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171228-49-2,MFCD28138428
Catalog No.:AA0039I3

171228-49-2 | Posaconazole

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10mg
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$7.00   $5.00
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50mg
98%
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$9.00   $7.00
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1g
98%
in stock  
$39.00   $28.00
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5g
98%
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$142.00   $100.00
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10g
98%
in stock  
$245.00   $171.00
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25g
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$485.00   $340.00
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0039I3
Chemical Name:
Posaconazole
CAS Number:
171228-49-2
Molecular Formula:
C37H42F2N8O4
Molecular Weight:
700.7774
MDL Number:
MFCD28138428
SMILES:
CC[C@H](n1ncn(c1=O)c1ccc(cc1)N1CCN(CC1)c1ccc(cc1)OC[C@@H]1CO[C@@](C1)(Cn1cncn1)c1ccc(cc1F)F)[C@@H](O)C
Properties
Computed Properties
 
Complexity:
1170  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
51  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
12  
XLogP3:
4.6  

Downstream Synthesis Route
69171-62-6    171228-49-2   
4-(<i>tert</i>-butyl-dimethyl-silanyloxy)-butyricacid2-{4-4-(4-{4-5-(2,4-difluoro-phenyl)-5-1,2,4triazol-1-ylmethyl-tetrahydro-furan-3-ylmethoxy-phenyl}-piperazin-1-yl)-phenyl-5-oxo-4,5-dihydro-1,2,4triazol-1-yl}-1-methyl-butylester 

[1]TetrahedronLetters,2001,vol.42,p.7141-7143

[1]TetrahedronLetters,2001,vol.42,p.7141-7143

[2]Patent:EP1027349,2005,B1.Locationinpatent:Page11

[1]Patent:WO2017/51342,2017,A1.Locationinpatent:Page/Pagecolumn19;20

[2]Patent:CN106366076,2017,A.Locationinpatent:Paragraph0020;0044;0045;0049;0050;0054;0055

[3]TetrahedronLetters,2004,vol.45,p.8249-8251

[4]Patent:CN105622591,2016,A.Locationinpatent:Paragraph0021

[5]Patent:CN109970725,2019,A.Locationinpatent:Paragraph0045-0099

[6]Patent:US2014/343285,2014,A1.Locationinpatent:Paragraph0344

[7]Patent:CN106749207,2017,A.Locationinpatent:Paragraph0038;0039;0040

[8]Patent:CN109796446,2019,A.Locationinpatent:Paragraph0043;0069;0070;0071;0097

[9]TetrahedronLetters,2002,vol.43,p.3359-3363

[10]Patent:WO2009/141837,2009,A2.Locationinpatent:Page/Pagecolumn23

[11]Patent:WO2011/158248,2011,A2.Locationinpatent:Page/Pagecolumn30-31

[12]Patent:WO2015/59716,2015,A2.Locationinpatent:Page/Pagecolumn26;27

[13]RSCAdvances,2016,vol.6,p.58088-58098

[14]Patent:US2019/71408,2019,A1.Locationinpatent:Paragraph0250

[15]Patent:WO2019/77627,2019,A1.Locationinpatent:Page/Pagecolumn14;35;36

[1]BioorganicandMedicinalChemistryLetters,2006,vol.16,p.186-190

[1]BioorganicandMedicinalChemistryLetters,2006,vol.16,p.186-190

Literature

Title: Azole resistance in canine and feline isolates of Aspergillus fumigatus.

Journal: Comparative immunology, microbiology and infectious diseases 20151001

Title: Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1.

Journal: Antimicrobial agents and chemotherapy 20140801

Title: Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011.

Journal: Antimicrobial agents and chemotherapy 20140301

Title: A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: Epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole for six Candida species as determined by the colorimetric Sensititre YeastOne method.

Journal: Journal of clinical microbiology 20130801

Title: In vitro antifungal susceptibility of clinically relevant species belonging to Aspergillus section Flavi.

Journal: Antimicrobial agents and chemotherapy 20130401

Title: Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans.

Journal: PloS one 20130101

Title: A new solid oral tablet formulation of posaconazole: a randomized clinical trial to investigate rising single- and multiple-dose pharmacokinetics and safety in healthy volunteers.

Journal: The Journal of antimicrobial chemotherapy 20121101

Title: In vitro-in vivo correlation of voriconazole resistance due to G448S mutation (cyp51A gene) in Aspergillus fumigatus.

Journal: Diagnostic microbiology and infectious disease 20121101

Title: Experimental murine model of disseminated infection by Saksenaea vasiformis: successful treatment with posaconazole.

Journal: Medical mycology 20121001

Title: Zygomycosis over-infection during voriconazole therapy for aspergillosis in a heart transplant patient, successfully treated with liposomal amphotericin and posaconazole.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20121001

Title: Are epidemiologic cut-off values predictors of the in vivo efficacy of azoles in experimental aspergillosis?

Journal: Diagnostic microbiology and infectious disease 20121001

Title: Meningitis due to Cryptococcus neoformans: treatment with posaconazole.

Journal: Current HIV research 20121001

Title: Case report of hepatic mucormycosis after liver transplantation: successful treatment with liposomal amphotericin B followed by posaconazole sequential therapy.

Journal: Transplantation proceedings 20121001

Title: Reversible skeletal disease and high fluoride serum levels in hematologic patients receiving voriconazole.

Journal: Blood 20120920

Title: Successful treatment of cutaneous zygomycosis with extensive surgical debridement and oral posaconazole in an immunocompetent patient.

Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20120901

Title: Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901

Title: Invasive fungal breakthrough infections, fungal colonization and emergence of resistant strains in high-risk patients receiving antifungal prophylaxis with posaconazole: real-life data from a single-centre institutional retrospective observational study.

Journal: The Journal of antimicrobial chemotherapy 20120901

Title: Pleurostomophora ochracea, a novel agent of human eumycetoma with yellow grains.

Journal: Journal of clinical microbiology 20120901

Title: Poor absorption of high-dose posaconazole in pediatric bone marrow transplant patients.

Journal: The Annals of pharmacotherapy 20120901

Title: Emergence of Aspergillus calidoustus infection in the era of posttransplantation azole prophylaxis.

Journal: Transplantation 20120827

Title: Comparison of posaconazole versus weekly amphotericin B lipid complex for the prevention of invasive fungal infections in hematopoietic stem-cell transplantation.

Journal: Transplantation 20120815

Title: In vitro antifungal susceptibility of filamentous fungi causing rare infections: synergy testing of amphotericin B, posaconazole and anidulafungin in pairs.

Journal: The Journal of antimicrobial chemotherapy 20120801

Title: High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis.

Journal: The Journal of antimicrobial chemotherapy 20120801

Title: Characterization of an unusual ring-contraction degradant of the antifungal agent posaconazole.

Journal: Magnetic resonance in chemistry : MRC 20120801

Title: Success of posaconazole therapy in a heart transplanted patient with Alternaria infectoria cutaneous infection.

Journal: Medical mycology 20120701

Title: Efficacy of posaconazole in a murine model of disseminated infection caused by Apophysomyces variabilis.

Journal: The Journal of antimicrobial chemotherapy 20120701

Title: Structural characterization of a novel degradant of the antifungal agent posaconazole.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: EUCAST technical note on Aspergillus and amphotericin B, itraconazole, and posaconazole.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120701

Title: Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi.

Journal: International journal of antimicrobial agents 20120701

Title: The management of febrile neutropenia in the posaconazole era: a new challenge?

Journal: Haematologica 20120701

Title: Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome.

Journal: European journal of clinical pharmacology 20120601

Title: A murine model of Cryptococcus gattii meningoencephalitis.

Journal: The Journal of antimicrobial chemotherapy 20120601

Title: Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies.

Journal: International journal of antimicrobial agents 20120601

Title: Posaconazole treatment in hematology patients: a pilot study of therapeutic drug monitoring.

Journal: Therapeutic drug monitoring 20120601

Title: Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease.

Journal: Journal of medicinal chemistry 20120510

Title: In vitro activity of Amphotericin B against zygomycetes isolated from deep mycoses: a comparative study between incubation in aerobic and hyperbaric atmosphere.

Journal: Medical mycology 20120501

Title: Voriconazole and posaconazole improve asthma severity in allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitization.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20120501

Title: Posaconazole prophylaxis during front-line chemotherapy of acute myeloid leukemia: a single-center, real-life experience.

Journal: Haematologica 20120401

Title: Impact of benzodiazepines on posaconazole serum concentrations. A population-based pharmacokinetic study on drug interaction.

Journal: Current medical research and opinion 20120401

Title: In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions.

Journal: Veterinary microbiology 20120323

Title: Successful treatment of disseminated mixed invasive fungal infection after hematopoietic stem cell transplantation for severe aplastic anemia.

Journal: Pediatric transplantation 20120301

Title: Candida kefyr fungal enteritis following autologous BMT.

Journal: Bone marrow transplantation 20120301

Title: Posaconazole: when and how? The clinician's view.

Journal: Mycoses 20120301

Title: Comparative clinical effectiveness of prophylactic voriconazole/posaconazole to fluconazole/itraconazole in patients with acute myeloid leukemia/myelodysplastic syndrome undergoing cytotoxic chemotherapy over a 12-year period.

Journal: Haematologica 20120301

Title: New species of Madurella, causative agents of black-grain mycetoma.

Journal: Journal of clinical microbiology 20120301

Title: Effect of pH on in vitro susceptibility of Candida glabrata and Candida albicans to 11 antifungal agents and implications for clinical use.

Journal: Antimicrobial agents and chemotherapy 20120301

Title: Rapid and sensitive determination of posaconazole in patient plasma by capillary electrophoresis with field-amplified sample stacking.

Journal: Journal of chromatography. A 20120224

Title: Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120201

Title: Disseminated sporotrichosis in a patient with hairy cell leukemia treated with amphotericin B and posaconazole.

Journal: Medical mycology 20120201

Title: Long-term treatment of invasive sinus, tracheobroncheal, pulmonary and intracerebral aspergillosis in acute lymphoblastic leukaemia.

Journal: Infection 20120201

Title: A randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded study of four treatment regimens of posaconazole in adults with toenail onychomycosis.

Journal: The British journal of dermatology 20120201

Title: Posaconazole: the case for therapeutic drug monitoring.

Journal: Therapeutic drug monitoring 20120201

Title: Combination therapy for mucormycosis: why, what, and how?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120201

Title: Posaconazole serum level on day 2 predicts steady state posaconazole serum level.

Journal: Therapeutic drug monitoring 20120201

Title: A multicenter, open-label study of posaconazole oral suspension in the treatment of invasive fungal infections in patients refractory to or intolerant of first-line therapy.

Journal: Future microbiology 20120201

Title: In vitro activities of new triazole antifungal agents, posaconazole and voriconazole, against oral Candida isolates from patients suffering from denture stomatitis.

Journal: Mycopathologia 20120101

Title: Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, Japan.

Journal: Antimicrobial agents and chemotherapy 20120101

Title: Antifungal treatment affects the laboratory diagnosis of invasive aspergillosis.

Journal: Journal of clinical pathology 20120101

Title: Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers.

Journal: Expert opinion on drug metabolism & toxicology 20120101

Title: [53-year-old woman with life-threatening complications after use of ciprofloxacin and posaconazol].

Journal: Deutsche medizinische Wochenschrift (1946) 20120101

Title: Oral antifungal therapy for Fusarium-associated chronic rhinosinusitis.

Journal: International forum of allergy & rhinology 20120101

Title: Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in Spain.

Journal: BMC infectious diseases 20120101

Title: Cutaneous zygomycosis.

Journal: Clinics in dermatology 20120101

Title: [Azole resistance in Aspergillus fumigatus in the Netherlands--increase due to environmental fungicides?].

Journal: Nederlands tijdschrift voor geneeskunde 20120101

Title: Paecilomyces lilacinus and alternaria infectoria cutaneous infections in a sarcoidosis patient after double-lung transplantation.

Journal: Acta clinica Belgica 20120101

Title: Advances in systemic antifungal therapy.

Journal: Clinics in dermatology 20120101

Title: Triazole antifungal agents in invasive fungal infections: a comparative review.

Journal: Drugs 20111224

Title: Structural determination of an unknown degradation product in posaconazole drug product using CASI technology in a Fourier transform ion cyclotron resonance mass spectrometer.

Journal: Rapid communications in mass spectrometry : RCM 20111215

Title: Pneumothorax and empyema complicating Scedosporium apiospermum mycetoma: not just a problem in the immunocompromised patients.

Journal: Irish journal of medical science 20111201

Title: Posaconazole for the treatment of mucormycosis.

Journal: International journal of antimicrobial agents 20111201

Title: In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing.

Journal: Diagnostic microbiology and infectious disease 20111201

Title: Posaconazole for chronic refractory coccidioidal meningitis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111201

Title: Treatment of refractory coccidioidomycosis with voriconazole or posaconazole.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111201

Title: Measurement of posaconazole, itraconazole, and hydroxyitraconazole in plasma/serum by high-performance liquid chromatography with fluorescence detection.

Journal: Therapeutic drug monitoring 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: [Antifungal therapy update: new drugs and medical uses].

Journal: Enfermedades infecciosas y microbiologia clinica 20111201

Title: Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review.

Journal: Tropical biomedicine 20111201

Title: [In vitro synergisms among hydrazones, ajoeno and posaconazole against Cryptococcus spp].

Journal: Investigacion clinica 20111201

Title: A dried blood spots technique based LC-MS/MS method for the analysis of posaconazole in human whole blood samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: Posaconazole versus fluconazole or itraconazole for prevention of invasive fungal infections in patients undergoing intensive cytotoxic therapy for acute myeloid leukemia or myelodysplasia: a cost effectiveness analysis.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111101

Title: A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20111101

Title: Microdilution in vitro antifungal susceptibility of Exophiala dermatitidis, a systemic opportunist.

Journal: Medical mycology 20111101

Title: Optimising absorption of posaconazole.

Journal: Mycoses 20111101

Title: Triazole and echinocandin MIC distributions with epidemiological cutoff values for differentiation of wild-type strains from non-wild-type strains of six uncommon species of Candida.

Journal: Journal of clinical microbiology 20111101

Title: Wild-type MIC distributions and epidemiologic cutoff values for fluconazole, posaconazole, and voriconazole when testing Cryptococcus neoformans as determined by the CLSI broth microdilution method.

Journal: Diagnostic microbiology and infectious disease 20111101

Title: EUCAST technical note on posaconazole.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20111101

Title: Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations.

Journal: Clinical pharmacokinetics 20111101

Title: A common fungus, an unusual (and deadly) infection.

Journal: The American journal of medicine 20111101

Title: T. asahii pulmonary infection as a complication of TNF-inhibitor and steroids: posaconazole pharmacotherapy and risk analysis.

Journal: Journal of the Mississippi State Medical Association 20111101

Title: [Exophytic and ulcerative lesions on the lower limb in a Moroccan patient].

Journal: Medicina clinica 20111015

Title: Risk factors for invasive aspergillosis in acute myeloid leukemia patients prophylactically treated with posaconazole.

Journal: Medical mycology 20111001

Title: In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method.

Journal: Diagnostic microbiology and infectious disease 20111001

Title: Update in treatment of Chagas disease.

Journal: Current opinion in infectious diseases 20111001

Title: Breakthrough fungemia due to Candida glabrata during posaconazole prophylaxis in hematology patients treated with anidulafungin - report of 5 cases.

Journal: Journal of chemotherapy (Florence, Italy) 20111001

Title: In vitro susceptibility of filamentous fungi to itraconazole, voriconazole and posaconazole by Clinical and Laboratory Standards Institute reference method and E-test.

Journal: Mycoses 20110901

Title: Antifungal activity of posaconazole and granulocyte colony-stimulating factor in the treatment of disseminated zygomycosis (mucormycosis) in a neutropaenic murine model.

Journal: Mycoses 20110901

Title: Posaconazole: a new antifungal weapon.

Journal: Reviews on recent clinical trials 20110901

Title: Peripheral neuropathy in patients on long-term triazole antifungal therapy.

Journal: The Journal of antimicrobial chemotherapy 20110901

Title: A twice daily posaconazole dosing algorithm for children with chronic granulomatous disease.

Journal: The Pediatric infectious disease journal 20110901

Title: Rhino-orbital-cerebral mucormycosis (ROCM): a comprehensive case review.

Journal: Aviation, space, and environmental medicine 20110901

Title: 74-year-old man from the pacific northwest with fever and a lung mass.

Journal: Chest 20110901

Title: Disseminated nocardiosis masking an atypical zygomycosis presentation in a kidney transplant recipient.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20110801

Title: Endophthalmitis as primary clinical manifestation of fatal fusariosis in an allogeneic stem cell recipient.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20110801

Title: Fatal disseminated infection due to Scedosporium prolificans in a patient with acute myeloid leukemia and posaconazole prophylaxis.

Journal: Leukemia & lymphoma 20110801

Title: Posaconazole plasma concentrations in critically ill patients.

Journal: Therapeutic drug monitoring 20110801

Title: Madurella mycetomatis mycetoma treated successfully with oral posaconazole.

Journal: Journal of chemotherapy (Florence, Italy) 20110801

Title: Posaconazole prophylaxis during induction therapy of patients with acute lymphoblastic leukaemia.

Journal: Mycoses 20110701

Title: Cavitary lung lesions in a renal transplant recipient.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110701

Title: Synthesis and in vitro antimicrobial activities of new (cyano-NNO-azoxy)pyrazole derivatives.

Journal: Bioorganic & medicinal chemistry letters 20110601

Title: Selection of resistant fungi in liver transplant recipients during use of newer antifungal agents -- a report of two cases.

Journal: Annals of the Academy of Medicine, Singapore 20110601

Title: European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update.

Journal: Bone marrow transplantation 20110501

Title: Clinical efficacy and safety of primary antifungal prophylaxis with posaconazole vs itraconazole in allogeneic blood and marrow transplantation.

Journal: Bone marrow transplantation 20110501

Title: Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapy.

Journal: The Journal of infectious diseases 20110501

Title: Cerebral mucormycosis in a diabetic man.

Journal: Connecticut medicine 20110501

Title: Efficacy, safety, and breakthrough infections associated with standard long-term posaconazole antifungal prophylaxis in allogeneic stem cell transplantation recipients.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110401

Title: Aspergillus endocarditis 2003-2009.

Journal: Medical mycology 20110401

Title: Retrospective survey on the off-label use of posaconazole in pediatric hematology patients.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110401

Title: Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.

Journal: Antimicrobial agents and chemotherapy 20110401

Title: Delayed recalcitrant fungal endophthalmitis secondary to Curvularia.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20110401

Title: Therapeutic efficacy of posaconazole against Candida glabrata in a murine model of vaginitis.

Journal: Mycoses 20110301

Title: Combined therapy against murine-disseminated infection by Fusarium verticillioides.

Journal: Mycopathologia 20110301

Title: Posaconazole susceptibility of clinical yeast isolates determined by an agar diffusion and microdilution method.

Journal: International journal of antimicrobial agents 20110301

Title: A post-marketing evaluation of posaconazole plasma concentrations in neutropenic patients with haematological malignancy receiving posaconazole prophylaxis.

Journal: International journal of antimicrobial agents 20110301

Title: Lack of evidence for exposure-response relationship in the use of posaconazole as prophylaxis against invasive fungal infections.

Journal: Clinical pharmacology and therapeutics 20110301

Title: Posaconazole: a pharmacoeconomic review of its use in the prophylaxis of invasive fungal disease in immunocompromised hosts.

Journal: PharmacoEconomics 20110301

Title: Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies.

Journal: The Journal of antimicrobial chemotherapy 20110201

Title: Therapeutic drug monitoring of voriconazole and posaconazole.

Journal: Pharmacotherapy 20110201

Title: Lack of pharmacokinetic drug interaction between oral posaconazole and caspofungin or micafungin.

Journal: Journal of clinical pharmacology 20110101

Title: Two new species of Mucor from clinical samples.

Journal: Medical mycology 20110101

Title: Posaconazole cerebrospinal concentrations in an HIV-infected patient with brain mucormycosis.

Journal: The Journal of antimicrobial chemotherapy 20110101

Title: Posaconazole prophylaxis in patients with acute myelogenous leukaemia--results from an observational study.

Journal: Mycoses 20110101

Title: Clinical experience with posaconazole prophylaxis--a retrospective analysis in a haematological unit.

Journal: Mycoses 20110101

Title: Posaconazole: clinical pharmacokinetics and drug interactions.

Journal: Mycoses 20110101

Title: Caspofungin plus posaconazole as salvage therapy of invasive fungal infections in immunocompromised patients.

Journal: Mycoses 20110101

Title: Posaconazole as part of the antifungal armamentarium in the intensive care unit--case reports from a surgical ICU.

