARgamma Ligands in Cancer.
Journal: PPAR research 20080101
Title: Aspergillus terreus brain abscess mimicking tumor progression in a patient with treated glioblastoma multiforme.
Journal: Clinical neuropathology 20080101
Title: MSH6 inactivation and emergent temozolomide resistance in human glioblastomas.
Journal: Clinical neurosurgery 20080101
Title: Reinduction of bevacizumab in combination with pegylated liposomal Doxorubicin in a patient with recurrent glioblastoma multiforme who progressed on bevacizumab/irinotecan.
Journal: Journal of oncology 20080101
Title: Disappearance of gadolinium enhancement in a chemoresistant astrocytoma of the tectum after high-dose interferon beta.
Journal: Tumori 20080101
Title: Stat3 expression and its correlation with proliferation and apoptosis/autophagy in gliomas.
Journal: Journal of oncology 20080101
Title: Delayed diagnosis of brain tumor in a patient with flexor spasms and spastic foot drop.
Journal: Annals of Indian Academy of Neurology 20080101
Title: Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry.
Journal: Drug design, development and therapy 20080101
Title: [Efficiency of radiation or chemoradiation therapy for diffusely growing brainstem tumors in children].
Journal: Vestnik rentgenologii i radiologii 20080101
Title: Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomas.
Journal: Molecular medicine reports 20080101
Title: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma-a critical review.
Journal: Clinical medicine. Oncology 20080101
Title: A Single Institution's Experience with Bevacizumab in Combination with Cytotoxic Chemotherapy in Progressive Malignant Glioma.
Journal: Clinical medicine. Oncology 20080101
Title: 2007 EORTC-NCI-ASCO annual meeting: molecular markers in cancer.
Journal: Ecancermedicalscience 20080101
Title: A phase II study of thalidomide and temozolomide in patients with brain metastases from malignant melanoma: lymphopenia correlates with response.
Journal: Ecancermedicalscience 20080101
Title: Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate.
Journal: Cancer letters 20071218
Title: Combining adenoviral oncolysis with temozolomide improves cell killing of melanoma cells.
Journal: International journal of cancer 20071215
Title: Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter.
Journal: Cancer research 20071215
Title: Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.
Journal: Cancer research 20071215
Title: Enhanced antitumour immunity by combined use of temozolomide and TAT-survivin pulsed dendritic cells in a murine glioma.
Journal: Immunology 20071201
Title: Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation.
Journal: Cancer investigation 20071201
Title: Editorial: what is new in the treatment of gliomas?
Journal: Current opinion in neurology 20071201
Title: Incorporating molecular tools into clinical trials and treatment for gliomas?
Journal: Current opinion in neurology 20071201
Title: Management of glioblastoma.
Journal: Expert opinion on pharmacotherapy 20071201
Title: Postoperative radiotherapy of glioblastoma multiforme: analysis and critical assessment of different treatment strategies and predictive factors.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20071201
Title: Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071201
Title: Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy.
Journal: Cancer investigation 20071201
Title: Acquired hypopigmentation (leukoderma) as a presenting feature of metastatic amelanotic melanoma with brain involvement.
Journal: Archives of neurology 20071201
Title: Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience.
Journal: British journal of neurosurgery 20071201
Title: Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide.
Journal: Japanese journal of clinical oncology 20071201
Title: Clinical course of high-grade glioma patients with a 'biopsy-only' surgical approach: a need for individualised treatment.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20071201
Title: Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomas.
Journal: The oncologist 20071201
Title: Management of patients with newly diagnosed malignant primary brain tumors with a focus on the evolving role of temozolomide.
Journal: Therapeutics and clinical risk management 20071201
Title: Topotecan: An evolving option in the treatment of relapsed small cell lung cancer.
Journal: Therapeutics and clinical risk management 20071201
Title: The RAS/mitogen activated protein (MAP) kinase pathway in melanoma biology and therapeutics.
Journal: Biologics : targets & therapy 20071201
Title: Cisplatin, gemcitabine, and treosulfan in relapsed stage IV cutaneous malignant melanoma patients.
Journal: British journal of cancer 20071119
Title: Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.
Journal: International journal of radiation oncology, biology, physics 20071115
Title: Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071115
Title: AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071115
Title: Temozolomide induces senescence but not apoptosis in human melanoma cells.
Journal: British journal of cancer 20071105
Title: O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
Journal: Cancer chemotherapy and pharmacology 20071101
Title: Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature.
Journal: Journal of neuro-oncology 20071101
Title: Temozolomide in pediatric low-grade glioma.
Journal: Pediatric blood & cancer 20071101
Title: Diffuse glioma growth: a guerilla war.
Journal: Acta neuropathologica 20071101
Title: Marked response to a cisplatin/docetaxel/temozolomide combination in a heavily pretreated patient with metastatic large cell neuroendocrine lung carcinoma.
Journal: Anti-cancer drugs 20071101
Title: Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly.
Journal: Journal of neuro-oncology 20071101
Title: Molecular targeted therapies and chemotherapy in malignant gliomas.
Journal: Current opinion in oncology 20071101
Title: Molecular genetic markers as predictors of response to chemotherapy in gliomas.
Journal: Current opinion in oncology 20071101
Title: Combined effect of 2-5A-linked antisense against telomerase RNA and conventional therapies on human malignant glioma cells in vitro and in vivo.
Journal: International journal of oncology 20071101
Title: Diagnosis and treatment of high-grade astrocytoma.
Journal: Neurologic clinics 20071101
Title: Phase I pharmacokinetic and pharmacodynamic study of temozolomide in pediatric patients with refractory or recurrent leukemia: a Children's Oncology Group Study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071101
Title: The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
Journal: Health technology assessment (Winchester, England) 20071101
Title: Adjuvant chemotherapy for adults with malignant glioma: a systematic review.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20071101
Title: Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
Journal: Neurosurgery 20071101
Title: Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme.
Journal: Clinical advances in hematology & oncology : H&O 20071101
Title: [The effect of oxygenation on the biological behaviour of tumours].
Journal: Orvosi hetilap 20071028
Title: Potential biochemical therapy of glioma cancer.
Journal: Biochemical and biophysical research communications 20071019
Title: The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Journal: Cancer research 20071015
Title: Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071015
Title: Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model.
Journal: Cancer chemotherapy and pharmacology 20071001
Title: Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model.
Journal: The Journal of investigative dermatology 20071001
Title: Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.
Journal: Journal of neuro-oncology 20071001
Title: Patients receiving standard-dose temozolomide therapy are at risk of Pneumocystis carinii pneumonia.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20071001
Title: MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas.
Journal: Laboratory investigation; a journal of technical methods and pathology 20071001
Title: Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
Journal: Cancer 20071001
Title: What approach will lead to cure of glioblastoma multiforme? In regard to Barani et al. (Int J Radiat Oncol Biol Phys 2007;68:324-333) and Jones and Sanghera (Int J Radiat Oncol Biol Phys 2007;68:441-448).
Journal: International journal of radiation oncology, biology, physics 20071001
Title: Triazene compounds: mechanism of action and related DNA repair systems.
Journal: Pharmacological research 20071001
Title: Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians.
Journal: International journal of clinical oncology 20071001
Title: O6-methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor induced resistance against temozolomide in human melanoma cells.
Journal: Molecular cancer therapeutics 20071001
Title: Gliadel wafers in the treatment of malignant glioma: a systematic review.
Journal: Current oncology (Toronto, Ont.) 20071001
Title: Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.
Journal: Therapeutics and clinical risk management 20071001
Title: Biochemotherapy of metastatic melanoma in patients with or without recently diagnosed brain metastases.
Journal: Cancer 20070915
Title: Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070915
Title: Use of molecular biomarkers for predicting the response to radiotherapy with or without chemotherapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070910
Title: Chemoradiotherapy in malignant glioma: standard of care and future directions.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070910
Title: Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.
Journal: Journal of neuro-oncology 20070901
Title: [What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?].
Journal: Presse medicale (Paris, France : 1983) 20070901
Title: Change in expression of MGMT during maturation of human monocytes into dendritic cells.
Journal: DNA repair 20070901
Title: Defining the standard of care for high-grade glioma--a NICE deal for UK patients?
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070901
Title: Impact of combination therapy with repeat surgery and temozolomide for recurrent or progressive glioblastoma multiforme: a prospective trial.
Journal: Surgical neurology 20070901
Title: [Role of MGMT and clinical applications in brain tumours].
Journal: Bulletin du cancer 20070901
Title: [A practical guide for the management of gliomas].
Journal: Bulletin du cancer 20070901
Title: Temozolomide treatment of an adult with a relapsing medulloblastoma.
Journal: Cancer investigation 20070901
Title: Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
Journal: Journal of neurosurgery 20070901
Title: Temozolomide for the treatment of metastatic melanoma: a systematic review.
Journal: The oncologist 20070901
Title: Chemotherapy and delivery in the treatment of primary brain tumors.
Journal: Current clinical pharmacology 20070901
Title: Diagnosis and management of primary intraocular lymphoma: an update.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20070901
Title: The neuro-steroid, 3beta androstene 17alpha diol exhibits potent cytotoxic effects on human malignant glioma and lymphoma cells through different programmed cell death pathways.
Journal: British journal of cancer 20070828
Title: Targeting HER proteins in cancer therapy and the role of the non-target HER3.
Journal: British journal of cancer 20070820
Title: Efficacy of temozolomide or dacarbazine in combination with an anthracycline for rescue chemotherapy in dogs with lymphoma.
Journal: Journal of the American Veterinary Medical Association 20070815
Title: The fallacy of single-agent chemotherapy for cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070810
Title: The prognostic value of health-related quality-of-life data in predicting survival in glioblastoma cancer patients: results from an international randomised phase III EORTC Brain Tumour and Radiation Oncology Groups, and NCIC Clinical Trials Group study.
Journal: British journal of cancer 20070806
Title: Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol?
Journal: Journal of neuro-oncology 20070801
Title: Chemical radiosensitizers for use in radiotherapy.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070801
Title: O6-methylguanine-DNA-methyltransferase (MGMT) gene therapy targeting haematopoietic stem cells: studies addressing safety issues.
Journal: DNA repair 20070801
Title: Novel role of triazenes in haematological malignancies: pilot study of Temozolomide, Lomeguatrib and IL-2 in the chemo-immunotherapy of acute leukaemia.
Journal: DNA repair 20070801
Title: Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.
Journal: Cancer gene therapy 20070801
Title: Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070801
Title: The economics of temozolomide in brain cancer.
Journal: Expert opinion on pharmacotherapy 20070801
Title: The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity.
Journal: Molecular cancer therapeutics 20070801
Title: Continuous hyperthermic peritoneal perfusion for desmoplastic small round cell tumor.
Journal: Journal of pediatric surgery 20070801
Title: Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas.
Journal: Neurologia medico-chirurgica 20070801
Title: Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070715
Title: Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Journal: Cancer research 20070715
Title: Prophylactic radiotherapy for glioblastoma in the elderly.
Journal: The New England journal of medicine 20070712
Title: Salvage therapy for primary central nervous system lymphoma with (90)Y-Ibritumomab and Temozolomide.
Journal: Journal of neuro-oncology 20070701
Title: Pulsed reduced dose-rate radiotherapy: case report : a novel re-treatment strategy in the management of recurrent glioblastoma multiforme.
Journal: Journal of neuro-oncology 20070701
Title: Melanoma of the anus disguised as hemorrhoids: surgical management illustrated by a case report.
Journal: Digestive diseases and sciences 20070701
Title: Survey of treatment recommendations for anaplastic oligodendroglioma.
Journal: Neuro-oncology 20070701
Title: Anaplastic astrocytoma in adults.
Journal: Critical reviews in oncology/hematology 20070701
Title: Comparison of herpes simplex virus- and conditionally replicative adenovirus-based vectors for glioblastoma treatment.
Journal: Cancer gene therapy 20070701
Title: In vitro responsiveness of glioma cell lines to multimodality treatment with radiotherapy, temozolomide, and epidermal growth factor receptor inhibition with cetuximab.
Journal: International journal of radiation oncology, biology, physics 20070701
Title: Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
Journal: Journal of neuro-oncology 20070701
Title: Radiochemotherapy for brain metastasis: how to define a role for temozolomide.
Journal: Onkologie 20070701
Title: Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors.
Journal: Onkologie 20070701
Title: Lessons learned in the development of targeted therapy for malignant gliomas.
Journal: Molecular cancer therapeutics 20070701
Title: Primary central nervous system lymphoma treated with rituximab plus temozolomide in a second line schedule.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20070701
Title: Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer.
