Home Amines 1036380-75-2
1036380-75-2,MFCD13689055
Catalog No.:AA003A1U

1036380-75-2 | Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate

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250mg
95%
in stock  
$62.00   $44.00
- +
1g
95%
in stock  
$84.00   $59.00
- +
5g
95%
in stock  
$351.00   $246.00
- +
10g
95%
in stock  
$549.00   $384.00
- +
25g
95%
in stock  
$1,353.00   $947.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003A1U
Chemical Name:
Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate
CAS Number:
1036380-75-2
Molecular Formula:
C10H8BrNO2S
Molecular Weight:
286.1450
MDL Number:
MFCD13689055
SMILES:
COC(=O)c1sc2c(c1N)cc(cc2)Br
Properties
Computed Properties
 
Complexity:
264  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.7  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartTao,Zhi-Fu;Hasvold,LisaA.;Leverson,JoelD.;Han,EdwardK.;Guan,Ran;Johnson,EricF.;Stoll,VincentS.;Stewart,KentD.;Stamper,Geoff;Soni,Nirupama;Bouska,JenniferJ.;Luo,Yan;Sowin,ThomasJ.;Lin,Nan-Horng;Giranda,VincentS.;Rosenberg,SaulH.;Penning,ThomasD.[JournalofMedicinalChemistry,2009,vol.52,#21,p.6621-6636]

[2]CurrentPatentAssignee:ABBVIEINC-US2008/161559,2008,A1Locationinpatent:Page/Pagecolumn8

[3]CurrentPatentAssignee:ABBOTTLABORATORIESINC-US2008/161578,2008,A1Locationinpatent:Page/Pagecolumn9

[4]Ekambaram,Ramesh;Enkvist,Erki;Vaasa,Angela;Kasari,Marje;Raidaru,Gerda;Knapp,Stefan;Uri,Asko[ChemMedChem,2013,vol.8,#6,p.909-913]

[1]CurrentPatentAssignee:ABBVIEINC-US2008/161559,2008,A1Locationinpatent:Page/Pagecolumn8

[2]CurrentPatentAssignee:ABBOTTLABORATORIESINC-US2008/161578,2008,A1Locationinpatent:Page/Pagecolumn9

[3]Locationinpatent:experimentalpartTao,Zhi-Fu;Hasvold,LisaA.;Leverson,JoelD.;Han,EdwardK.;Guan,Ran;Johnson,EricF.;Stoll,VincentS.;Stewart,KentD.;Stamper,Geoff;Soni,Nirupama;Bouska,JenniferJ.;Luo,Yan;Sowin,ThomasJ.;Lin,Nan-Horng;Giranda,VincentS.;Rosenberg,SaulH.;Penning,ThomasD.[JournalofMedicinalChemistry,2009,vol.52,#21,p.6621-6636]

[4]Bagley,MarkC.;Dwyer,JessicaE.;Molina,MariaD.Beltran;Rand,AlexanderW.;Rand,HayleyL.;Tomkinson,NicholasC.O.[OrganicandBiomolecularChemistry,2015,vol.13,#24,p.6814-6824]

[5]CurrentPatentAssignee:TAIWANJPHARMACEUTICALSCOLTD-WO2019/108943,2019,A1Locationinpatent:Paragraph0280;0281;0283;0284

[6]Locationinpatent:schemeortableSavall,BradM.;Gomez,Laurent;Chavez,Frank;Curtis,Michael;Meduna,StevenP.;Kearney,Aaron;Dunford,Paul;Cowden,Jeffery;Thurmond,RobinL.;Grice,Cheryl;Edwards,JamesP.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#21,p.6577-6581]

[7]Ekambaram,Ramesh;Enkvist,Erki;Vaasa,Angela;Kasari,Marje;Raidaru,Gerda;Knapp,Stefan;Uri,Asko[ChemMedChem,2013,vol.8,#6,p.909-913]

[1]Savall,BradM.;Gomez,Laurent;Chavez,Frank;Curtis,Michael;Meduna,StevenP.;Kearney,Aaron;Dunford,Paul;Cowden,Jeffery;Thurmond,RobinL.;Grice,Cheryl;Edwards,JamesP.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#21,p.6577-6581]

1036380-75-2   
C15H16BrN5S 

[1]Savall,BradM.;Gomez,Laurent;Chavez,Frank;Curtis,Michael;Meduna,StevenP.;Kearney,Aaron;Dunford,Paul;Cowden,Jeffery;Thurmond,RobinL.;Grice,Cheryl;Edwards,JamesP.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#21,p.6577-6581]

1036380-75-2   
(R)-8-Bromo-4-(3-methylamino-pyrrolidin-1-yl)-benzo4,5thieno3,2-dpyrimidin-2-ylamine 

[1]Savall,BradM.;Gomez,Laurent;Chavez,Frank;Curtis,Michael;Meduna,StevenP.;Kearney,Aaron;Dunford,Paul;Cowden,Jeffery;Thurmond,RobinL.;Grice,Cheryl;Edwards,JamesP.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#21,p.6577-6581]

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Tags:1036380-75-2 Molecular Formula|1036380-75-2 MDL|1036380-75-2 SMILES|1036380-75-2 Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate