Home Nitro Compounds 528-29-0
528-29-0,MFCD00007093
Catalog No.:AA003DBY

528-29-0 | 1,2-Dinitrobenzene

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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003DBY
Chemical Name:
1,2-Dinitrobenzene
CAS Number:
528-29-0
Molecular Formula:
C6H4N2O4
Molecular Weight:
168.1070
MDL Number:
MFCD00007093
SMILES:
O=N(=O)c1ccccc1N(=O)=O
NSC Number:
60682
Properties
Properties
 
BP:
318.0°C  

Computed Properties
 
Complexity:
173  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
XLogP3:
1.7  

Literature

Title: A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living cells based on thiolysis of dinitrophenyl ether.

Journal: Chemical communications (Cambridge, England) 20121104

Title: Placing supercritical fluid chromatography one step ahead of reversed-phase high performance liquid chromatography in the achiral purification arena: a hydrophilic interaction chromatography cross-linked diol chemistry as a new generic stationary phase.

Journal: Journal of chromatography. A 20120810

Title: Characterization of bifunctional sphingolipid Δ4-desaturases/C4-hydroxylases of trypanosomatids by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Molecular and biochemical parasitology 20120701

Title: Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides.

Journal: Journal of proteomics 20120627

Title: Characterization of a model of tracheal plasma extravasation in passively sensitized rats using anti-allergic and anti-inflammatory drugs by oral and intratracheal route.

Journal: Pulmonary pharmacology & therapeutics 20120201

Title: Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in chagas disease pathogenesis.

Journal: PloS one 20120101

Title: Plasmodium riboprotein PfP0 induces a deviant humoral immune response in Balb/c mice.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting.

Journal: PloS one 20120101

Title: Three Drosophila Hox complex microRNAs do not have major effects on expression of evolutionarily conserved Hox gene targets during embryogenesis.

Journal: PloS one 20120101

Title: [Anthocyanidin inhibits immunoglobulin E-mediated allergic response in mast cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120101

Title: Comparative vibrational analysis of 1,2-Dinitro benzene and 1-Fluoro-3-nitro benzene: a combined experimental (FT-IR and FT-Raman) and theoretical study (DFT/B3LYP/B3PW91).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111215

Title: A chemically induced vaccine strategy for prostate cancer.

Journal: ACS chemical biology 20111118

Title: Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine.

Journal: Cancer immunology, immunotherapy : CII 20110701

Title: RP-HPLC method for quantitative determination of cystathionine, cysteine and glutathione: An application for the study of the metabolism of cysteine in human brain.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

Title: Synthesis and evaluation of a chiral stationary phase based on quinine: enantioresolution of dinitrophenyl derivatives of α-amino acids.

Journal: Journal of chromatography. A 20110610

Title: A selective fluoride encapsulated neutral tripodal receptor capsule: solvatochromism and solvatomorphism.

Journal: Chemical communications (Cambridge, England) 20110507

Title: Studies on the performance of different coiled column configurations for compact type-I countercurrent chromatography.

Journal: Journal of separation science 20110501

Title: Nitroreductase activity of ferredoxin reductase BphA4 from Dyella ginsengisoli LA-4 by catalytic and structural properties analysis.

Journal: Applied microbiology and biotechnology 20110201

Title: Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L.

Journal: Clinical and molecular allergy : CMA 20110101

Title: Multicolor fluorescent in situ hybridization to define abutting and overlapping gene expression in the embryonic zebrafish brain.

Journal: Neural development 20110101

Title: Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages.

Journal: PloS one 20110101

Title: Analysis of proteasomal proteolysis during the in vitro metacyclogenesis of Trypanosoma cruzi.

Journal: PloS one 20110101

Title: Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening.

Journal: PloS one 20110101

Title: Endogenous synthesis of corticosteroids in the hippocampus.

Journal: PloS one 20110101

Title: Netrin signaling breaks the equivalence between two identified zebrafish motoneurons revealing a new role of intermediate targets.