Journal: The oncologist 20070701
Title: New chemotherapy options for the treatment of malignant gliomas.
Journal: Anti-cancer drugs 20070701
Title: Randomized trial of the combination of lomeguatrib and temozolomide compared with temozolomide alone in chemotherapy naive patients with metastatic cutaneous melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620
Title: Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.
Journal: Physics in medicine and biology 20070607
Title: Estimation of radiobiologic parameters and equivalent radiation dose of cytotoxic chemotherapy in malignant glioma.
Journal: International journal of radiation oncology, biology, physics 20070601
Title: Temozolomide-associated organizing pneumonitis.
Journal: Mayo Clinic proceedings 20070601
Title: Contributing factors of temozolomide resistance in MCF-7 tumor xenograft models.
Journal: Cancer biology & therapy 20070601
Title: A phase I study of thalidomide, capecitabine and temozolomide in advanced cancer.
Journal: Cancer biology & therapy 20070601
Title: Canadian recommendations for the treatment of glioblastoma multiforme.
Journal: Current oncology (Toronto, Ont.) 20070601
Title: Selective lymphopenia and opportunistic infections in neuroendocrine tumor patients receiving temozolomide.
Journal: Cancer investigation 20070601
Title: Microemulsions as topical delivery vehicles for the anti-melanoma prodrug, temozolomide hexyl ester (TMZA-HE).
Journal: The Journal of pharmacy and pharmacology 20070601
Title: Chemotherapy and role of the proliferation marker Ki-67 in digestive neuroendocrine tumors.
Journal: Endocrine-related cancer 20070601
Title: Hemorrhagic cystitis in a patient receiving conventional doses of dacarbazine for metastatic malignant melanoma: case report and review of the literature.
Journal: Clinical therapeutics 20070601
Title: Metastatic medulloblastoma in an adult; treatment with temozolomide.
Journal: Acta neurologica Belgica 20070601
Title: Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors.
Journal: Therapeutics and clinical risk management 20070601
Title: Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome.
Journal: Neurology 20070522
Title: Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070515
Title: Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070515
Title: Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas.
Journal: Journal of neuro-oncology 20070501
Title: Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.
Journal: Carcinogenesis 20070501
Title: Malignant transformation of conus medullaris ganglioglioma: case report.
Journal: Journal of neuro-oncology 20070501
Title: The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
Journal: Journal of molecular medicine (Berlin, Germany) 20070501
Title: A small proportion of glioblastoma patients are probably eligible for concomitant/adjuvant temozolomide.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070501
Title: Dynamic history of low-grade gliomas before and after temozolomide treatment.
Journal: Annals of neurology 20070501
Title: Successful treatment of leptomeningeal disease in colorectal cancer with a regimen of bevacizumab, temozolomide, and irinotecan.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070501
Title: ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070501
Title: Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Journal: Cancer research 20070501
Title: Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents.
Journal: Molecular cancer therapeutics 20070501
Title: Extracranial relapse of an anaplastic oligodendroglioma in an adolescent: case report and review of the literature.
Journal: Journal of pediatric hematology/oncology 20070501
Title: [Chemotherapy for malignant gliomas].
Journal: No shinkei geka. Neurological surgery 20070501
Title: Adjuvant therapy in glioblastomas: false steps and real advances.
Journal: Expert review of anticancer therapy 20070501
Title: Complete response to temozolomide treatment in an elderly patient with recurrent primary central nervous system lymphoma--case report.
Journal: Neurologia medico-chirurgica 20070501
Title: 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Journal: Neoplasia (New York, N.Y.) 20070501
Title: Expression of O6-methylguanine-deoxyribose nucleic acid methyltransferase and temozolomide response in a patient with a malignant spinal cord astrocytoma. Case report.
Journal: Journal of neurosurgery. Spine 20070501
Title: Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.
Journal: Annals of the Academy of Medicine, Singapore 20070501
Title: Salvage chemotherapy in progressive high-grade astrocytoma.
Journal: Annals of the Academy of Medicine, Singapore 20070501
Title: Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model.
Journal: Vaccine 20070430
Title: Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism.
Journal: British journal of cancer 20070423
Title: Methylguanine methyltransferase testing in glioblastoma: when and how?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070420
Title: Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070420
Title: Does high-dose carmustine increase overall survival in supratentorial high-grade malignant glioma? An EBMT retrospective study.
Journal: International journal of cancer 20070415
Title: Fatal reactivation of hepatitis B with temozolomide.
Journal: The New England journal of medicine 20070412
Title: Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57.
Journal: British journal of cancer 20070410
Title: Taming a mutinous mutant: an errant receptor becomes a prime cancer target.
Journal: Journal of the National Cancer Institute 20070404
Title: MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
Journal: Pediatric blood & cancer 20070401
Title: A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma.
Journal: Journal of neuro-oncology 20070401
Title: Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency.
Journal: DNA repair 20070401
Title: A phase II study of temozolomide therapy for poor-risk patients aged >or=60 years with acute myeloid leukemia: low levels of MGMT predict for response.
Journal: Leukemia 20070401
Title: Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens.
Journal: The Journal of pharmacology and experimental therapeutics 20070401
Title: The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation.
Journal: Oncology reports 20070401
Title: Temozolomide in children with progressive low-grade glioma.
Journal: Neuro-oncology 20070401
Title: [Glioma therapy up-date].
Journal: Neurologia (Barcelona, Spain) 20070401
Title: Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070401
Title: MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival.
Journal: Molecular cancer therapeutics 20070401
Title: Enhanced proapoptotic effects of tumor necrosis factor-related apoptosis-inducing ligand on temozolomide-resistant glioma cells.
Journal: Journal of neurosurgery 20070401
Title: Temozolomide as salvage treatment in primary brain lymphomas.
Journal: British journal of cancer 20070326
Title: Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.
Journal: British journal of cancer 20070326
Title: Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.
Journal: Neurology 20070320
Title: Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma.
Journal: Journal of neuro-oncology 20070301
Title: DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells.
Journal: Cell death and differentiation 20070301
Title: Local recurrence and distant metastasis of supratentorial primitive neuro-ectodermal tumor in an adult patient successfully treated with intensive induction chemotherapy and maintenance temozolomide.
Journal: Journal of neuro-oncology 20070301
Title: Local intracerebral administration of O(6)-benzylguanine combined with systemic chemotherapy with temozolomide of a patient suffering from a recurrent glioblastoma.
Journal: Journal of neuro-oncology 20070301
Title: Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours.
Journal: Apoptosis : an international journal on programmed cell death 20070301
Title: Current topics in melanoma.
Journal: Current opinion in oncology 20070301
Title: Prognosis factors of survival time in patients with glioblastoma multiforme: a multivariate analysis of 340 patients.
Journal: Acta neurochirurgica 20070301
Title: Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070301
Title: Fatal outcome related to carmustine implants in glioblastoma multiforme.
Journal: Acta neurochirurgica 20070301
Title: Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.
Journal: Molecular cancer therapeutics 20070301
Title: Motexafin gadolinium injection for the treatment of brain metastases in patients with non-small cell lung cancer.
Journal: International journal of nanomedicine 20070301
Title: Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma.
Journal: Neurology 20070227
Title: A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells.
Journal: British journal of cancer 20070226
Title: Interleukin-6 gene amplification and shortened survival in glioblastoma patients.
Journal: British journal of cancer 20070212
Title: Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma.
Journal: Pediatric blood & cancer 20070201
Title: Phase II study with the combination of gemcitabine and DTIC in patients with advanced soft tissue sarcomas.
Journal: Cancer chemotherapy and pharmacology 20070201
Title: Temozolomide/PLGA microparticles and antitumor activity against glioma C6 cancer cells in vitro.
Journal: International journal of pharmaceutics 20070201
Title: Administration of temozolomide during and after radiotherapy for newly diagnosed high-grade gliomas excluding glioblastoma multiforme.
Journal: Journal of neuro-oncology 20070201
Title: A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
Journal: Journal of neuro-oncology 20070201
Title: Ganglioglioma occurring with glioblastoma multiforme: separate lesions or the same lesion?
Journal: Clinical neurology and neurosurgery 20070201
Title: Combined effect of temozolomide and hyperthermia on human melanoma cell growth and O6-methylguanine-DNA methyltransferase activity.
Journal: International journal of oncology 20070201
Title: Motexafin gadolinium in the treatment of brain metastases.
Journal: Expert opinion on pharmacotherapy 20070201
Title: American Society of Hematology--48th Annual Meeting and Exposition. Therapeutic approaches for hematological cancers. 9-12 December 2006 Orlando, FL, USA.
Journal: IDrugs : the investigational drugs journal 20070201
Title: [Molecular pharmacology on DNA methylating agent temozolomide].
Journal: No shinkei geka. Neurological surgery 20070201
Title: Single-agent interleukin-2 in the treatment of metastatic melanoma.
Journal: Current oncology (Toronto, Ont.) 20070201
Title: Temozolomide for the treatment of metastatic melanoma.
Journal: Current oncology (Toronto, Ont.) 20070201
Title: [Temozolomide, an oral chemotherapeutic agent with potential severe toxicity].
Journal: Nederlands tijdschrift voor geneeskunde 20070127
Title: HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.
Journal: Current biology : CB 20070123
Title: A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.
Journal: British journal of cancer 20070115
Title: Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation?
Journal: Cancer 20070115
Title: O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.
Journal: Cancer research 20070115
Title: Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Journal: Oncogene 20070111
Title: Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: Morphological findings.
Journal: Human pathology 20070101
Title: Non-sufficient cell cycle control as possible clue for the resistance of human malignant glioma cells to clinically relevant treatment conditions.
Journal: Amino acids 20070101
Title: The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
Journal: Neuro-oncology 20070101
Title: Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070101
Title: Therapeutic advances for glioblastoma multiforme: current status and future prospects.
Journal: Current oncology reports 20070101
Title: Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070101
Title: New [1,2,4]triazolo[4,3-c]quinazoline enhances cisplatin- and temozolomide-induced growth inhibition and apoptosis in HL-60 cells.
Journal: Neoplasma 20070101
Title: Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents.
Journal: Cancer research 20070101
Title: Genetic aberrations in gliomatosis cerebri.
Journal: Neurosurgery 20070101
Title: Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life.
Journal: BMC cancer 20070101
Title: Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists.
Journal: Pituitary 20070101
Title: MGMT methylation status: the advent of stratified therapy in glioblastoma?
Journal: Disease markers 20070101
Title: Therapeutic advances in the treatment of brain metastases.
Journal: Clinical advances in hematology & oncology : H&O 20070101
Title: Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications.
Journal: Molecular cancer 20070101
Title: Efficacy of different regimens of adjuvant radiochemotherapy for treatment of glioblastoma.
Journal: Tumori 20070101
Title: A phase I study of cisplatin, temozolomide and thalidomide in patients with malignant brain tumors.
Journal: Anticancer research 20070101
Title: Temozolomide and thalidomide in the treatment of glioblastoma multiforme.
Journal: Anticancer research 20070101
Title: Successful treatment of palmar-plantar erythrodysesthesia possibly due to temozolomide with dexamethasone.
Journal: Journal of postgraduate medicine 20070101
Title: O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies.
Journal: Molecular cancer 20070101
Title: Impact of phase II trials with progression-free survival as end-points on survival-based phase III studies in patients with anaplastic gliomas.
Journal: BMC cancer 20070101
Title: Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors.
Journal: PloS one 20070101
Title: Pulmonary atypical carcinoid tumor with metastatic involvement of the pituitary gland causing functional hypopituitarism.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101
Title: Delirium likely caused by interaction between phenytoin and temozolomide.
Journal: Psychosomatics 20070101
Title: Standard fractionation intensity modulated radiation therapy (IMRT) of primary and recurrent glioblastoma multiforme.
Journal: Radiation oncology (London, England) 20070101
Title: Prognostic implication of clinical and pathologic features in patients with glioblastoma multiforme treated with concomitant radiation plus temozolomide.
Journal: Tumori 20070101
Title: Epidermal growth factor receptor serum levels and prognostic value in malignant gliomas.
Journal: Tumori 20070101
Title: Medical treatment and other combination regimens.
Journal: Tumori 20070101
Title: Medical treatment of uveal melanoma.
Journal: Tumori 20070101
Title: Effectiveness of interferon-beta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma.
Journal: World journal of surgical oncology 20070101
Title: Combination therapy with thalidomide, temozolomide and tamoxifen improves quality of life in patients with malignant astrocytomas.
Journal: Anticancer research 20070101
Title: Analysis of long-term survivors of glioblastoma multiforme in a single institution with aggressive local retreatment protocol.
