Title: A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Journal: Nature 20150319
Title: Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.
Journal: Breast cancer research : BCR 20140101
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
Journal: Cancer research 20121101
Title: Novel pathway of centrosome amplification that does not require DNA lesions.
Journal: Cancer science 20120201
Title: Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
Journal: Nature structural & molecular biology 20101001
Title: Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051201
Title: Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Journal: Nature 20050414
Title: Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.
Journal: Oncogene 20040923
Title: Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040201
Title: Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
Journal: Journal of the National Cancer Institute 20040107
Title: Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
Journal: Cancer research 20030915
Title: Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.
Journal: Journal of medicinal chemistry 20030116
Title: Calabrese CR, et al. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J Natl Cancer Inst. 2004 Jan 7;96(1):56-67.
Title: Vazquez-Ortiz G, et al. Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells. Breast Cancer Res. 2014 Jun 24;16(3):R67.
Title: Smith LM, et al. The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks. Clin Cancer Res. 2005 Dec 1;11(23):8449-57.