Journal: Mycoses 20110101

Title: Cost effectiveness of posaconazole in the prophylaxis of invasive fungal infections in acute leukaemia patients for the French healthcare system.

Journal: Journal of medical economics 20110101

Title: Successful treatment of chronic mucocutaneous candidiasis caused by azole-resistant Candida albicans with posaconazole.

Journal: Clinical & developmental immunology 20110101

Title: Pharmacology and metabolism of voriconazole and Posaconazole in the treatment of invasive aspergillosis: review of the literature.

Journal: European journal of medical research 20110101

Title: Prophylaxis and treatment of invasive aspergillosis with voriconazole, posaconazole and caspofungin: review of the literature.

Journal: European journal of medical research 20110101

Title: Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.

Journal: PloS one 20110101

Title: Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51).

Journal: Advances in parasitology 20110101

Title: Long-term treatment of refractory invasive fungal infection with posaconazole: additive value of therapeutic drug monitoring.

Journal: Acta clinica Belgica 20110101

Title: [Cost effectiveness of posaconazole versus fluconazole/itraconazole in the prophylactic treatment of invasive fungal infections in Mexico].

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101

Title: Posaconazole for chronic pulmonary aspergillosis: the next strategy against the threat of azole-resistant Aspergillus infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101215

Title: Efficacy and safety of posaconazole for chronic pulmonary aspergillosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101215

Title: Use of posaconazole in the treatment of infective rhinocerebral mucormycosis.

Journal: The Journal of laryngology and otology 20101201

Title: Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry.

Journal: Clinical chemistry and laboratory medicine 20101201

Title: In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspofungin.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Ultra-performance liquid chromatography mass spectrometry and sensitive bioassay methods for quantification of posaconazole plasma concentrations after oral dosing.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Molecular phylogeny and proposal of two new species of the emerging pathogenic fungus Saksenaea.

Journal: Journal of clinical microbiology 20101201

Title: Sixty-year-old man with slowly expanding nodular plaque on the thigh.

Journal: Journal of the American Academy of Dermatology 20101201

Title: Managing invasive fungal disease in immunocompromised patients.

Journal: Future microbiology 20101201

Title: Successful treatment of cutaneous zygomycosis with intravenous amphotericin B followed by oral posaconazole in a multivisceral transplant recipient.

Journal: Transplantation 20101127

Title: AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus.

Journal: International journal of medical microbiology : IJMM 20101101

Title: Isavuconazole: a comprehensive review of spectrum of activity of a new triazole.

Journal: Mycopathologia 20101101

Title: Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.

Journal: Antimicrobial agents and chemotherapy 20101101

Title: In vitro and in vivo antifungal susceptibilities of the Mucoralean fungus Cunninghamella.

Journal: Antimicrobial agents and chemotherapy 20101101

Title: Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain.

Journal: Antimicrobial agents and chemotherapy 20101101

Title: Antifungal therapy in a murine model of disseminated infection by Cryptococcus gattii.

Journal: Antimicrobial agents and chemotherapy 20101001

Title: Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.

Journal: Antimicrobial agents and chemotherapy 20101001

Title: In vitro and in vivo activities of posaconazole against zygomycetes with various degrees of susceptibility.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Effect of posaconazole on the pharmacokinetics of fosamprenavir and vice versa in healthy volunteers.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Comparative survival and cost of antifungal therapy: posaconazole versus standard antifungals in the treatment of refractory invasive aspergillosis.

Journal: Current medical research and opinion 20101001

Title: Clinical pharmacodynamics and pharmacokinetics of the antifungal extended-spectrum triazole posaconazole: an overview.

Journal: British journal of clinical pharmacology 20101001

Title: In vitro susceptibility testing of Aspergillus spp. against voriconazole, itraconazole, posaconazole, amphotericin B and caspofungin.

Journal: Chinese medical journal 20101001

Title: A noninvasive renal fungus ball caused by Rhizopus--a previously unreported manifestation of zygomycosis.

Journal: Medical mycology 20100901

Title: Economic evaluation of posaconazole versus fluconazole prophylaxis in patients with graft-versus-host disease (GVHD) in the Netherlands.

Journal: Annals of hematology 20100901

Title: Steady-state intrapulmonary pharmacokinetics and pharmacodynamics of posaconazole in lung transplant recipients.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Experimental murine scedosporiosis: histopathology and azole treatment.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: In vitro antifungal activities of isavuconazole and comparators against rare yeast pathogens.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Wild-type MIC distributions and epidemiological cutoff values for the triazoles and six Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document).

Journal: Journal of clinical microbiology 20100901

Title: Antifungal activity of posaconazole against Candida spp. and non-Candida clinical yeasts isolates.

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20100901

Title: Ulcerated plaque under a ruby ring in an immunosuppressed patient.

Journal: Dermatology online journal 20100815

Title: Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi.

Journal: The Journal of biological chemistry 20100813

Title: Cunninghamella bertholletiae exhibits increased resistance to human neutrophils with or without antifungal agents as compared to Rhizopus spp.

Journal: Medical mycology 20100801

Title: Posaconazole salvage treatment in paediatric patients: a multicentre survey.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100801

Title: Development, validation, and routine application of a high-performance liquid chromatography method coupled with a single mass detector for quantification of itraconazole, voriconazole, and posaconazole in human plasma.

Journal: Antimicrobial agents and chemotherapy 20100801

Title: Clinical effectiveness of posaconazole prophylaxis in patients with acute myelogenous leukaemia (AML): a 6 year experience of the Cologne AML cohort.

Journal: The Journal of antimicrobial chemotherapy 20100701

Title: Antifungal susceptibility profile of human-pathogenic species of Lichtheimia.

Journal: Antimicrobial agents and chemotherapy 20100701

Title: A comparative study of posaconazole and benznidazole in the prevention of heart damage and promotion of trypanocidal immune response in a murine model of Chagas disease.

Journal: International journal of antimicrobial agents 20100701

Title: Intracellular concentrations of posaconazole in different compartments of peripheral blood.

Journal: Antimicrobial agents and chemotherapy 20100701

Title: Antifungal therapies in murine disseminated phaeohyphomycoses caused by Exophiala species.

Journal: The Journal of antimicrobial chemotherapy 20100701

Title: Exposure-response of posaconazole used for prophylaxis against invasive fungal infections: evaluating the need to adjust doses based on drug concentrations in plasma.

Journal: Clinical pharmacology and therapeutics 20100701

Title: Chagas disease: pushing through the pipeline.

Journal: Nature 20100624

Title: Conazoles.

Journal: Molecules (Basel, Switzerland) 20100609

Title: Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601

Title: Emerging therapeutic options in fulminant invasive rhinocerebral mucormycosis.

Journal: Auris, nasus, larynx 20100601

Title: Breakthrough zygomycosis on posaconazole prophylaxis after allogeneic stem cell transplantation.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100601

Title: Disseminated Rhizopus microsporus infection cured by salvage allogeneic hematopoietic stem cell transplantation, antifungal combination therapy, and surgical resection.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100601

Title: Potential synergistic activity of antimycotic substances in combination with human platelets against Aspergillus fumigatus.

Journal: The Journal of antimicrobial chemotherapy 20100601

Title: Pharmacokinetic/pharmacodynamic profile of posaconazole.

Journal: Clinical pharmacokinetics 20100601

Title: Rhizopus oryzae skin infection treated with posaconazole in a boy with chronic granulomatous disease.

Journal: The Pediatric infectious disease journal 20100601

Title: Mucormycosis may mimic disease relapse in Wegener's granulomatosis.

Journal: The Journal of rheumatology 20100601

Title: [Economic evaluation of posaconazole in prophylaxis of invasive fungal infections in Italian neutropenic patients with acute myeloid leukaemia or myelodysplastic syndrome].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20100601

Title: Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery.

Journal: Journal of medicinal chemistry 20100527

Title: Antifungal activity of amphotericin B, caspofungin and posaconazole on Candida albicans biofilms in intermediate and mature development phases.

Journal: Mycoses 20100501

Title: Economic evaluation of posaconazole vs fluconazole in the prevention of invasive fungal infections in patients with GVHD following haematopoietic SCT.

Journal: Bone marrow transplantation 20100501

Title: Correlation between in vitro activity of posaconazole and in vivo efficacy against Rhizopus oryzae infection in mice.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Cutaneous model of invasive aspergillosis.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Use of a high-resolution melt assay to characterize codon 54 of the cyp51A gene of Aspergillus fumigatus on a Rotor-Gene 6000 instrument.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Skin concentrations and pharmacokinetics of posaconazole after oral administration.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Severe life threatening neurotoxicity in a child with acute lymphoblastic leukemia receiving posaconazole and vincristine.

Journal: Pediatric blood & cancer 20100501

Title: Pharmacoeconomic evaluation of voriconazole versus posaconazole for antifungal prophylaxis in acute myeloid leukaemia.

Journal: The Journal of antimicrobial chemotherapy 20100501

Title: Traditional and emerging antifungal therapies.

Journal: Proceedings of the American Thoracic Society 20100501

Title: [Prophylaxis use of posaconazole (P) in an hemato-oncology unit: a retrospective study].

Journal: Pathologie-biologie 20100401

Title: Unusual presentation of chromoblastomycosis due to Cladophialophora carrionii in a renal and pancreas transplant recipient patient successfully treated with posaconazole and surgical excision.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100401

Title: In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.

Journal: Antimicrobial agents and chemotherapy 20100401

Title: In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes.

Journal: The Journal of antimicrobial chemotherapy 20100401

Title: Successful treatment with posaconazole of a patient with chronic Chagas disease and systemic lupus erythematosus.

Journal: The American journal of tropical medicine and hygiene 20100401

Title: Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.

Journal: PLoS neglected tropical diseases 20100401

Title: Presumed Scopulariopsis brevicaulis chorioretinitis in a stem cell transplant recipient.

Journal: Clinical & experimental ophthalmology 20100401

Title: Rifampin and posaconazole coadministration leads to decreased serum posaconazole concentrations.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100315

Title: Onychomycosis.

Journal: Clinics in dermatology 20100304

Title: Successful treatment of pulmonary zygomycosis in two transplant recipients with liposomal amphotericin B and partial surgical resection followed by posaconazole.

Journal: Mycoses 20100301

Title: Splenic hyalohyphomycosis, molecularly and immunologically consistent with invasive aspergillosis, in a patient with acute lymphoblastic leukemia.

Journal: American journal of hematology 20100301

Title: Müeller-Hinton methylene blue media as an alternative to RPMI 1640 for determining the susceptibility of Cryptococcus neoformans and Cryptococcus gattii to posaconazole with Etest.