Journal: Anticancer research 20070101
Title: Clinical impact of adjuvant chemotherapy in glioblastoma multiforme : a meta-analysis.
Journal: CNS drugs 20070101
Title: Radiotherapeutic alternatives for previously irradiated recurrent gliomas.
Journal: BMC cancer 20070101
Title: Oblimersen: Augmerosen, BCL-2 antisense oligonucleotide - Genta, G 3139, GC 3139, oblimersen sodium.
Journal: Drugs in R&D 20070101
Title: Metronomic chemotherapy dosing-schedules with estramustine and temozolomide act synergistically with anti-VEGFR-2 antibody to cause inhibition of human umbilical venous endothelial cell growth.
Journal: Acta oncologica (Stockholm, Sweden) 20070101
Title: Experimental iodine-125 seed irradiation of intracerebral brain tumors in nude mice.
Journal: Radiation oncology (London, England) 20070101
Title: Mechanisms operative in the antitumor activity of temozolomide in glioblastoma multiforme.
Journal: Cancer journal (Sudbury, Mass.) 20070101
Title: Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study.
Journal: Arthritis research & therapy 20070101
Title: The attitudes of brain cancer patients and their caregivers towards death and dying: a qualitative study.
Journal: BMC palliative care 20070101
Title: Chemoradiotherapy in high-grade gliomas.
Journal: Tumori 20070101
Title: Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas.
Journal: Journal of translational medicine 20070101
Title: Spontaneous immune responses against glioma-associated antigens in a long term survivor with malignant glioma.
Journal: Journal of translational medicine 20070101
Title: A rare case of malignant glioma suspected to have arisen from a cavernous sinus.
Journal: Brain tumor pathology 20070101
Title: Phase I dose escalation study of vinorelbine and topotecan combination chemotherapy in patients with recurrent lung cancer.
Journal: BMC cancer 20070101
Title: Pegylated liposomal doxorubicin in recurrent malignant glioma: analysis of a case series.
Journal: Oncology 20070101
Title: Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
Journal: Oncology 20070101
Title: [Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
Journal: Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101
Title: [Analysis of selected undesirable effects of cytostatic drugs in treatment of the central nervous system tumours in children. Preliminary report].
Journal: Medycyna wieku rozwojowego 20070101
Title: Targeted brain tumor treatment-current perspectives.
Journal: Drug target insights 20070101
Title: Therapeutic options for recurrent high-grade glioma in adult patients: recent advances.
Journal: Critical reviews in oncology/hematology 20061201
Title: Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20061201
Title: Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
Journal: European journal of cancer (Oxford, England : 1990) 20061201
Title: Glioblastoma in the elderly: current and future trends.
Journal: Critical reviews in oncology/hematology 20061201
Title: Potentiation of antiglioma effect with combined temozolomide and interferon-beta.
Journal: Oncology reports 20061201
Title: Chemotherapy and the treatment of brain metastases.
Journal: Hematology/oncology clinics of North America 20061201
Title: [Temozolomide in the treatment of recurrent malignant glioma].
Journal: No shinkei geka. Neurological surgery 20061201
Title: [Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20061201
Title: MGMT methylation: a marker of response to temozolomide in low-grade gliomas.
Journal: Annals of neurology 20061201
Title: [Recent advances in the medical treatment of glioma-temozolomide].
Journal: No to shinkei = Brain and nerve 20061201
Title: Focus on Fotemustine.
Journal: Journal of experimental & clinical cancer research : CR 20061201
Title: Gliosarcoma with infratemporal fossa extension. Case report.
Journal: Journal of neurosurgery 20061201
Title: Multiple gangliogliomas of the optic pathway.
Journal: British journal of neurosurgery 20061201
Title: New methods for direct delivery of chemotherapy for treating brain tumors.
Journal: The Yale journal of biology and medicine 20061201
Title: Skin delivery potency and antitumor activities of temozolomide ester prodrugs.
Journal: Cancer letters 20061128
Title: Genetic and metabolic predictors of chemosensitivity in oligodendroglial neoplasms.
Journal: British journal of cancer 20061120
Title: Phase II study of temozolomide in relapsed or refractory high-risk neuroblastoma: a joint Société Française des Cancers de l'Enfant and United Kingdom Children Cancer Study Group-New Agents Group Study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061120
Title: Irinotecan plus temozolomide for relapsed or refractory neuroblastoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061120
Title: [Gliomas in adults: primary non-surgical treatment].
Journal: Ugeskrift for laeger 20061120
Title: Chemotherapy for primary central nervous system lymphoma.
Journal: Neurosurgical focus 20061115
Title: Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
Journal: British journal of cancer 20061106
Title: A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas.
Journal: British journal of cancer 20061106
Title: Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo.
Journal: Computers in biology and medicine 20061101
Title: Radical surgery after chemotherapy: a new therapeutic strategy to envision in grade II glioma.
Journal: Journal of neuro-oncology 20061101
Title: In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo.
Journal: Journal of hepatology 20061101
Title: A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma.
Journal: Oncology reports 20061101
Title: Should concomitant and adjuvant treatment with temozolomide be used as standard therapy in patients with anaplastic glioma?
Journal: Critical reviews in oncology/hematology 20061101
Title: Chemotherapeutic options for primary brain tumors.
Journal: Current treatment options in oncology 20061101
Title: Predictive and prognostic markers in human glioblastomas.
Journal: Current treatment options in oncology 20061101
Title: The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
Journal: Molecular cancer therapeutics 20061101
Title: Glioma therapy in adults.
Journal: The neurologist 20061101
Title: Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.
Journal: Expert review of anticancer therapy 20061101
Title: [Cerebral tumours in the adult. A real increase].
Journal: La Revue du praticien 20061031
Title: [Pattern of care of high-grade gliomas].
Journal: La Revue du praticien 20061031
Title: Human melanoma cells expressing V600E B-RAF are susceptible to IGF1R targeting by small interfering RNAs.
Journal: Oncogene 20061026
Title: Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102).
Journal: Cancer 20061015
Title: Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061010
Title: Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
Journal: British journal of cancer 20061009
Title: Fatty acid synthase: a novel target for antiglioma therapy.
Journal: British journal of cancer 20061009
Title: Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
Journal: Journal of neuro-oncology 20061001
Title: Complications of a temozolomide overdose: a case report.
Journal: Journal of neuro-oncology 20061001
Title: Radiotherapy plus concomitant and adjuvant temozolomide for leptomeningeal pilomyxoid astrocytoma: a case study.
Journal: Journal of neuro-oncology 20061001
Title: Adding concomitant and adjuvant temozolomide to radiotherapy does not reduce health-related quality of life in people with glioblastoma.
Journal: Cancer treatment reviews 20061001
Title: Early change in glucose metabolic rate measured using FDG-PET in patients with high-grade glioma predicts response to temozolomide but not temozolomide plus radiotherapy.
Journal: International journal of radiation oncology, biology, physics 20061001
Title: 1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
Journal: European journal of cancer (Oxford, England : 1990) 20061001
Title: Cerebral blood volume, genotype and chemosensitivity in oligodendroglial tumours.
Journal: Neuroradiology 20061001
Title: A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
Journal: International journal of oncology 20061001
Title: Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm.
Journal: Clinical endocrinology 20061001
Title: Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20061001
Title: Long-term response of pituitary carcinoma to temozolomide. Report of two cases.
Journal: Journal of neurosurgery 20061001
Title: Spanish co-operative group of Medical Neuro-oncology (GENOM).
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001
Title: Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060920
Title: Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma.
Journal: Cancer 20060915
Title: A phase II study of extended dose temozolomide and thalidomide in previously treated patients with metastatic melanoma.
Journal: Journal of cancer research and clinical oncology 20060901
Title: Phase II trial of temozolomide and cisplatin followed by whole brain radiotherapy in non-small-cell lung cancer patients with brain metastases: a GLOT-GFPC study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060901
Title: Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
Journal: Brain : a journal of neurology 20060901
Title: Temozolomide treatment for newly diagnosed anaplastic oligodendrogliomas: a clinical efficacy trial.
Journal: Journal of neuro-oncology 20060901
Title: Safety and pharmacokinetics of temozolomide using a dose-escalation, metronomic schedule in recurrent paediatric brain tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20060901
Title: Radiotherapy and sequential temozolomide compared with radiotherapy with concomitant and sequential temozolomide in the treatment of newly diagnosed glioblastoma multiforme.
Journal: Anti-cancer drugs 20060901
Title: [Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060901
Title: Genetic alterations associated with acquired temozolomide resistance in SNB-19, a human glioma cell line.
Journal: Molecular cancer therapeutics 20060901
Title: Angiogenesis in cancer.
Journal: Vascular health and risk management 20060901
Title: Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901
Title: Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential.
Journal: International journal of nanomedicine 20060901
Title: Current status of clinical trials for glioblastoma.
Journal: Reviews on recent clinical trials 20060901
Title: Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide.
Journal: Cancer letters 20060808
Title: Is protracted low-dose temozolomide feasible in glioma patients?
Journal: Neurology 20060808
Title: Pro-invasive gene regulating effect of irradiation and combined temozolomide-radiation treatment on surviving human malignant glioma cells.
Journal: European journal of pharmacology 20060807
Title: Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy.
Journal: Current opinion in pharmacology 20060801
Title: Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801
Title: Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma.
Journal: Melanoma research 20060801
Title: Phase II multicentre study of temozolomide in combination with interferon alpha-2b in metastatic malignant melanoma.
Journal: Melanoma research 20060801
Title: MR-guided laser-induced interstitial thermotherapy of recurrent glioblastoma multiforme: preliminary results in 16 patients.
Journal: European journal of radiology 20060801
Title: Temozolomide chemotherapy in patients with recurrent malignant gliomas.
Journal: Journal of Korean medical science 20060801
Title: Metastatic spinal cord compression: the hidden danger.
Journal: Nature clinical practice. Oncology 20060801
Title: In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress.
Journal: Molecular cancer research : MCR 20060801
Title: A spatiotemporal, patient individualized simulation model of solid tumor response to chemotherapy in vivo: the paradigm of glioblastoma multiforme treated by temozolomide.
Journal: IEEE transactions on bio-medical engineering 20060801
Title: Temozolomide: a milestone in neuro-oncology and beyond?
Journal: Expert review of anticancer therapy 20060801
Title: Cerebral metastases--a therapeutic update.
Journal: Nature clinical practice. Neurology 20060801
Title: A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
Journal: British journal of cancer 20060717
Title: Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177.
Journal: International journal of radiation oncology, biology, physics 20060715
Title: Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas.
Journal: Pediatric blood & cancer 20060701
Title: Temozolomide in resistant or relapsed pediatric solid tumors.
Journal: Pediatric blood & cancer 20060701
Title: Role of temozolomide in pediatric brain tumors.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20060701
Title: Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
Journal: Journal of neuro-oncology 20060701
Title: Survival following adjuvant PCV or temozolomide for anaplastic astrocytoma.
Journal: Neuro-oncology 20060701
Title: Treatment-related myelodysplasia/AML in a patient with a history of breast cancer and an oligodendroglioma treated with temozolomide: case study and review of the literature.
Journal: Neuro-oncology 20060701
Title: Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas.
Journal: Oncology reports 20060701
Title: Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature.
Journal: Surgical neurology 20060701
Title: [Glioma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060701
Title: Combined biodifferentiating and antiangiogenic oral metronomic therapy is feasible and effective in relapsed solid tumors in children: single-center pilot study.
Journal: Onkologie 20060701
Title: Overall and progression-free survival in metastatic melanoma: analysis of a single-institution database.
Journal: Cancer control : journal of the Moffitt Cancer Center 20060701
Title: Temozolomide treatment of refractory epilepsy in a patient with an oligodendroglioma.
Journal: Epilepsia 20060701
Title: The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice.
Journal: Molecular cancer therapeutics 20060701
Title: Novel therapeutic approaches in pediatric and young adult sarcomas.
Journal: Current oncology reports 20060701
Title: Protein expression in experimental malignant glioma varies over time and is altered by radiotherapy treatment.
Journal: British journal of cancer 20060619
Title: Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060601
Title: Phase II study of temozolomide plus pegylated interferon-alpha-2b for metastatic melanoma.
Journal: Cancer 20060601
Title: Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
Journal: Cancer treatment reviews 20060601
Title: Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601
Title: Temozolomide: a novel treatment for pituitary carcinoma.
Journal: The Lancet. Oncology 20060601
Title: Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.
Journal: Nature clinical practice. Oncology 20060601
Title: Gliomatosis cerebri treatment in 11 elderly patients.
Journal: Journal of experimental & clinical cancer research : CR 20060601
Title: Chemotherapy for malignant gliomas.
Journal: Wiener medizinische Wochenschrift (1946) 20060601
Title: Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia.
Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20060601
Title: Autophagy: is it cancer's friend or foe?
Journal: Science (New York, N.Y.) 20060526
Title: Surgery, radiotherapy and temozolomide in treating high-grade gliomas.
Journal: Frontiers in bioscience : a journal and virtual library 20060501
Title: Use of 11C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas.
Journal: European journal of nuclear medicine and molecular imaging 20060501
Title: Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model.
Journal: Oncology reports 20060501
Title: Cimetidine, an unexpected anti-tumor agent, and its potential for the treatment of glioblastoma (review).
Journal: International journal of oncology 20060501
Title: Is current therapy of malignant gliomas beneficial for patients? Proteomics evidence of shifts in glioma cells expression patterns under clinically relevant treatment conditions.
Journal: Proteomics 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells.
Journal: PLoS medicine 20060501
Title: Pontine atypical neurocytoma: case report.
Journal: Neurosurgery 20060501
Title: Aplastic anaemia in patient with glioblastoma multiforme treated with temozolomide.
Journal: The Lancet. Oncology 20060501
Title: Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275.
Journal: Molecular cancer therapeutics 20060501
Title: The role of chemotherapy in the treatment of malignant astrocytomas.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20060501
Title: Present and potential future issues in glioblastoma treatment.
Journal: Expert review of anticancer therapy 20060501
Title: Cardiac metastasis from uterine leiomyosarcoma.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060501
Title: [Phototoxicity of dacarbazine (Deticene) not reinduced by temozolomide (Temodal)].
Journal: Annales de dermatologie et de venereologie 20060501
Title: Radiation therapy in the management of brain metastases from renal cell carcinoma.
Journal: Oncology (Williston Park, N.Y.) 20060501
Title: [Temozolomide--a new antitumor preparation in the treatment of central nervous system malignant tumors].
Journal: Georgian medical news 20060501
Title: Temozolomide for recurrent or progressive high-grade malignant glioma: results of an Austrian multicenter observational study.
Journal: Wiener klinische Wochenschrift 20060501
Title: The safety of the temozolomide in patients with malignant glioma.
Journal: Current drug safety 20060501
Title: Epigenetics as a mechanism driving polygenic clinical drug resistance.
Journal: British journal of cancer 20060424
Title: Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression.
Journal: Cancer 20060415
Title: A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
Journal: Cancer research 20060415
Title: Treatment options for glioblastoma.
Journal: Neurosurgical focus 20060415
Title: Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin.
Journal: Neurosurgical focus 20060415
Title: Management of malignant glioma: steady progress with multimodal approaches.
Journal: Neurosurgical focus 20060415
Title: New trends in the medical management of glioblastoma multiforme: the role of temozolomide chemotherapy.
Journal: Neurosurgical focus 20060415
Title: Autophagy, the Trojan horse to combat glioblastomas.
Journal: Neurosurgical focus 20060415
Title: Higher dosing of temozolomide? Regression of an anaplastic oligoastrocytoma over more than three years.
Journal: Journal of neuro-oncology 20060401
Title: O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro.
Journal: Pharmacological research 20060401
Title: Noninvasive 1H/13C magnetic resonance spectroscopic imaging of the intratumoral distribution of temozolomide.
Journal: Magnetic resonance in medicine 20060401
Title: Mutagenic potential of temozolomide in bone marrow cells in vivo.
Journal: Blood 20060401
Title: Altered expression of alpha-dystroglycan subunit in human gliomas.
Journal: Cancer biology & therapy 20060401
Title: Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060401
Title: Experimental designs for phase I and phase I/II dose-finding studies.
Journal: British journal of cancer 20060313
Title: Current strategies in treatment of oligodendroglioma: evolution of molecular signatures of response.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060310
Title: Recent advances in the treatment of malignant astrocytoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060310
Title: More from PHARMAC on temozolomide: feedback needed.
Journal: The New Zealand medical journal 20060310
Title: O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.
Journal: Toxicology and applied pharmacology 20060301
Title: Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial.
Journal: International journal of radiation oncology, biology, physics 20060301
Title: Phase II trial of temozolomide in children with recurrent high-grade glioma.
Journal: Journal of neuro-oncology 20060301
Title: Recent developments in the use of chemotherapy in brain tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20060301
Title: Lomeguatrib, a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase: phase I safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060301
Title: Oral regimen for metastatic neuroendocrine tumours.
Journal: The Lancet. Oncology 20060301
Title: Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine.
Journal: Molecular cancer therapeutics 20060301
Title: [Management of malignant gliomas diagnosed during pregnancy].
Journal: Revue neurologique 20060301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20060301
Title: Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060301
Title: Is protracted low-dose temozolomide feasible in glioma patients?
Journal: Neurology 20060214
Title: Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
Journal: Journal of neuro-oncology 20060201
Title: Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients.
Journal: Acta neurochirurgica 20060201
Title: A new approach to modeling covariate effects and individualization in population pharmacokinetics-pharmacodynamics.
Journal: Journal of pharmacokinetics and pharmacodynamics 20060201
Title: O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
Journal: Journal of neurochemistry 20060201
Title: Chemotherapy for glioblastoma multiforme (GBM).
Journal: Surgical neurology 20060201
Title: Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma.
Journal: Melanoma research 20060201
Title: A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study.
Journal: Melanoma research 20060201
Title: A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy.
Journal: American journal of clinical oncology 20060201
Title: Glioblastoma--more questions than answers?
Journal: Nature clinical practice. Oncology 20060201
Title: BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201
Title: Changing paradigms--an update on the multidisciplinary management of malignant glioma.
Journal: The oncologist 20060201
Title: Phase II study of temozolomide and thalidomide in patients with metastatic neuroendocrine tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060120
Title: Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma.
Journal: Cancer 20060115
Title: Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060110
Title: Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
Journal: Journal of the National Cancer Institute 20060104
Title: Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours.
Journal: Cancer chemotherapy and pharmacology 20060101
Title: The P140K mutant of human O(6)-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O(6)-(4-bromothenyl)guanine.
Journal: The journal of gene medicine 20060101
Title: Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases.
Journal: Journal of neuro-oncology 20060101
Title: Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma.
Journal: Frontiers in bioscience : a journal and virtual library 20060101
Title: Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma.
Journal: Cancer 20060101
Title: Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.
Journal: International journal of oncology 20060101
Title: Combination celecoxib and temozolomide in C6 rat glioma orthotopic model.
Journal: Oncology reports 20060101
Title: Phase II study of two-weekly temozolomide in patients with high-grade gliomas.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20060101
Title: Novel radiation-enhancing agents in malignant gliomas.
Journal: Seminars in radiation oncology 20060101
Title: Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060101
Title: Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation.
Journal: Nature clinical practice. Oncology 20060101
Title: Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells.
Journal: Molecular cancer therapeutics 20060101
Title: Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
Journal: Neuro-oncology 20060101
Title: A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668].
Journal: BMC cancer 20060101
Title: [Update on cerebral tumors].
Journal: Bulletin du cancer 20060101
Title: Advances in the treatment of primary brain tumors: dawn of a new era?
Journal: Current oncology reports 20060101
Title: The evolution of chemoradiation for glioblastoma: a modern success story.
Journal: Current oncology reports 20060101
Title: Primary malignant melanoma of the lung: a case report and review of the literature.
Journal: Clinical lung cancer 20060101
Title: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Journal: Molecular cancer 20060101
Title: Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol.
Journal: BMC cancer 20060101
Title: Treatments for astrocytic tumors in children: current and emerging strategies.
Journal: Paediatric drugs 20060101
Title: Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors.
Journal: Radiation oncology (London, England) 20060101
Title: High-grade gliomas: results in patients treated with adjuvant radiotherapy alone and with adjuvant radio-chemotherapy.
Journal: Anticancer research 20060101
Title: Primitive neuroectodermal tumor (PNET) of the brain diagnosed during pregnancy.
Journal: Anticancer research 20060101
Title: Primary and metastatic brain tumors.
Journal: Forum (Genoa, Italy) 20060101
Title: PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers?
Journal: International journal of medical sciences 20060101
Title: Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.
Journal: BMC complementary and alternative medicine 20060101
Title: In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model.
Journal: BMC cancer 20060101
Title: Temozolomide and radiotherapy as first-line treatment of high-grade gliomas.
Journal: Tumori 20060101
Title: Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26).
Journal: BMC cancer 20060101
Title: Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma.
Journal: Molecular cancer 20060101
Title: A comparative study on the cost of new antibiotics and drugs of other therapeutic categories.
Journal: PloS one 20060101
Title: [Results of radical removal of malignant cerebral gliomas, by using computer-assisted navigation, followed by adjuvant therapy].
Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko 20060101
Title: [Usefulness of the antisense and triplex anti-IGF-1 techniques for postoperative cellular gene therapy of malignant gliomas expressing IGF-1].
Journal: Neurologia i neurochirurgia polska 20060101
Title: A phase II clinical study on relapsed malignant gliomas treated with electro-hyperthermia.
Journal: In vivo (Athens, Greece) 20060101
Title: Post-operative combined radiation and chemotherapy with temozolomide and irinotecan in patients with high-grade astrocytic tumors. A phase II study with biomarker evaluation.
Journal: Anticancer research 20060101
Title: Extensive local and systemic therapy in extraneural metastasized glioblastoma multiforme.
Journal: Anticancer research 20060101
Title: Concomitant radiochemotherapy with temozolomide in non-selected patients with newly diagnosed high-grade gliomas.
Journal: Anticancer research 20060101
Title: Phase II Trial of Doxorubicin Plus Escalated High-Dose Ifosfamide in Patients With Advanced Soft Tissue Sarcomas of the Adult: A Study of the Spanish Group for Research on Sarcomas (GEIS).
Journal: Sarcoma 20060101
Title: [Chemotherapy registry quality in Andalusian hospital pharmacy departments].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101
Title: [Treatment results of children and adolescents with brain stem tumours. Own experiences].
Journal: Medycyna wieku rozwojowego 20060101
Title: Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
Journal: Clinical neurosurgery 20060101
Title: Brain metastasis--evidence based management.
Journal: Journal of cancer research and therapeutics 20060101
Title: Combined modality treatment of glioblastoma multiforme: the role of temozolomide.
Journal: Reviews on recent clinical trials 20060101
Title: Spotlight on cancer informatics.
Journal: Cancer informatics 20060101
Title: Applying a 4D multiscale in vivo tumor growth model to the exploration of radiotherapy scheduling: the effects of weekend treatment gaps and p53 gene status on the response of fast growing solid tumors.
Journal: Cancer informatics 20060101
Title: Predictive utility of circulating methylated DNA in serum of melanoma patients receiving biochemotherapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051220
Title: Evidence, economics, and emotions: the case for temozolomide.
Journal: The New Zealand medical journal 20051216
Title: PHARMAC's response on temozolomide and funding costly medicines that prolong life shortly.
Journal: The New Zealand medical journal 20051216
Title: Low-dose outpatient chemobiotherapy with temozolomide, granulocyte-macrophage colony stimulating factor, interferon-alpha2b, and recombinant interleukin-2 for the treatment of metastatic melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051210
Title: Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051210
Title: The treatment of high grade gliomas and diffuse intrinsic pontine tumors of childhood and adolescence: a historical - and futuristic - perspective.
Journal: Journal of neuro-oncology 20051201
Title: Salvage temozolomide for prior temozolomide responders.
Journal: Cancer 20051201
Title: Treatment of astrocytomas.
Journal: Current opinion in neurology 20051201
Title: Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
Journal: European journal of cancer (Oxford, England : 1990) 20051201
Title: Temozolomide in combination with cisplatin in patients with metastatic melanoma: a phase II trial.
Journal: Melanoma research 20051201
Title: Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
Journal: The Lancet. Oncology 20051201
Title: Temozolomide in the treatment of recurrent malignant glioma in Chinese patients.
Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20051201
Title: Hematopoietic stem cell transduction and amplification in large animal models.
Journal: Human gene therapy 20051201
Title: [Concomitant radiotherapy with chemotherapy in patients with glioblastoma].
Journal: Bulletin du cancer 20051201
Title: Extended continuous oral temozolomide in patients with progressive metastatic renal cell carcinoma not responding to interferon alpha 2b.
Journal: Journal of chemotherapy (Florence, Italy) 20051201
Title: Temozolomide: a milestone in the pharmacotherapy of brain tumors.
Journal: Future oncology (London, England) 20051201
Title: Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial.
