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1066-51-9,MFCD00008105
Catalog No.:AA003BWN

1066-51-9 | (Aminomethyl)phosphonic acid

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250mg
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1g
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5g
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$83.00   $58.00
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10g
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25g
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003BWN
Chemical Name:
(Aminomethyl)phosphonic acid
CAS Number:
1066-51-9
Molecular Formula:
CH6NO3P
Molecular Weight:
111.0370
MDL Number:
MFCD00008105
SMILES:
NCP(=O)(O)O
NSC Number:
30076
Properties
Properties
 
BP:
358°C at 760 mmHg  
Form:
Solid  
MP:
300 °C  
Solubility:
water: soluble50mg/mL, clear, colorless  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
74.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
-4.7  

Downstream Synthesis Route
64-67-5    1066-51-9    67910-53-6   
triethylammoniomethylphosphonate 

[1]IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1951,p.620,623    Chem.Abstr.,1952,p.7996

[1]JournaloftheAmericanChemicalSociety,1953,vol.75,p.5278

[1],1952,vol.2,p.12;dtsch.Ausg.S.15

[2]LiebigsAnnalenderChemie,1988,p.861-868

[1]LiebigsAnnalenderChemie,1990,p.331-334

[1]JournaloftheAmericanChemicalSociety,1987,vol.109,p.6758-6764

Literature

Title: Aminomethylphosphonic acid and methoxyacetic acid induce apoptosis in prostate cancer cells.

Journal: International journal of molecular sciences 20150501

Title: Utilization of glyphosate as phosphate source: biochemistry and genetics of bacterial carbon-phosphorus lyase.

Journal: Microbiology and molecular biology reviews : MMBR 20140301

Title: Glyphosate and AMPA inhibit cancer cell growth through inhibiting intracellular glycine synthesis.

Journal: Drug design, development and therapy 20130101

Title: Development and application of a liquid chromatography-mass spectrometry method to evaluate the glyphosate and aminomethylphosphonic acid dissipation in maize plants after foliar treatment.

Journal: Journal of agricultural and food chemistry 20120425

Title: Occurrence of glyphosate and acidic herbicides in select urban rivers and streams in Canada, 2007.

Journal: Environmental science and pollution research international 20120301

Title: Pool of resistance mechanisms to glyphosate in Digitaria insularis.

Journal: Journal of agricultural and food chemistry 20120118

Title: Fate and transport of glyphosate and aminomethylphosphonic acid in surface waters of agricultural basins.

Journal: Pest management science 20120101

Title: Isoflavones-Enriched Soy Protein Prevents CCL(4)-Induced Hepatotoxicity in Rats.

Journal: ISRN pharmacology 20120101

Title: Dissipation of glyphosate and aminomethylphosphonic acid in water and sediment of two Canadian prairie wetlands.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

Title: [Determination of glyphosate and aminomethylphosphonic acid in rice using hydrophilic interaction chromatography-tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20120101

Title: Catabolism and detoxification of 1-aminoalkylphosphonic acids: N-acetylation by the phnO gene product.

Journal: PloS one 20120101

Title: Study of liquid chromatography/electrospray ionization mass spectrometry matrix effect on the example of glyphosate analysis from cereals.

Journal: Rapid communications in mass spectrometry : RCM 20111115

Title: Electric field-driven extraction of lipophilic anions across a carrier-mediated polymer inclusion membrane.

Journal: Analytical chemistry 20111001

Title: Direct aqueous determination of glyphosate and related compounds by liquid chromatography/tandem mass spectrometry using reversed-phase and weak anion-exchange mixed-mode column.

Journal: Journal of chromatography. A 20110819

Title: Rapid determination of glyphosate, glufosinate, bialaphos, and their major metabolites in serum by liquid chromatography-tandem mass spectrometry using hydrophilic interaction chromatography.

Journal: Journal of chromatography. A 20110610

Title: Glyphosate degradation in glyphosate-resistant and -susceptible crops and weeds.

Journal: Journal of agricultural and food chemistry 20110608

Title: New approaches to identification and activity estimation of glyphosate degradation enzymes.

Journal: Biochemistry. Biokhimiia 20110601

Title: Comparative studies on the retardation and reduction of glyphosate during subsurface passage.

