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694-83-7,MFCD00001491
Catalog No.:AA003DAM

694-83-7 | 1,2-Diaminocyclohexane

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  • Technical Information
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Technical Information
Catalog Number:
AA003DAM
Chemical Name:
1,2-Diaminocyclohexane
CAS Number:
694-83-7
Molecular Formula:
C6H14N2
Molecular Weight:
114.1888
MDL Number:
MFCD00001491
SMILES:
NC1CCCCC1N
UN Number:
2735
Properties
Properties
 
BP:
92-93 °C18 mm Hg(lit.)  
Form:
Liquid  
MP:
41-45 °C  
Refractive Index:
n20/D 1.49(lit.)  
Stability:
Air Sensitive  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
62.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Undefined Atom Stereocenter Count:
2  
XLogP3:
-0.3  

Literature

Title: Synthesis and antitubercular activity evaluation of novel unsymmetrical cyclohexane-1,2-diamine derivatives.

Journal: Archiv der Pharmazie 20121101

Title: Conversion of D-penicillaminato trinuclear to mononuclear palladium(II) structure by diamine ligands: remarkable enantioselectivity toward racemic 1,2-cyclohexanediamine.

Journal: Dalton transactions (Cambridge, England : 2003) 20121007

Title: Effects of electron configuration and coordination number on the vibrational circular dichroism spectra of metal complexes of trans-1,2-diaminocyclohexane.

Journal: Physical chemistry chemical physics : PCCP 20121005

Title: A new 'fully reduced' polyoxovanadate constructed from nanosized triangle-shaped [V(III)3V(IV)18P6O60(DACH)3]}9- cluster anions exhibiting ferrimagnetic interactions.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120917

Title: An efficient organocatalytic method for highly enantioselective Michael addition of malonates to enones catalyzed by readily accessible primary amine-thiourea.

Journal: Organic letters 20120817

Title: Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation.

Journal: Journal of the American Chemical Society 20120815

Title: Synthesis and photophysical properties of water-soluble sulfonato-Salen-type Schiff bases and their applications of fluorescence sensors for Cu2+ in water and living cells.

Journal: Analytica chimica acta 20120720

Title: Development of diamidophosphite ligands and their application to the palladium-catalyzed vinyl-substituted trimethylenemethane asymmetric [3 + 2] cycloaddition.

Journal: Journal of the American Chemical Society 20120718

Title: Metallomacrocycles as ligands: synthesis and characterisation of aluminium-bridged bisglyoximato complexes of palladium and iron.

Journal: Dalton transactions (Cambridge, England : 2003) 20120714

Title: Antitumor platinum(II) complexes of N-monoalkyl-1R, 2R-diaminocyclohexane derivatives with alkyl groups as hindrance.

Journal: Journal of inorganic biochemistry 20120701

Title: catena-Poly[[trans-bis-(cyclo-hexane-1,2-diamine-κ²N,N)cadmium]-μ-iodido-(diiodidocadmium)-μ-iodido].

Journal: Acta crystallographica. Section E, Structure reports online 20120701

Title: LEV-zeotype magnesium aluminophosphates with variable Mg/Al ratios.

Journal: Dalton transactions (Cambridge, England : 2003) 20120614

Title: Stereoselective UV sensing of 1,2-diaminocyclohexane isomers based on ligand displacement with a diacridylnaphthalene N,N'-dioxide scandium complex.

Journal: The Journal of organic chemistry 20120601

Title: 2-Amino-cyclo-hexan-1-aminium thio-cyanate.

Journal: Acta crystallographica. Section E, Structure reports online 20120601

Title: Diastereoselective imine-bond formation through complementary double-helix formation.

Journal: Journal of the American Chemical Society 20120502

Title: cis-[1,4-Bis(diphenyl-phosphan-yl)butane-κ(2)P,P']dichlorido(cyclo-hexane-1,2-diamine-κ(2)N,N')ruthenium(II) dichloro-methane monosolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20120430

Title: Influence of the solvent and metal center on supramolecular chirality induction with bisporphyrin tweezer receptors. Strong metal modulation of effective molarity values.

Journal: Inorganic chemistry 20120416

Title: Synthesis, in vitro cytotoxicity, and interaction with DNA of platinum(II) complexes with N-monocycloalkyl derivatives of 1R,2R-diaminocyclohexane as carrier ligands.