Journal: Nature clinical practice. Neurology 20051201
Title: Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase.
Journal: Cancer research 20051115
Title: O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.
Journal: British journal of cancer 20051114
Title: Relapse of primary CNS lymphoma after more than 10 years in complete remission.
Journal: Journal of neurology 20051101
Title: Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study.
Journal: Lung cancer (Amsterdam, Netherlands) 20051101
Title: Postoperative radiotherapy and chemotherapy in the management of oligodendroglioma: single institutional review of 88 patients.
Journal: Journal of neuro-oncology 20051101
Title: A Phase I trial of protracted oral fixed-dose temozolomide.
Journal: Cancer 20051101
Title: Organ- and treatment-specific local response rates to systemic and local treatment modalities in stage IV melanoma.
Journal: The British journal of dermatology 20051101
Title: Current strategies in whole-brain radiation therapy for brain metastases.
Journal: Neurosurgery 20051101
Title: Chemotherapy in brain metastases.
Journal: Neurosurgery 20051101
Title: Current treatment paradigms for the management of patients with brain metastases.
Journal: Neurosurgery 20051101
Title: Adding temozolomide to radiotherapy prolongs survival in people with glioblastoma.
Journal: Cancer treatment reviews 20051101
Title: Avoiding glucocorticoid administration in a neurooncological case.
Journal: Cancer biology & therapy 20051101
Title: Emerging targeted treatments for malignant glioma.
Journal: Expert opinion on emerging drugs 20051101
Title: Systemic temozolomide combined with loco-regional mitoxantrone in treating recurrent glioblastoma.
Journal: Journal of neuro-oncology 20051101
Title: 10 questions about temozolomide and the treatment of brain tumors.
Journal: The neurologist 20051101
Title: A congenital brain tumor associated with assisted in vitro fertilization. Case report.
Journal: Journal of neurosurgery 20051101
Title: Phase I study of O6-benzylguanine and temozolomide administered daily for 5 days to pediatric patients with solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020
Title: A phase II trial of temozolomide as a 6-week, continuous, oral schedule in patients with advanced soft tissue sarcoma: a study by the Spanish Group for Research on Sarcomas.
Journal: Cancer 20051015
Title: Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051015
Title: [Standards and new developments in the chemotherapy of glioblastomas].
Journal: Deutsche medizinische Wochenschrift (1946) 20051007
Title: Secondary Ph+ acute lymphoblastic leukemia after temozolomide.
Journal: Annals of hematology 20051001
Title: Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
Journal: Cancer 20051001
Title: Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy.
Journal: International journal of radiation oncology, biology, physics 20051001
Title: Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051001
Title: A low rate of central nervous system progression in a phase II trial of outpatient chemobiologic therapy with cisplatin, temozolomide, interleukin-2, and interferon alfa 2-B for metastatic malignant melanoma.
Journal: American journal of clinical oncology 20051001
Title: Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051001
Title: Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment.
Journal: Neoplasia (New York, N.Y.) 20051001
Title: A retrospective study of biochemotherapy for metastatic melanoma: the importance of dose intensity.
Journal: Cancer biotherapy & radiopharmaceuticals 20051001
Title: Dose finding and O6-alkylguanine-DNA alkyltransferase study of cisplatin combined with temozolomide in paediatric solid malignancies.
Journal: British journal of cancer 20050905
Title: Recent advances in conventional-dose salvage chemotherapy in patients with cisplatin-resistant or refractory testicular germ cell tumors.
Journal: European urology 20050901
Title: [Radiotherapy for glioblastomas: from radiobiology to concomitant chemotherapy].
Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20050901
Title: IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide.
Journal: Cancer research 20050901
Title: Phase II trial of temozolomide in patients with pretreated cutaneous T-cell lymphoma.
Journal: Haematologica 20050901
Title: Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma.
Journal: Molecular cancer therapeutics 20050901
Title: Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
Journal: Molecular cancer therapeutics 20050901
Title: Inactivation of p53 sensitizes astrocytic glioma cells to BCNU and temozolomide, but not cisplatin.
Journal: Journal of neuro-oncology 20050901
Title: [Role of extracellular matrix degradation enzyme for glioma invasion].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Chemotherapy for gliomas in children].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Treatment of malignant gliomas in the elderly].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Chemotherapy for brain metastases].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: The role of chemotherapy in the treatment of low-grade glioma. A review of the literature.
Journal: Acta neurologica Belgica 20050901
Title: Efficiency, quality and bureaucracy: not always in the same bag!!
Journal: European journal of cancer (Oxford, England : 1990) 20050901
Title: Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
Journal: International journal of cancer 20050820
Title: Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
Journal: Cancer research 20050815
Title: Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
Journal: Oncogene 20050804
Title: Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs.
Journal: International journal of oncology 20050801
Title: Brain metastases in metastatic non-small cell lung cancer responding to single-agent gefitinib: a case report.
Journal: Anti-cancer drugs 20050801
Title: Cardiac metastasis of melanoma.
Journal: Melanoma research 20050801
Title: Osseous metastasis of pineoblastoma: a case report and review of the literature.
Journal: Journal of neuro-oncology 20050801
Title: Gliosarcomas: analysis of 11 cases do two subtypes exist?
Journal: Journal of neuro-oncology 20050801
Title: HER1/EGFR tyrosine kinase inhibitors for the treatment of glioblastoma multiforme.
Journal: Journal of neuro-oncology 20050801
Title: Author comments on drug-dispensing change.
Journal: Clinical journal of oncology nursing 20050801
Title: [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
Journal: Wiener medizinische Wochenschrift (1946) 20050801
Title: The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death.
Journal: Cancer research 20050715
Title: Low-grade primary meningeal lymphoma: case report and review of the literature.
Journal: Neurosurgical review 20050701
Title: Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050701
Title: Chemopotentiation by PARP inhibitors in cancer therapy.
Journal: Pharmacological research 20050701
Title: Clinical perspectives of PARP inhibitors.
Journal: Pharmacological research 20050701
Title: Temozolomide in uterine leiomyosarcomas.
Journal: Gynecologic oncology 20050701
Title: Artificial tumor model suitable for monitoring 31P and 13C NMR spectroscopic changes during chemotherapy-induced apoptosis in human glioma cells.
Journal: Magnetic resonance in medicine 20050701
Title: Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis.
Journal: Journal of neuro-oncology 20050701
Title: Radiotherapy plus adjuvant temozolomide for the treatment of glioblastoma--a paradigm shift.
Journal: Nature clinical practice. Oncology 20050701
Title: Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620
Title: How lymphotoxic is dose-intensified temozolomide? The glioblastoma experience.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620
Title: [Temozolomide in patients with a glioblastoma multiforme: new developments].
Journal: Nederlands tijdschrift voor geneeskunde 20050618
Title: [Favourable result for temozolomide in recurrent high-grade glioma].
Journal: Nederlands tijdschrift voor geneeskunde 20050618
Title: Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
Journal: Cancer 20050615
Title: Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.
Journal: Journal of the National Cancer Institute 20050615
Title: Treatment of brain tumors.
Journal: The New England journal of medicine 20050602
Title: Treatment of brain tumors.
Journal: The New England journal of medicine 20050602
Title: Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20050601
Title: Temozolomide and cisplatin versus temozolomide in patients with advanced melanoma: a randomized phase II study of the Hellenic Cooperative Oncology Group.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050601
Title: Engineering 3-alkyltriazenes to block bcr-abl kinase: a novel strategy for the therapy of advanced bcr-abl expressing leukemias.
Journal: Leukemia research 20050601
Title: Neoadjuvant phase II multicentre study of new agents in patients with malignant glioma after minimal surgery. Report of a cohort of 187 patients treated with temozolomide.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050601
Title: Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20050601
Title: Role of novel targeted therapies in the clinic.
Journal: British journal of cancer 20050601
Title: Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence.
Journal: Cancer research 20050601
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: Maintenance of fertility following treatment with temozolomide for a high grade astrocytoma.
Journal: Journal of neuro-oncology 20050601
Title: Modeling antitumor activity in xenograft tumor treatment.
Journal: Biometrical journal. Biometrische Zeitschrift 20050601
Title: Effects of cisplatin on olfactory function in cancer patients.
Journal: British journal of cancer 20050509
Title: Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.
Journal: Cancer chemotherapy and pharmacology 20050501
Title: Treatment of brain metastases from melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050501
Title: Concomitant chemoradiotherapy followed by adjuvant temozolomide improves survival in glioblastoma multiforme.
Journal: Current neurology and neuroscience reports 20050501
Title: Optimal role of temozolomide in the treatment of malignant gliomas.
Journal: Current neurology and neuroscience reports 20050501
Title: Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050501
Title: Treatment of metastatic malignant melanoma.
Journal: Current treatment options in oncology 20050501
Title: Local drug delivery in recurrent malignant gliomas.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501
Title: Temozolomide and radiation for aggressive pediatric central nervous system malignancies.
Journal: Journal of pediatric hematology/oncology 20050501
Title: P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy.
Journal: Journal of neuro-oncology 20050501
Title: Can a rational design for metronomic chemotherapy dosing be devised?
Journal: British journal of cancer 20050425
Title: Dexamethasone decreases temozolomide-induced apoptosis in human gliobastoma T98G cells.
Journal: Glia 20050415
Title: Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.
Journal: Cancer research 20050415
Title: Cerebrospinal fluid-disseminated meningioma.
Journal: Cancer 20050401
Title: Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050401
Title: O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050401
Title: A phase II study of concurrent temozolomide and cis-retinoic acid with radiation for adult patients with newly diagnosed supratentorial glioblastoma.
Journal: International journal of radiation oncology, biology, physics 20050401
Title: Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death.
Journal: Neuro-oncology 20050401
Title: Adjuvant chemotherapy in the treatment of high grade gliomas.
Journal: Cancer treatment reviews 20050401
Title: [Highly quality-controlled radiation therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050401
Title: Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
Journal: Journal of neurosurgery 20050401
Title: [New place of the chemotherapy in gliomas].
Journal: Bulletin du cancer 20050401
Title: Does addition of temozolomide to whole brain radiotherapy improve outcome in patients with brain metastases?
Journal: Nature clinical practice. Oncology 20050401
Title: Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations.
Journal: British journal of cancer 20050328
Title: PARP inhibitors for cancer therapy.
Journal: Expert reviews in molecular medicine 20050315
Title: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
Journal: The New England journal of medicine 20050310
Title: MGMT gene silencing and benefit from temozolomide in glioblastoma.
Journal: The New England journal of medicine 20050310
Title: Chemotherapy for brain tumors--a new beginning.
Journal: The New England journal of medicine 20050310
Title: Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
Journal: Neurology 20050308
Title: Temozolomide in the treatment of solid tumours: current results and rationale for dosing/scheduling.
Journal: Critical reviews in oncology/hematology 20050301
Title: Expression of ABC-1 transporter is elevated in human glioma cells under irradiation and temozolomide treatment.
Journal: Amino acids 20050301
Title: Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20050301
Title: Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy.
Journal: Blood 20050201
Title: Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors.
Journal: International journal of oncology 20050201
Title: Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.
Journal: European journal of cancer (Oxford, England : 1990) 20050201
Title: Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.
Journal: Journal of neuro-oncology 20050201
Title: Successful treatment of a chemoresistant tumor with temozolomide in an adult patient: report of a recurrent intracranial mesenchymal chondrosarcoma.
Journal: Journal of neuro-oncology 20050201
Title: [Gliomatosis cerebri].
Journal: Revue neurologique 20050201
Title: The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20050117
Title: Repeated-measures models with constrained parameters for incomplete data in tumour xenograft experiments.
Journal: Statistics in medicine 20050115
Title: Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
Journal: Journal of cancer research and clinical oncology 20050101
Title: Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98).
Journal: Cancer 20050101
Title: Neuro-oncology: the growing role of chemotherapy in glioma.
Journal: The Lancet. Neurology 20050101
Title: Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial.
Journal: International journal of radiation oncology, biology, physics 20050101
Title: Research news and notes.
Journal: Surgical neurology 20050101
Title: Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
Journal: Neuro-oncology 20050101
Title: Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study.
Journal: Journal of neuro-oncology 20050101
Title: Cerebral metastases of malignant melanoma: contemporary treatment modalities and survival outcome.
Journal: Neoplasma 20050101
Title: Clinical practice guideline on the optimal radiotherapeutic management of brain metastases.
Journal: BMC cancer 20050101
Title: Response to temozolomide in second-line treatment of recurrent nonsmall cell lung carcinoma: case report.
