Title: Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors.
Journal: Chemico-biological interactions20180325
Title: Betulinyl Sulfamates as Anticancer Agents and Radiosensitizers in Human Breast Cancer Cells.
Journal: International journal of molecular sciences20151101
Title: Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters20150815
Title: Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.
Journal: Journal of natural products20150522
Title: Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.
Journal: PloS one20150101
Title: Betulin derivatives impair Leishmania braziliensis viability and host-parasite interaction.
Journal: Bioorganic & medicinal chemistry20141101
Title: Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.
Journal: Antimicrobial agents and chemotherapy20140401
Title: Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives.
Journal: PloS one20140101
Title: A novel one-step microbial transformation of betulin to betulinic acid catalysed by Cunninghamella blakesleeana.
Journal: Food chemistry20130101
Title: X-ray diffraction and infrared spectroscopy of N,N-dimethylformamide and dimethyl sulfoxide solvatomorphs of betulonic acid.
Journal: Journal of pharmaceutical sciences20121201
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry20121115
Title: A practical synthesis of betulonic acid using selective oxidation of betulin on aluminium solid support.
Journal: Molecules (Basel, Switzerland)20121009
Title: Effect of triterpene derivatives on the total hepatocyte count in the liver of rats with toxic hepatitis.
Journal: Bulletin of experimental biology and medicine20121001
Title: A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products.
Journal: The Biochemical journal20120901
Title: Source correlation of biomarkers in a mangrove ecosystem on Santa Catarina Island in southern Brazil.
Journal: Anais da Academia Brasileira de Ciencias20120901
Title: Extraction of betulin, trimyristin, eugenol and carnosic acid using water-organic solvent mixtures.
Journal: Molecules (Basel, Switzerland)20120803
Title: Betulin as an antitumor agent tested in vitro on A431, HeLa and MCF7, and as an angiogenic inhibitor in vivo in the CAM assay.
Journal: Natural product communications20120801
Title: Constituents of twig bark of pear cultivars (Pyrus species).
Journal: Natural product communications20120801
Title: Synthesis and cytotoxicity of lupane-type triterpenoid glyceryl esters.
Journal: Bioorganic & medicinal chemistry letters20120715
Title: Alkylidene branched lupane derivatives: synthesis and antitumor activity.
Journal: European journal of medicinal chemistry20120701
Title: Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.
Journal: Bioorganic & medicinal chemistry20120601
Title: In vitro cytotoxicity of cyclodextrin-bonded birch bark extract.
Journal: Planta medica20120601
Title: Chemical constituents of the ethyl acetate extract of Belamcanda chinensis (L.) DC roots and their antitumor activities.
Journal: Molecules (Basel, Switzerland)20120524
Title: Comparison of the triterpenoid content of berries and leaves of lingonberry Vaccinium vitis-idaea from Finland and Poland.
Journal: Journal of agricultural and food chemistry20120516
Title: Hydroxylation of the triterpenoid dipterocarpol with CYP106A2 from Bacillus megaterium.
Journal: The FEBS journal20120501
Title: [Chemical constituents of Dolomiaea souliei].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20120501
Title: Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD.
Journal: Journal of natural products20120427
Title: Lupane-type pentacyclic triterpenes in Langmuir monolayers: a synchrotron radiation scattering study.
Journal: Langmuir : the ACS journal of surfaces and colloids20120320
Title: Distribution and expression characteristics of triterpenoids and OSC genes in white birch (Betula platyphylla suk.).
Journal: Molecular biology reports20120301
Title: A comparison investigation on the solubilization of betulin and betulinic acid in cyclodextrin derivatives.
Journal: Natural product communications20120301
Title: Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.
Journal: Diabetologia20120201
Title: Simultaneous quantification of five marker compounds of Betula utilis stem bark using a validated high-performance thin-layer chromatography method.
Journal: Journal of separation science20120201
Title: Antiproliferative activity of Luehea candicans Mart. et Zucc. (Tiliaceae).
Journal: Natural product research20120101
Title: Study of the betulin molecule in a water environment; ab initio and molecular simulation calculations.
