Home Other Building Blocks 35354-74-6
35354-74-6,MFCD00016674
Catalog No.:AA0039JF

35354-74-6 | 2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
in stock  
$6.00   $4.00
- +
50mg
98%
in stock  
$8.00   $6.00
- +
1g
98%
in stock  
$13.00   $9.00
- +
5g
98%
in stock  
$41.00   $29.00
- +
25g
98%
in stock  
$183.00   $128.00
- +
100g
98%
in stock  
$591.00   $414.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0039JF
Chemical Name:
2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
CAS Number:
35354-74-6
Molecular Formula:
C18H18O2
Molecular Weight:
266.3343
MDL Number:
MFCD00016674
SMILES:
C=CCc1ccc(c(c1)c1ccc(c(c1)CC=C)O)O
NSC Number:
293100
Properties
Computed Properties
 
Complexity:
325  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
5  

Downstream Synthesis Route

[1]BioorganicandMedicinalChemistry,2019,vol.27,p.3729-3734

[2]BioorganicandMedicinalChemistryLetters,2005,vol.15,p.163-166

[3]Chemicalandpharmaceuticalbulletin,1972,vol.20,p.212-213

[4]BioorganicandMedicinalChemistry,2015,vol.23,p.6757-6762

[5]Molecules,2020,vol.25

[1]BioorganicandMedicinalChemistryLetters,2004,vol.14,p.2621-2625

[1]Patent:WO2008/99994,2008,A1.Locationinpatent:Page/Pagecolumn23-24

4530-20-5    35354-74-6   
C22H24N2O4*2ClH 

[1]Patent:WO2008/99994,2008,A1.Locationinpatent:Page/Pagecolumn21-22

15761-38-3    35354-74-6   
C24H28N2O4*2ClH 

[1]Patent:WO2008/99994,2008,A1.Locationinpatent:Page/Pagecolumn22-23

Literature

Title: Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.

Journal: Chemical research in toxicology 20170220

Title: Protective effects of honokiol against methylglyoxal-induced osteoblast damage.

Journal: Chemico-biological interactions 20160125

Title: The anti-inflammatory effect of 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol by targeting Lyn kinase in human neutrophils.

Journal: Chemico-biological interactions 20150705

Title: The mechanism of honokiol-induced intracellular Ca(2+) rises and apoptosis in human glioblastoma cells.

Journal: Chemico-biological interactions 20140925

Title: Anti-hepatitis C virus dinorditerpenes from the roots of Flueggea virosa.

Journal: Journal of natural products 20140124

Title: Trinorditerpenes from the roots of Flueggea virosa.

Journal: Bioorganic & medicinal chemistry letters 20140115

Title: Honokiol: a non-adipogenic PPARγ agonist from nature.

Journal: Biochimica et biophysica acta 20131001

Title: Surface enhancement of WO3 nanowires toward the oxidation and electrochemical detection of honokiol in traditional Chinese medicine.

Journal: Colloids and surfaces. B, Biointerfaces 20121201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice.

Journal: Journal of natural medicines 20121001

Title: Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice.

Journal: British journal of pharmacology 20121001

Title: Modulation of P-glycoprotein expression by honokiol, magnolol and 4-O-methylhonokiol, the bioactive components of Magnolia officinalis.

Journal: Anticancer research 20121001

Title: Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120901

Title: Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.

Journal: Chinese journal of integrative medicine 20120901

Title: A larval zebrafish model of bipolar disorder as a screening platform for neuro-therapeutics.

Journal: Behavioural brain research 20120801

Title: Design, synthesis, and anti-proliferative evaluation of [1,1'-biphenyl]-4-ols as inhibitor of HUVEC migration and tube formation.

Journal: Molecules (Basel, Switzerland) 20120705

Title: Multiple effects of Honokiol on the life cycle of hepatitis C virus.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20120701

Title: Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia.

Journal: Biochimica et biophysica acta 20120701

Title: Comparative studies on the interactions of honokiol and magnolol with human serum albumin.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: Honokiol inhibits HIF pathway and hypoxia-induced expression of histone lysine demethylases.

Journal: Biochemical and biophysical research communications 20120608

Title: Anti-HBV activities of Streblus asper and constituents of its roots.

Journal: Fitoterapia 20120601

Title: The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors.

Journal: Neuropharmacology 20120601

Title: Time and dose-response effects of honokiol on UVB-induced skin cancer development.

Journal: Drug discoveries & therapeutics 20120601

Title: Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.

Journal: Biochemical and biophysical research communications 20120525

Title: In vitro growth inhibition of human cancer cells by novel honokiol analogs.

Journal: Bioorganic & medicinal chemistry 20120515

Title: Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.

Journal: Journal of cellular physiology 20120501

Title: Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis.

Journal: Shock (Augusta, Ga.) 20120501

Title: [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120501

Title: Antimetastatic activity of honokiol in osteosarcoma.

Journal: Cancer 20120415

Title: Honokiol attenuates torsion/detorsion-induced testicular injury in rat testis by way of suppressing endoplasmic reticulum stress-related apoptosis.

Journal: Urology 20120401

Title: Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells.

Journal: Molecular cancer therapeutics 20120401

Title: Bioactive polar compounds from stem bark of Magnolia officinalis.