Journal: Cancer investigation 20050101
Title: Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
Journal: Cancer investigation 20050101
Title: Temozolomide and cisplatin in avdanced malignant melanoma.
Journal: Anticancer research 20050101
Title: Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma.
Journal: BMC cancer 20050101
Title: Phenytoin may increase the efficacy of temozolomide by methylating DNA-repair enzyme, O6-methylguanine-DNA methyltransferase in patients with glioblastoma.
Journal: Medical hypotheses 20050101
Title: Cancer cell adaptation to chemotherapy.
Journal: BMC cancer 20050101
Title: Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme.
Journal: PharmacoEconomics 20050101
Title: A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF.
Journal: Cancer investigation 20050101
Title: Disseminated primary diffuse leptomeningeal gliomatosis: a case report with liquid based and conventional smear cytology.
Journal: CytoJournal 20050101
Title: Targeting energy metabolism in brain cancer: review and hypothesis.
Journal: Nutrition & metabolism 20050101
Title: Epigenetics of cervical cancer. An overview and therapeutic perspectives.
Journal: Molecular cancer 20050101
Title: New drug extends lives of brain cancer patients.
Journal: FDA consumer 20050101
Title: Long-term disease-free survival in advanced melanomas treated with nitrosoureas: mechanisms and new perspectives.
Journal: BMC cancer 20050101
Title: Treatment of unresectable glioblastoma multiforme.
Journal: Anticancer research 20050101
Title: Glioblastoma multiforme treated by the chemotherapeutic agent temozolomide in vivo: a 4D simulation model of the tumor response.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101
Title: Synthesis and antitumor activity of methyltriazene prodrugs simultaneously releasing DNA-methylating agents and the antiresistance drug O(6)-benzylguanine.
Journal: Journal of medicinal chemistry 20041230
Title: Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly population.
Journal: Cancer 20041215
Title: Immunochemotherapy with rituximab and temozolomide for central nervous system lymphomas.
Journal: Cancer 20041215
Title: The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20041201
Title: Advances in the biology and treatment of oligodendrogliomas.
Journal: Current opinion in neurology 20041201
Title: The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells.
Journal: International journal of oncology 20041201
Title: Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041201
Title: Biochemotherapy in patients with advanced vulvovaginal mucosal melanoma.
Journal: Melanoma research 20041201
Title: Pharmacokinetic model-predicted anticancer drug concentrations in human tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
Title: Response of low-grade oligodendroglial tumors to temozolomide.
Journal: Journal of neuro-oncology 20041201
Title: Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM).
Journal: Journal of neuro-oncology 20041201
Title: Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas.
Journal: Ideggyogyaszati szemle 20041120
Title: Alkylation damage in DNA and RNA--repair mechanisms and medical significance.
Journal: DNA repair 20041102
Title: Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Recurrent spinal ependymoma showing partial remission under Imatimib.
Journal: Acta neurochirurgica 20041101
Title: Can we afford to add chemotherapy to radiotherapy for glioblastoma multiforme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death.
Journal: Cancer 20041101
Title: Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study.
Journal: British journal of cancer 20041101
Title: Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20041101
Title: Temozolomide is a novel regional infusion agent for the treatment of advanced extremity melanoma.
Journal: American journal of surgery 20041101
Title: Hierarchical models for tumor xenograft experiments in drug development.
Journal: Journal of biopharmaceutical statistics 20041101
Title: Making inferences about projected completors in longitudinal studies.
Journal: Journal of biopharmaceutical statistics 20041101
Title: Recent advances in primary CNS lymphoma.
Journal: Current opinion in oncology 20041101
Title: Innovative therapy for patients with brain metastases: oral treatments.
Journal: Journal of chemotherapy (Florence, Italy) 20041101
Title: How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial.
Journal: Neurology 20041012
Title: Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20041001
Title: The role of taxanes in the treatment of metastatic melanoma.
Journal: Melanoma research 20041001
Title: Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.
Journal: Cancer research 20041001
Title: Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase.
Journal: Molecular cancer therapeutics 20041001
Title: Diagnosis and management of oligodendroglioma.
Journal: Seminars in oncology 20041001
Title: Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium.
Journal: Journal of neuro-oncology 20041001
Title: Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
Journal: Journal of neuro-oncology 20041001
Title: Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas.
Journal: Journal of neuro-oncology 20041001
Title: New (1-deaza)purine derivatives via efficient C-2 nitration of the (1-deaza)purine ring.
Journal: Nucleosides, nucleotides & nucleic acids 20041001
Title: Management of metastatic cutaneous melanoma.
Journal: Oncology (Williston Park, N.Y.) 20041001
Title: Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
Journal: Cancer research 20040915
Title: Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
Journal: Neurology 20040914
Title: Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas.
Journal: Neurology 20040914
Title: Phase II trial of carboplatin and etoposide for patients with recurrent high-grade glioma.
Journal: British journal of cancer 20040913
Title: Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides.
Journal: British journal of cancer 20040913
Title: Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line.
Journal: British journal of cancer 20040913
Title: Treatment of advanced melanoma with temozolomide: I.
Journal: Current oncology reports 20040901
Title: Treatment of advanced melanoma with temozolomide: II.
Journal: Current oncology reports 20040901
Title: DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
Journal: Molecular pharmacology 20040901
Title: Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide.
Journal: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20040901
Title: Current therapies for glioblastoma.
Journal: Clinical advances in hematology & oncology : H&O 20040901
Title: A prognostic index that predicts outcome following palliative whole brain radiotherapy for patients with metastatic malignant melanoma.
Journal: British journal of cancer 20040831
Title: Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
Journal: Neurology 20040810
Title: Temozolomide in paediatric high-grade glioma: a key for combination therapy?
Journal: British journal of cancer 20040802
Title: Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040801
Title: CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040801
Title: Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Journal: Molecular cancer therapeutics 20040801
Title: The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma.
Journal: Melanoma research 20040801
Title: Temozolomide and interferon-alpha in metastatic melanoma: a phase II study of the Italian Melanoma Intergroup.
Journal: Melanoma research 20040801
Title: Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.
Journal: Human gene therapy 20040801
Title: Gliomatosis cerebri: better definition, better treatment.
Journal: Neurology 20040727
Title: Initial chemotherapy in gliomatosis cerebri.
Journal: Neurology 20040727
Title: Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide.
Journal: Neurology 20040727
Title: Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors.
Journal: International journal of radiation oncology, biology, physics 20040715
Title: Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma.
Journal: Cancer research 20040715
Title: Immunochemotherapy with rituximab and temozolomide for central nervous system lymphomas.
Journal: Cancer 20040701
Title: Distinct responses of xenografted gliomas to different alkylating agents are related to histology and genetic alterations.
Journal: Cancer research 20040701
Title: Immediate postoperative radiotherapy or 'watch and wait' in the management of adult low-grade glioma?
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20040701
Title: Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial.
Journal: European journal of cancer (Oxford, England : 1990) 20040701
Title: Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review.
Journal: European journal of cancer (Oxford, England : 1990) 20040701
Title: Temozolomide and interferon alpha 2b in metastatic melanoma stage IV.
Journal: The British journal of dermatology 20040701
Title: Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
Journal: Neuro-oncology 20040701
Title: One week on/one week off: a novel active regimen of temozolomide for recurrent glioblastoma.
Journal: Neurology 20040608
Title: Prolonged schedule of temozolomide (Temodal) plus liposomal doxorubicin (Caelyx) in advanced solid cancers.
Journal: Anti-cancer drugs 20040601
Title: Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040601
Title: Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040601
Title: In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.
Journal: Melanoma research 20040601
Title: A phase II evaluation of Temozolomide in patients with recurrent epithelial ovarian cancer.
Journal: Gynecologic oncology 20040601
Title: Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.
Journal: Journal of neurosurgery 20040601
Title: Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.
Journal: Current opinion in investigational drugs (London, England : 2000) 20040601
Title: Current and future trials of the EORTC brain tumor group.
Journal: Onkologie 20040601
Title: Evaluation of temozolomide in patients with myelodysplastic syndrome.
Journal: Leukemia & lymphoma 20040601
Title: Long-term outcome of oligodendrogliomas.
Journal: Neurology 20040525
Title: Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20040517
Title: Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations.
Journal: Cancer 20040515
Title: Modeling antitumor activity by using a non-linear mixed-effects model.
Journal: Mathematical biosciences 20040501
Title: BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20040501
Title: Dacarbazine but not temozolomide induces phototoxic dermatitis in patients with malignant melanoma.
Journal: Journal of the American Academy of Dermatology 20040501
Title: First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040501
Title: Irinotecan-induced interstitial pneumonia.
Journal: The Lancet. Oncology 20040501
Title: Ifosfamide/carboplatin/etoposide (ICE) as front-line, topotecan/cyclophosphamide as second-line and oral temozolomide as third-line treatment for advanced neuroblastoma over one year of age.
Journal: Acta paediatrica (Oslo, Norway : 1992). Supplement 20040501
Title: Transient local response and persistent tumor control in a child with recurrent malignant glioma: treatment with combination therapy including dendritic cell therapy. Case report.
Journal: Journal of neurosurgery 20040501
Title: Disposition and pharmacokinetics of temozolomide in rat.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501
Title: Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
Journal: Cancer 20040415
Title: Temozolomide for treatment-resistant recurrent meningioma.
Journal: Neurology 20040413
Title: Unusual and severe symptomatic impairment of neutrophil function after one cycle of temozolomide in patients with malignant glioma.
Journal: Annals of hematology 20040401
Title: Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells.
Journal: Cell death and differentiation 20040401
Title: Phase II trial of temozolomide in patients with cisplatin-refractory germ cell tumors.
Journal: Investigational new drugs 20040401
Title: Biochemotherapy in patients with metastatic anorectal mucosal melanoma.
Journal: Cancer 20040401
Title: Oligodendroglioma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors. Case report with histological and molecular differentiation of the tumors and review of the literature.
Journal: Journal of neurosurgery 20040401
Title: Survival and prognostic factors in patients with brain metastases from malignant melanoma.
Journal: Onkologie 20040401
Title: Complete response of multiple melanoma brain metastases after treatment with temozolomide.
Journal: Onkologie 20040401
Title: [Survival analysis following the addition of temozolomide to surgery and radiotherapy in patients with glioblastoma multiforme].
Journal: Neurocirugia (Asturias, Spain) 20040401
Title: [Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation].
Journal: Medicina clinica 20040327
Title: Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme.
Journal: Cancer 20040315
Title: Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040315
Title: Primary cultures of microglial cells for testing toxicity of anticancer drugs.
Journal: Toxicology letters 20040314
Title: Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.
Journal: British journal of pharmacology 20040301
Title: A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040301
Title: Management of brain metastases in patients with melanoma.
Journal: Current opinion in oncology 20040301
Title: Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy.
Journal: British journal of cancer 20040223
Title: Selective CD4+ lymphopenia in melanoma patients treated with temozolomide: a toxicity with therapeutic implications.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040215
Title: Temozolomide for melanoma: new toxicities and new opportunities.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040215
Title: Temozolomide in the treatment of recurrent malignant glioma.
Journal: Cancer 20040201
Title: Temozolomide in combination with irinotecan for treatment of recurrent malignant glioma.
Journal: American journal of clinical oncology 20040201
Title: Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040201
Title: Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040201
Title: Dual repair modulation reverses Temozolomide resistance in vitro.
Journal: Molecular cancer therapeutics 20040201
Title: Metastatic malignant melanoma presenting as a cavernous sinus syndrome.
Journal: Journal of neurology 20040201
Title: Chemotherapy of anaplastic oligodendroglial tumours.
Journal: Expert opinion on pharmacotherapy 20040201
Title: Bony metastases of anaplastic oligodendroglioma respond to temozolomide.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20040201
Title: [Therapy of malignant melanoma at the stage of distant metastasis].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040201
Title: Temozolomide as prophylaxis for melanoma brain metastases.
Journal: Melanoma research 20040201
Title: Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Journal: Oncogene 20040115
Title: Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer.
Journal: Oncogene 20040108
Title: Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
Journal: Journal of the National Cancer Institute 20040107
Title: Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040101
Title: Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers.
Journal: Investigational new drugs 20040101
Title: Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study.
Journal: Pharmacotherapy 20040101
Title: Volume of residual disease as a predictor of outcome in adult patients with recurrent supratentorial glioblastomas multiforme who are undergoing chemotherapy.
Journal: Journal of neurosurgery 20040101
Title: The role of topotecan in the treatment of brain metastases.
Journal: The oncologist 20040101
Title: Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
Journal: Neuro-oncology 20040101
Title: Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme.
Journal: Neuro-oncology 20040101
Title: A phase II trial of temozolomide and IFN-alpha in patients with advanced renal cell carcinoma.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20040101
Title: Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients.