Journal: Journal of molecular modeling20120101
Title: Physico-chemical comparison of betulinic acid, betulin and birch bark extract and in vitro investigation of their cytotoxic effects towards skin epidermoid carcinoma (A431), breast carcinoma (MCF7) and cervix adenocarcinoma (HeLa) cell lines.
Journal: Natural product research20120101
Title: Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark.
Journal: Journal of natural medicines20120101
Title: Bioguided isolation of pentacyclic triterpenes from the leaves of Alstonia scholaris (Linn.) R. Br. growing in Egypt.
Journal: Natural product research20120101
Title: New icetexane diterpenes with intestinal α-glucosidase inhibitory and free-radical scavenging activity isolated from Premna tomentosa roots.
Journal: Fitoterapia20120101
Title: Cancer metabolism: current perspectives and future directions.
Journal: Cell death & disease20120101
Title: Effects of Corni fructus on ovalbumin-induced airway inflammation and airway hyper-responsiveness in a mouse model of allergic asthma.
Journal: Journal of inflammation (London, England)20120101
Title: Low-dose Cd induces hepatic gene hypermethylation, along with the persistent reduction of cell death and increase of cell proliferation in rats and mice.
Journal: PloS one20120101
Title: Nonsterol Triterpenoids as Major Constituents of Olea europaea.
Journal: Journal of lipids20120101
Title: Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.
Journal: PloS one20120101
Title: Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds.
Journal: Evidence-based complementary and alternative medicine : eCAM20120101
Title: Evaluation and differentiation of the Betulaceae birch bark species and their bioactive triterpene content using analytical FT-vibrational spectroscopy and GC-MS.
Journal: Chemistry Central journal20120101
Title: In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds.
Journal: Evidence-based complementary and alternative medicine : eCAM20120101
Title: Lignans and triterpenes from the root of Pseuderanthemum carruthersii var. atropurpureum.
Journal: Chemical & pharmaceutical bulletin20120101
Title: Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoids, and their synthetic derivatives.
Journal: Bioorganicheskaia khimiia20120101
Title: CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.
Journal: Plant & cell physiology20111201
Title: Cloning, expression, characterization and inhibition studies on trypanothione synthetase, a drug target enzyme, from Leishmania donovani.
Journal: Biological chemistry20111201
Title: Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography.
Journal: Chemistry & biodiversity20111201
Title: Intrinsically microporous polyesters from betulin - toward renewable materials for gas separation made from birch bark.
Journal: Macromolecular rapid communications20111115
Title: Efficient synthesis of lupane-type saponins via gold(I)-catalyzed glycosylation with glycosyl ortho-alkynylbenzoates as donors.
Journal: Organic letters20111021
Title: Novel betulin derivatives as antileishmanial agents with mode of action targeting type IB DNA topoisomerase.
Journal: Molecular pharmacology20111001
Title: [Study on the triterpenoids from the fruits of Ligustrum lucidum].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20111001
Title: Improvement of the cytotoxicity and tumor selectivity of glycyrrhetinic acid by derivatization with bifunctional amino acids.
Journal: Archiv der Pharmazie20110801
Title: Birch bark extract as therapy for chronic hepatitis C--a pilot study.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20110715
Title: Toxicity of betulin derivatives and in vitro effect on promastigotes and amastigotes of Leishmania infantum and L. donovani.
Journal: The Journal of antibiotics20110701
Title: Lignans and other constituents from the roots of the Vietnamese medicinal plant Pseuderanthemum palatiferum.
Journal: Planta medica20110601
Title: Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.
Journal: Bioorganic & medicinal chemistry letters20110415
Title: Lupane triterpenoids--betulin and betulinic acid derivatives induce apoptosis in tumor cells.
Journal: Investigational new drugs20110401
Title: Anti-angiogenic effects of betulinic acid administered in nanoemulsion formulation using chorioallantoic membrane assay.
Journal: Journal of biomedical nanotechnology20110401
Title: Allobetulin and its derivatives: synthesis and biological activity.
Journal: Molecules (Basel, Switzerland)20110314
Title: Betulin and betulinic acid attenuate ethanol-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS), cytokine (TNF-α, TGF-β) production and by influencing intracellular signaling.
Journal: Toxicology20110227
Title: Hypoglycemic evaluation of a new triterpene and other compounds isolated from Euclea undulata Thunb. var. myrtina (Ebenaceae) root bark.