Journal: Fitoterapia 20120301

Title: Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway.

Journal: Neuro-oncology 20120301

Title: Synthesis and neurite growth evaluation of new analogues of honokiol, a neolignan with potent neurotrophic activity.

Journal: Bioorganic & medicinal chemistry letters 20120201

Title: Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals.

Journal: Intensive care medicine 20120201

Title: Anti-inflammatory effects of active constituents extracted from Chinese medicinal herbs against Propionibacterium acnes.

Journal: Natural product research 20120101

Title: Quality assessment of commercial Magnoliae officinalis Cortex by ¹H-NMR-based metabolomics and HPLC methods.

Journal: Phytochemical analysis : PCA 20120101

Title: The inhibitory effect of honokiol, a natural plant product, on vestibular schwannoma cells.

Journal: The Laryngoscope 20120101

Title: An expedient synthesis of honokiol and its analogues as potential neuropreventive agents.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Separation and determination of honokiol and magnolol in Chinese traditional medicines by capillary electrophoresis with the application of response surface methodology and radial basis function neural network.

Journal: Journal of chromatographic science 20120101

Title: Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models.

Journal: Journal of neuroinflammation 20120101

Title: Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.

Journal: Breast cancer research : BCR 20120101

Title: Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.

Journal: PloS one 20120101

Title: Therapeutic targeting of Krüppel-like factor 4 abrogates microglial activation.

Journal: Journal of neuroinflammation 20120101

Title: Phyllanthus urinaria Induces Apoptosis in Human Osteosarcoma 143B Cells via Activation of Fas/FasL- and Mitochondria-Mediated Pathways.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vitro and In Vivo.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: The metabolic syndrome and risk of chronic kidney disease: pathophysiology and intervention strategies.

Journal: Journal of nutrition and metabolism 20120101

Title: Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts.

Journal: PloS one 20120101

Title: Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents.

Journal: Frontiers in microbiology 20120101

Title: Porphyromonas gingivalis Fimbria-Induced Expression of Inflammatory Cytokines and Cyclooxygenase-2 in Mouse Macrophages and Its Inhibition by the Bioactive Compounds Fibronectin and Melatonin.

Journal: ISRN dentistry 20120101

Title: Syk/Src pathway-targeted inhibition of skin inflammatory responses by carnosic acid.

Journal: Mediators of inflammation 20120101

Title: NOXA-induced alterations in the Bax/Smac axis enhance sensitivity of ovarian cancer cells to cisplatin.

Journal: PloS one 20120101

Title: Application of ionic liquids in the microwave-assisted extraction of proanthocyanidins from Larix gmelini bark.

Journal: International journal of molecular sciences 20120101

Title: The effects of magnetite (Fe₃O₄) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH₃) cells and in RAW 264.7 macrophages.

Journal: International journal of nanomedicine 20120101

Title: Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro.

Journal: International journal of nanomedicine 20120101

Title: Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease.

Journal: Parkinson's disease 20120101

Title: Treating acute cystitis with biodegradable micelle-encapsulated quercetin.

Journal: International journal of nanomedicine 20120101

Title: Visualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modifications.

Journal: Sensors (Basel, Switzerland) 20120101

Title: Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes.

Journal: BioFactors (Oxford, England) 20120101

Title: Honokiol inhibits vascular vessel formation of mouse embryonic stem cell-derived endothelial cells via the suppression of PECAM and MAPK/mTOR signaling pathway.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice.

Journal: PloS one 20120101

Title: Modulating testosterone pathway: a new strategy to tackle male skin aging?

Journal: Clinical interventions in aging 20120101

Title: Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation.

Journal: International journal of molecular medicine 20111201

Title: Honokiol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111101

Title: Honokiol radiosensitizes colorectal cancer cells: enhanced activity in cells with mismatch repair defects.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20111101

Title: Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20111101

Title: [Honokiol-induced apoptosis of human non-Hodgkin lymphoma Raji cells and its possible mechanism].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111101

Title: Effect of honokiol on activity of GAD(65) and GAD(67) in the cortex and hippocampus of mice.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015

Title: Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: the evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship.

Journal: Journal of medicinal chemistry 20111013

Title: Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators.

Journal: International immunopharmacology 20111001

Title: Comparison of antioxidant abilities of magnolol and honokiol to scavenge radicals and to protect DNA.

Journal: Biochimie 20111001

Title: Targeting apoptosis pathways in cancer with magnolol and honokiol, bioactive constituents of the bark of Magnolia officinalis.

Journal: Drug discoveries & therapeutics 20111001

Title: Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915

Title: Honokiol produces anti-neoplastic effects on melanoma cells in vitro.

Journal: Journal of surgical oncology 20110901

Title: Honokiol inhibits LPS-induced maturation and inflammatory response of human monocyte-derived dendritic cells.

Journal: Journal of cellular physiology 20110901

Title: Honokiol attenuates vascular contraction through the inhibition of the RhoA/Rho-kinase signalling pathway in rat aortic rings.

Journal: The Journal of pharmacy and pharmacology 20110901

Title: Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110815

Title: Modulation of GABAA-receptors by honokiol and derivatives: subtype selectivity and structure-activity relationship.