Journal: ChemMedChem 20120401

Title: {2-[(2-Amino-cyclo-hex-yl)imino-meth-yl]phenolato}dioxidovanadium(V).

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: trans-1,2-Diaminocyclohexane mesoporous silica for asymmetric catalysis: enhancement of chirality through confinement space by the plug effect.

Journal: Chemical communications (Cambridge, England) 20120325

Title: A wheel-shaped indium-telluride nanocluster [In18Te30(dach)6]6-: its formation and structure.

Journal: Inorganic chemistry 20120206

Title: Theoretical investigation on the chiral diamine-catalyzed epoxidation of cyclic enones: mechanism and effects of cocatalyst.

Journal: The journal of physical chemistry. A 20120202

Title: Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120201

Title: L type Ca²+ channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats.

Journal: Molecular pain 20120101

Title: Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC).

Journal: Journal of translational medicine 20120101

Title: Steric modifications tune the regioselectivity of the alkane oxidation catalyzed by non-heme iron complexes.

Journal: Inorganic chemistry 20111219

Title: Aza-crown macrocycles as chiral solvating agents for mandelic acid derivatives.

Journal: The Journal of organic chemistry 20111216

Title: Interactions of an asymmetric amine with a non-C2 symmetric Cu-salen complex: an EPR/ENDOR and HYSCORE investigation.

Journal: Physical chemistry chemical physics : PCCP 20111207

Title: cis-N,N-Bis(2-hy-droxy-benzyl-idene)cyclo-hexane-1,2-diamine.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Diethyl 4,4'-dihy-droxy-3,3'-{[(3aRS,7aRS)-2,3,3a,4,5,6,7,7a-octa-hydro-1H-1,3-benzimidazole-1,3-di-yl]bis-(methyl-ene)}dibenzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: New half sandwich-type Ru(II) coordination compounds characterized by the fac-Ru(dmso-S)3 fragment: influence of the face-capping group on the chemical behavior and in vitro anticancer activity.

Journal: Dalton transactions (Cambridge, England : 2003) 20111007

Title: Unsymmetric salen ligands bearing a Lewis base: intramolecularly cooperative catalysis for cyanosilylation of aldehydes.

Journal: Organic & biomolecular chemistry 20110921

Title: Enantioselective fluorescent recognition of mandelic acid by unsymmetrical salalen and salan sensors.

Journal: Organic & biomolecular chemistry 20110907

Title: Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Convenient, enantioselective hydrosilylation of imines in protic media catalyzed by a Zn-trianglamine complex.

Journal: Organic & biomolecular chemistry 20110521

Title: Effect of a dual drug-coated stent with abciximab and alpha-lipoic Acid in a porcine coronary restenosis model.

Journal: Korean circulation journal 20110501

Title: (±)-1,2-Bis(N'-benzoyl-thio-ureido)cyclo-hexa-ne.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: rac-Ethyl (2Z)-3-{2-[(Z)-4-eth-oxy-4-oxobut-2-en-2-yl-amino]-cyclo-hexyl-amino}-but-2-enoate.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: Chiral diaminopyrrolic receptors for selective recognition of mannosides, part 1: design, synthesis, and affinities of second-generation tripodal receptors.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110418

Title: Molecular origin for helical winding of fibrils formed by perfluorinated gelators.

Journal: Chemical communications (Cambridge, England) 20110407

Title: trans-Diaqua-bis-(cyclo-hexane-1,2-diamine)-zinc(II) dichloride.

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: A mechanistic approach for the DNA binding of chiral enantiomeric L- and D-tryptophan-derived metal complexes of 1,2-DACH: cleavage and antitumor activity.

Journal: Chirality 20110301

Title: (1R,2R)-2-(Pyridin-4-yl-methyl-amino)-cyclo-hexa-naminium chloride.

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: Asymmetric transfer hydrogenation of prochiral ketones in aqueous media with chiral water-soluble and heterogenized bifunctional catalysts of the RhCp*-type ligand.

Journal: Chirality 20110201

Title: Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting.

Journal: Science translational medicine 20110105

Title: Synthesis, characterization and biological evaluation of platinum(II) complexes with a chiral N-monosubstituted 1,2-cyclohexyldiamine derivative.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Effect of the structure of the diamine backbone of P-N-N-P ligands in iron(II) complexes on catalytic activity in the transfer hydrogenation of acetophenone.

Journal: Inorganic chemistry 20101206

Title: Synthesis of monoacylated derivatives of 1,2- cyclohexanediamine. Evaluation of their catalytic activity in the preparation of Wieland-Miescher ketone.

Journal: The Journal of organic chemistry 20101203

Title: A highly selective fluorescence-based polymer sensor incorporating an (R,R)-salen moiety for Zn(2+) detection.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20101115

Title: Syntheses, structures, and magnetic properties of diphenoxo-bridged Cu(II)Ln(III) and Ni(II)(low-spin)Ln(III) compounds derived from a compartmental ligand (Ln = Ce-Yb).

Journal: Inorganic chemistry 20101004

Title: A new [(1R,2R)-1,2-diaminocyclohexane]platinum(II) complex: formation by nitrate-acetonitrile ligand exchange.

Journal: Acta crystallographica. Section C, Crystal structure communications 20101001

Title: Structural properties of trans-cyclohexane-1,2-diamine complexes of copper(II) and zinc(II) acesulfamates.

Journal: Acta crystallographica. Section C, Crystal structure communications 20101001

Title: New chiral calixsalen chromium complexes: recyclable asymmetric catalysts.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100924

Title: Minimalist end groups for control of absolute helicity in salen- and salophen-based metallofoldamers.

Journal: Organic letters 20100917

Title: Stereoselective synthesis of ring C-hexasubstituted trianglamines.

Journal: Organic & biomolecular chemistry 20100907

Title: Triphenylamine-based rhombimine macrocycles with solution interconvertable conformation.

Journal: Organic & biomolecular chemistry 20100821

Title: Synthesis, characterization, and theoretical studies of metal complexes derived from the chiral tripyridyldiamine ligand Bn-CDPy3.

Journal: Inorganic chemistry 20100607

Title: Oligopyrenotides: abiotic, polyanionic oligomers with nucleic acid-like structural properties.

Journal: Journal of the American Chemical Society 20100602

Title: Genetic polymorphism of GSTP1: prediction of clinical outcome to oxaliplatin/5-FU-based chemotherapy in advanced gastric cancer.

Journal: Journal of Korean medical science 20100601

Title: Dichlorido[(R,R)-N,N,N-tribenzyl-cyclo-hexane-1,2-diamine-κN,N]copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: (1R,2R)-N,N'-Bis[1-(2-pyrid-yl)ethyl-idene]cyclo-hexane-1,2-diamine.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Efficient direct asymmetric vinylogous Michael addition reactions of gamma-butenolides to chalcones catalyzed by vicinal primary-diamine salts.

Journal: Chemical communications (Cambridge, England) 20100328

Title: Chiral and nonchiral [OsX2(diphosphane)(diamine)] (X: Cl, OCH2CF3) complexes for fast hydrogenation of carbonyl compounds.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100308

Title: Transition from enantioselective high performance to ultra-high performance liquid chromatography: A case study of a brush-type chiral stationary phase based on sub-5-micron to sub-2-micron silica particles.

Journal: Journal of chromatography. A 20100212

Title: Octahedral copper(II) and tetrahedral copper(I) double-strand helicates: chiral self-recognition and redox behavior.

Journal: Inorganic chemistry 20100201

Title: Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney.

Journal: Rapid communications in mass spectrometry : RCM 20100201

Title: Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.

Journal: Molecular pain 20100101

Title: Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.

Journal: Bioorganic & medicinal chemistry 20091215

Title: Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties.

Journal: Bioorganic & medicinal chemistry 20091215

Title: (R,R)-4,4'-Dibromo-2,2'-[cyclo-hexane-1,2-diylbis(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: Synthesis, spectroscopic, structural characterization, electrochemical and antimicrobial activity studies of the Schiff base ligand and its transition metal complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091015

Title: (R,R)-(N,N'-Diferrocenylcyclo-hexane-1,2-diyldiimino)dibenzonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: Cyclo-hexane-1,2-diammonium bis-(pyridine-2-carboxyl-ate).

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: Synthesis of chiral large-ring triangular salen ligands and structural characterization of their complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20090914

Title: 2,2'-Bipyrrolidine versus 1,2-diaminocyclohexane as chiral cores for helically wrapping diamine-diolate ligands.

Journal: Inorganic chemistry 20090907

Title: Critical role of external axial ligands in chirality amplification of trans-cyclohexane-1,2-diamine in salen complexes.

Journal: Journal of the American Chemical Society 20090902

Title: 4,4',6,6'-Tetra-hydro-seleno-2,2'-[(E,E)-cyclo-hexane-1,2-diylbis(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090901

Title: Diamond- and graphite-like octacyanometalate-based polymers induced by metal ions.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090803

Title: Quantification of trace elements in natural samples by electrospray ionization mass spectrometry with a size-exclusion column based on the formation of metal-aminopolycarboxylate complexes.

Journal: Analytical chemistry 20090801

Title: Simple cyclohexanediamine-derived primary amine thiourea catalyzed highly enantioselective conjugate addition of nitroalkanes to enones.

Journal: Organic letters 20090702

Title: trans-cyclopentane-1,2-diamine: the second youth of the forgotten diamine.

Journal: Chemical Society reviews 20090701

Title: {2,2'-[Cyclo-hexane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: Enantioselective organocatalytic michael addition of malonates to alpha,beta-unsaturated ketones.

Journal: Organic letters 20090205

Title: Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.

Journal: Bioorganic & medicinal chemistry 20090201

Title: Role of oxaliplatin in the treatment of colorectal cancer.

Journal: Therapeutics and clinical risk management 20090101

Title: Oxaliplatin: pre-clinical perspectives on the mechanisms of action, response and resistance.

Journal: Ecancermedicalscience 20090101

Title: Lanthanide complexes of the heterochiral nonaaza macrocycle: switching the orientation of the helix axis.

Journal: Inorganic chemistry 20081215

Title: The effect of complex stoichiometry in supramolecular chirality transfer to zinc bisporphyrin systems.

Journal: Chemical communications (Cambridge, England) 20081207

Title: Excellent chiralselectivity in sulfur-bridged CoIIIMCoIII (M = NiII and PdII) trinuclear complexes containing 1,2-cyclohexanediamine.

Journal: Dalton transactions (Cambridge, England : 2003) 20081128

Title: Zn(ii), Cd(ii) and Pb(ii) complexation with pyridinecarboxylate containing ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20081114

Title: Chiral iminospherand of a tetrahedral symmetry spontaneously assembled in a [6 + 4] cyclocondensation.

Journal: Organic letters 20081106

Title: [N,N,N',N'-Tetra-kis(benzimidazol-2-yl-meth-yl)cyclo-hexane-1,2-diamine]-nickel(II) dinitrate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy.

Journal: British journal of cancer 20081007

Title: Synthesis, X-ray crystallographic, and NMR characterizations of platinum(II) and platinum(IV) pyrophosphato complexes.

Journal: Inorganic chemistry 20080915

Title: Ferroelectric heterobimetallic clusters with ferromagnetic interactions.

Journal: Inorganic chemistry 20080915

Title: Stereoselective synthesis and biological evaluation of 3,4-diaminocyclohexanecarboxylic acid derivatives as factor Xa inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20080815

Title: Kinetic resolution of esters via metal catalyzed methanolysis reactions.

Journal: Organic & biomolecular chemistry 20080807

Title: Two-dimensional hybrid germanium zeotype formed by selective coordination of the trans-1,2-diaminocyclohexane isomer to the ge atom: heterogeneous acid-base bifunctional catalyst.

Journal: Inorganic chemistry 20080804

Title: Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics.

Journal: Bioorganic & medicinal chemistry 20080801

Title: (E,E)-N,N'-Bis-(4-methoxy-benzyl-idene)cyclo-hexane-1,2-diamine.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: {4,4',6,6'-Tetra-chloro-2,2'-[(spiro-[4.4]nonane-1,6-di-yl)bis-(nitrilo-methyl-idyne)]diphenolato-κO,N,N',O'}nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080701

Title: Instantaneous low temperature gelation by a multicomponent organogelator liquid system based on ammonium salts.

Journal: Journal of the American Chemical Society 20080625

Title: Trans-cyclohexanediamines prevent thermal inactivation of protein: role of hydrophobic and electrostatic interactions.

Journal: The protein journal 20080601

Title: 1,2-Bis[N'-(2,2-dimethyl-propionyl)thio-ureido]cyclo-hexa-ne.

Journal: Acta crystallographica. Section E, Structure reports online 20080501

Title: Discrimination of enantiomers of alpha-amino acids by chiral derivatizing reagents from trans-1,2-diaminocyclohexane.

Journal: Chirality 20080301

Title: Bis[N,N'-bis-[(1H-pyrrol-2-yl)methyl-ene]cyclo-hexane-1,2-diamine]titanium(IV) tetra-hydro-furan solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Leishmanicidal and trypanocidal activities of 2-aminocyclohexanol and 1,2-cyclohexanediamine derivatives.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs.

Journal: Metal-based drugs 20080101

Title: Designed folding of pseudopeptides: the transformation of a configurationally driven preorganization into a stereoselective multicomponent macrocyclization reaction.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Oxaliplatin for metastatic colon cancer in a patient with renal failure.

Journal: Clinical medicine. Oncology 20080101

Title: New synthetic path to 2,2'-bipyridine-5,5'-dicarbaldehyde and its use in the [3+3] cyclocondensation with trans-1,2-diaminocyclohexane.

Journal: Organic letters 20071220

Title: Supramolecular structures of bis-thionooxalamic acid esters derived from (+/-)-cyclohexane-1,2-diamine and (+/-)-1,2-diphenylethylenediamine.

Journal: Acta crystallographica. Section C, Crystal structure communications 20071201

Title: trans-Cyclohexane-1,2-diamine is a weak director of absolute helicity in chiral nickel-salen complexes.

Journal: Journal of the American Chemical Society 20070926

Title: Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070828

Title: Dinuclear platinum complexes with biological relevance based on the 1,2-diaminocyclohexane carrier ligand.

Journal: Inorganic chemistry 20070723

Title: Enantioselective fluorescent recognition of chiral acids by cyclohexane-1,2-diamine-based bisbinaphthyl molecules.

Journal: The Journal of organic chemistry 20070622

Title: The impact of different chelating leaving groups on the substitution kinetics of mononuclear Pt(II)(1,2-trans-R,R-diaminocyclohexane)(X-Y) complexes.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501

Title: Distinct M and P helical complexes of H2O and metal ions NiII, CuII, and ZnII with enantiomerically pure chiral bis(pyrrol-2-ylmethyleneamine)cyclohexane ligands: crystal structures and circular dichroism properties.

Journal: Inorganic chemistry 20070430

Title: A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin?

Journal: ChemMedChem 20070401

Title: Synthesis and stereoselective DNA binding abilities of new optically active open-chain polyamines.

Journal: The Journal of organic chemistry 20070316

Title: Asymmetric amplification in catalysis by trans-1,2-diaminocyclohexane bistriflamide.

Journal: Organic letters 20070118

Title: Review of the toxicology of three alkyl diamines.

Journal: Drug and chemical toxicology 20070101

Title: Chiral macrocyclic aliphatic oligoimines derived from trans-1,2-diaminocyclohexane.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Pyridine and phosphonate containing ligands for stable lanthanide complexation. An experimental and theoretical study to assess the solution structure.

Journal: Dalton transactions (Cambridge, England : 2003) 20061207

Title: Pyridine- and phosphonate-containing ligands for stable Ln complexation. Extremely fast water exchange on the Gd(III) chelates.

Journal: Inorganic chemistry 20061016

Title: Flexibility of inorganic tennis ball structures inducing anion selectivity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20060918

Title: Asymmetric transfer hydrogenation catalysed by hydrophobic dendritic DACH-rhodium complex in water.

Journal: Organic & biomolecular chemistry 20060907

Title: Synthesis and characterization of amidate bridged dimeric and oligomeric platinum complexes having short platinum-platinum interactions.

Journal: Dalton transactions (Cambridge, England : 2003) 20060728

Title: Luminescent amidate-bridged one-dimensional platinum(II)-thallium(I) coordination polymers assembled via metallophilic attraction.

Journal: Inorganic chemistry 20060710

Title: Unprecedented selectivity in the formation of large-ring oligoimines from conformationally bistable chiral diamines.

Journal: Organic letters 20060706

Title: Racemic N-aryl bis(amidines) and bis(amidinates): on the trail of enantioselective organolanthanide catalysts.

Journal: Dalton transactions (Cambridge, England : 2003) 20060328

Title: Anticancer activity of a series of platinum complexes integrating demethylcantharidin with isomers of 1,2-diaminocyclohexane.

Journal: Bioorganic & medicinal chemistry letters 20060315

Title: Angular variation of linewidths in single-crystal EPR spectra.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060313

Title: Trianglamines--readily prepared, conformationally flexible inclusion-forming chiral hexamines.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20060208

Title: Determination of different classes of amines with capillary zone electrophoresis and contactless conductivity detection.

Journal: Electrophoresis 20060201

Title: Lanthanide complexes of chiral 3 + 3 macrocycles derived from (1R,2R)-1,2-diaminocyclohexane and 2,6-diformyl-4-methylphenol.

Journal: Dalton transactions (Cambridge, England : 2003) 20060114

Title: Synthesis, structure, and magnetic behavior of a series of trinuclear Schiff base complexes of 5f (UIV, ThIV) and 3d (CuII, ZnII) ions.

Journal: Inorganic chemistry 20060109

Title: Studies on the synthesis, characterization, binding with DNA and activities of two cis-planaramineplatinum(II) complexes of the form: cis-PtL(NH3)Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine.

Journal: BMC chemical biology 20060101

Title: Chiral trimethylsilylated C2-symmetrical diamines as phosphorous derivatizing agents for the determination of the enantiomeric excess of chiral alcohols by 1H NMR.

Journal: Beilstein journal of organic chemistry 20060101

Title: Management of oxaliplatin-induced peripheral neuropathy.

Journal: Therapeutics and clinical risk management 20051201

Title: Rhombimines-cyclic tetraimines of trans-1,2-diaminocyclohexane shaped by the diaryl ether structural motif.

Journal: The Journal of organic chemistry 20051125

Title: Marked dependence on carrier-ligand bulk but not on carrier-ligand chirality of the duplex versus single-strand forms of a DNA oligonucleotide with a series of G-Pt(II)-G intrastrand cross-links modeling cisplatin-DNA adducts.

Journal: Journal of the American Chemical Society 20051116

Title: New 2+2, 3+3 and 4+4 macrocycles derived from 1,2-diaminocyclohexane and 2,6-diformylpyridine.

Journal: Organic & biomolecular chemistry 20050907

Title: Enantioselective analysis of an asymmetric reaction using a chiral fluorosensor.

Journal: Organic letters 20050901

Title: Syntheses and ligand interconversions of copper(II) derivatives of the metalloligand [Pt2(mu-S)2(PPh3)4].

Journal: Dalton transactions (Cambridge, England : 2003) 20050821

Title: Colorimetric enantiodiscrimination of alpha-amino acids in protic media.

Journal: Journal of the American Chemical Society 20050608

Title: Exciton chirality in trans-1,2-diamidocyclohexanes: fluorescent chromophores.

Journal: Chirality 20050601

Title: Large molecular motions are tolerated in crystals of diamine double salt of trans-chlorocinnamic acids with trans-1,2-diaminocyclohexane.

Journal: Organic letters 20050512

Title: A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients.

Journal: British journal of cancer 20050509

Title: Chemistry of ruthenium(II) monohydride and dihydride complexes containing pyridyl donor ligands including catalytic ketone H2-hydrogenation.

Journal: Inorganic chemistry 20050404

Title: Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells.

Journal: British journal of cancer 20050328

Title: Shape-complementarity in the recognition of tricarboxylic acids by a [3+3] polyazacyclophane receptor.

Journal: The Journal of organic chemistry 20050318

Title: A cyclohexyl-1,2-diamine-derived bis(binaphthyl) macrocycle: enhanced sensitivity and enantioselectivity in the fluorescent recognition of mandelic acid.

Journal: Angewandte Chemie (International ed. in English) 20050304

Title: Oxaliplatin activity in head and neck cancer cell lines.

Journal: Cancer chemotherapy and pharmacology 20050301

Title: Chromatographic evaluation of poly (trans-1,2-cyclohexanediyl-bis acrylamide) as a chiral stationary phase for HPLC.

Journal: Journal of chromatography. A 20050225

Title: A systematic study of the interactions between chemical partners (metal, ligands, counterions, and support) involved in the design of Al2O3-supported nickel catalysts from diamine-Ni(II) chelates.

Journal: The journal of physical chemistry. B 20050224

Title: New hybrid polymeric liquid chromatography chiral stationary phase prepared by surface-initiated polymerization.

Journal: Journal of chromatography. A 20050128

Title: Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050103

Title: Synthesis, structure, and contrasting chiroptical properties of large trianglimine macrocycles.

Journal: Chirality 20050101

Title: A Phase II study of oxaliplatin in urothelial cancer.

Journal: Urologic oncology 20050101

Title: Survey of oxaliplatin-associated neurotoxicity using an interview-based questionnaire in patients with metastatic colorectal cancer.

Journal: BMC cancer 20050101

Title: Synthesis and in vitro antitumor potency of (cyclohexane-1,2-diamine)platinum(II) complexes with aminotris(methylenephosphonic acid) as bone-seeking ligand.

Journal: Bioinorganic chemistry and applications 20050101

Title: A novel approach to biodegradable block copolymers of epsilon-caprolactone and delta-valerolactone catalyzed by new aluminum metal complexes.

Journal: Macromolecular bioscience 20041215

Title: Chemoenzymatic preparation of optically active trans-cyclohexane-1,2-diamine derivatives: an efficient synthesis of the analgesic U-(-)-50,488.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20041105

Title: Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible.

Journal: European journal of medicinal chemistry 20040801

Title: Kinetic resolution of amines: a highly enantioselective and chemoselective acetylating agent with a unique solvent-induced reversal of stereoselectivity.

Journal: Angewandte Chemie (International ed. in English) 20040621

Title: Influence of trans-1,2-diaminocyclohexane structure and mixed carboxylic/phosphonic group combinations on samarium-153 chelation capacity and stability.

Journal: European journal of medicinal chemistry 20040501

Title: 5H-oxazol-4-ones as building blocks for asymmetric synthesis of alpha-hydroxycarboxylic acid derivatives.

Journal: Journal of the American Chemical Society 20040225

Title: Planar chiral dianthranilide and dithiodianthranilide molecules: optical resolution, chiroptical spectra, and molecular self-assembly.

Journal: The Journal of organic chemistry 20040220

Title: Parallel screening of homogeneous copper catalysts for the oxidation of benzylic alcohols with molecular oxygen in aqueous solutions.

Journal: Journal of combinatorial chemistry 20040101

Title: X-ray structure and circular dichroism of pure rotamers of bis[guanosine-5'-monophosphate(-1)](N,N,N',N'-tetramethylcyclohexyl-1,2-diamine)platinum(II) complexes that have R,R and S,S configurations at the asymmetric diamine.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20031215

Title: Structure, modelling and dynamic behaviour of aza- and azaoxamacrocyclic ligands derived from (R,R)-1,2-diaminocyclohexane.

Journal: Organic & biomolecular chemistry 20031121

Title: Synthesis, characterization, and in vitro antitumor activity of osteotropic diam(m)ineplatinum(II) complexes bearing a N,N-bis(phosphonomethyl)glycine ligand.

Journal: Journal of medicinal chemistry 20031106

Title: Dynamic kinetic asymmetric cycloadditions of isocyanates to vinylaziridines.

Journal: Journal of the American Chemical Society 20031001

Title: Platinum-based anticancer agents: innovative design strategies and biological perspectives.

Journal: Medicinal research reviews 20030901

Title: Synthesis of amylose acetates and amylose sulfates with high structural uniformity.

Journal: Carbohydrate research 20030623

Title: A metal-centered hydrophobic pocket recognizing pyridine over piperidine.

Journal: Journal of the American Chemical Society 20030618

Title: Nitrogen lone pair interactions in organic molecules: a photoelectron spectroscopic study.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601

Title: Ion-pair extraction behavior of divalent metal cations using neutral di-Schiff base ligands derived from 1,2-cyclohexanediamine and o-phenylenediamine.

Journal: Talanta 20030410

Title: Shape-controlled bridged silsesquioxanes: hollow tubes and spheres.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20030404

Title: Synthesis of 1,4-diazines by ring expansion of 1,3-diazines.