Journal: Journal of ethnopharmacology20110216
Title: Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques.
Journal: Cell metabolism20110105
Title: Biotransformation optimization of betulin into betulinic acid production catalysed by cultured Armillaria luteo-virens Sacc ZJUQH100-6 cells.
Journal: Journal of applied microbiology20110101
Title: Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels.
Journal: Current pharmaceutical biotechnology20110101
Title: Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Journal: Bioorganic & medicinal chemistry letters20110101
Title: Synthesis, encapsulation and antitumor activity of new betulin derivatives.
Journal: Archiv der Pharmazie20110101
Title: Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark.
Journal: Malaria journal20110101
Title: Antihistaminic effect of Bauhinia racemosa leaves.
Journal: Journal of young pharmacists : JYP20110101
Title: Prospective randomized clinical trial comparing phytotherapy with potassium citrate in management of minimal burden (≤8 mm) nephrolithiasis.
Journal: Urology annals20110101
Title: Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation.
Journal: Journal of lipids20110101
Title: [Synthesis and antitumor activity of betulin, erythrodiol and uvaol aminopropoxy derivatives].
Journal: Bioorganicheskaia khimiia20110101
Title: Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions.
Journal: Radiation oncology (London, England)20110101
Title: 2D-QSAR model development and analysis on variant groups of anti-tuberculosis drugs.
Journal: Bioinformation20110101
Title: The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.
Journal: Retrovirology20110101
Title: Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells.
Journal: Pharmacological reports : PR20110101
Title: Bioactive constituents and medicinal importance of genus Alnus.
Journal: Pharmacognosy reviews20110101
Title: Triterpenoids from Schleichera oleosa of Darjeeling Foothills and Their Antimicrobial Activity.
Journal: Indian journal of pharmaceutical sciences20110101
Title: Antimicrobial and antifungal activities of Cordia dichotoma (Forster F.) bark extracts.
Journal: Ayu20110101
Title: [Structural and functional characteristics of betulin derivatives].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]20110101
Title: Immunomodulatory effects of betulinic acid from the bark of white birch on mice.
Journal: Journal of veterinary science20101201
Title: Evaluation of chemical constituents and antinociceptive properties of Myricaria elegans Royle.
Journal: Chemistry & biodiversity20101201
Title: Effects of Phyllanthus reticulatus on lipid profile and oxidative stress in hypercholesterolemic albino rats.
Journal: Indian journal of pharmacology20101201
Title: Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom.
Journal: Molecules (Basel, Switzerland)20101112
Title: [Advances in the study of structural modifications and biological activities of betulinic acids].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20101101
Title: 3β-Acet-oxy-lup-20(29)-en-28-yl 1H-1,2,4-tri-azole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online20101101
Title: Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.
Journal: Biochemical pharmacology20101015
Title: Synthesis, cytotoxicity and liposome preparation of 28-acetylenic betulin derivatives.
Journal: Bioorganic & medicinal chemistry20101015
Title: Topical treatment of necrotising herpes zoster with betulin from birch bark.
Journal: Forschende Komplementarmedizin (2006)20101001
Title: Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Journal: Toxins20101001
Title: Conjugates of betulin derivatives with AZT as potent anti-HIV agents.
Journal: Bioorganic & medicinal chemistry20100901
Title: Synthesis and anticancer activity of novel betulinic acid and betulin derivatives.
Journal: Archiv der Pharmazie20100801
Title: Betulin and ursolic acid synthetic derivatives as inhibitors of Papilloma virus.
Journal: Bioorganic & medicinal chemistry letters20100715
Title: Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells.
Journal: Journal of medicinal chemistry20100708
Title: Betulin induces mitochondrial cytochrome c release associated apoptosis in human cancer cells.
Journal: Molecular carcinogenesis20100701
Title: Xanthones, biflavanones and triterpenes from Pentadesma grandifolia (Clusiaceae): structural determination and bioactivity.
Journal: Natural product communications20100701
Title: 3β-Hy-droxy-lup-20(29)-en-28-yl 1H-imidazole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online20100701
Title: Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.