Journal: Journal of medicinal chemistry 20110811

Title: Preparation, characterization, pharmacokinetics, and bioactivity of honokiol-in-hydroxypropyl-β-cyclodextrin-in-liposome.

Journal: Journal of pharmaceutical sciences 20110801

Title: In vitro metabolism and disposition of honokiol in rat and human livers.

Journal: Journal of pharmaceutical sciences 20110801

Title: Antimicrobial activity and cytotoxic effects of Magnolia dealbata and its active compounds.

Journal: Natural product communications 20110801

Title: Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes.

Journal: Journal of natural medicines 20110701

Title: Honokiol ameliorates renal fibrosis by inhibiting extracellular matrix and pro-inflammatory factors in vivo and in vitro.

Journal: British journal of pharmacology 20110601

Title: Honokiol inhibits hypoxia-inducible factor-1 pathway.

Journal: International journal of radiation biology 20110601

Title: Improved solubility and pharmacokinetics of PEGylated liposomal honokiol and human plasma protein binding ability of honokiol.

Journal: International journal of pharmaceutics 20110530

Title: Therapeutic applications of compounds in the Magnolia family.

Journal: Pharmacology & therapeutics 20110501

Title: Honokiol: an effective inhibitor of tumor necrosis factor-α-induced up-regulation of inflammatory cytokine and chemokine production in human synovial fibroblasts.

Journal: Acta biochimica et biophysica Sinica 20110501

Title: [Study on transport characteristics of honokiol in Caco-2 cell model by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501

Title: Effect of traditional Chinese medicinal herbs on Candida spp. from patients with HIV/AIDS.

Journal: Advances in dental research 20110401

Title: 5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway.

Journal: Experimental & molecular medicine 20110331

Title: Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells.

Journal: European journal of pharmacology 20110301

Title: Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2.

Journal: International journal of oncology 20110301

Title: Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation.

Journal: Intensive care medicine 20110301

Title: Honokiol inhibits H(2)O(2)-induced apoptosis in human lens epithelial cells via inhibition of the mitogen-activated protein kinase and Akt pathways.

Journal: European journal of pharmacology 20110110

Title: Evaluation of oxygen radical absorbance capacity in kampo medicine.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Distinct photoacidity of honokiol from magnolol.

Journal: Journal of fluorescence 20110101

Title: Protective Mechanism of KIOM-4 in Streptozotocin-Induced Pancreatic β-Cells Damage Is Involved in the Inhibition of Endoplasmic Reticulum Stress.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: KIOM-79 Prevents Lens Epithelial Cell Apoptosis and Lens Opacification in Zucker Diabetic Fatty Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Electrochemical detection of honokiol and magnolol in traditional Chinese medicines using acetylene black nanoparticle-modified electrode.

Journal: Phytochemical analysis : PCA 20110101

Title: Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages.

Journal: Journal of neuroinflammation 20110101

Title: Honokiol: a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells.

Journal: International journal of oral science 20110101

Title: Metabolic syndrome and renal injury.

Journal: Cardiology research and practice 20110101

Title: Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model.

Journal: PloS one 20110101

Title: Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts.

Journal: PloS one 20110101

Title: Particle Trajectories and Agglomeration/Accumulation in Branching Arteries subjected to Orbital Atherectomy.

Journal: The open biomedical engineering journal 20110101

Title: Network target for screening synergistic drug combinations with application to traditional Chinese medicine.

Journal: BMC systems biology 20110101

Title: Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.

Journal: PloS one 20110101

Title: Cathelicidin-BF, a snake cathelicidin-derived antimicrobial peptide, could be an excellent therapeutic agent for acne vulgaris.

Journal: PloS one 20110101

Title: KIOM-4 Protects against Oxidative Stress-Induced Mitochondrial Damage in Pancreatic β-cells via Its Antioxidant Effects.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Hepatoprotective activity of the Phyllanthus species on tert-butyl hydroperoxide (t-BH)-induced cytotoxicity in HepG2 cells.

Journal: Pharmacognosy magazine 20110101

Title: Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells.

Journal: International journal of nanomedicine 20110101

Title: Effect of herbal extract granules combined with probiotic mixture on irritable bowel syndrome with diarrhea: study protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: Effects of magnolol on UVB-induced skin cancer development in mice and its possible mechanism of action.

Journal: BMC cancer 20110101

Title: PI3K functions in cancer progression, anticancer immunity and immune evasion by tumors.

Journal: Clinical & developmental immunology 20110101

Title: Transcriptional and functional analysis of the effects of magnolol: inhibition of autolysis and biofilms in Staphylococcus aureus.

Journal: PloS one 20110101

Title: Flavonoids: A versatile source of anticancer drugs.

Journal: Pharmacognosy reviews 20110101

Title: Molecular determinants of magnolol targeting both RXRα and PPARγ.

Journal: PloS one 20110101

Title: The prospective role of plant products in radiotherapy of cancer: a current overview.

Journal: Frontiers in pharmacology 20110101

Title: Preparation and evaluation of poly (caprolactone fumarate) nanoparticles containing doxorubicin HCI.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: Neurotrophic activity of obovatol on the cultured embryonic rat neuronal cells by increase of neurotrophin release through activation of ERK pathway.

Journal: European journal of pharmacology 20101215

Title: Honokiol: an effective inhibitor of high-glucose-induced upregulation of inflammatory cytokine production in human renal mesangial cells.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201

Title: Synthesis, structural and in vitro studies of well-dispersed monomethoxy-poly(ethylene glycol)-honokiol conjugate micelles.

Journal: Biomedical materials (Bristol, England) 20101201

Title: A novel drug and gene co-delivery system based on Poly(epsilon-caprolactone)-Poly(ethylene glycol)-Poly(epsilon-caprolactone) grafted polyethyleneimine micelle.

Journal: Journal of nanoscience and nanotechnology 20101201

Title: Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation.

Journal: Carcinogenesis 20101101

Title: Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20101101

Title: [Variation of phenolic compound contents of Magnolia officinalis at different levels].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101

Title: Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells.

Journal: Phytotherapy research : PTR 20101001

Title: Separation of honokiol and magnolol by intermittent counter-current extraction.

Journal: Journal of chromatography. A 20100917

Title: Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders.

Journal: Molecules (Basel, Switzerland) 20100916

Title: The synergy of honokiol and fluconazole against clinical isolates of azole-resistant Candida albicans.

Journal: Letters in applied microbiology 20100901

Title: Substituted dineolignans from Magnolia garrettii.

Journal: Journal of natural products 20100827

Title: Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor.

Journal: Journal of natural products 20100827

Title: Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals.

Journal: British journal of pharmacology 20100801

Title: Characterization of neurotoxic effects of NMDA and the novel neuroprotection by phytopolyphenols in mice.

Journal: Behavioral neuroscience 20100801

Title: Hydrophobic ionic liquid-based ultrasound-assisted extraction of magnolol and honokiol from cortex Magnoliae officinalis.

Journal: Journal of separation science 20100701

Title: [Effects of primary processing on quality of cortex Magnolia officinalis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701

Title: Co-delivery honokiol and doxorubicin in MPEG-PLA nanoparticles.

Journal: Journal of nanoscience and nanotechnology 20100701

Title: Honokiol induces paraptosis and apoptosis and exhibits schedule-dependent synergy in combination with imatinib in human leukemia cells.

Journal: Toxicology mechanisms and methods 20100601

Title: Peroxyl radical scavenging capacity of extracts and isolated components from selected medicinal plants.

Journal: Archives of pharmacal research 20100601

Title: Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization.

Journal: Nanotechnology 20100528

Title: Purification of honokiol derivatives from one-pot synthesis by high-performance counter-current chromatography.

Journal: Journal of chromatography. A 20100514

Title: Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress.

Journal: Cancer letters 20100501

Title: Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100501

Title: Polymeric matrix for drug delivery: honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel.

Journal: Journal of biomedical materials research. Part A 20100401

Title: Honokiol inhibits HepG2 migration via down-regulation of IQGAP1 expression discovered by a quantitative pharmaceutical proteomic analysis.

Journal: Proteomics 20100401

Title: A novel transdermal honokiol formulation based on Pluronic F127 copolymer.

Journal: Drug delivery 20100401

Title: Anti-inflammatory bioactivities of honokiol through inhibition of protein kinase C, mitogen-activated protein kinase, and the NF-kappaB pathway to reduce LPS-induced TNFalpha and NO expression.

Journal: Journal of agricultural and food chemistry 20100324

Title: Chemopreventive effects of honokiol on UVB-induced skin cancer development.

Journal: Anticancer research 20100301

Title: Preparation of MPEG-PLA nanoparticle for honokiol delivery in vitro.

Journal: International journal of pharmaceutics 20100215

Title: Micronization of magnolia bark extract with enhanced dissolution behavior by rapid expansion of supercritical solution.

Journal: Chemical & pharmaceutical bulletin 20100201

Title: Honokiol and magnolol production by in vitro micropropagated plants of Magnolia dealbata, an endangered endemic Mexican species.

Journal: Natural product communications 20100201

Title: Quality assurance for Chinese herbal formulae: standardization of IBS-20, a 20-herb preparation.

Journal: Chinese medicine 20100101

Title: Effects of chronic treatment with honokiol in spontaneously hypertensive rats.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Honokiol inhibits osteoclast differentiation and function in vitro.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Synthesis and microbiological evaluation of honokiol derivatives as new antimicrobial agents.

Journal: Archives of pharmacal research 20100101

Title: Downregulated expression of HSP27 in human low-grade glioma tissues discovered by a quantitative proteomic analysis.

Journal: Proteome science 20100101

Title: Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin- resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy.

Journal: Journal of biological regulators and homeostatic agents 20100101

Title: Stem cell-based neuroprotective and neurorestorative strategies.

Journal: International journal of molecular sciences 20100101

Title: Honokiol increases ABCA1 expression level by activating retinoid X receptor beta.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Quasi-drugs developed in Japan for the prevention or treatment of hyperpigmentary disorders.

Journal: International journal of molecular sciences 20100101

Title: Honokiol inhibits the progression of collagen-induced arthritis by reducing levels of pro-inflammatory cytokines and matrix metalloproteinases and blocking oxidative tissue damage.

Journal: Journal of pharmacological sciences 20100101

Title: A Validated RP HPLC-PAD Method for the Determination of Hederacoside C in Ivy-Thyme Cough Syrup.