Journal: PloS one 20110101

Title: Tracking human contact allergens: from mass spectrometric identification of peptide-bound reactive small chemicals to chemical-specific naive human T-cell priming.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging.

Journal: Geriatrics & gerontology international 20100701

Title: Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning.

Journal: PLoS genetics 20100701

Title: Ovarian cancer immunotherapy: opportunities, progresses and challenges.

Journal: Journal of hematology & oncology 20100101

Title: Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis.

Journal: PloS one 20100101

Title: IL-33 is produced by mast cells and regulates IgE-dependent inflammation.

Journal: PloS one 20100101

Title: Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cell.

Journal: Cell communication and signaling : CCS 20100101

Title: 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2.

Journal: Breast cancer research : BCR 20100101

Title: Deficiency of activating Fcγ-receptors reduces hepatic clearance and deposition of IC and increases CIC levels in mercury-induced autoimmunity.

Journal: PloS one 20100101

Title: Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data.

Journal: Journal of allergy 20100101

Title: Intracellular scavenging activity of Trolox (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid) in the fission yeast, Schizosaccharomyces pombe.

Journal: Journal of natural science, biology, and medicine 20100101

Title: Nanoparticle-mediated IgE-receptor aggregation and signaling in RBL mast cells.

Journal: Journal of the American Chemical Society 20091202

Title: Comparative application of microwave, ultrasonication, ultracentrifugation and conventional heating for preparation of sample as dinitrophenyl derivative for direct enantioseparation of certain amino alcohols and 1-amino-2-propanol from vitamin B12 hydrolysate on alpha1-acid glycoprotein and beta-cyclodextrin columns.

Journal: Journal of chromatography. A 20091106

Title: High-performance liquid chromatographic enantioseparation of methanobenzazocines.

Journal: Journal of chromatography. A 20091106

Title: Strategy to prevent drug-related hypersensitivity in folate-targeted hapten immunotherapy of cancer.

Journal: The AAPS journal 20090901

Title: Advancing drug innovation for neglected diseases-criteria for lead progression.

Journal: PLoS neglected tropical diseases 20090801

Title: Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1.

Journal: Toxicology and applied pharmacology 20090715

Title: Analytical and preparative enantioseparation of DL-penicillamine and DL-cysteine by high-performance liquid chromatography on alpha-acid glycoprotein and beta-cyclodextrin columns using ninhydrin as a reversible tagging reagent.

Journal: Journal of chromatography. A 20090410

Title: Association mechanism of S-dinitrophenyl glutathione with two glutathione peroxidase mimics: 2, 2 cent-ditelluro- and 2, 2 cent-diseleno-bridged b-cyclodextrins.

Journal: Molecules (Basel, Switzerland) 20090225

Title: Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients.

Journal: Journal of translational medicine 20090101

Title: Folate-targeted hapten immunotherapy of adjuvant-induced arthritis: comparison of hapten potencies.

Journal: Molecular pharmaceutics 20090101

Title: Human CD34/CD90 ASCs are capable of growing as sphere clusters, producing high levels of VEGF and forming capillaries.

Journal: PloS one 20090101

Title: Inhibition of the antigen-induced activation of RBL-2H3 cells by Gab2 siRNA.

Journal: Cellular & molecular immunology 20081201

Title: 1-(2,4-Dinitro-phenyl)-3-(4-methyl-phenyl)-4-phenyl-sulfanyl-1H-pyrazole.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Divergence of catalytic mechanism within a glycosidase family provides insight into evolution of carbohydrate metabolism by human gut flora.

Journal: Chemistry & biology 20081020

Title: Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines.

Journal: Cancer immunology, immunotherapy : CII 20081001

Title: High sensitivity molecular detection with enzyme-linked immuno-sorbent assay (ELISA)-type immunosensing.

Journal: Nanotechnology 20080917

Title: 13C and 15N NMR chemical shifts of 1-(2',4'-dinitrophenyl) and 1-(2',4',6'-trinitrophenyl) pyrazoles in the solid state and in solution.

Journal: Magnetic resonance in chemistry : MRC 20080701

Title: (E)-2-Furyl methyl ketone 2,4-dinitro-phenyl-hydrazone.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: 6,6'-Dimeth-oxy-2,2',3,3',5-penta-nitro-1,1'-biphen-yl.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: N-(2,4-Dinitro-phen-yl)dehydro-abietyl-amine.

Journal: Acta crystallographica. Section E, Structure reports online 20080501

Title: Biliprotein maturation: the chromophore attachment.

Journal: Molecular microbiology 20080401

Title: Fluorescence affinity sensing by using a self-contained fluid manoeuvring microfluidic chip.

Journal: The Analyst 20080401

Title: Inhibition of the antigen-induced activation of RBL-2H3 cells by sinomenine.

Journal: International immunopharmacology 20080301

Title: 1-(2,4-Dinitro-phen-yl)-5-ferrocenyl-3-methyl-1H-pyrazole.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress.

Journal: BMC complementary and alternative medicine 20080101

Title: Development of automated brightfield double in situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence in situ hybridization (FISH).

Journal: Diagnostic pathology 20080101

Title: Rod1, an arrestin-related protein, is phosphorylated by Snf1-kinase in Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications 20071214

Title: Absence of functional peroxisome proliferator-activated receptor-alpha enhanced ileum permeability during experimental colitis.

Journal: Shock (Augusta, Ga.) 20070801

Title: Improved systemic pharmacokinetics, biodistribution, and antitumor activity of CpG oligodeoxynucleotides complexed to endogenous antibodies in vivo.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070716

Title: Rab27b regulates mast cell granule dynamics and secretion.

Journal: Traffic (Copenhagen, Denmark) 20070701

Title: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles.

Journal: The FEBS journal 20070601

Title: Dinitrophenyl derivatization of imino acids, spectral characteristics and HPLC analysis: application in urinary peptide-derived hydroxyproline and proline assay.

Journal: Annals of clinical biochemistry 20070301

Title: Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation.

Journal: Arthritis research & therapy 20070101

Title: Folate-targeted dinitrophenyl hapten immunotherapy: effect of linker chemistry on antitumor activity and allergic potential.

Journal: Molecular pharmaceutics 20070101

Title: [A new approach to the use of fluorogenic dinitrophenyl-containing substrates for determining the proteolytic activity of aspartyl proteinases].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Dinitrophenyl ligand substrates and their application to immunosensors.

Journal: Biosensors & bioelectronics 20060715

Title: Boron dipyrromethene dyes: a rational avenue for sensing and light emitting devices.

Journal: Dalton transactions (Cambridge, England : 2003) 20060621

Title: Development of dinitrophenylated cyclodextrin derivatives for enhanced enantiomeric separations by high-performance liquid chromatography.

Journal: Journal of chromatography. A 20060519

Title: Iron-induced oxidative brain injury after experimental intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20060101

Title: Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline.

Journal: Genome biology 20060101

Title: Modification of Cepsilon mRNA expression by EBV-encoded latent membrane protein 1.

Journal: Mediators of inflammation 20060101

Title: Intramolecular nitro-assisted proton transfer in photoirradiated 2-(2',4'-dinitrobenzyl)pyridine: polarized optical spectroscopic study and electronic structure calculations.

Journal: The journal of physical chemistry. A 20050818

Title: Application of fluorescence microscopy for investigation of cellular distribution of dinuclear platinum anticancer drugs.

Journal: Journal of medicinal chemistry 20050811

Title: Spectroscopic investigations of solvent effect on chiral interactions.

Journal: The journal of physical chemistry. B 20050630

Title: Antigen-IgE desensitization in signal transducer and activator of transcription 6-deficient mast cells by suboptimal doses of antigen.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050501

Title: Bioelectrocatalytic signaling from immunosensors with back-filling immobilization of glucose oxidase on biorecognition surfaces.