Journal: Bioorganic & medicinal chemistry20100615
Title: Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20100601
Title: Carbamate derivatives of betulinic acid and betulin with selective cytotoxic activity.
Journal: Bioorganic & medicinal chemistry letters20100601
Title: [Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20100501
Title: [Studies on the triterpenoids constituents from Phyllodium elegans].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100501
Title: In vitro anticancer studies of alpha- and beta-D-glucopyranose betulin anomers.
Journal: Chemico-biological interactions20100429
Title: Antiprotozoal activity of betulinic acid derivatives.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20100401
Title: Synthesis and biological evaluation of antitumor-active gamma-butyrolactone substituted betulin derivatives.
Journal: Bioorganic & medicinal chemistry20100401
Title: A pentacyclic triterpene from Litchi chinensis.
Journal: Natural product communications20100401
Title: [Chemical constituents from fruits of Ligustrum lucidum].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20100401
Title: Synthesis of betulin derivatives and the determination of their relative lipophilicities using reversed-phase thin-layer chromatography.
Journal: Biomedical chromatography : BMC20100301
Title: Anti-HIV-1 and anti-inflammatory lupanes from the leaves, twigs, and resin of Garcinia hanburyi.
Journal: Planta medica20100301
Title: Anti-leishmanial activity of betulin derivatives.
Journal: The Journal of antibiotics20100301
Title: An anti-influenza component of the bark of Alnus japonica.
Journal: Archives of pharmacal research20100301
Title: Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives.
Journal: Bioorganic & medicinal chemistry20100215
Title: Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20100201
Title: Synthesis and biological evaluation of antitumour-active betulin derivatives.
Journal: Bioorganic & medicinal chemistry20100201
Title: Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
Journal: Journal of medicinal chemistry20100114
Title: Analgesic and anti-inflammatory effects of Cassia siamea Lam. stem bark extracts.
Journal: Journal of ethnopharmacology20100108
Title: Triterpenes promote keratinocyte differentiation in vitro, ex vivo and in vivo: a role for the transient receptor potential canonical (subtype) 6.
Journal: The Journal of investigative dermatology20100101
Title: Synthesis of a molecularly imprinted polymer for the solid-phase extraction of betulin and betulinic acid from plane bark.
Journal: Phytochemical analysis : PCA20100101
Title: Molluscicides from some common medicinal plants of eastern Uttar Pradesh, India.
Journal: Journal of applied toxicology : JAT20100101
Title: [A one-step approach to the synthesis of germanicane triterpenoids from allobetulin].
Journal: Bioorganicheskaia khimiia20100101
Title: Possible fungistatic implications of betulin presence in betulaceae plants and their hymenochaetaceae parasitic fungi.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20100101
Title: Prevention and treatment of intertrigo in large skin folds of adults: a systematic review.
Journal: BMC nursing20100101
Title: [Synthesis, modifications, and antimicrobial activity of the methylpiperazinyl amides of triterpenic acids].
Journal: Bioorganicheskaia khimiia20100101
Title: [Synthesis of new olean-18(19)-ene derivatives from allobetulin].
Journal: Bioorganicheskaia khimiia20100101
Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.
Journal: Journal of ethnobiology and ethnomedicine20100101
Title: Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel.
Journal: Journal of inflammation (London, England)20100101
Title: [Synthesis of triterpenoid acylates - an effective reproduction inhibitors of influenza A (H1N1) and papilloma viruses].
Journal: Bioorganicheskaia khimiia20100101
Title: Diuretic and natriuretic activity of two mistletoe species in rats.
Journal: Pharmacognosy research20100101
Title: Triterpenes from Euphorbia rigida.
Journal: Pharmacognosy research20100101
Title: Hygrophila spinosa: A comprehensive review.
Journal: Pharmacognosy reviews20100101
Title: Trace quantification of 1-octacosanol and 1-triacontanol and their main metabolites in plasma by liquid-liquid extraction coupled with gas chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20091215
Title: Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy.
Journal: Planta medica20091201
Title: Betulin elicits anti-cancer effects in tumour primary cultures and cell lines in vitro.
Journal: Basic & clinical pharmacology & toxicology20091201
Title: The hunt for natural skin whitening agents.
Journal: International journal of molecular sciences20091201
Title: Betulin-derived compounds as inhibitors of alphavirus replication.