Journal: Water research 20110501

Title: Physiological responses of glyphosate-resistant and glyphosate-sensitive soybean to aminomethylphosphonic acid, a metabolite of glyphosate.

Journal: Chemosphere 20110401

Title: Occurrence and fate of the herbicide glyphosate and its degradate aminomethylphosphonic acid in the atmosphere.

Journal: Environmental toxicology and chemistry 20110301

Title: Optimization of extraction procedure and chromatographic separation of glyphosate, glufosinate and aminomethylphosphonic acid in soil.

Journal: Analytical and bioanalytical chemistry 20110201

Title: Defined plant extracts can protect human cells against combined xenobiotic effects.

Journal: Journal of occupational medicine and toxicology (London, England) 20110101

Title: Laboratory and lysimeter studies of glyphosate and aminomethylphosphonic acid in a sand and a clay soil.

Journal: Journal of environmental quality 20110101

Title: Development and validation of a liquid chromatography-fluorescence-mass spectrometry method to measure glyphosate and aminomethylphosphonic acid in rat plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101201

Title: Comparative environmental impacts of glyphosate and conventional herbicides when used with glyphosate-tolerant and non-tolerant crops.

Journal: Environmental pollution (Barking, Essex : 1987) 20101001

Title: Charge density distribution in aminomethylphosphonic acid.

Journal: Acta crystallographica. Section B, Structural science 20101001

Title: Dynamic supported liquid membrane tip extraction of glyphosate and aminomethylphosphonic acid followed by capillary electrophoresis with contactless conductivity detection.

Journal: Journal of chromatography. A 20100910

Title: Impacts of mixtures of herbicides on molecular and physiological responses of the European flounder Platichthys flesus.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100901

Title: An amperometric method for the detection of amitrole, glyphosate and its aminomethyl-phosphonic acid metabolite in environmental waters using passive samplers.

Journal: Analytica chimica acta 20100824

Title: [Determination of glyphosate and aminomethylphosphonic acid in rice using liquid chromatography-tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20100801

Title: Effect of suppressor current intensity on the determination of glyphosate and aminomethylphosphonic acid by suppressed conductivity ion chromatography.

Journal: Journal of chromatography. A 20100528

Title: Enrichment and low-level determination of glyphosate, aminomethylphosphonic acid and glufosinate in drinking water after cleanup by cation exchange resin.

Journal: Journal of separation science 20100401

Title: Determination of glyphosate and its metabolites in plant material by reversed-polarity CE with indirect absorptiometric detection.

Journal: Electrophoresis 20100401

Title: Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines.

Journal: Journal of occupational medicine and toxicology (London, England) 20100101

Title: Degradation of 14C-glyphosate and aminomethylphosphonic acid (AMPA) in three agricultural soils.

Journal: Journal of environmental sciences (China) 20100101

Title: Effects of glyphosate-resistant crop cultivation on soil and water quality.

Journal: GM crops 20100101

Title: Microscale solid phase extraction of glyphosate and aminomethylphosphonic acid in water and guava fruit extract using alumina-coated iron oxide nanoparticles followed by capillary electrophoresis and electrochemiluminescence detection.

Journal: Journal of chromatography. A 20091204

Title: Toxicokinetics of glyphosate and its metabolite aminomethyl phosphonic acid in rats.

Journal: Toxicology letters 20091008

Title: Delayed degradation in soil of foliar herbicides glyphosate and sulcotrione previously absorbed by plants: consequences on herbicide fate and risk assessment.

Journal: Chemosphere 20091001

Title: Transfer of glyphosate and its degradate AMPA to surface waters through urban sewerage systems.

Journal: Chemosphere 20090901

Title: The occurrence of glyphosate, atrazine, and other pesticides in vernal pools and adjacent streams in Washington, DC, Maryland, Iowa, and Wyoming, 2005-2006.

Journal: Environmental monitoring and assessment 20090801

Title: Decontamination of aqueous glyphosate, (aminomethyl)phosphonic acid, and glufosinate solutions by electro-fenton-like process with Mn2+ as the catalyst.

