Name: Name:Fevipiprant
Brand: AABLOCKS
SKU: AA003AQK
Rating: 90 (10 reviews)

Catalog No.: AA003AQK

872365-14-5 | Fevipiprant

Pack Size： 1mg

Purity： 99+%

in stock

$31.00 $22.00

Pack Size： 5mg

Purity： 99+%

in stock

$76.00 $53.00

Pack Size： 25mg

Purity： 99+%

in stock

$200.00 $140.00

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Technical Information

Catalog Number: AA003AQK

Chemical Name: Fevipiprant

CAS Number: 872365-14-5

Molecular Formula: C19H17F3N2O4S

Molecular Weight: 426.4095

MDL Number: MFCD22548206

SMILES: OC(=O)Cc1c(C)n(c2c1cccn2)Cc1ccc(cc1C(F)(F)F)S(=O)(=O)C

Properties

Complexity: 709

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 29

Hydrogen Bond Acceptor Count: 8

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.8

Literature fold

Title: Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.

Journal: Molecular pharmacology20160501

Title: Brightling C, et al. The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant. Pulm Pharmacol Ther. 2021 Jun;68:102030.

Title: Lee HY, et al. Blockade of thymic stromal lymphopoietin and CRTH2 attenuates airway inflammation in a murine model of allergic asthma. Korean J Intern Med. 2020 May;35(3):619-629.

Title: Weintraub NL, et al. Role of prostaglandin D2 receptors in the pathogenesis of abdominal aortic aneurysm formation. Clin Sci (Lond). 2022 Mar 18;136(5):309-321.

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