Journal: Journal of natural products20091101
Title: Quantitative determination of steroids in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus.
Journal: Se pu = Chinese journal of chromatography20091101
Title: Bioactivity-guided isolation of cytotoxic constituents from stem-bark of Premna tomentosa.
Journal: Bioorganic & medicinal chemistry letters20091001
Title: Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity.
Journal: Bioorganic & medicinal chemistry20090901
Title: Chemical Constituents of the Roots of Euphorbia micractina.
Journal: Journal of natural products20090901
Title: Study on determination of pentacyclic triterpenoids in Chaenomeles by HPLC-ELSD.
Journal: Journal of chromatographic science20090901
Title: Antifungal activity of Eugenia umbelliflora against dermatophytes.
Journal: Natural product communications20090901
Title: [A novel azo-type compound from Dendrolobium triangulare].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20090901
Title: 19β,28-Ep-oxy-18α-olean-3β-ol.
Journal: Acta crystallographica. Section E, Structure reports online20090901
Title: Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells.
Journal: Bioorganic & medicinal chemistry letters20090815
Title: Optimization of subcritical fluid extraction of bioactive compounds using Hansen solubility parameters.
Journal: Journal of food science20090801
Title: 3,28-Diacet-oxy-29-bromo-betulin.
Journal: Acta crystallographica. Section E, Structure reports online20090801
Title: Phytochemical analyses and gastroprotective effects of Eugenia umbelliflora (Myrtaceae) on experimental gastric ulcers.
Journal: Natural product communications20090701
Title: Triterpenoids from the roots of Pterospermum heterophyllum Hance.
Journal: Journal of Asian natural products research20090701
Title: Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
Journal: Molecules (Basel, Switzerland)20090604
Title: Optimization of ultrasonic-assisted extraction (UAE) of betulin from white birch bark using response surface methodology.
Journal: Ultrasonics sonochemistry20090601
Title: Analysis of Salvia coccinea from Jamaican populations.
Journal: Natural product communications20090601
Title: Sustained release of microbicides by newly engineered vaginal rings.
Journal: AIDS (London, England)20090515
Title: Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines.
Journal: Molecules (Basel, Switzerland)20090424
Title: Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products.
Journal: Bioorganic & medicinal chemistry letters20090415
Title: Synthesis and cytotoxicity of 2-cyano-28-hydroxy-lup-1-en-3-ones.
Journal: Bioorganic & medicinal chemistry letters20090415
Title: Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins.
Journal: Bioorganic & medicinal chemistry20090301
Title: Treatment of actinic keratoses with a novel betulin-based oleogel. A prospective, randomized, comparative pilot study.
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG20090201
Title: Anti-cancer effect of Betulin on a human lung cancer cell line: a pharmacoproteomic approach using 2 D SDS PAGE coupled with nano-HPLC tandem Mass Spectrometry.
Journal: Planta medica20090201
Title: Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis.
Journal: International immunopharmacology20090201
Title: Identification and isolation of pharmacologically active triterpenes in Betuale cortex, Betula pendula Roth., Betulaceae.
Journal: Bosnian journal of basic medical sciences20090201
Title: Analysis of pentacyclic triterpenes by LC-MS. A comparative study between APCI and APPI.
Journal: Journal of mass spectrometry : JMS20090101
Title: Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins.
Journal: Journal of natural products20090101
Title: Analgesic and anti-inflammatory activities of Torenia concolor Lindley var. formosana Yamazaki and betulin in mice.
Journal: The American journal of Chinese medicine20090101
Title: Betulin is a potent anti-tumor agent that is enhanced by cholesterol.
Journal: PloS one20090101
Title: [Synthesis of olean-18(19)-ene derivatives from betulin].
Journal: Bioorganicheskaia khimiia20090101
Title: [New betulin derivatives in combination with rimantadine for inhibition of influenza virus reproduction].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]20090101
Title: A preliminary pharmacokinetic study of betulin, the main pentacyclic triterpene from extract of outer bark of birch (Betulae alba cortex).
Journal: Molecules (Basel, Switzerland)20081218
Title: Identification of new molecules extracted from Quercus suber L. cork.