Journal: Biotechnology and bioengineering 20050330

Title: Oxidative DNA injury after experimental intracerebral hemorrhage.

Journal: Brain research 20050328

Title: Synthesis and application of poly(phenylene ethynylene)s for bioconjugation: a conjugated polymer-based fluorogenic probe for proteases.

Journal: Journal of the American Chemical Society 20050316

Title: A new selective substrate for cathepsin E based on the cleavage site sequence of alpha2-macroglobulin.

Journal: Biological chemistry 20050301

Title: Antibodies as drug carriers III: design of oligonucleotides with enhanced binding affinity for immunoglobulin G.

Journal: Pharmaceutical research 20050101

Title: Intracerebral hemorrhage induces edema and oxidative stress and alters N-methyl-D-aspartate receptor subunits expression.

Journal: Acta neurochirurgica. Supplement 20050101

Title: M-Vax: an autologous, hapten-modified vaccine for human cancer.

Journal: Expert review of vaccines 20041001

Title: Label-free, real-time monitoring of IgE-mediated mast cell activation on microelectronic cell sensor arrays.

Journal: Journal of immunological methods 20040901

Title: Targeted radiosensitisation by pegylated liposome-encapsulated 3', 5'-O-dipalmitoyl 5-iodo-2'-deoxyuridine in a head and neck cancer xenograft model.

Journal: British journal of cancer 20040719

Title: Understanding thymus-independent antigen-induced reduction of thymus-dependent immune responses.

Journal: Immunology 20040701

Title: DNA display III. Solid-phase organic synthesis on unprotected DNA.

Journal: PLoS biology 20040701

Title: Detoxification of amitriptyline by oligochitosan derivatives.

Journal: Biotechnology letters 20040501

Title: Interleukin-2 improves tumour response to DNP-modified autologous vaccine for the treatment of metastatic malignant melanoma.

Journal: British journal of cancer 20040223

Title: Immunopharmacologic analysis of an autologous, hapten-modified human melanoma vaccine.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040201

Title: S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.

Journal: BMC clinical pharmacology 20040101

Title: Selective complex formation of some chromogenic calix[4]arene derivatives detected by Fourier transform infrared spectroscopy 2. Solid experiments.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031201

Title: Design, synthesis, and anticancer properties of 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone and analogues.

Journal: Journal of medicinal chemistry 20031009

Title: Developmental changes in glutathione S-transferase isoforms expression and activity in intrasplenic fetal liver tissue transplants in rats.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901

Title: Semi-quantitative 'spot-test' of cyanide.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030801

Title: Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030731

Title: Calcium-regulated expression of activin A in RBL-2H3 mast cells.

Journal: Cellular signalling 20030601

Title: Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine.

Journal: The Journal of biological chemistry 20030502

Title: The response of adult rat sertoli cells, immortalized by a temperature-sensitive mutant of SV40, to 1,2-dinitrobenzene, 1,3-dinitrobenzene, 2,4-dinitrotoluene, 3,4-dinitrotoluene, and cadmium.

Journal: Cell biology and toxicology 20030401

Title: Protein carbonyl groups as biomarkers of oxidative stress.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030301

Title: Benzaldehyde 2,4-dinitrophenylhydrazone.

Journal: Acta crystallographica. Section C, Crystal structure communications 20030301

Title: Contribution of dead cells to the immunogenicity of an autologous, hapten-modified melanoma vaccine.

Journal: Vaccine 20030130

Title: Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin.

Journal: Journal of neuroscience research 20030115

Title: Immunosuppression in the northern leopard frog (Rana pipiens) induced by pesticide exposure.

Journal: Environmental toxicology and chemistry 20030101

Title: Melanoma Vaccine--AVAX Technologies: DNP-VACC, M-Vax.