Journal: Mycoses 20100301

Title: Efficacy of posaconazole as treatment and prophylaxis against Fusarium solani.

Journal: Antimicrobial agents and chemotherapy 20100301

Title: Current controversies in treating invasive zygomycosis.

Journal: Journal of pediatric hematology/oncology 20100301

Title: Successful triple combination therapy of disseminated absidia corymbifera infection in an adolescent with osteosarcoma.

Journal: Journal of pediatric hematology/oncology 20100301

Title: Report of a successful treatment of pulmonary Cunninghamella bertholletiae infection with liposomal amphotericin and posaconazole in a child with GvHD and review of the literature.

Journal: Journal of pediatric hematology/oncology 20100301

Title: Sinonasal mucormycosis: case report.

Journal: European annals of otorhinolaryngology, head and neck diseases 20100301

Title: Drug costs and utilization after implementation of a posaconazole prophylaxis protocol in adults with acute myelogenous leukemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100215

Title: [Painful peripheral neuropathy associated with voriconazole during the treatment of chronic cavitary pulmonary aspergillosis].

Journal: La Revue de medecine interne 20100201

Title: Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.

Journal: Antimicrobial agents and chemotherapy 20100201

Title: In vitro activity of antifungal combinations against Candida albicans biofilms.

Journal: The Journal of antimicrobial chemotherapy 20100201

Title: Population pharmacokinetics of posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome.

Journal: Current medical research and opinion 20100201

Title: Evaluation of antifungal therapy in a neutropenic murine model of Neoscytalidium dimidiatum infection.

Journal: International journal of antimicrobial agents 20100201

Title: Murine model of a disseminated infection by the novel fungus Fonsecaea monophora and successful treatment with posaconazole.

Journal: Antimicrobial agents and chemotherapy 20100201

Title: Malignant thymoma with immunodeficiency (Good syndrome) associated with mucormycosis.

Journal: American journal of clinical oncology 20100201

Title: Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies.

Journal: Mycoses 20100101

Title: Iatrogenic eyelid granulomata.

Journal: American journal of therapeutics 20100101

Title: Efficacy of posaconazole in a murine disseminated infection by Candida tropicalis.

Journal: Antimicrobial agents and chemotherapy 20100101

Title: Factors influencing pharmacokinetics of prophylactic posaconazole in patients undergoing allogeneic stem cell transplantation.

Journal: Antimicrobial agents and chemotherapy 20100101

Title: Pharmacokinetics of a single dose of the antifungal posaconazole as oral suspension in subjects with hepatic impairment.

Journal: Current medical research and opinion 20100101

Title: Primary antifungal prophylaxis in acute myeloblastic leukemia and myelodysplastic syndrome--still an open question?

Journal: Leukemia & lymphoma 20100101

Title: Cost-effectiveness of posaconazole compared with standard azole therapy for prevention of invasive fungal infections in patients at high risk in Switzerland.

Journal: Oncology 20100101

Title: Intermittent posaconazole regimen to treat superficial Scytalidium dimidiatum infection.

Journal: European journal of dermatology : EJD 20100101

Title: Posaconazole.

Journal: Journal of postgraduate medicine 20100101

Title: Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections.

Journal: Drug design, development and therapy 20100101

Title: Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Therapeutic drug monitoring of posaconazole: a monocentric study with 54 adults.

Journal: Antimicrobial agents and chemotherapy 20091201

Title: Impact of antifungal prophylaxis on colonization and azole susceptibility of Candida species.

Journal: Antimicrobial agents and chemotherapy 20091201

Title: Correlation of in vitro activity, serum levels, and in vivo efficacy of posaconazole against Rhizopus microsporus in a murine disseminated infection.

Journal: Antimicrobial agents and chemotherapy 20091201

Title: Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens.

Journal: Journal of clinical microbiology 20091201

Title: Phospholipidosis in neurons caused by posaconazole, without evidence for functional neurologic effects.

Journal: Toxicologic pathology 20091201

Title: Isoquinoline-based analogs of the cancer drug clinical candidate tipifarnib as anti-Trypanosoma cruzi agents.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Successful treatment of ascending aortic graft and valve endocarditis after debulking splenectomy for invasive aspergillosis and mucor.

Journal: The American surgeon 20091201

Title: Use of posaconazole in the treatment of invasive fungal  infections.

Journal: Expert review of hematology 20091201

Title: Cutaneous zygomycosis caused by Saksenaea vasiformis following water-related wound in a 24-year-old immunocompetent woman.

Journal: Mycoses 20091101

Title: Comparison of assessment of oxygen consumption, Etest, and CLSI M38-A2 broth microdilution methods for evaluation of the susceptibility of Aspergillus fumigatus to posaconazole.

Journal: Antimicrobial agents and chemotherapy 20091101

Title: Effect of varying amounts of a liquid nutritional supplement on the pharmacokinetics of posaconazole in healthy volunteers.

Journal: Antimicrobial agents and chemotherapy 20091101

Title: Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation.

Journal: The Journal of antimicrobial chemotherapy 20091101

Title: [Non-fatal disseminated mucormycosis in a solid organ transplant].

Journal: Revue des maladies respiratoires 20091101

Title: Successful nonoperative management of gastrointestinal mucormycosis: novel therapy for invasive disease.

Journal: Surgical infections 20091001

Title: Atypical Aspergillus flavus isolates associated with chronic azole therapy.

Journal: Journal of clinical microbiology 20091001

Title: Disseminated zygomycosis with involvement of the central nervous system.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001

Title: In vitro activity of antifungals against Zygomycetes.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001

Title: Current experience in treating invasive zygomycosis with posaconazole.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001

Title: Hyperbaric oxygen therapy and other adjunctive treatments for zygomycosis.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001

Title: Evaluating the resistance to posaconazole by E-test and CLSI broth microdilution methodologies of Candida spp. and pathogenic moulds.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090901

Title: ZYGOMYCOSIS: current approaches to management of patients with haematological malignancies.

Journal: British journal of haematology 20090901

Title: A high-throughput LC-MS/MS method for the quantitation of posaconazole in human plasma: Implementing fused core silica liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20090815

Title: Determination of the antifungal agent posaconazole in human serum by HPLC with parallel column-switching technique.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815

Title: Limited penetration of posaconazole into cerebrospinal fluid in an allogeneic stem cell recipient with invasive pulmonary aspergillosis.

Journal: Bone marrow transplantation 20090801

Title: In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.

Journal: Antimicrobial agents and chemotherapy 20090801

Title: Efficacy of triazoles in a murine disseminated infection by Candida krusei.

Journal: Antimicrobial agents and chemotherapy 20090801

Title: Fatal rhizopus pneumonia in allogeneic stem cell transplant patients despite posaconazole prophylaxis: two cases and review of the literature.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090801

Title: What should be the first-choice strategy to maximize posaconazole exposure in daily clinical practice?

Journal: Antimicrobial agents and chemotherapy 20090801

Title: Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers.

Journal: Journal of acquired immune deficiency syndromes (1999) 20090801

Title: Posaconazole-induced topiramate toxicity.

Journal: Annals of internal medicine 20090721

Title: Treatment of intestinal and hepatic mucormycosis in an immunocompromized child.

Journal: Pediatric blood & cancer 20090701

Title: Simultaneous determination of voriconazole and posaconazole concentrations in human plasma by high-performance liquid chromatography.

Journal: Antimicrobial agents and chemotherapy 20090701

Title: Pharmacokinetics of posaconazole administered orally or by nasogastric tube in healthy volunteers.

Journal: Antimicrobial agents and chemotherapy 20090701

Title: Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease.

Journal: Journal of medicinal chemistry 20090625

Title: Recent advances in the management of mucormycosis: from bench to bedside.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615

Title: Long-term posaconazole treatment and follow-up of rhino-orbital-cerebral mucormycosis in a diabetic girl.

Journal: Pediatric diabetes 20090601

Title: Safe management of tacrolimus together with posaconazole in lung transplant patients with cystic fibrosis.

Journal: Therapeutic drug monitoring 20090601

Title: Dynamics of in vitro acquisition of resistance by Candida parapsilosis to different azoles.

Journal: FEMS yeast research 20090601

Title: Cutaneous infection caused by Macrophomina phaseolina in a child with acute myeloid leukemia.

Journal: Journal of clinical microbiology 20090601

Title: Tolerability and safety profile of posaconazole: evaluation of 18 controlled studies in healthy volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20090601

Title: Successful therapy with ABLC, surgery and posaconazole for Rhizopus microsporus var. rhizopodiformis liver eumycetoma in a child with acute leukaemia.

Journal: Mycoses 20090501

Title: Triazole-resistant candidaemia following posaconazole exposure.

Journal: International journal of antimicrobial agents 20090501

Title: Posaconazole therapeutic drug monitoring: a reference laboratory experience.

Journal: Antimicrobial agents and chemotherapy 20090501

Title: The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Prevention of mould infections.

Journal: The Journal of antimicrobial chemotherapy 20090501

Title: Diagnosis and treatment of aspergillosis in children.

Journal: Expert review of anti-infective therapy 20090501

Title: Rhinocerebral mucormycosis.

Journal: British journal of hospital medicine (London, England : 2005) 20090501

Title: Trichosporon mucoides fungemia in a liver transplant recipient: case report and review.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20090401

Title: Mucor circinelloides as a cause of invasive maxillofacial zygomycosis: an emerging dimorphic pathogen with reduced susceptibility to posaconazole.

Journal: Journal of clinical microbiology 20090401

Title: Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Interactions between triazoles and amphotericin B in treatment of disseminated murine infection by Fusarium oxysporum.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: A comparison of the fungicidal activity of amphotericin B and posaconazole against Zygomycetes in vitro.

Journal: Diagnostic microbiology and infectious disease 20090401

Title: Posaconazole for bone-invading rhinomaxillary mucormycosis.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090401

Title: Posaconazole-increased vincristine neurotoxicity in a child: a case report.

Journal: Journal of pediatric hematology/oncology 20090401

Title: Rational modification of a candidate cancer drug for use against Chagas disease.

Journal: Journal of medicinal chemistry 20090326

Title: Omeprazole significantly reduces posaconazole serum trough level.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090315

Title: Susceptibility testing of Cryptococcus diffluens against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole and posaconazole.

Journal: Medical mycology 20090301

Title: Pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers.

Journal: Antimicrobial agents and chemotherapy 20090301

Title: Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery.

Journal: Medical mycology 20090301

Title: Effects of oral posaconazole on the pharmacokinetics of sirolimus.

