Home Amines 57734-57-3
57734-57-3,MFCD00462218
Catalog No.:AA003BL7

57734-57-3 | Pyrrolidin-2-ylmethanamine

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250mg
98%
in stock  
$128.00   $90.00
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1g
98%
in stock  
$278.00   $195.00
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5g
98%
in stock  
$826.00   $578.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003BL7
Chemical Name:
Pyrrolidin-2-ylmethanamine
CAS Number:
57734-57-3
Molecular Formula:
C5H12N2
Molecular Weight:
100.1622
MDL Number:
MFCD00462218
SMILES:
NCC1CCCN1
Properties
Properties
 
BP:
152.9°C at 760 mmHg  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
54  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-0.6  

Downstream Synthesis Route

[1]JournalofPharmaceuticalSciences,1991,vol.80,p.837-842

[2]EuropeanJournalofMedicinalChemistry,2009,vol.44,p.2807-2814

[3]TetrahedronLetters,2012,vol.53,p.3541-3545

[4]CuihuaXuebao/ChineseJournalofCatalysis,2016,vol.37,p.1227-1234

[5]Patent:WO2007/127505,2007,A2.Locationinpatent:Page/Pagecolumn81-82

[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1983,vol.22,p.664-668

[1]Putochin[ZhurnalRusskagoFiziko-KhimicheskagoObshchestva,1930,vol.62,p.2209,2212][ChemischesZentralblatt,1931,vol.102,#II,p.441]

[1]Patent:WO2006/116764,2006,A1.Locationinpatent:Page/Pagecolumn136

[1]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.1023-1026

Literature

Title: Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr=N-dimethyl-2(R)-aminomethylpyrrolidine).

Journal: European journal of medicinal chemistry 20090701

Title: Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.

Journal: Journal of medicinal chemistry 20050324

Title: Studies on adenosine A2a receptor antagonists: comparison of three core heterocycles.

Journal: Bioorganic & medicinal chemistry letters 20041004

Title: Structures of platinum(II) complexes of 2-aminomethylaziridine and S-2-aminomethylazetidine and correlation of anticancer activities of (2-aminomethylazacycloalkane)platinum(II) complexes with the geometry of the chelate rings formed with platinum(II).

Journal: Chemical & pharmaceutical bulletin 20040101

Title: Conformation of 2-aminomethylpyrrolidine and 2-aminomethylpiperidine in ternary platinum(II) complexes: regulation of conformation of the diamine by the coexisting ligand.

Journal: Chemical & pharmaceutical bulletin 20031001

Title: Synthesis and D(2)-like binding affinity of new derivatives of N-(1-ethyl-2-pyrrolidinylmethyl)-4,5-dihydro-1H-benzo[g]indole-3-carboxamide and related 4H-[1]benzothiopyrano[4,3-b]pyrrole and 5,6-dihydro-4H-benzo[6,7]cyclohepta[b]pyrrole-3-carboxamide analogues.

Journal: Bioorganic & medicinal chemistry 20020801

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