Journal: Journal of neuro-oncology 20040101
Title: Temozolomide as first-line agent in treating high-grade gliomas: phase II study.
Journal: Journal of neuro-oncology 20040101
Title: Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme.
Journal: Journal of neuro-oncology 20040101
Title: The effect of sequential radiochemotherapy in preirradiated malignant gliomas in a phase II study.
Journal: Journal of neuro-oncology 20040101
Title: Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines.
Journal: Oncology research 20040101
Title: Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
Journal: Anticancer research 20040101
Title: Temozolomide treatment in glioma--experiences in two university hospitals in Finland.
Journal: Acta oncologica (Stockholm, Sweden) 20040101
Title: Role of DNA mismatch repair in apoptotic responses to therapeutic agents.
Journal: Environmental and molecular mutagenesis 20040101
Title: Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.
Journal: Molecular cancer 20040101
Title: Clinical response following adjuvant Temozolomide in a patient with primary cerebral lymphoma.
Journal: Anticancer research 20040101
Title: A two-arm phase II study of temozolomide in patients with advanced gastrointestinal stromal tumors and other soft tissue sarcomas.
Journal: Cancer 20031215
Title: Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
Journal: Cancer chemotherapy and pharmacology 20031201
Title: Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients.
Journal: Cancer chemotherapy and pharmacology 20031201
Title: Response to low dose temozolomide in radiation induced gliomatosis cerebri.
Journal: Medical and pediatric oncology 20031201
Title: Promises and controversies in the management of low-grade glioma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201
Title: Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201
Title: Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201
Title: Carboplatin and teniposide as third-line chemotherapy in patients with recurrent oligodendroglioma or oligoastrocytoma: a phase II study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201
Title: Novel chemotherapeutic agents for the treatment of glioblastoma multiforme.
Journal: Expert opinion on investigational drugs 20031201
Title: Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines.
Journal: British journal of cancer 20031201
Title: Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide.
Journal: Journal of neurosurgery 20031201
Title: State-of-the-art treatment of high-grade brain tumors.
Journal: Seminars in oncology 20031201
Title: Benefits of adjuvant chemotherapy in high-grade gliomas.
Journal: Seminars in oncology 20031201
Title: Can chemotherapy replace radiotherapy in low-grade gliomas? Time for randomized studies.
Journal: Seminars in oncology 20031201
Title: The treatment of elderly patients with high-grade gliomas.
Journal: Seminars in oncology 20031201
Title: Should radiotherapy be standard therapy for brain tumors in the elderly? Cons.
Journal: Seminars in oncology 20031201
Title: The European Organisation for Research and Treatment of Cancer strategy for new drug development in brain tumors.
Journal: Seminars in oncology 20031201
Title: New approach in delivering chemotherapy: locoregional treatment for recurrent glioblastoma (rGBM).
Journal: Journal of experimental & clinical cancer research : CR 20031201
Title: A phase I (tumour site-specific) study of carboplatin and temozolomide in patients with advanced melanoma.
Journal: British journal of cancer 20031117
Title: Phase II trial of intralesional therapy with interleukin-2 in soft-tissue melanoma metastases.
Journal: British journal of cancer 20031103
Title: A mechanistic mathematical model of temozolomide myelosuppression in children with high-grade gliomas.
Journal: Mathematical biosciences 20031101
Title: Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.
Journal: Surgical neurology 20031101
Title: A phase II trial of temozolomide in patients with unresectable or metastatic soft tissue sarcoma.
Journal: Cancer 20031101
Title: Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031101
Title: Temozolomide: realizing the promise and potential.
Journal: Current opinion in oncology 20031101
Title: Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.
Journal: Magnetic resonance imaging 20031101
Title: Bibliography. Current world literature. Therapeutic modalities.
Journal: Current opinion in oncology 20031101
Title: O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma.
Journal: British journal of cancer 20031020
Title: MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine.
Journal: Oncogene 20031016
Title: Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.
Journal: Neurology 20031014
Title: Synthesis of pyrimidinopyridine-triazene conjugates targeted to abl tyrosine kinase.
Journal: Bioorganic & medicinal chemistry letters 20031006
Title: Temozolomide: too early for definitive conclusions.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031001
Title: The role of chemotherapy in brain metastases.
Journal: European journal of cancer (Oxford, England : 1990) 20031001
Title: Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts.
Journal: Molecular cancer therapeutics 20031001
Title: A first feasibility study of temozolomide for Japanese patients with recurrent anaplastic astrocytoma and glioblastoma multiforme.
Journal: International journal of clinical oncology 20031001
Title: Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
Journal: DNA repair 20030918
Title: Repopulating defect of mismatch repair-deficient hematopoietic stem cells.
Journal: Blood 20030901
Title: Role of mismatch repair in the induction of chromosomal aberrations and sister chromatid exchanges in cells treated with different chemotherapeutic agents.
Journal: Cancer chemotherapy and pharmacology 20030901
Title: Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide.
Journal: British journal of cancer 20030901
Title: Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901
Title: Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030901
Title: Treatment of glioblastoma multiforme in the elderly in functionally non-critical areas. Clinical remarks on 22 patients.
Journal: Journal of experimental & clinical cancer research : CR 20030901
Title: Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.
Journal: British journal of cancer 20030804
Title: Summary version of the Standards, Options and Recommendations for the management of adult patients with intracranial glioma (2002).
Journal: British journal of cancer 20030801
Title: Inhibition of angiogenesis by non-toxic doses of temozolomide.
Journal: Anti-cancer drugs 20030801
Title: Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.
Journal: British journal of cancer 20030721
Title: Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells.
Journal: Blood 20030715
Title: Experimental design and sample size determination for testing synergism in drug combination studies based on uniform measures.
Journal: Statistics in medicine 20030715
Title: Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
Journal: Cancer chemotherapy and pharmacology 20030701
Title: Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030701
Title: Randomized phase II study of temozolomide given every 8 hours or daily with either interferon alfa-2b or thalidomide in metastatic malignant melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030701
Title: Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors: chemopotentiation and pharmacological studies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701
Title: Enhancement of platinum-induced cytotoxicity by O6-benzylguanine.
Journal: Molecular cancer therapeutics 20030701
Title: Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615
Title: Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models.
Journal: The Journal of pharmacology and experimental therapeutics 20030601
Title: Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
Journal: European journal of cancer (Oxford, England : 1990) 20030601
Title: Phase II evaluation of temozolomide in metastatic choroidal melanoma.
Journal: Melanoma research 20030601
Title: Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030601
Title: Pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones, a new class of azolotetrazines with potent antitumor activity.
Journal: Bioorganic & medicinal chemistry 20030529
Title: Metabolic activation of temozolomide measured in vivo using positron emission tomography.
Journal: Cancer research 20030515
Title: Irinotecan in the treatment of glioma patients: current and future studies of the North Central Cancer Treatment Group.
Journal: Cancer 20030501
Title: The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
Journal: Cancer 20030501
Title: Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas.
Journal: Cancer 20030501
Title: Temozolomide is active in childhood, progressive, unresectable, low-grade gliomas.
Journal: Journal of pediatric hematology/oncology 20030501
Title: Irinotecan: promising activity in the treatment of malignant glioma.
Journal: Oncology (Williston Park, N.Y.) 20030501
Title: Phase I. Trial of irinotecan and temozolomide in patients with solid tumors.
Journal: Oncology (Williston Park, N.Y.) 20030501
Title: Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma.
Journal: Cancer 20030415
Title: Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules.
Journal: British journal of cancer 20030407
Title: Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030401
Title: Recent developments in the molecular characterization and treatment of oligodendroglial tumors.
Journal: Neuro-oncology 20030401
Title: O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030401
Title: Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly(ADP-ribose) polymerase inhibitor.
Journal: Molecular cancer therapeutics 20030401
Title: Radiochemotherapy of malignant glioma in adults. Clinical experiences.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20030401
Title: DNA repair enzymes and cytotoxic effects of temozolomide: comparative studies between tumor cells and normal cells of the immune system.
Journal: Journal of chemotherapy (Florence, Italy) 20030401
Title: Treatment of brain metastases: a short review of current therapies and the emerging role of temozolomide.
Journal: Clinical advances in hematology & oncology : H&O 20030401
Title: Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
Journal: Neurology 20030311
Title: Atypical presentation and progression of glioblastoma multiforme in a 6-year-old girl: multidisciplinary case report.
Journal: Journal of pediatric hematology/oncology 20030301
Title: Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity.
Journal: Journal of neurosurgery 20030301
Title: Survival with dacarbazine and fotemustine in newly diagnosed glioblastoma multiforme.
Journal: British journal of cancer 20030224
Title: Phase II trial of temozolomide in patients with progressive low-grade glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215
Title: Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids.
Journal: British journal of cancer 20030210
Title: [Interstitial boost and altered fractionation as novel approaches to dose escalation in the radiotherapy of glioblastoma multiforme].
Journal: Orvosi hetilap 20030202
Title: The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.
Journal: The Journal of pharmacology and experimental therapeutics 20030201
Title: A prospective study on glioblastoma in the elderly.
Journal: Cancer 20030201
Title: Plasma and cerebrospinal fluid pharmacokinetics of intravenous temozolomide in non-human primates.
Journal: Journal of neuro-oncology 20030201
Title: Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results.
Journal: Journal of neuro-oncology 20030201
Title: Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma.
Journal: British journal of cancer 20030127
Title: Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.
Journal: Journal of medicinal chemistry 20030116
Title: [Treatment of melanoma].
Journal: Presse medicale (Paris, France : 1983) 20030111
Title: Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Journal: Molecular pharmacology 20030101
Title: Temozolomide in combination with interferon alpha-2b in patients with metastatic melanoma: a phase I dose-escalation study.
Journal: Cancer 20030101
Title: Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
Journal: The oncologist 20030101
Title: Pharmacokinetics of radiolabelled anticancer drugs for positron emission tomography.
Journal: Current pharmaceutical design 20030101
Title: Advances in molecular therapies in patients with brain tumors.
Journal: Cancer control : journal of the Moffitt Cancer Center 20030101
Title: Current chemotherapy for glioblastoma.
Journal: Cancer journal (Sudbury, Mass.) 20030101
Title: Survival of patients with recurrent malignant glioma treated with temozolomide: a retrospective observational study.
Journal: Drugs in R&D 20030101
Title: Pharmacology of oral chemotherapy agents.
Journal: Clinical journal of oncology nursing 20030101
Title: Medication sheets for patients. Oral chemotherapy.
Journal: Clinical journal of oncology nursing 20030101
Title: Guidelines for the treatment of oligodendroglioma: an evidence-based medicine approach.
Journal: Forum (Genoa, Italy) 20030101
Title: New drugs and combinations for malignant glioma.
Journal: Forum (Genoa, Italy) 20030101
Title: Health-related quality of life in patients with advanced metastatic melanoma: results of a randomized phase III study comparing temozolomide with dacarbazine.
Journal: Cancer investigation 20030101
Title: Quality of life, at what cost?
Journal: Cancer investigation 20030101
Title: Temozolomide in radio-chemotherapy combined treatment for newly-diagnosed glioblastoma multiforme: phase II clinical trial.
Journal: Anticancer research 20030101
Title: Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.
Journal: Journal of the National Cancer Institute 20021218
Title: Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215
Title: Immunophenotypical markers, ultrastructure and chemosensitivity profile of metastatic melanoma cells.
Journal: Cancer letters 20021205
Title: Antitumor imidazotetrazines. 40. Radiosyntheses of [4-11C-carbonyl]- and [3-N-11C-methyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) for positron emission tomography (PET) studies.
Journal: Journal of medicinal chemistry 20021205
Title: Antitumor imidazotetrazines. 41. Conjugation of the antitumor agents mitozolomide and temozolomide to peptides and lexitropsins bearing DNA major and minor groove-binding structural motifs.
Journal: Journal of medicinal chemistry 20021205
Title: Recurrent malignant glioma in adults.
Journal: Current treatment options in oncology 20021201
Title: Developing therapeutic pharmaceuticals for the treatment of soft-tissue sarcomas.
Journal: Expert opinion on investigational drugs 20021201
Title: New drugs for the treatment of cancer, 1990-2001.
Journal: The Israel Medical Association journal : IMAJ 20021201
Title: Temozolomide and cisplatin in the treatment of leptomeningeal metastatic involvement from melanoma: a case report.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20021201
Title: [Complete response of cerebral metastasic melanoma after a combined treatment of radiotherapy and temozolomide].
Journal: Medicina clinica 20021130
Title: Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure.
Journal: Journal of medicinal chemistry 20021107
Title: Oral cancer treatment: developments in chemotherapy and beyond.
Journal: British journal of cancer 20021021
Title: Treatment of paediatric pontine glioma with oral trophosphamide and etoposide.
Journal: British journal of cancer 20021021
Title: Treatment of disseminated ocular melanoma with sequential fotemustine, interferon alpha, and interleukin 2.
Journal: British journal of cancer 20021007
Title: Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
Journal: Glia 20021001
Title: [Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20021001
Title: A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy.
Journal: Neuro-oncology 20021001
Title: Treatment of leptomeningeal relapse of medulloblastoma with temozolomide.
Journal: Journal of pediatric hematology/oncology 20021001
Title: A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021001
Title: Chemotherapy for the treatment of metastatic brain tumors.
Journal: Expert review of anticancer therapy 20021001
Title: Advances in diagnosis and management of oligodendroglioma.
Journal: Expert review of anticancer therapy 20021001
Title: Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report.
Journal: American journal of clinical oncology 20021001
Title: Systemic chemotherapy for the treatment of metastatic melanoma.
Journal: Seminars in oncology 20021001
Title: The treatment of brain metastases from malignant melanoma.
Journal: Seminars in oncology 20021001
Title: Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells.
Journal: Cancer gene therapy 20020901
Title: Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020901
Title: Small-sample inference for incomplete longitudinal data with truncation and censoring in tumor xenograft models.
Journal: Biometrics 20020901
Title: Base excision repair as a therapeutic target in colon cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
Title: The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
Title: Case report: a patient with primary CNS lymphoma treated with temozolomide to complete response.
Journal: Journal of neuro-oncology 20020901
Title: O6-benzylguanine-mediated enhancement of chemotherapy.
Journal: Molecular cancer therapeutics 20020901
Title: Weekly gemcitabine plus Epirubicin as effective chemotherapy for advanced pancreatic cancer: a multicenter phase II study.
Journal: British journal of cancer 20020827
Title: Effect of O6-(4-bromothenyl)guanine on different temozolomide schedules in a human melanoma xenograft model.
Journal: International journal of cancer 20020810
Title: Phase I study of temozolomide in relapsed/refractory acute leukemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801
Title: Multifaceted resistance of gliomas to temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020801
Title: A phase II trial of oral temozolomide in patients with metastatic renal cell cancer.
Journal: Cancer chemotherapy and pharmacology 20020801
Title: Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
Journal: Cancer 20020801
Title: Treatment of newly diagnosed glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715
Title: Promising survival and concomitant radiation plus temozolomide followed by adjuvant temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715
Title: Pharmacological strategies to increase the antitumor activity of methylating agents.
Journal: Current medicinal chemistry 20020701
Title: Temozolomide-induced flare in high-grade gliomas: a new clinical entity.
Journal: Internal medicine journal 20020701
Title: Heterogeneity of O6-alkylguanine DNA-alkyltransferase expression in human breast tumours.
Journal: British journal of cancer 20020605
Title: Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Journal: Cancer research 20020601
Title: Temozolomide plus thalidomide in patients with advanced melanoma: results of a dose-finding trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020601
Title: First-line therapy with temozolomide induces regression of primary CNS lymphoma.
Journal: Neurology 20020528
Title: [Treatment of recidive malignant gliomas with temozolomide].
Journal: Orvosi hetilap 20020526
Title: Clinical relevance of MGMT in the treatment of cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20020501
Title: Temozolomide as second-line chemotherapy for relapsed gliomas.
Journal: Journal of neuro-oncology 20020501
Title: Temozolomide in non-small-cell lung cancer: preliminary results of a phase II trial in previously treated patients.
Journal: Clinical lung cancer 20020501
Title: Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for pre-phase I positron emission tomography studies in cancer patients.
Journal: British journal of cancer 20020408
Title: Photodynamic therapy of DNA mismatch repair-deficient and -proficient tumour cells.
Journal: British journal of cancer 20020408
Title: Effect of temozolomide on central nervous system relapse in patients with advanced melanoma.
Journal: Melanoma research 20020401
Title: Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group.
Journal: Journal of cancer research and clinical oncology 20020401
Title: A phase II EORTC study of temozolomide in patients with malignant pleural mesothelioma.
Journal: European journal of cancer (Oxford, England : 1990) 20020401
Title: Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
Journal: Biochemical pharmacology 20020401
Title: Synthesis and antibacterial activity of dual-action agents of a beta-lactam antibiotic with cytotoxic agent mitozolomide or temozolomide.
Journal: European journal of medicinal chemistry 20020401
Title: The use of temozolomide in recurrent malignant gliomas.
Journal: Cancer treatment reviews 20020401
Title: Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site.
Journal: Blood 20020315
Title: Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.
Journal: Cancer research 20020315
Title: Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301
Title: Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301
Title: NICE verdict on Temozolomide: where next?
Journal: British journal of cancer 20020212
Title: A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma.
Journal: British journal of cancer 20020212
Title: Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020115
Title: A phase II study of extended low-dose temozolomide in recurrent malignant gliomas.
Journal: Neuro-oncology 20020101
Title: Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer.
Journal: Drugs & aging 20020101
Title: Temozolomide in glioblastoma multiforme of the elderly.
Journal: Tumori 20020101
Title: Combined radiotherapy and temozolomide in patients with recurrent high grade glioma.
Journal: Tumori 20020101
Title: Concomitant radiotherapy and metronomic temozolomide in pediatric high-risk brain tumors.
Journal: Neoplasma 20020101
Title: Temozolomide in patients with glioblastoma at second relapse after first line nitrosourea-procarbazine failure: a phase II study.
Journal: Oncology 20020101
Title: Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution.
Journal: International journal of clinical pharmacology research 20020101
Title: [Treatment of anaplastic astrocytomas and glioblastomas in children by the use of temozolomide (TMZ)].
Journal: Voprosy onkologii 20020101
Title: Search of antimicrobial activity of selected non-antibiotic drugs.
Journal: Acta poloniae pharmaceutica 20020101
Title: Role of cytochrome P450 isoenzymes in metabolism of O(6)-benzylguanine: implications for dacarbazine activation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Title: Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
Journal: Journal of neuro-oncology 20011201
Title: Low-grade gliomas.
Journal: Current treatment options in oncology 20011201
Title: Adults with newly diagnosed high-grade gliomas.
Journal: Current treatment options in oncology 20011201
Title: Possible efficacy of temozolomide in a patient with gliomatosis cerebri.
Journal: Neurology 20011127
Title: New strategy developments in brain tumor therapy.
Journal: Current pharmaceutical design 20011101
Title: Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.
Journal: Neuro-oncology 20011001
Title: Targeting DNA mismatch repair for radiosensitization.
Journal: Seminars in radiation oncology 20011001
Title: Treatment of metastatic melanoma in the brain with temozolomide and thalidomide.
Journal: The Lancet. Oncology 20011001
Title: New perspectives for the diagnosis and treatment of oligodendroglioma.
Journal: Expert review of anticancer therapy 20011001
Title: Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.
Journal: Cancer gene therapy 20010901
Title: Current and future developments in the use of temozolomide for the treatment of brain tumours.
Journal: The Lancet. Oncology 20010901
Title: Treatment of brain metastases of malignant melanoma with temozolomide.
Journal: The New England journal of medicine 20010823
Title: Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.
Journal: International journal of oncology 20010801
Title: hMSH3 overexpression and cellular response to cytotoxic anticancer agents.
Journal: Carcinogenesis 20010801
Title: Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
Journal: Cancer research 20010801
Title: Temozolomide: the effect of once- and twice-a-day dosing on tumor tissue levels of the DNA repair protein O(6)-alkylguanine-DNA-alkyltransferase.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010801
Title: Temozolomide for recurrent high-grade glioma.
Journal: Seminars in oncology 20010801
Title: Chemotherapy for the treatment of oligodendroglial tumors.
Journal: Seminars in oncology 20010801
Title: New approaches for temozolomide therapy: use in newly diagnosed glioma.
Journal: Seminars in oncology 20010801
Title: Temozolomide in combination with other cytotoxic agents.
Journal: Seminars in oncology 20010801
Title: Temozolomide for treating brain metastases.
Journal: Seminars in oncology 20010801
Title: Future directions for temozolomide therapy.
Journal: Seminars in oncology 20010801
Title: Temozolomide chemotherapy in recurrent oligodendroglioma.
Journal: Neurology 20010724
Title: Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470.
Journal: Cancer research 20010715
Title: CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release.
Journal: Oncogene 20010712
Title: An Australian experience with temozolomide for the treatment of recurrent high grade gliomas.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20010701
Title: Kinetics of neutrophil production in normal and neutropenic animals during the response to filgrastim (r-metHu G-CSF) or filgrastim SD/01 (PEG-r-metHu G-CSF).
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010701
Title: Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine.
Journal: Cancer chemotherapy and pharmacology 20010701
Title: Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
Journal: European journal of haematology 20010701
Title: A phase II trial of temozolomide for patients with recurrent or progressive brain metastases.
Journal: Journal of neuro-oncology 20010701
Title: Heterogeneous methylation of the O(6)-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines.
Journal: International journal of oncology 20010601
Title: Metastatic melanoma.
Journal: Current treatment options in oncology 20010601
Title: Temozolomide: a novel oral alkylating agent.
Journal: Expert review of anticancer therapy 20010601
Title: Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.
Journal: Cancer research 20010515
Title: Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells.
Journal: Mutation research 20010510
Title: Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010501
Title: Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010501
Title: Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.
Journal: Cell death and differentiation 20010501
Title: Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010401
Title: Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.
Journal: Cancer chemotherapy and pharmacology 20010401
Title: Design of a chimeric 3-methyl-1,2,3-triazene with mixed receptor tyrosine kinase and DNA damaging properties: a novel tumor targeting strategy.
Journal: The Journal of pharmacology and experimental therapeutics 20010301
Title: Development and application of a sensitive and rapid immunoassay for the quantitation of N7-methyldeoxyguanosine in DNA samples.
Journal: Chemical research in toxicology 20010301
Title: p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.
Journal: Cancer research 20010301
Title: Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells.
Journal: Gene therapy 20010301
Title: Atypical teratoid/rhabdoid tumors in adult patients: case report and review of the literature.
Journal: Journal of neuro-oncology 20010301
Title: Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010201
Title: Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010201
Title: Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010201
Title: Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010201
Title: Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20010101
Title: High-performance liquid chromatographic analysis and stability of anti-tumor agent temozolomide in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20010101
Title: Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients.
Journal: Oncology 20010101
Title: Thalidomide as an anti-angiogenic agent in relapsed gliomas.
Journal: Journal of neuro-oncology 20010101
Title: The effectiveness and cost-effectiveness of temozolomide for the treatment of recurrent malignant glioma: a rapid and systematic review.
Journal: Health technology assessment (Winchester, England) 20010101
Title: Mapping therapeutic response in a patient with malignant glioma.
Journal: Journal of computer assisted tomography 20010101
Title: Late recurrence of a primitive neuro-ectodermal tumor.
Journal: Oncology 20010101
Title: Controversies in the management of brain metastases: the role of chemotherapy.
Journal: Forum (Genoa, Italy) 20010101
Title: Therapeutic management of refractory or relapsed primary central nervous system lymphomas.
Journal: Annals of hematology 20010101
Title: Temozolomide (Temodar).
Journal: Clinical journal of oncology nursing 20010101
Title: Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.
Journal: Cancer research 20001001
Title: Temozolomide and treatment of malignant glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20000701
Title: Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20000701
Title: Temozolomide in malignant gliomas.
Journal: Seminars in oncology 20000601
Title: Phase II study of temozolomide in patients with relapsing high grade glioma and poor performance status.
Journal: Medical oncology (Northwood, London, England) 20000501
Title: In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
Journal: Carcinogenesis 20000401
Title: Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20000101
Title: Tetrazepinones are equally cytotoxic to Mer+ and Mer- human tumor cell lines.
Journal: The Journal of pharmacology and experimental therapeutics 19990201
Title: Cisplatin increases sensitivity of human leukemic blasts to triazene compounds.
Journal: Journal of chemotherapy (Florence, Italy) 19950601
Title: Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression.
Journal: The Journal of clinical endocrinology and metabolism
Title: Tentori L, et al. Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site. Blood. 2002 Mar 15;99(6):2241-4.
Title: Mathieu V, et al. Combining Anti-Human VEGF with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model. Neoplasia. 2008 Dec;10(12):1383-92.
Title: Perazzoli G, et al. Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression. PLoS One. 2015 Oct 8;10(10):e0140131.