Journal: Current medical research and opinion 20090301

Title: Posaconazole's impact on prophylaxis and treatment of invasive fungal infections: an update.

Journal: Expert review of anti-infective therapy 20090301

Title: Posaconazole mono- or combination therapy for treatment of murine zygomycosis.

Journal: Antimicrobial agents and chemotherapy 20090201

Title: Intrapulmonary pharmacokinetics and pharmacodynamics of posaconazole at steady state in healthy subjects.

Journal: Antimicrobial agents and chemotherapy 20090201

Title: Posaconazole efficacy in a murine disseminated infection caused by Paecilomyces lilacinus.

Journal: The Journal of antimicrobial chemotherapy 20090201

Title: Antifungal susceptibility testing of Exophiala spp.: a head-to-head comparison of amphotericin B, itraconazole, posaconazole and voriconazole.

Journal: Medical mycology 20090201

Title: Posaconazole: a new oral antifungal agent with an expanded spectrum of activity.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090201

Title: Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers.

Journal: Clinical therapeutics 20090201

Title: [Amphotericin and posaconazole for gastrointestinal mucormycosis].

Journal: Revista espanola de anestesiologia y reanimacion 20090201

Title: Rhino-cerebral zygomycosis resistant to antimycotic treatment: a case report.

Journal: Mycoses 20090101

Title: Successful treatment of relapsing disseminated coccidioidomycosis with cutaneous involvement with posaconazole.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090101

Title: Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans.

Journal: Antimicrobial agents and chemotherapy 20090101

Title: Absence of CD4+ T lymphocytes, CD8+ T lymphocytes, or B lymphocytes has different effects on the efficacy of posaconazole and benznidazole in treatment of experimental acute Trypanosoma cruzi infection.

Journal: Antimicrobial agents and chemotherapy 20090101

Title: International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations.

Journal: Antimicrobial agents and chemotherapy 20090101

Title: Voriconazole and posaconazole resistant Candida pelliculosa fungemia after cardiac surgery.

Journal: The Pediatric infectious disease journal 20090101

Title: An increasing trend of cutaneous zygomycosis caused by Mycocladus corymbifer (formerly Absidia corymbifera): report of two cases and review of primary cutaneous Mycocladus infections.

Journal: Medical mycology 20090101

Title: A routine method for the quantification of the novel antimycotic drug posaconazole in plasma using liquid chromatography-tandem mass spectrometry.

Journal: Clinical chemistry and laboratory medicine 20090101

Title: Successful treatment of Cryptococcal meningitis with a combination of liposomal amphotericin B, flucytosine and posaconazole: two case reports.

Journal: In vivo (Athens, Greece) 20090101

Title: Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient.

Journal: Clinical drug investigation 20090101

Title: Primary cutaneous mucormycosis in a lung transplant recipient: case report and concise review of the literature.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20081201

Title: Breakthrough invasive fungal infection in an immunocompromised host while on posaconazole prophylaxis: an omission in patient counseling and follow-up.

Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20081201

Title: Economic evaluation of posaconazole vs. standard azole prophylaxis in high risk neutropenic patients in the Netherlands.

Journal: European journal of haematology 20081201

Title: Posaconazole concentrations in the central nervous system.

Journal: The Journal of antimicrobial chemotherapy 20081201

Title: Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment.

Journal: The Journal of antimicrobial chemotherapy 20081201

Title: Comparative cost-effectiveness of posaconazole versus fluconazole or itraconazole prophylaxis in patients with prolonged neutropenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081201

Title: [Trends in development of new antifungal agents in Japan].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20081201

Title: Clinical experience with posaconazole in patients with invasive mucormycosis: a case series.

Journal: Puerto Rico health sciences journal 20081201

Title: [Invasive pulmonary mucormycosis with invasion of the thoracic spine in a patient with myelodysplastic syndrome].

Journal: Revue medicale de Liege 20081201

Title: Disseminated Saksenaea vasiformis in an immunocompetent host.

Journal: The Medical journal of Australia 20081103

Title: Posaconazole as first line treatment for disseminated zygomycosis.

Journal: Mycoses 20081101

Title: [Posaconazole: another triazole antifungal of the new generation?].

Journal: Deutsche medizinische Wochenschrift (1946) 20081101

Title: In vitro susceptibility of Pythium insidiosum and a Lagenidium sp to itraconazole, posaconazole, voriconazole, terbinafine, caspofungin, and mefenoxam.

Journal: American journal of veterinary research 20081101

Title: Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism.

Journal: PLoS medicine 20081101

Title: Fatal Aspergillus fumigatus and Candida glabrata infections with posaconazole prophylaxis after stem cell transplantation.

Journal: International journal of antimicrobial agents 20081001

Title: Breakthrough Rhizopus infection on posaconazole prophylaxis following allogeneic stem cell transplantation.

Journal: Bone marrow transplantation 20081001

Title: Infection of the subcutis of the nose in a cat caused by Mucor species: successful treatment using posaconazole.

Journal: Journal of feline medicine and surgery 20081001

Title: Comparison of posaconazole and voriconazole in vitro killing against Candida krusei.

Journal: Diagnostic microbiology and infectious disease 20081001

Title: Activities of antifungal agents against yeasts and filamentous fungi: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing.

Journal: Antimicrobial agents and chemotherapy 20081001

Title: Posaconazole combined with amphotericin B, an effective therapy for a murine disseminated infection caused by Rhizopus oryzae.

Journal: Antimicrobial agents and chemotherapy 20081001

Title: Posaconazole: an oral triazole with an extended spectrum of activity.

Journal: The Annals of pharmacotherapy 20081001

Title: Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome.

Journal: Pharmacotherapy 20081001

Title: Adverse drug events complicate antifungal therapy for pulmonary aspergilloma.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20081001

Title: Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant.

Journal: Transplantation 20080927

Title: Does pre-exposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively? A study in a fly model of aspergillosis.

Journal: The Journal of antimicrobial chemotherapy 20080901

Title: Investigation and management of an outbreak of mucormycosis in a paediatric oncology unit.

Journal: The Journal of hospital infection 20080901

Title: Trends in species distribution and susceptibility of bloodstream isolates of Candida collected in Monterrey, Mexico, to seven antifungal agents: results of a 3-year (2004 to 2007) surveillance study.

Journal: Journal of clinical microbiology 20080901

Title: Breakpoints for posaconazole susceptibility testing: background and discussion about the need of establishing values.

Journal: Mycoses 20080901

Title: Posaconazole for paediatric patients: status of development and future perspectives.

Journal: Mycoses 20080901

Title: Invasive candidiasis in the ICU: evidence based and on the edge of evidence.

Journal: Mycoses 20080901

Title: Posaconazole in intensive care patients I: invasive fungal infections in surgical intensive care and case presentation.

Journal: Mycoses 20080901

Title: Comparative in vitro activities of posaconazole, voriconazole, itraconazole, and amphotericin B against Aspergillus and Rhizopus, and synergy testing for Rhizopus.

Journal: Medical mycology 20080901

Title: In vitro susceptibilities of invasive isolates of Candida species: rapid increase in rates of fluconazole susceptible-dose dependent Candida glabrata isolates.

Journal: Antimicrobial agents and chemotherapy 20080801

Title: Breakthrough disseminated Scedosporium prolificans infection in a patient with relapsed leukaemia on prolonged voriconazole followed by posaconazole prophylaxis.

Journal: Mycopathologia 20080801

Title: Treatment of aspergillosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080801

Title: [In vitro susceptibility of isolates of Scytalidium spp. from superficial lesions against posaconazole].

Journal: Pathologie-biologie 20080701

Title: MICs and minimum fungicidal concentrations of posaconazole, voriconazole and fluconazole for Cryptococcus neoformans and Cryptococcus gattii.

Journal: The Journal of antimicrobial chemotherapy 20080701

Title: Posaconazole enhances the activity of amphotericin B against hyphae of zygomycetes in vitro.

Journal: Antimicrobial agents and chemotherapy 20080701

Title: In vitro susceptibility of Cryptococcus gattii clinical isolates.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080701

Title: In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum.

Journal: Antimicrobial agents and chemotherapy 20080601

Title: Posaconazole against Candida glabrata isolates with various susceptibilities to fluconazole.

Journal: Antimicrobial agents and chemotherapy 20080601

Title: [New systemic antifungal drugs].

Journal: La Revue de medecine interne 20080601

Title: Numbers needed to treat with posaconazole prophylaxis to prevent invasive fungal infection and death.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515

Title: The effect of gastric Acid on the absorption of posaconazole.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515

Title: Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).

Journal: Journal of mass spectrometry : JMS 20080401

Title: Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei.

Journal: Antimicrobial agents and chemotherapy 20080401

Title: Mucormycoses: serious complication of high-dose corticosteroid therapy for traumatic optic neuropathy.

Journal: International journal of oral and maxillofacial surgery 20080401

Title: Therapeutic drug monitoring of antifungals: pharmacokinetic and pharmacodynamic considerations.

Journal: Therapeutic drug monitoring 20080401

Title: Beta-D-glucan detection test: a step toward preemptive therapy for fungal infections in leukemic patients?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080315

Title: Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin.

Journal: Leukemia 20080301

Title: In vitro activities of combinations of amphotericin B, posaconazole and four other agents against Rhizopus.

Journal: The Journal of antimicrobial chemotherapy 20080301

Title: Interaction of amphotericin B lipid formulations and triazoles with human polymorphonuclear leucocytes for antifungal activity against Zygomycetes.

Journal: Mycoses 20080301

Title: Successfully treated Candida krusei infection of the lumbar spine with combined caspofungin/posaconazole therapy.

Journal: Medical mycology 20080201

Title: Effect of calcineurin inhibitors on posaconazole blood levels as measured by the MVista microbiological assay.

Journal: Antimicrobial agents and chemotherapy 20080201

Title: Posaconazole activity against Candida glabrata after exposure to caspofungin or amphotericin B.

Journal: Antimicrobial agents and chemotherapy 20080201

Title: Selection of a surrogate agent (fluconazole or voriconazole) for initial susceptibility testing of posaconazole against Candida spp.: results from a global antifungal surveillance program.

Journal: Journal of clinical microbiology 20080201

Title: Mucormycosis peritonitis: more than 2 years of disease-free follow-up after posaconazole salvage therapy after failure of liposomal amphotericin B.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080201

Title: Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: point.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20080201

Title: Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: counterpoint.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20080201

Title: [Antifungal activity of posaconazole and caspofungin in yeast causing invasive fungal infection (2002-2003). E-test system evaluation].