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20030101

Title: Pap1-dependent regulation of the GSTII gene from the fission yeast.

Journal: Molecules and cells 20021231

Title: The Pap1-independent induction by metal ions of a third gene encoding glutathione S-transferase gene from the fission yeast.

Journal: Molecules and cells 20021231

Title: Influences of anti-mouse interleukin-6 receptor antibody on immune responses in mice.

Journal: Immunology letters 20021203

Title: Isolation and characterization of a cDNA encoding a Delta8 sphingolipid desaturase from Aquilegia vulgaris.

Journal: Biochemical Society transactions 20021101

Title: TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020915

Title: Probing antigen-antibody binding processes by impedance measurements on ion-sensitive field-effect transistor devices and complementary surface plasmon resonance analyses: development of cholera toxin sensors.

Journal: Analytical chemistry 20020915

Title: Characterization, expression and regulation of a third gene encoding glutathione S-transferase from the fission yeast.

Journal: Biochimica et biophysica acta 20020819

Title: PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance.

Journal: FEBS letters 20020814

Title: Effect of the dose and composition of an autologous hapten-modified melanoma vaccine on the development of delayed-type hypersensitivity responses.

Journal: Cancer immunology, immunotherapy : CII 20020801

Title: Microarray analysis of gene expression in the aging human retina.

Journal: Investigative ophthalmology & visual science 20020801

Title: Bivalent ligands with rigid double-stranded DNA spacers reveal structural constraints on signaling by Fc epsilon RI.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020715

Title: HPLC method for amino acids profile in biological fluids and inborn metabolic disorders of aminoacidopathies.

Journal: Indian journal of clinical biochemistry : IJCB 20020701

Title: Anti-metastatic activity of hapten-modified autologous tumor cell vaccine in an animal tumor model.

Journal: Cancer immunology, immunotherapy : CII 20020601

Title: Autologous cell vaccine as a post operative adjuvant treatment for high-risk melanoma patients (AJCC stages III and IV). The new American Joint Committee on Cancer.

Journal: British journal of cancer 20020520

Title: A second stress-inducible glutathione S-transferase gene from Schizosaccharomyces pombe.

Journal: Biochimica et biophysica acta 20020412

Title: M-Vax: an autologous, hapten-modified vaccine for human cancer.

Journal: Expert opinion on biological therapy 20020301

Title: Azelastine and suplatast shorten the distribution half-life of IgE in rats.

Journal: Mediators of inflammation 20020201

Title: Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals.

Journal: BMC biochemistry 20020101

Title: Chronopotentiometry and Faradaic impedance spectroscopy as signal transduction methods for the biocatalytic precipitation of an insoluble product on electrode supports: routes for enzyme sensors, immunosensors and DNA sensors.

Journal: Biosensors & bioelectronics 20011201

Title: A new and versatile method for determination of thiolamines of biological importance.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010915

Title: Novel findings in inhibition of mast cell-dependent immediate-type cutaneous reactions by Gahmi-Shini-San.

Journal: Clinica chimica acta; international journal of clinical chemistry 20010705

Title: Functional identification of a delta8-sphingolipid desaturase from Borago officinalis.

Journal: Archives of biochemistry and biophysics 20010415

Title: Autologous, hapten-modified vaccine as a treatment for human cancers.

Journal: Vaccine 20010321

Title: Substrate specificity of the integral membrane protease OmpT determined by spatially addressed peptide libraries.

Journal: Biochemistry 20010213

Title: Hapten-induced primary and memory humoral responses are inhibited by the infusion of anti-CD20 monoclonal antibody (IDEC-C2B8, Rituximab).

Journal: Clinical immunology (Orlando, Fla.) 20010201

Title: Methemoglobin formation in human erythrocytes by nitroaromatic explosives.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

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Tags:528-29-0 Molecular Formula|528-29-0 MDL|528-29-0 SMILES|528-29-0 1,2-Dinitrobenzene |Organic_Building_Blocks