Journal: Journal of agricultural and food chemistry 20090610

Title: Speciation of glyphosate, phosphate and aminomethylphosphonic acid in soil extracts by ion chromatography with inductively coupled plasma mass spectrometry with an octopole reaction system.

Journal: Talanta 20090515

Title: Constant pressure-assisted head-column field-amplified sample injection in combination with in-capillary derivatization for enhancing the sensitivity of capillary electrophoresis.

Journal: Journal of chromatography. A 20090515

Title: An alternative and fast method for determination of glyphosate and aminomethylphosphonic acid (AMPA) residues in soybean using liquid chromatography coupled with tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20090401

Title: Genotoxicity of AMPA, the environmental metabolite of glyphosate, assessed by the Comet assay and cytogenetic tests.

Journal: Ecotoxicology and environmental safety 20090301

Title: A measure of endosomal pH by flow cytometry in Dictyostelium.

Journal: BMC research notes 20090101

Title: SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.

Journal: PloS one 20090101

Title: Characterisation of Campylobacter jejuni genes potentially involved in phosphonate degradation.

Journal: Gut pathogens 20090101

Title: New approaches for determination of glyphosate and aminomethylphosphonic acid from different tea samples--prospects and limits of cleanup with molecularly imprinted polymer and titanium dioxide.

Journal: Journal of AOAC International 20090101

Title: Efficiency of a bagasse substrate in a biological bed system for the degradation of glyphosate, malathion and lambda-cyhalothrin under tropical climate conditions.

Journal: Pest management science 20081201

Title: Determination of glyphosate, glyphosate metabolites, and glufosinate in human serum by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115

Title: Rapid and direct determination of glyphosate and aminomethylphosphonic acid in water using anion-exchange chromatography with coulometric detection.

Journal: Journal of chromatography. A 20081024

Title: A theoretical study of medium effects on the structure of the glycine analogue aminomethylphosphonic acid.

Journal: Physical chemistry chemical physics : PCCP 20080928

Title: An ATR-FTIR study of different phosphonic acids in aqueous solution.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080701

Title: Ultratrace-level determination of glyphosate, aminomethylphosphonic acid and glufosinate in natural waters by solid-phase extraction followed by liquid chromatography-tandem mass spectrometry: performance tuning of derivatization, enrichment and detection.

Journal: Analytical and bioanalytical chemistry 20080701

Title: Fate and availability of glyphosate and AMPA in agricultural soil.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20080601

Title: Micro-scale membrane extraction of glyphosate and aminomethylphosphonic acid in water followed by high-performance liquid chromatography and post-column derivatization with fluorescence detector.

Journal: Journal of chromatography. A 20080502

Title: Determination of glyphosate and AMPA in surface and waste water using high-performance ion chromatography coupled to inductively coupled plasma dynamic reaction cell mass spectrometry (HPIC-ICP-DRC-MS).

Journal: Analytical and bioanalytical chemistry 20080501

Title: Occurrence of glyphosate in surface waters of Southern Ontario.

Journal: Bulletin of environmental contamination and toxicology 20080401

Title: Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.

Journal: Journal of agricultural and food chemistry 20080326

Title: Measurement and modelling of glyphosate fate compared with that of herbicides replaced as a result of the introduction of glyphosate-resistant oilseed rape.

Journal: Pest management science 20080301

Title: Longitudinal changes in microbial planktonic communities of a French river in relation to pesticide and nutrient inputs.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080218

Title: Analysis of glyphosate and aminomethylphosphonic acid by capillary electrophoresis with electrochemiluminescence detection.

Journal: Journal of chromatography. A 20080104

Title: Influence of complexation phenomena with multivalent cations on the analysis of glyphosate and aminomethyl phosphonic acid in water.

Journal: Journal of chromatography. A 20071221

Title: Surface-enhanced Raman spectroscopy for uranium detection and analysis in environmental samples.

Journal: Analytica chimica acta 20071212

Title: Concentrations and specific loads of glyphosate, diuron, atrazine, nonylphenol and metabolites thereof in French urban sewage sludge.

Journal: Chemosphere 20071101

Title: Photodegradation of glyphosate in the ferrioxalate system.

Journal: Journal of hazardous materials 20070905

Title: Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.