Journal: Enfermedades infecciosas y microbiologia clinica 20080201

Title: Comparison of disc diffusion assay with the CLSI reference method (M27-A2) for testing in vitro posaconazole activity against common and uncommon yeasts.

Journal: The Journal of antimicrobial chemotherapy 20080101

Title: Treatment of zygomycosis: current and new options.

Journal: The Journal of antimicrobial chemotherapy 20080101

Title: Progressive fusariosis: unpredictable posaconazole bioavailability, and feasibility of recombinant interferon-gamma plus granulocyte macrophage-colony stimulating factor for refractory disseminated infection.

Journal: Leukemia & lymphoma 20080101

Title: Posaconazole : a review of its use in the prophylaxis of invasive fungal infections.

Journal: Drugs 20080101

Title: Antifungal agents--clinical pharmacokinetics and drug interactions.

Journal: Mycoses 20080101

Title: Development and validation of a high-performance liquid chromatography assay for posaconazole utilizing solid-phase extraction.

Journal: Clinical chemistry and laboratory medicine 20080101

Title: Reviews of anti-infective agents: posaconazole: a broad-spectrum triazole antifungal agent.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071215

Title: Efficacy of caspofungin and posaconazole in a murine model of disseminated Exophiala infection.

Journal: Medical mycology 20071201

Title: Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease.

Journal: Pharmacotherapy 20071201

Title: A review of the new antifungals: posaconazole, micafungin, and anidulafungin.

Journal: Journal of drugs in dermatology : JDD 20071201

Title: [Invasive zygomycosis in patients treated for haematological malignancies].

Journal: Nederlands tijdschrift voor geneeskunde 20071124

Title: Breakthrough infection of Trichosporon asahii during posaconazole treatment in a patient with acute myeloid leukaemia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20071101

Title: Efficacy of posaconazole and amphotericin B in experimental invasive pulmonary aspergillosis in dexamethasone immunosuppressed rats.

Journal: The Journal of antimicrobial chemotherapy 20071101

Title: Correlation of posaconazole minimum fungicidal concentration and time kill test against nine Candida species.

Journal: The Journal of antimicrobial chemotherapy 20071101

Title: Antifungal agents.

Journal: The Medical journal of Australia 20071001

Title: Lack of cross-hepatotoxicity between voriconazole and posaconazole.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070915

Title: Posaconazole therapy for chronic refractory coccidioidomycosis.

Journal: Chest 20070901

Title: Synergistic effect of posaconazole and caspofungin against clinical zygomycetes.

Journal: Antimicrobial agents and chemotherapy 20070901

Title: In vitro susceptibility to posaconazole of 1,903 yeast isolates recovered in France from 2003 to 2006 and tested by the method of the European committee on antimicrobial susceptibility testing.

Journal: Antimicrobial agents and chemotherapy 20070901

Title: Early use of posaconazole in the successful treatment of rhino-orbital mucormycosis caused by Rhizopus oryzae.

Journal: The Journal of infection 20070901

Title: Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070901

Title: Posaconazole for invasive aspergillosis?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070901

Title: Recalcitrant Beauveria bassiana keratitis: confocal microscopy findings and treatment with posaconazole (Noxafil).

Journal: Cornea 20070901

Title: Posaconazole: an extended-spectrum triazole antifungal agent.

Journal: Clinical therapeutics 20070901

Title: In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.

Journal: Antimicrobial agents and chemotherapy 20070701

Title: Evaluation of Etest and disk diffusion methods compared with broth microdilution antifungal susceptibility testing of clinical isolates of Candida spp. against posaconazole.

Journal: Journal of clinical microbiology 20070601

Title: Clinical evaluation of the Sensititre YeastOne plate for testing susceptibility of filamentous fungi to posaconazole.

Journal: Journal of clinical microbiology 20070601

Title: Multicenter evaluation of a new disk agar diffusion method for susceptibility testing of filamentous fungi with voriconazole, posaconazole, itraconazole, amphotericin B, and caspofungin.

Journal: Journal of clinical microbiology 20070601

Title: Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20070601

Title: Successful treatment of disseminated fusariosis with posaconazole during neutropenia and subsequent allogeneic hematopoietic stem cell transplantation.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20070601

Title: Inherited long QT syndrome revealed by antifungals drug-drug interaction.

Journal: Journal of clinical pharmacy and therapeutics 20070601

Title: Posaconazole: a new broad-spectrum antifungal agent.

Journal: Expert opinion on pharmacotherapy 20070601

Title: Effect of oral posaconazole on the pharmacokinetics of cyclosporine and tacrolimus.

Journal: Pharmacotherapy 20070601

Title: Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men.

Journal: Current medical research and opinion 20070601

Title: Antimicrobial susceptibility of Fusarium, Aspergillus, and other filamentous fungi isolated from keratitis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20070601

Title: Rhino-orbital mucormycosis causing cavernous sinus and internal carotid thrombosis treated with posaconazole.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20070601

Title: Posaconazole: a next-generation triazole antifungal.

Journal: Future microbiology 20070601

Title: Posaconazole for the management of mucosal candidiasis.

Journal: Future microbiology 20070601

Title: Posaconazole prophylaxis in hematologic cancer.

Journal: The New England journal of medicine 20070524

Title: Posaconazole prophylaxis in hematologic cancer.

Journal: The New England journal of medicine 20070524

Title: Posaconazole prophylaxis in hematologic cancer.

Journal: The New England journal of medicine 20070524

Title: Posaconazole prophylaxis in hematologic cancer.

Journal: The New England journal of medicine 20070524

Title: Posaconazole treatment for Apophysomyces elegans rhino-orbital zygomycosis following trauma for a male with well-controlled diabetes.

Journal: Journal of clinical microbiology 20070501

Title: Rhizopus microsporus var. rhizopodiformis sinus-orbital zygomycosis in an immunosuppressed patient: successful treatment with posaconazole after a complicated clinical course.

Journal: Journal of medical microbiology 20070501

Title: Mucormycosis in patients with complicated cirrhosis.

Journal: Singapore medical journal 20070501

Title: Therapeutic efficacy of posaconazole against isolates of Candida albicans with different susceptibilities to fluconazole in a vaginal model.

Journal: Medical mycology 20070501

Title: Posaconazole susceptibility testing against Candida species: comparison of broth microdilution and E-test methods.

Journal: Mycoses 20070501

Title: [Correlations among itraconazole, voriconazole and posaconazole MICs in Aspergillus fumigatus].

Journal: Enfermedades infecciosas y microbiologia clinica 20070501

Title: Posaconazole for azole-refractory candidiasis in patients with HIV infection.

Journal: AIDS alert 20070501

Title: Salvage treatment of histoplasmosis with posaconazole.

Journal: The Journal of infection 20070401

Title: The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole.

Journal: Antimicrobial agents and chemotherapy 20070401

Title: Evaluation of disk diffusion and Etest compared to broth microdilution for antifungal susceptibility testing of posaconazole against clinical isolates of filamentous fungi.

Journal: Journal of clinical microbiology 20070401

Title: Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia.

Journal: Pediatric blood & cancer 20070301

Title: Posaconazole plasma concentrations in juvenile patients with invasive fungal infection.

Journal: Antimicrobial agents and chemotherapy 20070301

Title: Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men.

Journal: Current medical research and opinion 20070301

Title: Posaconazole.

Journal: Nature reviews. Drug discovery 20070301

Title: Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole.

Journal: Hawaii medical journal 20070301

Title: Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070215

Title: Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers.

Journal: Antimicrobial agents and chemotherapy 20070201

Title: Posaconazole enhances the activity of amphotericin B against Aspergillus hyphae in vitro.

Journal: Antimicrobial agents and chemotherapy 20070201

Title: Posaconazole as salvage therapy in a patient with disseminated zygomycosis: case report and review of the literature.

Journal: Pharmacotherapy 20070201

Title: Successful treatment of resistant ocular fusariosis with posaconazole (SCH-56592).

Journal: American journal of ophthalmology 20070201

Title: Drug approvals.

Journal: The Nurse practitioner 20070201

Title: [The latest data on posaconazole].

Journal: Medecine et maladies infectieuses 20070201

Title: Possible increase of the neurotoxicity of vincristine by the concurrent use of posaconazole in a young adult with leukemia.

Journal: Journal of pediatric hematology/oncology 20070201

Title: Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease.

Journal: The New England journal of medicine 20070125

Title: Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.

Journal: The New England journal of medicine 20070125

Title: Prophylaxis and aspergillosis--has the principle been proven?

Journal: The New England journal of medicine 20070125

Title: A sensitive liquid chromatography and mass spectrometry method for the determination of posaconazole in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070104

Title: Posaconazole prophylaxis in experimental systemic zygomycosis.

Journal: Antimicrobial agents and chemotherapy 20070101

Title: Quality control limits for posaconazole disk susceptibility tests on Mueller-Hinton agar with glucose and methylene blue.

Journal: Journal of clinical microbiology 20070101

Title: Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070101

Title: Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection.

Journal: HIV clinical trials 20070101

Title: Rhinocerebral mucormycosis with perineural spread.

Journal: Ophthalmic plastic and reconstructive surgery 20070101

Title: Changing epidemiology of rare mould infections: implications for therapy.

Journal: Drugs 20070101

Title: Update on new antifungal therapy.

Journal: AACN advanced critical care 20070101

Title: Successful treatment of pulmonary zygomycosis with posaconazole in a recipient of a haploidentical donor stem cell transplant.

Journal: Pediatric blood & cancer 20061201

Title: Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.

Journal: Antimicrobial agents and chemotherapy 20061201

Title: Posaconazole (Noxafil) for invasive fungal infections.

Journal: The Medical letter on drugs and therapeutics 20061120

Title: Evaluation of automated micro solid phase extraction tips (micro-SPE) for the validation of a LC-MS/MS bioanalytical method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107

Title: Molecular basis for enhanced activity of posaconazole against Absidia corymbifera and Rhizopus oryzae.

Journal: Antimicrobial agents and chemotherapy 20061101

Title: Chronic refractory phaeohyphomycosis: successful treatment with posaconazole.

Journal: Mycoses 20061101

Title: Multi-azole resistance in Aspergillus fumigatus.

Journal: International journal of antimicrobial agents 20061101

Title: New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061015

Title: Comparison of three commercial assays and a modified disk diffusion assay with two broth microdilution reference assays for testing zygomycetes, Aspergillus spp., Candida spp., and Cryptococcus neoformans with posaconazole and amphotericin B.

Journal: Journal of clinical microbiology 20061001

Title: Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901

Title: Comparison of the EUCAST-AFST broth dilution method with the CLSI reference broth dilution method (M38-A) for susceptibility testing of posaconazole and voriconazole against Aspergillus spp.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060901

Title: Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole.

Journal: The Annals of thoracic surgery 20060701

Title: Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection.

Journal: Antimicrobial agents and chemotherapy 20060701

Title: Periorbital zygomycosis (mucormycosis) treated with posaconazole.

Journal: American journal of ophthalmology 20060701

Title: First case of Penicillium marneffei fungemia in Greece and strain susceptibility to five licensed systemic antifungal agents and posaconazole.

Journal: The American journal of the medical sciences 20060701

Title: Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060615

Title: Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors.

Journal: International journal of antimicrobial agents 20060601

Title: Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients.

Journal: Antimicrobial agents and chemotherapy 20060601

Title: In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts.

Journal: Antimicrobial agents and chemotherapy 20060601

Title: In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

Journal: Antimicrobial agents and chemotherapy 20060601

Title: Newer triazole antifungal agents: pharmacology, spectrum, clinical efficacy and limitations.

Journal: Expert opinion on investigational drugs 20060601

Title: Importance of identification of zygomycetes in the era of newer antifungal agents.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20060601

Title: Correlation between microdilution, E-test, and disk diffusion methods for antifungal susceptibility testing of posaconazole against Candida spp.

Journal: Journal of clinical microbiology 20060601

Title: Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060515

Title: Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers.

Journal: Antimicrobial agents and chemotherapy 20060501

Title: Control of a Candida glabrata prosthetic endovascular infection with posaconazole.

Journal: Medical mycology 20060501

Title: A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

Title: Oropharyngeal candidiasis: a new treatment option.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

Title: Posaconazole is effective as salvage therapy in zygomycosis: a retrospective summary of 91 cases.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060401

Title: Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

Journal: Antimicrobial agents and chemotherapy 20060301

Title: Evaluation of disk diffusion method for determining posaconazole susceptibility of filamentous fungi: comparison with CLSI broth microdilution method.

Journal: Antimicrobial agents and chemotherapy 20060301

Title: Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.

Journal: Journal of medicinal chemistry 20060209

Title: Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection.

Journal: Antimicrobial agents and chemotherapy 20060201

Title: Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].

Journal: Bioorganic & medicinal chemistry letters 20060101

Title: Posaconazole as salvage therapy for zygomycosis.

Journal: Antimicrobial agents and chemotherapy 20060101

Title: Epidemiology of candidaemia and antifungal susceptibility patterns in an Italian tertiary-care hospital.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060101

Title: Use of posaconazole in the management of invasive orbital aspergillosis in a cat.

Journal: Journal of the American Animal Hospital Association 20060101

Title: A new, broad-spectrum azole antifungal: posaconazole--mechanisms of action and resistance, spectrum of activity.

Journal: Mycoses 20060101

Title: Antifungal efficacy and pharmacodynamics of posaconazole in experimental models of invasive fungal infections.

Journal: Mycoses 20060101

Title: HPLC analysis of the antifungal agent posaconazole in patients with haematological diseases.

Journal: Mycoses 20060101

Title: Second-line treatment in invasive mould infections.

Journal: Mycoses 20060101

Title: Successful treatment of disseminated mucormycosis with a combination of liposomal amphotericin B and posaconazole in a patient with acute myeloid leukaemia.

Journal: Mycoses 20060101

Title: Rhinocerebral zygomycosis in a young girl undergoing allogeneic stem cell transplantation for severe aplastic anaemia.

Journal: Mycoses 20060101

Title: Posaconazole for treatment of refractory invasive fungal disease.

Journal: Mycoses 20060101

Title: Salvage therapy of refractory chronic disseminated candidiasis in a patient with acute myeloid leukaemia and secondary prophylaxis during allogeneic stem cell transplantation.

Journal: Mycoses 20060101

Title: New drugs: ranibizumab, posaconazole, and darunavir.

Journal: Journal of the American Pharmacists Association : JAPhA 20060101

Title: Novel medicine to prevent fungal infections.

Journal: FDA consumer 20060101

Title: Posaconazole: a broad-spectrum triazole antifungal.

Journal: The Lancet. Infectious diseases 20051201

Title: Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: recovery after posaconazole therapy.

Journal: Transplantation 20051115

Title: Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report.

Journal: Mycoses 20051101

Title: Mucormycoses in patients with hematologic malignancies: an emerging fungal infection.

Journal: Haematologica 20051101

Title: What does 'culture of life' mean for an undocumented immigrant?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015

Title: Activity of posaconazole in the treatment of central nervous system fungal infections.

Journal: The Journal of antimicrobial chemotherapy 20051001

Title: Quality control and reference guidelines for CLSI broth microdilution susceptibility method (M 38-A document) for amphotericin B, itraconazole, posaconazole, and voriconazole.

Journal: Journal of clinical microbiology 20051001

Title: Advances in antifungal therapy.

Journal: The Pediatric infectious disease journal 20051001

Title: Absidia posttraumatic infection: successful treatment with posaconazole.

Journal: The Journal of infection 20051001

Title: A case of disseminated histoplasmosis successfully treated with the investigational drug posaconazole.

Journal: The Journal of infection 20051001

Title: Treatment of zygomycosis with posaconazole in a patient with acute myeloid leukemia.

Journal: Clinical advances in hematology & oncology : H&O 20051001

Title: Review of treatment of zygomycosis with posaconazole in a patient with acute myeloid leukemia.

Journal: Clinical advances in hematology & oncology : H&O 20051001

Title: Comparison of visual 24-hour and spectrophotometric 48-hour MICs to CLSI reference microdilution MICs of fluconazole, itraconazole, posaconazole, and voriconazole for Candida spp.: a collaborative study.

Journal: Journal of clinical microbiology 20050901

Title: [Physiological comportment and in vivo sensitivity of Sporothrix schenckii isolates maintained for 18 years by two preservation methods].

Journal: Revista iberoamericana de micologia 20050901

Title: Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: recovery after posaconazole therapy.

Journal: Transplantation 20050827

Title: In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata.

Journal: Antimicrobial agents and chemotherapy 20050801

Title: International and multicenter comparison of EUCAST and CLSI M27-A2 broth microdilution methods for testing susceptibilities of Candida spp. to fluconazole, itraconazole, posaconazole, and voriconazole.

Journal: Journal of clinical microbiology 20050801

Title: Lung infection due to opportunistic fungus, Phialemonium obovatum, in a bone marrow transplant recipient: an emerging infection with fungemia and Crohn disease-like involvement of the gastrointestinal tract.

Journal: Annals of diagnostic pathology 20050801

Title: Posaconazole: clinical pharmacology and potential for management of fungal infections.

Journal: Expert review of anti-infective therapy 20050801

Title: Refractory coccidioidomycosis treated with posaconazole.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050615

Title: Effect of media composition and in vitro activity of posaconazole, caspofungin and voriconazole against zygomycetes.

Journal: The Journal of antimicrobial chemotherapy 20050601

Title: Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050601

Title: Antifungal agents in children.

Journal: Pediatric clinics of North America 20050601

Title: Posaconazole.

Journal: Drugs of today (Barcelona, Spain : 1998) 20050601

Title: In vitro activities of new and established triazoles against opportunistic filamentous and dimorphic fungi.

Journal: Medical mycology 20050501

Title: Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections.

Journal: The Journal of antimicrobial chemotherapy 20050301

Title: In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species.

Journal: Medical mycology 20050301

Title: Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease.

Journal: Journal of clinical pharmacology 20050201

Title: Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo.

Journal: Antimicrobial agents and chemotherapy 20050201

Title: Detection of Aspergillus fumigatus and a mutation that confers reduced susceptibility to itraconazole and posaconazole by real-time PCR and pyrosequencing.

Journal: Journal of clinical microbiology 20050201

Title: Successful therapy of cerebral phaeohyphomycosis due to Ramichloridium mackenziei with the new triazole posaconazole.

Journal: Medical mycology 20050201

Title: Oral bioavailability of posaconazole in fasted healthy subjects: comparison between three regimens and basis for clinical dosage recommendations.

Journal: Clinical pharmacokinetics 20050101

Title: Posaconazole.

Journal: Drugs 20050101

Title: Posaconazole treatment of refractory eumycetoma and chromoblastomycosis.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20050101

Title: Successful treatment of Fusarium proliferatum pneumonia with posaconazole in a lung transplant recipient.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20041201

Title: Aspergillus terreus: an emerging amphotericin B-resistant opportunistic mold in patients with hematologic malignancies.

Journal: Cancer 20041001

Title: Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds.

Journal: Antimicrobial agents and chemotherapy 20041001

Title: Antifungal activities of posaconazole and granulocyte-macrophage colony-stimulating factor ex vivo and in mice with disseminated infection due to Scedosporium prolificans.

Journal: Antimicrobial agents and chemotherapy 20041001

Title: Efficacy of posaconazole in a murine model of central nervous system aspergillosis.

Journal: Antimicrobial agents and chemotherapy 20041001

Title: Clinical evaluation of the Sensititre YeastOne colorimetric antifungal plate for antifungal susceptibility testing of the new triazoles voriconazole, posaconazole, and ravuconazole.

Journal: Journal of clinical microbiology 20041001

Title: Posaconazole and amphotericin B combination therapy against Cryptococcus neoformans infection.

Journal: Antimicrobial agents and chemotherapy 20040901

Title: Disposition of posaconazole following single-dose oral administration in healthy subjects.

Journal: Antimicrobial agents and chemotherapy 20040901

Title: Zygomycosis in neutropenic patients with past Aspergillus infection: a role for posaconazole?

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040901

Title: Alternatives to amphotericin B for Candida rugosa infection.

Journal: The Journal of antimicrobial chemotherapy 20040801

Title: Effect of granulocyte colony-stimulating factor combination therapy on efficacy of posaconazole (SCH56592) in an inhalation model of murine pulmonary aspergillosis.

Journal: Antimicrobial agents and chemotherapy 20040801

Title: Challenges in designing animal studies to detect antagonism of polyene activity.

Journal: Antimicrobial agents and chemotherapy 20040801

Title: Use of fatty acid RPMI 1640 media for testing susceptibilities of eight Malassezia species to the new triazole posaconazole and to six established antifungal agents by a modified NCCLS M27-A2 microdilution method and Etest.

Journal: Journal of clinical microbiology 20040801

Title: Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles.

Journal: Antimicrobial agents and chemotherapy 20040601

Title: Posaconazole therapy of disseminated phaeohyphomycosis in a murine model.