Journal: Comptes rendus biologies20081101
Title: Betulin binds to gamma-aminobutyric acid receptors and exerts anticonvulsant action in mice.
Journal: Pharmacology, biochemistry, and behavior20081001
Title: Interaction of the globular domain of human C1q with Salmonella typhimurium lipopolysaccharide.
Journal: Biochimica et biophysica acta20080901
Title: Comparison with various parts of Broussonetia papyrifera as to the antinociceptive and anti-inflammatory activities in rodents.
Journal: Bioscience, biotechnology, and biochemistry20080901
Title: [Studies on chemical constituents from roots of Pterospermum heterophyllum].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080801
Title: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
Journal: Journal of medicinal chemistry20080626
Title: Investigation of Indian diospyros species for antiplasmodial properties.
Journal: Evidence-based complementary and alternative medicine : eCAM20080601
Title: Betulinic Acid for cancer treatment and prevention.
Journal: International journal of molecular sciences20080601
Title: Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.
Journal: Carbohydrate research20080505
Title: alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.
Journal: Journal of natural products20080501
Title: The use of primary hepatocytes from brown trout (Salmo trutta lacustris) and the fish cell lines RTH-149 and ZF-L for in vitro screening of (anti)estrogenic activity of wood extractives.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20080401
Title: Potential anti-tumor-promoting activity of 3alpha-hydroxy-D:A-friedooleanan-2-one from the stem bark of Mallotus philippensis.
Journal: Planta medica20080301
Title: Effects of the wood extractives dehydroabietic acid and betulinol on reproductive physiology of zebrafish (Danio rerio)-a two-generation study.
Journal: Aquatic toxicology (Amsterdam, Netherlands)20080218
Title: Tyrosinase inhibitors and sesquiterpene diglycosides from Guioa villosa.
Journal: Planta medica20080101
Title: An ethnobotanical study of medicinal plants in Mana Angetu district, southeastern Ethiopia.
Journal: Journal of ethnobiology and ethnomedicine20080101
Title: [Transformation of betulin diacetate by the Prins reaction].
Journal: Bioorganicheskaia khimiia20080101
Title: In vivo screening of antimalarial activity of Acacia mellifera (Benth) (Leguminosae) on Plasmodium berghei in mice.
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM20080101
Title: Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3beta-O-monodesmosidic saponins starting from betulin.
Journal: Bioorganic & medicinal chemistry20070915
Title: Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics20070801
Title: Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
Journal: Journal of natural products20070801
Title: Antimicrobial activity of oleanolic acid from Salvia officinalis and related compounds on vancomycin-resistant enterococci (VRE).
Journal: Biological & pharmaceutical bulletin20070601
Title: Selective inhibition of the interaction of C1q with immunoglobulins and the classical pathway of complement activation by steroids and triterpenoids sulfates.
Journal: Bioorganic & medicinal chemistry20070515
Title: In vitro evaluation of the cytotoxic and trypanocidal activities of Ampelozizyphus amazonicus (Rhamnaceae).
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20070501
Title: Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Journal: Journal of natural products20070401
Title: A new benzofuranone and anti-HIV constituents from the stems of Rhus chinensis.
Journal: Planta medica20070301
Title: Two new flavanone glycosides of Jasminum lanceolarium and their anti-oxidant activities.
Journal: Chemical & pharmaceutical bulletin20070301
Title: Simultaneous determination of betulin and betulinic acid in white birch bark using RP-HPLC.
Journal: Journal of pharmaceutical and biomedical analysis20070219
Title: Ethnobotanical remarks on Central and Southern Italy.
Journal: Journal of ethnobiology and ethnomedicine20070101
Title: Betulin binds to melanocortin receptors and antagonizes alpha-melanocyte stimulating hormone induced cAMP generation in mouse melanoma cells.
Journal: Cell biochemistry and function20070101
Title: Phytochemical and antinociceptive properties of Matayba elaeagnoides Radlk. barks.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20070101
Title: A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework.
Journal: Journal of ethnobiology and ethnomedicine20070101
Title: [Effect of nitrogen-containing derivatives of the plant triterpenes betulin and glycyrrhetic acid on the growth of MT-4, MOLT-4, CEM, and Hep G2 tumor cells].