Journal: Nature chemical biology 20070801

Title: [Determination of glyphosate and aminomethylphosphonic acid residues in foods using high performance liquid chromatography-mass spectrometry/mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20070701

Title: Solid phase extraction of phosphorus-containing amino acid-type herbicides and their metabolites from human blood with titania for determination by capillary electrophoresis.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070601

Title: In-capillary derivatization and laser-induced fluorescence detection for the analysis of organophosphorus pesticides by micellar electrokinetic chromatography.

Journal: Journal of chromatography. A 20070518

Title: Glyphosate and AMPA analysis in sewage sludge by LC-ESI-MS/MS after FMOC derivatization on strong anion-exchange resin as solid support.

Journal: Analytical chemistry 20070515

Title: Re-evaluation of glyphosate determination in water by liquid chromatography coupled to electrospray tandem mass spectrometry.

Journal: Journal of chromatography. A 20061117

Title: Urban contributions of glyphosate and its degradate AMPA to streams in the United States.

Journal: The Science of the total environment 20060201

Title: Agricultural pesticide residues in farm ditches of the Lower Fraser Valley, British Columbia, Canada.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101

Title: Determination of glyphosate and phosphate in water by ion chromatography--inductively coupled plasma mass spectrometry detection.

Journal: Journal of chromatography. A 20051230

Title: Rapid and sensitive determination of phosphorus-containing amino acid herbicides in soil samples by capillary zone electrophoresis with diode laser-induced fluorescence detection.

Journal: Electrophoresis 20051201

Title: Oxidative degradation of glyphosate and aminomethylphosphonate by manganese oxide.

Journal: Environmental science & technology 20051201

Title: Determination of glyphosate and its metabolite aminomethylphosphonic acid in fruit juices using supported-liquid membrane preconcentration method with high-performance liquid chromatography and UV detection after derivatization with p-toluenesulphonyl chloride.

Journal: Journal of chromatography. A 20051104

Title: Matrix solid-phase dispersion extraction and determination by high-performance liquid chromatography with fluorescence detection of residues of glyphosate and aminomethylphosphonic acid in tomato fruit.

Journal: Journal of chromatography. A 20051104

Title: Efficacy and fate of glyphosate on Swedish railway embankments.

Journal: Pest management science 20050901

Title: Environmental fate of herbicides trifluralin, metazachlor, metamitron and sulcotrione compared with that of glyphosate, a substitute broad spectrum herbicide for different glyphosate-resistant crops.

Journal: Pest management science 20050901

Title: Residue determination of glyphosate, glufosinate and aminomethylphosphonic acid in water and soil samples by liquid chromatography coupled to electrospray tandem mass spectrometry.

Journal: Journal of chromatography. A 20050722

Title: Glyphosate immunosensor. Application for water and soil analysis.

Journal: Analytical chemistry 20050701

Title: Differential effects of glyphosate and roundup on human placental cells and aromatase.

Journal: Environmental health perspectives 20050601

Title: The potential of inductively coupled plasma-mass spectrometric detection for capillary electrophoretic analysis of pesticides.

Journal: Electrophoresis 20050401

Title: Photodegradation of phosphonates in water.

Journal: Chemosphere 20050401

Title: Switching of PET fluorescence signals induced by ligand exchange reactions of N-(9-anthrylmethyl)amine on Cu(II) complexes and its application to postcolumn detection of glyphosate.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050401

Title: Phosphonate catabolism by Campylobacter spp.

Journal: Archives of microbiology 20050201

Title: Aminomethylphosphonic acid and glyphosate adsorption onto goethite: a comparative study.

Journal: Environmental science & technology 20050115

Title: Simultaneous fluorimetric determination of glyphosate and its metabolite, aminomethylphosphonic acid, in water, previous derivatization with NBD-Cl and by partial least squares calibration (PLS).

Journal: Talanta 20050115

Title: Leaching of glyphosate and amino-methylphosphonic acid from Danish agricultural field sites.

Journal: Journal of environmental quality 20050101

Title: Analytical methods used in the United Kingdom Wildlife Incident Investigation Scheme for the detection of animal poisoning by pesticides.

Journal: Journal of AOAC International 20050101

Title: Health considerations regarding horizontal transfer of microbial transgenes present in genetically modified crops.