Journal: International journal of analytical chemistry 20100101

Title: Investigation of endocytosis and cytotoxicity of poly-d, l-lactide-poly(ethylene glycol) micro/nano-particles in osteoblast cells.

Journal: International journal of nanomedicine 20100101

Title: Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data.

Journal: Chinese medicine 20100101

Title: Pegylation of poly(γ-benzyl-L-glutamate) nanoparticles is efficient for avoiding mononuclear phagocyte system capture in rats.

Journal: International journal of nanomedicine 20100101

Title: Apoptosis induced by Magnolia Grandiflora extract in chlorambucil-resistant B-chronic lymphocytic leukemia cells.

Journal: Journal of cancer research and therapeutics 20100101

Title: Honokiol nanoparticles in thermosensitive hydrogel: therapeutic effects on malignant pleural effusion.

Journal: ACS nano 20091222

Title: Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice.

Journal: Brain research 20091211

Title: Neurite outgrowth effect of 4-O-methylhonokiol by induction of neurotrophic factors through ERK activation.

Journal: Neurochemical research 20091201

Title: Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis.

Journal: Biochemical and biophysical research communications 20091106

Title: [Effects of tree ages and geographic area on quality of bark of Magnolia officinalis and M. officinalis var. biloba].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091001

Title: Inhibitory effects of honokiol on LPS and PMA-induced cellular responses of macrophages and monocytes.

Journal: BMB reports 20090930

Title: Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20090901

Title: Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles.

Journal: Pharmaceutical research 20090901

Title: Improved therapeutic efficacy against murine carcinoma by combining honokiol with gene therapy of PNAS-4, a novel pro-apoptotic gene.

Journal: Cancer science 20090901

Title: Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats.

Journal: Archives of pharmacal research 20090901

Title: Semi-synthesis and anti-proliferative activity evaluation of novel analogues of Honokiol.

Journal: Bioorganic & medicinal chemistry letters 20090815

Title: Anti-inflammatory effect of 4-O-methylhonokiol, compound isolated from Magnolia officinalis through inhibition of NF-kappaB [corrected].

Journal: Chemico-biological interactions 20090814

Title: A novel composite drug delivery system: honokiol nanoparticles in thermosensitive hydrogel based on chitosan.

Journal: Journal of nanoscience and nanotechnology 20090801

Title: Novel composite drug delivery system for honokiol delivery: self-assembled poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) micelles in thermosensitive poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) hydrogel.

Journal: The journal of physical chemistry. B 20090730

Title: Simultaneous determination of the 10 major components of Da-Cheng-Qi decoction in dog plasma by liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Title: Antineoplastic effects of Magnoliae officinalis in tumours other than hepatomas.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20090701

Title: Protective effect of the ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on scopolamine-induced memory impairment and the inhibition of acetylcholinesterase activity.

Journal: Journal of natural medicines 20090701

Title: Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation.

Journal: Bioorganic & medicinal chemistry 20090701

Title: Production of honokiol and magnolol in suspension cultures of Magnolia dealbata Zucc.

Journal: Natural product communications 20090701

Title: Reactive oxygen species production and Bax/Bcl-2 regulation in honokiol-induced apoptosis in human hepatocellular carcinoma SMMC-7721 cells.

Journal: Environmental toxicology and pharmacology 20090701

Title: Poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) (PCL-PEG-PCL) nanoparticles for honokiol delivery in vitro.

Journal: International journal of pharmaceutics 20090622

Title: Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090615

Title: Liposomal honokiol inhibits VEGF-D-induced lymphangiogenesis and metastasis in xenograft tumor model.

Journal: International journal of cancer 20090601

Title: Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts.

Journal: Cardiovascular research 20090601

Title: Effects of neolignans from the stem bark of Magnolia obovata on plant pathogenic fungi.

Journal: Journal of applied microbiology 20090601

Title: Effects of mixed herbal extracts from parched Puerariae radix, gingered Magnoliae cortex, Glycyrrhizae radix and Euphorbiae radix (KIOM-79) on cardiac ion channels and action potentials.

Journal: Journal of Korean medical science 20090601

Title: Honokiol protects rats against eccentric exercise-induced skeletal muscle damage by inhibiting NF-kappaB induced oxidative stress and inflammation.

Journal: European journal of pharmacology 20090521

Title: Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells.

Journal: Cancer letters 20090518

Title: Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol.

Journal: Antioxidants & redox signaling 20090501

Title: Honokiol, a multifunctional antiangiogenic and antitumor agent.

Journal: Antioxidants & redox signaling 20090501

Title: [Micronization of magnolia bark extract by RESS as well as dissolution and pharmacokinetics evaluation].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090501

Title: Neolignans from North American Magnolia species with cyclooxygenase 2 inhibitory activity.

Journal: Inflammopharmacology 20090401

Title: Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes.

Journal: Toxicology and applied pharmacology 20090401

Title: Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c.

Journal: Journal of pharmacological sciences 20090401

Title: Preparation of honokiol-loaded chitosan microparticles via spray-drying method intended for pulmonary delivery.

Journal: Drug delivery 20090401

Title: Self-assembled honokiol-loaded micelles based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) copolymer.

Journal: International journal of pharmaceutics 20090318

Title: Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography.

Journal: Analytica chimica acta 20090202

Title: Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.