Journal: Antimicrobial agents and chemotherapy 20040601

Title: Posaconazole: a potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections.

Journal: International journal of clinical practice 20040601

Title: Posaconazole therapy for severe abdominal candidiasis: a case report.

Journal: Revista iberoamericana de micologia 20040601

Title: [Fulminant invasive fungal sinusitis in immunosuppressed hosts -- pathognomic presentation in MRI].

Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20040501

Title: Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040401

Title: Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories.

Journal: Antimicrobial agents and chemotherapy 20040301

Title: Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men.

Journal: Antimicrobial agents and chemotherapy 20040301

Title: Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole.

Journal: Journal of clinical microbiology 20040301

Title: In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program.

Journal: Diagnostic microbiology and infectious disease 20040301

Title: Case study: posaconazole treatment of disseminated phaeohyphomycosis due to Exophiala spinifera.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040201

Title: Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

Journal: Antimicrobial agents and chemotherapy 20040201

Title: Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040201

Title: Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults.

Journal: British journal of clinical pharmacology 20040201

Title: Changes in susceptibility to posaconazole in clinical isolates of Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20040101

Title: Reversible dilated cardiomyopathy related to amphotericin B therapy.

Journal: The Journal of antimicrobial chemotherapy 20040101

Title: Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis.

Journal: Antimicrobial agents and chemotherapy 20040101

Title: In vitro antifungal activities of anidulafungin and micafungin, licensed agents and the investigational triazole posaconazole as determined by NCCLS methods for 12,052 fungal isolates: review of the literature.

Journal: Revista iberoamericana de micologia 20031201

Title: Activity of posaconazole in treatment of experimental disseminated zygomycosis.

Journal: Antimicrobial agents and chemotherapy 20031101

Title: Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults.

Journal: Antimicrobial agents and chemotherapy 20030901

Title: [Invasive aspergillosis: clinical manifestations and treatment].

Journal: Revista iberoamericana de micologia 20030901

Title: Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi.

Journal: Journal of clinical microbiology 20030801

Title: New antifungal agents.

Journal: Dermatologic clinics 20030701

Title: Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030601

Title: [In vitro activity of fluconazole, voriconazole and posaconazole against Candida spp].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030601

Title: Activity of posaconazole against Pseudallescheria boydii: in vitro and in vivo assays.

Journal: Antimicrobial agents and chemotherapy 20030401

Title: In vitro susceptibility testing of filamentous fungi: comparison of Etest and reference M38-A microdilution methods for determining posaconazole MICs.

Journal: Diagnostic microbiology and infectious disease 20030401

Title: Use of high-performance liquid chromatographic and microbiological analyses for evaluating the presence or absence of active metabolites of the antifungal posaconazole in human plasma.

Journal: Journal of chromatography. A 20030214

Title: Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.

Journal: Antimicrobial agents and chemotherapy 20030201

Title: In vitro activities of voriconazole, posaconazole, and four licensed systemic antifungal agents against Candida species infrequently isolated from blood.

Journal: Journal of clinical microbiology 20030101

Title: Posaconazole: SCH 56592.

Journal: Drugs in R&D 20030101

Title: [In vitro activity of posaconazole against yeasts isolated in blood cultures].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20021201

Title: [Present status and future prospects of azole antifungal agents in Japan].

Journal: The Japanese journal of antibiotics 20021201

Title: Laboratory evaluation of new antifungal agents against rare and refractory mycoses.

Journal: Current opinion in infectious diseases 20021201

Title: In vitro susceptibilities of cerebrospinal fluid isolates of Cryptococcus neoformans collected during a ten-year period against fluconazole, voriconazole and posaconazole (SCH56592).

Journal: Mycoses 20021101

Title: Acremonium strictum pulmonary infection in a leukemic patient successfully treated with posaconazole after failure of amphotericin B.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20021101

Title: In vitro activities of investigational triazoles against Fusarium species: effects of inoculum size and incubation time on broth microdilution susceptibility test results.

Journal: Antimicrobial agents and chemotherapy 20021001

Title: Antifungal triazoles and polymorphonuclear leukocytes synergize to cause increased hyphal damage to Scedosporium prolificans and Scedosporium apiospermum.

Journal: Antimicrobial agents and chemotherapy 20020701

Title: In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model.

Journal: Antimicrobial agents and chemotherapy 20020701

Title: Ocular and systemic posaconazole(SCH-56592) treatment of invasive Fusarium solani keratitis and endophthalmitis.

Journal: The British journal of ophthalmology 20020701

Title: In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients.

Journal: The Journal of antimicrobial chemotherapy 20020701

Title: Treatment of Scedosporium apiospermum brain abscesses with posaconazole.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020615

Title: E-test method for testing susceptibilities of Aspergillus spp. to the new triazoles voriconazole and posaconazole and to established antifungal agents: comparison with NCCLS broth microdilution method.

Journal: Journal of clinical microbiology 20020601

Title: Effect of medium composition on static and cidal activity of amphotericin B, itraconazole, voriconazole, posaconazole and terbinafine against Aspergillus fumigatus: a multicenter study.

Journal: Journal of chemotherapy (Florence, Italy) 20020601

Title: In vitro and in vivo activities of posaconazole against Coccidioides immitis.

Journal: Antimicrobial agents and chemotherapy 20020501

Title: Clinical evaluation of a frozen commercially prepared microdilution panel for antifungal susceptibility testing of seven antifungal agents, including the new triazoles posaconazole, ravuconazole, and voriconazole.

Journal: Journal of clinical microbiology 20020501

Title: Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000.

Journal: Antimicrobial agents and chemotherapy 20020401

Title: Genotyping and antifungal susceptibility of human subgingival Candida albicans isolates.

Journal: Archives of oral biology 20020301

Title: Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis.

Journal: Journal of mass spectrometry : JMS 20020301

Title: Azole cross-resistance in Aspergillus fumigatus.

Journal: Antimicrobial agents and chemotherapy 20020201

Title: Simultaneous high-performance liquid chromatographic determination of SCH 59884 (phosphate ester prodrug of SCH 56592), SCH 207962 and SCH 56592 in dog plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20020101

Title: Activity of the new antifungal triazole, posaconazole, against Cryptococcus neoformans.

Journal: The Journal of antimicrobial chemotherapy 20011201

Title: Aspergillus: rising frequency of clinical isolation and continued susceptibility to antifungal agents, 1994-1999.

Journal: Diagnostic microbiology and infectious disease 20011201

Title: Evaluation of Etest method for determining posaconazole MICs for 314 clinical isolates of Candida species.

Journal: Journal of clinical microbiology 20011101

Title: In vitro activity of posaconazole against clinical isolates of dermatophytes.

Journal: Journal of clinical microbiology 20011101

Title: In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans.

Journal: Antimicrobial agents and chemotherapy 20011001

Title: Antifungals: what's in the pipeline.

Journal: Current opinion in microbiology 20011001

Title: In vitro antifungal activity of posaconazole against various pathogenic fungi.

Journal: International journal of antimicrobial agents 20010801

Title: In vitro activities of four novel triazoles against Scedosporium spp.

Journal: Antimicrobial agents and chemotherapy 20010701

Title: Structural characterization of the oxidative degradation products of an antifungal agent SCH 56592 by LC-NMR and LC-MS.

Journal: Journal of pharmaceutical and biomedical analysis 20010601

Title: Treatment of histoplasmosis.

Journal: Seminars in respiratory infections 20010601

Title: Interactions of posaconazole and flucytosine against Cryptococcus neoformans.

Journal: Antimicrobial agents and chemotherapy 20010501

Title: Antifungal activity and pharmacokinetics of posaconazole (SCH 56592) in treatment and prevention of experimental invasive pulmonary aspergillosis: correlation with galactomannan antigenemia.

Journal: Antimicrobial agents and chemotherapy 20010301

Title: Isolation and in vitro susceptibility to amphotericin B, itraconazole and posaconazole of voriconazole-resistant laboratory isolates of Aspergillus fumigatus.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010301

Title: In vitro and in vivo activities of SCH 56592 (posaconazole), a new triazole antifungal agent, against Aspergillus and Candida.

Journal: Antimicrobial agents and chemotherapy 20000801

Title: In vitro activities of the new antifungal triazole SCH 56592 against common and emerging yeast pathogens.

Journal: Antimicrobial agents and chemotherapy 20000101

Title: In-vitro and in-vivo activities of SCH56592 against Cryptococcus neoformans.

Journal: The Journal of antimicrobial chemotherapy 19991201

Title: [New antifungal drugs. Present and future].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 19990901

Title: Current and emerging azole antifungal agents.

Journal: Clinical microbiology reviews 19990101

Title: In vitro susceptibilities of Candida bloodstream isolates to the new triazole antifungal agents BMS-207147, Sch 56592, and voriconazole.

Journal: Antimicrobial agents and chemotherapy 19981201

Title: Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts.

Journal: Journal of clinical microbiology 19981001

Title: SCH56592 treatment of murine invasive aspergillosis.

Journal: The Journal of antimicrobial chemotherapy 19981001

Title: In vitro activity of a new triazole antifungal agent, Sch 56592, against clinical isolates of filamentous fungi.

Journal: Mycopathologia 19980101

Title: Activity of SCH 56592 compared with those of fluconazole and itraconazole against Candida spp.

Journal: Antimicrobial agents and chemotherapy 19971001

Title: Activity of a new triazole, Sch 56592, compared with those of four other antifungal agents tested against clinical isolates of Candida spp. and Saccharomyces cerevisiae.

Journal: Antimicrobial agents and chemotherapy 19970201

Title: In vitro studies of activities of the antifungal triazoles SCH56592 and itraconazole against Candida albicans, Cryptococcus neoformans, and other pathogenic yeasts.

Journal: Antimicrobial agents and chemotherapy 19970101

Title: In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans.

Journal: Antimicrobial agents and chemotherapy 19960801

Title: Benaim G, et al. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. J Med Chem. 2006 Feb 9;49(3):892-9.

Title: Sabatelli F, et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob Agents Chemother. 2006 Jun;50(6):2009-15.

Title: Sansone-Parsons A, et al. Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers. Antimicrob Agents Chemother. 2006 May;50(5):1881-3.

Title: Veiga-Santos P, et al. Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents. 2012 Jul;40(1):61-71.

Title: Sun QN, et al. In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model. Antimicrob Agents Chemother. 2002 Jul;46(7):2310-2.

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Tags:171228-49-2 Molecular Formula|171228-49-2 MDL|171228-49-2 SMILES|171228-49-2 Posaconazole