Journal: Journal of biomedicine & biotechnology 20050101

Title: Analysis of phosphorus herbicides by ion-pairing reversed-phase liquid chromatography coupled to inductively coupled plasma mass spectrometry with octapole reaction cell.

Journal: Journal of chromatography. A 20040924

Title: Aminomethylphosphonic acid, a metabolite of glyphosate, causes injury in glyphosate-treated, glyphosate-resistant soybean.

Journal: Journal of agricultural and food chemistry 20040811

Title: Simultaneous quantification of glyphosate, glufosinate, and their major metabolites in rice and soybean sprouts by gas chromatography with pulsed flame photometric detector.

Journal: Journal of agricultural and food chemistry 20040630

Title: Herbicide runoff along highways. 1. Field observations.

Journal: Environmental science & technology 20040615

Title: Preconcentration of the herbicide glyphosate and its metabolite AMPA by immobilised metal ion affinity chromatography (IMAC).

Journal: Journal of separation science 20040501

Title: Improved coupled-column liquid chromatographic method for the determination of glyphosate and aminomethylphosphonic acid residues in environmental waters.

Journal: Journal of chromatography. A 20040430

Title: Monitoring glyphosate residues in transgenic glyphosate-resistant soybean.

Journal: Pest management science 20040201

Title: Negative ion electrospray mass spectrometry of aminomethylphosphonic acid and glyphosate: elucidation of fragmentation mechanisms by multistage mass spectrometry incorporating in-source deuterium labelling.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Concentrations of glyphosate and AMPA in sediment following operational applications of Rodeo to control smooth cordgrass in Willapa Bay, Washington, USA.

Journal: Bulletin of environmental contamination and toxicology 20031101

Title: Effect of glyphosate on the microbial activity of two Brazilian soils.

Journal: Chemosphere 20030801

Title: Analysis of glyphosate and glufosinate by capillary electrophoresis-mass spectrometry utilising a sheathless microelectrospray interface.

Journal: Journal of chromatography. A 20030704

Title: Determination of the herbicide glyphosate and its metabolite in biological specimens by gas chromatography-mass spectrometry. A case of poisoning by roundup herbicide.

Journal: Journal of analytical toxicology 20030401

Title: Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.

Journal: Journal of agricultural and food chemistry 20030101

Title: Tandem mass spectrometric analysis of glyphosate, glufosinate, aminomethylphosphonic acid and methylphosphinicopropionic acid.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Analysis of glyphosate, glufosinate and aminomethylphosphonic acid by capillary electrophoresis with indirect fluorescence detection.

Journal: Journal of chromatography. A 20020614

Title: Analytical potential of fluorescein analogues for ultrasensitive determinations of phosphorus-containing amino acid herbicides by micellar electrokinetic chromatography with laser-induced fluorescence detection.

Journal: Electrophoresis 20020401

Title: Investigation of the herbicide glyphosate and the plant growth regulators chlormequat and mepiquat in cereals produced in Denmark.

Journal: Food additives and contaminants 20011001

Title: [Analysis of glyphosate and its metabolite, aminomethylphosphonic acid, in agricultural products by HPLC].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20011001

Title: Dynamics of glyphosate and aminomethylphosphonic acid in a forest soil in Galicia, north-west Spain.

Journal: The Science of the total environment 20010423

Title: Simultaneous determination of phosphorus-containing amino acid-herbicides by nonionic surfactant micellar electrokinetic chromatography with laser-induced fluorescence detection.

Journal: Electrophoresis 20010401

Title: Determination by glyphosate and aminomethylphosphonic acid in crops by capillary gas chromatography with mass-selective detection: collaborative study.

Journal: Journal of AOAC International 20010101

Title: New aminophosphonates with antioxidative activity.

Journal: Cellular & molecular biology letters 20010101

Title: Liquid chromatography/electrospray ionization/isotopic dilution mass spectrometry analysis of n-(phosphonomethyl) glycine and mass spectrometry analysis of aminomethyl phosphonic acid in environmental water and vegetation matrixes.

Journal: Journal of AOAC International 20010101

Title: Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.

Journal: Journal of medicinal chemistry 19860101

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