Journal: Nature chemical biology 20090201

Title: Simultaneous determination of 18alpha- and 18beta-glycyrrhetic acid in human plasma by LC-ESI-MS and its application to pharmacokinetics.

Journal: Biomedical chromatography : BMC 20090101

Title: Phenolic constituents from the stem bark of Magnolia officinalis.

Journal: Journal of natural products 20090101

Title: Combined xanthorrhizol-curcumin exhibits synergistic growth inhibitory activity via apoptosis induction in human breast cancer cells MDA-MB-231.

Journal: Cancer cell international 20090101

Title: In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) copolymer.

Journal: BMC biotechnology 20090101

Title: [Simultaneous determination of seven effective component in Houpuwenzhong capsules using high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20090101

Title: Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20090101

Title: Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain.

Journal: Journal of biomedical science 20090101

Title: Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity.

Journal: Experimental & molecular medicine 20081231

Title: Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection.

Journal: Journal of pharmaceutical and biomedical analysis 20081215

Title: Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2).

Journal: Liver international : official journal of the International Association for the Study of the Liver 20081201

Title: Mechanisms underlying the honokiol inhibition of evoked glutamate release from glutamatergic nerve terminals of the rat cerebral cortex.

Journal: Synapse (New York, N.Y.) 20081201

Title: LC-MS/MS method for the determination of cynandione A in rat plasma and tissues.

Journal: Biomedical chromatography : BMC 20081001

Title: Obovatol inhibits colorectal cancer growth by inhibiting tumor cell proliferation and inducing apoptosis.

Journal: Bioorganic & medicinal chemistry 20080915

Title: Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.

Journal: European journal of pharmacology 20080904

Title: Liposomal honokiol, a promising agent for treatment of cisplatin-resistant human ovarian cancer.

Journal: Journal of cancer research and clinical oncology 20080901

Title: Honokiol, a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20080901

Title: Honokiol is a potent scavenger of superoxide and peroxyl radicals.

Journal: Biochemical pharmacology 20080901

Title: [Effects of storage time on magnolol and honokiol contents in bark of Magnolia officinalis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Title: Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models.

Journal: Phytotherapy research : PTR 20080801

Title: Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.

Journal: Journal of pharmaceutical and biomedical analysis 20080715

Title: A novel injectable local hydrophobic drug delivery system: Biodegradable nanoparticles in thermo-sensitive hydrogel.

Journal: International journal of pharmaceutics 20080709

Title: Preparation and characterization of honokiol nanoparticles.

Journal: Journal of materials science. Materials in medicine 20080701

Title: Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080701

Title: The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.

Journal: Molecular cancer therapeutics 20080701

Title: [Effects of honokiol on proliferation and apoptosis of human cervical carcinoma cell line Hela in vitro].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080701

Title: Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis.

Journal: Free radical biology & medicine 20080615

Title: Differential proteomic analysis of HeLa cells treated with Honokiol using a quantitative proteomic strategy.

Journal: Amino acids 20080601

Title: Enhanced effects of xanthohumol plus honokiol on apoptosis in 3T3-L1 adipocytes.

Journal: Obesity (Silver Spring, Md.) 20080601

Title: Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080401

Title: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.

Journal: European journal of pharmacology 20080317

Title: Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.

Journal: The Journal of investigative dermatology 20080301

Title: Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells.

Journal: Bioscience, biotechnology, and biochemistry 20080301

Title: Magnolol and honokiol account for the anti-spasmodic effect of Magnolia officinalis in isolated guinea pig ileum.

Journal: Planta medica 20080301

Title: Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080215

Title: [Phenols in seedling cortex of Magnolia officinalis from Enshi].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080201

Title: [Pharmacokinetics of honokiol in rat after oral administration of Cortex of Magnolia officinalis and its compound preparation Houpu Sanwu Decoction].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080201

Title: Preparative purification of anti-tumor derivatives of honokiol by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20080118

Title: Enhancement of therapeutic effectiveness by combining liposomal honokiol with cisplatin in ovarian carcinoma.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101

Title: Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression.

Journal: Acta pharmacologica Sinica 20080101

Title: Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial.

Journal: Nutrition journal 20080101

Title: Simultaneous determination of eight major bioactive compounds in Dachengqi Tang (DT) by high-performance liquid chromatography.

Journal: Chinese medicine 20080101

Title: JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.

Journal: Journal of inflammation (London, England) 20080101

Title: Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model.

Journal: BMC cancer 20080101

Title: Antimicrobial and antioxidant activities of Cortex Magnoliae Officinalis and some other medicinal plants commonly used in South-East Asia.

Journal: Chinese medicine 20080101

Title: Evaluation of the in vitro and in vivo genotoxicity of magnolia bark extract.

Journal: Regulatory toxicology and pharmacology : RTP 20071201

Title: Compressed mints and chewing gum containing magnolia bark extract are effective against bacteria responsible for oral malodor.

Journal: Journal of agricultural and food chemistry 20071114

Title: Magnolol and honokiol: inhibitors against mouse passive cutaneous anaphylaxis reaction and scratching behaviors.

Journal: Biological & pharmaceutical bulletin 20071101

Title: Protective action of honokiol, administered orally, against oxidative stress in brain of mice challenged with NMDA.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20071001

Title: Cytotoxic lignans from the stem bark of Magnolia officinalis.

Journal: Journal of natural products 20071001

Title: Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity.

Journal: Molecular cancer therapeutics 20071001

Title: Effects of honokiol and magnolol on acute and inflammatory pain models in mice.

Journal: Life sciences 20070908

Title: Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.

Journal: Journal of medicinal chemistry 20070823

Title: Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol.

Journal: Bioorganic & medicinal chemistry letters 20070815

Title: Honokiol, a neuroprotectant against mouse cerebral ischaemia, mediated by preserving Na+, K+-ATPase activity and mitochondrial functions.

Journal: Basic & clinical pharmacology & toxicology 20070801

Title: Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070715

Title: Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

Title: Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest.

Journal: International journal of oncology 20070601

Title: [Effects of the active compounds of M. officinalis on cariogenic bacteria].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070601

Title: Honokiol induces a necrotic cell death through the mitochondrial permeability transition pore.

Journal: Cancer research 20070515

Title: Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells.

Journal: Cancer 20070401

Title: Rapid purification and scale-up of honokiol and magnolol using high-capacity high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20070223

Title: Analysis of magnolol and honokiol in biological fluids by capillary zone electrophoresis.

Journal: Journal of chromatography. A 20070223

Title: Honokiol up-regulates prostacyclin synthease protein expression and inhibits endothelial cell apoptosis.

Journal: European journal of pharmacology 20070105

Title: Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells.

Journal: Molecular cancer 20070101

Title: Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line.

Journal: BMC neuroscience 20070101

Title: Liquid chromatographic determination of honokiol and magnolol in hou po (Magnolia officinalis) as the raw herb and dried aqueous extract.

Journal: Journal of AOAC International 20070101

Title: Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.

Journal: PloS one 20070101

Title: [Investigate into of effective constituent transference of herba Ephedrae and cortex Magnoliae officinalis in preparation course of Shujin Kechuan capsule].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

Title: Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol.

Journal: Cancer letters 20061118

Title: Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061101

Title: Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells.

Journal: FEBS letters 20061002

Title: Simultaneous determination of honokiol and magnolol in Magnolia officinalis by liquid chromatography with tandem mass spectrometric detection.

Journal: Biomedical chromatography : BMC 20061001

Title: [Evaluation of antioxidant activity of Radix Linderae and other two Chinese drugs using TLC-bioautography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061001

Title: [Optimization of preparative technique for banxia-houpu effervescent tablets by orthogonal design].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20061001

Title: Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.

Journal: Molecular cancer research : MCR 20060901

Title: Honokiol, a small molecular weight natural product, alleviates experimental mesangial proliferative glomerulonephritis.

Journal: Kidney international 20060801

Title: Carbon nanotube/poly(methyl methacrylate) composite electrode for capillary electrophoretic measurement of honokiol and magnolol in Cortex Magnoliae Officinalis.

Journal: Electrophoresis 20060801

Title: Neuropharmacological effects of an ethanol extract of the Magnolia dealbata Zucc. leaves in mice.

Journal: Journal of ethnopharmacology 20060630

Title: Determination of honokiol and magnolol in cortex Magnoliae Officinalis by capillary electrophoresis with electrochemical detection.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: Facile purification of honokiol and its antiviral and cytotoxic properties.

Journal: Journal of medicinal chemistry 20060601

Title: Honokiol reduces oxidative stress, c-jun-NH2-terminal kinase phosphorylation and protects against glycochenodeoxycholic acid-induced apoptosis in primary cultured rat hepatocytes.

Journal: Planta medica 20060601

Title: Protective effects of honokiol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells.

Journal: Chemico-biological interactions 20060515

Title: Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage.

Journal: European journal of pharmacology 20060510

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Separation and determination of honokiol and magnolol in herbal medicines by flow injection-capillary electrophoresis.

Journal: Analytical and bioanalytical chemistry 20060401

Title: A comparative study of upright counter-current chromatography and high-performance liquid chromatograpohy for preparative isolation and purification ofphenolic compounds from Magnoliae officinalis.

Journal: Journal of separation science 20060201

Title: Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1.

Journal: Current oncology (Toronto, Ont.) 20060201

Title: Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada.

Journal: Journal of ethnobiology and ethnomedicine 20060101

Title: Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.

Journal: Biochemical pharmacology 20051115

Title: Honokiol protects against carbon tetrachloride induced liver damage in the rat.

Journal: Phytotherapy research : PTR 20051101

Title: Prokinetic effect of a Kampo medicine, Hange-koboku-to (Banxia-houpo-tang), on patients with functional dyspepsia.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20051101

Title: Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis.

Journal: Blood 20050901

Title: Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.

Journal: Neuropharmacology 20050901

Title: Honokiol inhibits arterial thrombosis through endothelial cell protection and stimulation of prostacyclin.

Journal: Acta pharmacologica Sinica 20050901

Title: Anxiolytic agent, dihydrohonokiol-B, recovers amyloid beta protein-induced neurotoxicity in cultured rat hippocampal neurons.

Journal: Neuroscience letters 20050801

Title: Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement.

Journal: World journal of gastroenterology 20050728

Title: The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.

Journal: Blood 20050715

Title: [Studies on HPLC chromatogram of phenolic constituents of Cortex Magnoliae Officinalis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050701

Title: Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2).