Journal: The Journal of organic chemistry 20030321

Title: Tumour-inhibiting platinum complexes--state of the art and future perspectives.

Journal: Reviews of physiology, biochemistry and pharmacology 20030101

Title: Synthesis, characterization and preliminary cytotoxicity assays of poly(ethylene glycol)-malonato-Pt-DACH conjugates.

Journal: European journal of medicinal chemistry 20030101

Title: Well-defined enantiopure 1,1'-binaphthyl-based oligomers: synthesis, structure, photophysical properties, and chiral sensing.

Journal: The Journal of organic chemistry 20021101

Title: The unusual role of CO transfer in molybdenum-catalyzed asymmetric alkylations.

Journal: Journal of the American Chemical Society 20021030

Title: The copper-catalyzed N-arylation of indoles.

Journal: Journal of the American Chemical Society 20021002

Title: Remarkable stability and enhanced optical activity of a chiral supramolecular bis-porphyrin tweezer in both solution and solid state.

Journal: Journal of the American Chemical Society 20020925

Title: A practical catalytic asymmetric addition of alkyl groups to ketones.

Journal: Journal of the American Chemical Society 20020918

Title: Ferromagnetism and chirality in two-dimensional cyanide-bridged bimetallic compounds.

Journal: Inorganic chemistry 20020909

Title: Total synthesis of the antiviral glycolipid cycloviracin B.

Journal: Journal of the American Chemical Society 20020904

Title: Chiral N-alkyl-2,4,6-triphenylpyridiniums as enantioselective triplet photosensitizers. laser flash photolysis and preparative studies.

Journal: The Journal of organic chemistry 20020726

Title: Preparation and self-assembly of chiral porphyrin diads on the gold electrodes of quartz crystal microbalances: a novel potential approach to the development of enantioselective chemical sensors.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020603

Title: Preparation and cell growth inhibitory activity of [PtR(2)L(2)] (R=polyfluorophenyl, L(2)=diene, cyclohexane-1,2-diamine (chxn) or cis-(dimethyl sulfoxide)(2)) and the X-ray crystal structure of [Pt(C(6)F(5))(2)(cis-chxn)].

Journal: Journal of inorganic biochemistry 20020428

Title: The influence of plasma proteins and platelets on oxygen radical production and F-actin distribution in neutrophils adhering to polymer surfaces.

Journal: Biomaterials 20020401

Title: Folding of aromatic oligoimides of trans-1,2-diaminocyclohexane.

Journal: Chemical communications (Cambridge, England) 20020321

Title: Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay.

Journal: Biochemistry 20020122

Title: Application of capillary electrophoresis-mass spectrometry for the investigation of the binding behavior of oxaliplatin to 5'-GMP in the presence of the sulfur-containing amino acid L-methionine.

Journal: Electrophoresis 20020101

Title: An approach to a chiral cycloalkanone-mediated asymmetric epoxidation of stilbene with oxone.

Journal: Chemical & pharmaceutical bulletin 20011201

Title: Irinotecan plus oxaliplatin: a promising combination for advanced colorectal cancer.

Journal: Clinical colorectal cancer 20011101

Title: Occupational contact sensitization to 1,2-diaminocyclohexane.

Journal: Contact dermatitis 20010801

Title: [Oxaliplatin tolerance in the treatment of metastatic colorectal cancers].

Journal: Bulletin du cancer 20010801

Title: Geminal dicarboxylates as carbonyl surrogates for asymmetric synthesis. Part I. Asymmetric addition of malonate nucleophiles.

Journal: Journal of the American Chemical Society 20010425

Title: Ketalization of gaseous acylium ions.

Journal: Journal of the American Society for Mass Spectrometry 20010201

Title: The in vitro antitumour profile of some 1,2-diaminocyclohexane organotin complexes.

Journal: Journal of inorganic biochemistry 20010115

Title: [Oxaliplatin: preclinical in vitro studies].

Journal: Tumori 20010101

Title: Potent and use-dependent block of cardiac sodium channels by U-50,488H, a benzeneacetamide kappa opioid receptor agonist.

Journal: Experimental and clinical cardiology 20010101

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Tags:694-83-7 Molecular Formula|694-83-7 MDL|694-83-7 SMILES|694-83-7 1,2-Diaminocyclohexane |Organic_Building_Blocks