Home Other Building Blocks 942183-80-4
942183-80-4,MFCD11878503
Catalog No.:AA00394M

942183-80-4 | SCH772984

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$52.00   $36.00
- +
2mg
98%
in stock  
$77.00   $54.00
- +
5mg
98%
in stock  
$132.00   $93.00
- +
10mg
98%
in stock  
$198.00   $139.00
- +
25mg
95%
in stock  
$366.00   $257.00
- +
50mg
98%
in stock  
$591.00   $414.00
- +
100mg
95%
in stock  
$1,098.00   $769.00
- +
250mg
95%
in stock  
$1,308.00   $915.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00394M
Chemical Name:
SCH772984
CAS Number:
942183-80-4
Molecular Formula:
C33H33N9O2
Molecular Weight:
587.6742
MDL Number:
MFCD11878503
SMILES:
O=C(N1CCN(CC1)c1ccc(cc1)c1ncccn1)CN1CC[C@H](C1)C(=O)Nc1ccc2c(c1)c(n[nH]2)c1ccncc1
Properties
Computed Properties
 
Complexity:
957  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
2.5  

Literature

Title: Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.

Journal: Journal of medicinal chemistry 20180614

Title: Dysregulation of MAP Kinase Signaling Pathways Including p38MAPK, SAPK/JNK, and ERK1/2 in Cultured Rat Cerebellar Astrocytes Exposed to Diphenylarsinic Acid.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170401

Title: Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2.

Journal: Journal of medicinal chemistry 20150611

Title: Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

Journal: Cancer discovery 20130701

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Tags:942183-80-4 Molecular Formula|942183-80-4 MDL|942183-80-4 SMILES|942183-80-4 SCH772984