Journal: European journal of pharmacology 20050601

Title: Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-kappaB activation signaling.

Journal: Planta medica 20050401

Title: Determination of honokiol and magnolol by micro HPLC with electrochemical detection and its application to the distribution analysis in branches and leaves of Magnolia obovata.

Journal: Chemical & pharmaceutical bulletin 20050301

Title: Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid.

Journal: The international journal of biochemistry & cell biology 20050201

Title: Cytotoxic neolignans: an SAR study.

Journal: Bioorganic & medicinal chemistry letters 20050103

Title: Honokiol induces apoptosis via cytochrome c release and caspase activation in activated rat hepatic stellate cells in vitro.

Journal: Planta medica 20050101

Title: Anti-arrhythmic effects of herbal medicine.

Journal: Indian heart journal 20050101

Title: Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells.

Journal: BMC cancer 20050101

Title: Honokiol: a potent chemotherapy candidate for human colorectal carcinoma.

Journal: World journal of gastroenterology 20041201

Title: In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp.

Journal: European journal of pharmacology 20040802

Title: Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO.

Journal: World journal of gastroenterology 20040801

Title: Isolation and purification of honokiol and magnolol from cortex Magnoliae officinalis by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20040521

Title: Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan.

Journal: Bioorganic & medicinal chemistry letters 20040517

Title: Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones.

Journal: Journal of ethnopharmacology 20040401

Title: Antimicrobial and cytotoxic activities of neolignans from Magnolia officinalis.

Journal: Chemistry & biodiversity 20040301

Title: [Pharmacokinetics of honokiol in rats].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20040201

Title: Effects of Magnolol and Honokiol on the activities of streptococcal glucosyltransferases both in solution and adsorbed on an experimental pellicle.

Journal: Letters in applied microbiology 20040101

Title: Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production.

Journal: Brain research 20031205

Title: The mechanism of honokiol-induced and magnolol-induced inhibition on muscle contraction and Ca2+ mobilization in rat uterus.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031001

Title: Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo.

Journal: The Journal of biological chemistry 20030912

Title: The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production.

Journal: European journal of pharmacology 20030815

Title: Honokiol and magnolol induce Ca2+ mobilization in rat cortical neurons and human neuroblastoma SH-SY5Y cells.

Journal: European journal of pharmacology 20030808

Title: Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea.

Journal: Planta medica 20030601

Title: Honokiol ameliorates cerebral infarction from ischemia-reperfusion injury in rats.

Journal: Planta medica 20030201

Title: High-performance liquid chromatographic method for simultaneous determination of honokiol and magnolol in rat plasma.

Journal: Talanta 20030102

Title: Protective effects of honokiol and magnolol on tertiary butyl hydroperoxide- or D-galactosamine-induced toxicity in rat primary hepatocytes.

Journal: Planta medica 20030101

Title: [Study on HPLC-FPS of cortex magnoliae officinalis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020901

Title: Anti-platelet effect of the constituents isolated from the barks and fruits of Magnolia obovata.

Journal: Archives of pharmacal research 20020601

Title: Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells.

Journal: Biochemical pharmacology 20020501

Title: Neurotrophic activity of honokiol on the cultures of fetal rat cortical neurons.

Journal: Bioorganic & medicinal chemistry letters 20020422

Title: [Quality evaluation and utilization of germplasm resources of Magnolia officinalis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020201

Title: Inhibitory effect of magnolol and honokiol from Magnolia obovata on human fibrosarcoma HT-1080. Invasiveness in vitro.

Journal: Planta medica 20011101

Title: Effects of the extract of the bark of Magnolia obovata and its biphenolic constituents magnolol and honokiol on histamine release from peritoneal mast cells in rats.

Journal: Planta medica 20011101

Title: An anxiolytic agent, dihydrohonokiol-B, inhibits ammonia-induced increases in the intracellular Cl(-) of cultured rat hippocampal neurons via GABA(c) receptors.

Journal: Neuroscience letters 20011019

Title: Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro.

Journal: Pharmacology 20010701

Title: Effects of constituents from the bark of Magnolia obovata on nitric oxide production in lipopolysaccharide-activated macrophages.

Journal: Chemical & pharmaceutical bulletin 20010601

Title: Antimicrobial activity of honokiol and magnolol isolated from Magnolia officinalis.

Journal: Phytotherapy research : PTR 20010301

Title: Antifungal activity of magnolol and honokiol.

Journal: Archives of pharmacal research 20000201

Title: Myocardial protective effect of honokiol: an active component in Magnolia officinalis.

Journal: Planta medica 19961201

Title: Chang KH, et al. Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells. Oncol Lett. 2013 Nov;6(5):1435-1438.

Title: Godugu C, et al. Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC). Colloids Surf B Biointerfaces. 2017 Jan 23;153:208-219

Title: Lee TY, et al. Honokiol as a specific collagen receptor glycoprotein VI antagonist on human platelets: Functional ex vivo and in vivo studies. Sci Rep. 2017 Jan 5;7:40002

Title: Zhai H, et al. Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2). Eur J Pharmacol. 2005 Jun 1;516(2):112-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:35354-74-6 Molecular Formula|35354-74-6 MDL|35354-74-6 SMILES|35354-74-6 2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol