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36304-84-4,MFCD01714607
Catalog No.:AA0039H5

36304-84-4 | Dimemorfan phosphate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
98%
in stock  
$104.00   $73.00
- +
100mg
98%
in stock  
$207.00   $145.00
- +
500mg
98%
in stock  
$734.00   $514.00
- +
1g
98%
in stock  
$1,274.00   $892.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0039H5
Chemical Name:
Dimemorfan phosphate
CAS Number:
36304-84-4
Molecular Formula:
C18H28NO4P
Molecular Weight:
353.3930
MDL Number:
MFCD01714607
SMILES:
OP(=O)(O)O.Cc1ccc2c(c1)[C@]13CCCC[C@@H]3[C@@H](C2)N(CC1)C
Properties
Computed Properties
 
Complexity:
401  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  

Literature

Title: A new method for quantitative determination of dimemorfan in human plasma using monolithic silica solid-phase extraction tips.

Journal: Legal medicine (Tokyo, Japan) 20120901

Title: The oxidative metabolism of dimemorfan by human cytochrome P450 enzymes.

Journal: Journal of pharmaceutical sciences 20100201

Title: Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice.

Journal: British journal of pharmacology 20080701

Title: Concise synthesis of dimemorfan (DF) starting from 3-hydroxymorphinan (3-HM).

Journal: Chemical & pharmaceutical bulletin 20080701

Title: Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.

Journal: Journal of neurochemistry 20080101

Title: [Otorhinolaringologyc approach of the chronic cough. Clinical case].

Journal: Anales otorrinolaringologicos ibero-americanos 20070101

Title: Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes.

Journal: Life sciences 20050701

Title: The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan.

Journal: British journal of pharmacology 20050401

Title: Dimemorfan enhances acetylcholine release from rat hippocampal slices.

Journal: Brain research 20040515

Title: Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice.

Journal: Behavioural brain research 20040505

Title: Anti-amnesic effect of dimemorfan in mice.

Journal: British journal of pharmacology 20030301

Title: Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan.

Journal: Brain research 19990313

Title: The nonnarcotic antitussive drug dimemorfan: a review.

Journal: Clinical therapeutics 19970101

Title: Effect of the centrally acting antitussives on ascites tumor cells.

Journal: Japanese journal of pharmacology 19830401

Title: Shin EJ, et al. Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice. Behav Brain Res. 2004 May 5;151(1-2):267-76.

Title: Wang YH, et al. Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. Br J Pharmacol. 2008 Jul;154(6):1327-38.

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