Journal: Bioorganicheskaia khimiia20070101
Title: Physical, chemical and pharmacological characterization of a new oleogel-forming triterpene extract from the outer bark of birch (betulae cortex).
Journal: Planta medica20061201
Title: Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.
Journal: Bioorganic & medicinal chemistry20061001
Title: Boc-lysinated-betulonic acid: a potent, anti-prostate cancer agent.
Journal: Bioorganic & medicinal chemistry20060915
Title: Triterpenic and other lipophilic components from industrial cork byproducts.
Journal: Journal of agricultural and food chemistry20060906
Title: Pharmacological properties of the ubiquitous natural product betulin.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20060901
Title: Structure-activity relationships of triterpenoid saponins on fruiting body induction in Pleurotus ostreatus.
Journal: Bioscience, biotechnology, and biochemistry20060801
Title: Streblus asper Lour. (Shakhotaka): A Review of its Chemical, Pharmacological and Ethnomedicinal Properties.
Journal: Evidence-based complementary and alternative medicine : eCAM20060601
Title: Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2.
Journal: Bioorganic & medicinal chemistry20060301
Title: Protection of betulin against cadmium-induced apoptosis in hepatoma cells.
Journal: Toxicology20060301
Title: Acyl-CoA: cholesterol acyltransferase inhibitors from Ilex macropoda.
Journal: Archives of pharmacal research20060301
Title: Antiproliferative terpenoids from almond hulls (Prunus dulcis): identification and structure-activity relationships.
Journal: Journal of agricultural and food chemistry20060208
Title: [Treatment of actinic keratoses with birch bark extract: a pilot study].
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG20060201
Title: [Antimycobacterial activity of a dry birch bark extract on a model of experimental pulmonary tuberculosis].
Journal: Problemy tuberkuleza i boleznei legkikh20060101
Title: Chemical study of triterpenoid resinous materials in archaeological findings by means of direct exposure electron ionisation mass spectrometry and gas chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20060101
Title: A disease epidemic on Zizyphus mucronata in the Kruger National Park caused by Coniodictyum chevalieri.
Journal: Studies in mycology20060101
Title: Lupane-triterpenes from Bupleurum flavum.
Journal: Natural product research20051201
Title: Correlation of cytotoxic activity of betulinines and their hydroxy analogues.
Journal: Bioorganic & medicinal chemistry letters20051001
Title: Unusual naphthoquinones, catechin and triterpene from Byrsonima microphylla.
Journal: Phytochemistry20051001
Title: [Chemical constituents from the mangrove plant Ceriops tagal].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20051001
Title: Lupane triterpenoids from Maytenus species.
Journal: Journal of natural products20050701
Title: Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity.
Journal: Bioorganic & medicinal chemistry20050516
Title: Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.
Journal: Bioorganic & medicinal chemistry letters20050201
Title: Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.
Journal: Journal of natural products20050201
Title: Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.
Journal: Journal of natural products20050101
Title: [Synthesis and antitumor activity of cyclopropane derivatives of betulinic and betulonic acids].
Journal: Bioorganicheskaia khimiia20050101
Title: Protective effects of betulin and betulinic acid against ethanol-induced cytotoxicity in HepG2 cells.
Journal: Pharmacological reports : PR20050101
Title: [Interferon-inducing properties of dry birch bark extract and its effect on experimental infection caused by hepatitis C virus].
Journal: Voprosy virusologii20050101
Title: 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.
Journal: Bioorganic & medicinal chemistry letters20041206
Title: Effects of ursolic acid, betulin and sulfur-containing compounds on mucin release from airway goblet cells.
Journal: Planta medica20041201
Title: Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
Journal: Planta medica20041201
Title: The synergistic effects of betulin with acyclovir against herpes simplex viruses.
Journal: Antiviral research20041101
Title: Antibacterial activity of naphthoquinones and triterpenoids from Euclea natalensis root bark.
Journal: Journal of natural products20041101
Title: Furanolabdane diterpenes from Hypoestes purpurea.
Journal: Journal of natural products20041101
Title: In vitro androgenicity in pulp and paper mill effluents.
Journal: Environmental toxicology20041001
Title: Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line.
Journal: European journal of pharmacology20040913
Title: Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia.
Journal: Journal of natural products20040701
Title: Antitubercular constituents of Valeriana laxiflora.
Journal: Planta medica20040601
Title: Effects of the wood extractive betulinol and 17beta-oestradiol on reproduction in zebrafish, Danio rerio (Hamilton)--complications due to a bacterial infection.
Journal: Journal of fish diseases20040501
Title: Cytotoxic lupane-type triterpenoids from Acacia mellifera.
Journal: Phytochemistry20040401
Title: Four new triterpenoids from Maytenus ilicifolia.
Journal: Journal of natural products20040301
Title: Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.
Journal: Bioorganic & medicinal chemistry20040102
Title: New prenylated isoflavanones and other constituents of Lespedeza bicolor.
Journal: Fitoterapia20040101
Title: Prolyl endopeptidase inhibitors from Syzygium samarangense (Blume) Merr. & L. M. Perry.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20040101
Title: Determination of betulin in Grewia tiliaefolia by HPTLC.
Journal: Journal of separation science20040101
Title: New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships.
Journal: Journal of medicinal chemistry20031204
Title: Triterpenoids from the stembark of Pyrus communis.
Journal: Natural product research20031201
Title: Antimicrobial activity and constituents of Coccoloba acrostichoides.
Journal: Fitoterapia20031201
Title: Antitumor-promoting constituents from Chaenomeles sinensis KOEHNE and their activities in JB6 mouse epidermal cells.
Journal: Chemical & pharmaceutical bulletin20031101
Title: Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.
Journal: Fitoterapia20030701
Title: New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
Journal: Journal of natural products20030301
Title: Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
Journal: Journal of natural products20030201
Title: Cytotoxic triterpenes from the twigs of Celtis philippinensis.
Journal: Phytochemistry20030101
Title: New triterpenoids from Gentiana lutea.
Journal: Chemical & pharmaceutical bulletin20030101
Title: Differential effect of betulin and betulinic acid on cytokine production in human whole blood cell cultures.
Journal: Polish journal of pharmacology20030101
Title: Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Journal: Clinica chimica acta; international journal of clinical chemistry20021101
Title: Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
Journal: Journal of natural products20021101
Title: Synthesis of betulin derivatives and their protective effects against the cytotoxicity of cadmium.
Journal: Bioorganic & medicinal chemistry20021001
Title: Pentacyclic triterpenoids from Ilex macropoda.
Journal: Archives of pharmacal research20021001
Title: [Study on chemical constituents of rhizome of Anemone raddeana].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20020901
Title: Diterpenoids from the stem bark of Croton zambesicus.
Journal: Phytochemistry20020601
Title: Preparation of a 24-nor-1,4-dien-3-one triterpene derivative from betulin: a new route to 24-nortriterpene analogues.
Journal: The Journal of organic chemistry20020503
Title: Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.
Journal: Journal of natural products20020501
Title: Relationships between molecular properties and antimycobacterial activities of steroids.
Journal: Natural product letters20020401
Title: Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products.
Journal: Journal of natural products20020301
Title: [Synthesis and pharmacological activity of betulin dinicotinate].
Journal: Bioorganicheskaia khimiia20020101
Title: Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity.
Journal: Journal of natural products20011201
Title: Ethnopharmacology and bioinformatic combination for leads discovery: application to phospholipase A(2) inhibitors.
Journal: Phytochemistry20011101
Title: Antimycobacterial plant terpenoids.
Journal: Planta medica20011101
Title: Chemical characterization of fine particle emissions from fireplace combustion of woods grown in the northeastern United States.
Journal: Environmental science & technology20010701
Title: Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase.
Journal: Lipids20010501
Title: Constituents of Asteracantha longifolia.
Journal: Fitoterapia20010201
Title: 3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents.
Journal: Bioorganic & medicinal chemistry letters20010122
Title: Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.
Journal: Journal of medicinal chemistry19981105
Title: Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives.
Journal: Bioorganic & medicinal chemistry letters19980519
Title: Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
Journal: Journal of natural products19940201
Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Journal: Journal of natural products19910101
Title: Screening for new compounds with antiherpes activity.
Journal: Antiviral research19841001
Title: Król SK, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189.
Title: Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14(4):1639-51.
Title: Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111.
