Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Discovery of small molecule human FPR1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20110515
Title: Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110201
Title: Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
Journal: Nephrology (Carlton, Vic.) 20110201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Journal: Bioorganic & medicinal chemistry 20101101
Title: Adherence with urate-lowering therapies for the treatment of gout.
Journal: Arthritis research & therapy 20090101
Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal: Journal of medicinal chemistry 20080612
Title: Uric acid lowering therapy: prescribing patterns in a large cohort of older adults.
Journal: Annals of the rheumatic diseases 20080501
Title: MRP7/ABCC10 expression is a predictive biomarker for the resistance to paclitaxel in non-small cell lung cancer.
Journal: Molecular cancer therapeutics 20080501
Title: 2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: design, synthesis, and SAR studies.
Journal: Bioorganic & medicinal chemistry letters 20080115
Title: HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080101
Title: Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity.
Journal: Journal of medicinal chemistry 20071227
Title: Molecular epidemiology of malaria in Cameroon. XXVI. Twelve-year in vitro and molecular surveillance of pyrimethamine resistance and experimental studies to modulate pyrimethamine resistance.
Journal: The American journal of tropical medicine and hygiene 20070801
Title: Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601
Title: Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.
Journal: European journal of pharmacology 20070410
Title: Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Use of cryopreserved transiently transfected cells in high-throughput pregnane X receptor transactivation assay.
Journal: Journal of biomolecular screening 20070301
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201
Title: Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Clinical trials of uric acid lowering for coronary heart disease risk reduction.
Journal: The American journal of medicine 20060401
Title: Pyridazines part 41: synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl)pyridazin-3(2H)-ones.
Journal: Bioorganic & medicinal chemistry letters 20060215
Title: Macrophage uptake and recycling of ascorbic acid: response to activation by lipopolysaccharide.
Journal: Free radical biology & medicine 20051201
Title: Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101
Title: Combined effects of GSTP1 and MRP1 in melanoma drug resistance.
Journal: British journal of cancer 20050725
Title: Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2.
Journal: Biochimica et biophysica acta 20050630
Title: High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands.
Journal: Journal of biomolecular screening 20050601
Title: UDP-glucuronosyltransferases and clinical drug-drug interactions.
Journal: Pharmacology & therapeutics 20050401
Title: Ascorbate uptake in pig coronary artery endothelial cells.
Journal: Molecular and cellular biochemistry 20050301
Title: Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.
Journal: British journal of pharmacology 20041201
Title: Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.
Journal: Journal of the American Society of Nephrology : JASN 20041101
Title: Effect of a selective CYP2C9 inhibitor on the pharmacokinetics of nateglinide in healthy subjects.
Journal: European journal of clinical pharmacology 20040801
Title: Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects.
Journal: Molecular pharmacology 20040401
Title: Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040301
Title: Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones.
Journal: Bioorganic & medicinal chemistry letters 20040119
Title: Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
Journal: The Journal of pharmacology and experimental therapeutics 20040101
Title: Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes.
Journal: Brain research 20031212
Title: Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport.
Journal: Toxicology and applied pharmacology 20031115
Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Journal: Journal of medicinal chemistry 20031009
Title: Functional expression of the multidrug resistance protein 1 in microglia.
Journal: The Journal of pharmacology and experimental therapeutics 20031001
Title: UV or X-irradiation increases the cytoplasmic accumulation of rhodamine 123 in various cancer cell lines.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20030801
Title: Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
Journal: Molecular pharmacology 20030201
Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
Journal: Archives of biochemistry and biophysics 20030101
Title: Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol.
Journal: Glia 20020801
Title: CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701
Title: Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
Journal: Cancer research 20020601
Title: Free radical scavenging properties of sulfinpyrazone.
Journal: Free radical research 20020601
Title: Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2).
Journal: Pharmacology 20020101
Title: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).
Journal: The Journal of biological chemistry 20011207
Title: Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.
Journal: The Journal of biological chemistry 20011012
Title: Resistance to mitoxantrone in multidrug-resistant MCF7 breast cancer cells: evaluation of mitoxantrone transport and the role of multidrug resistance protein family proteins.
Journal: Cancer research 20010715
Title: Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010501
Title: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 19990301
Title: Acute renal failure due to sulfinpyrazone.
Journal: The American journal of the medical sciences 19980501
Title: Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene.
Journal: European journal of drug metabolism and pharmacokinetics 19970101
Title: Antiplatelet therapy in the prevention of stroke.
Journal: Drugs 19910101
Title: Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.
Journal: The Journal of clinical investigation 19900201
Title: Plasmapheresis and antiplatelet agents in the treatment of the hemolytic uremic syndrome secondary to mitomycin.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19860501
Title: Interference by sulphinpyrazone with the antihypertensive effects of oxprenolol.
Journal: European journal of clinical pharmacology 19860101
Title: [Acute tubulo-interstitial nephropathy associated with ingestion of sulfinpyrazone].
Journal: Presse medicale (Paris, France : 1983) 19850223
Title: Sulfinpyrazone: risk for renal insufficiency.
Journal: Archives of internal medicine 19840301
Title: [Acute interstitial nephritis and kidney failure requiring dialysis after sulfinpyrazone therapy].
Journal: Acta medica Austriaca 19840101
Title: Acute renal failure secondary to sulfinpyrazone treatment after myocardial infarction.
Journal: Nephron 19840101
Title: Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment.
Journal: Thrombosis and haemostasis 19831230
Title: Sulfinpyrazone-associated acute renal failure.
Journal: Clinical nephrology 19830701
Title: Decrease in renal function due to sulphinpyrazone treatment early after myocardial infarction.
Journal: Clinical nephrology 19830301
Title: Oliguric acute renal failure after treatment with sulfinpyrazone.
Journal: Clinical nephrology 19830101
Title: [Sulfinpyrazone-associated renal failure (author's transl)].
Journal: Deutsche medizinische Wochenschrift (1946) 19820709
Title: Non oliguric acute renal failure after treatment with sulfinpyrazone.
Journal: Clinical nephrology 19820501
Title: Acute renal failure following sulfinpyrazone therapy.
Journal: South Dakota journal of medicine 19820401
Title: Sulphinpyrazone--induced decrease in renal function: a review of reports with discussion of pathogenesis.
Journal: Acta clinica Belgica 19820101
Title: Renal dysfunction due to anturane.
Journal: The New England journal of medicine 19811105
Title: Acute renal dysfunction due to sulfinpyrazone therapy in post-myocardial infarction cardiomegaly: reversible hypersensitive interstitial nephritis.
Journal: American heart journal 19810801
Title: Renal dysfunction due to anturan.
Journal: The New England journal of medicine 19810709
Title: Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis.
Journal: Japanese heart journal 19810701
Title: Sulfinpyrazone induced uric acid urolithiasis with acute renal failure.
Journal: Connecticut medicine 19810701
Title: Sulphinpyrazone-induced acute renal failure.
Journal: British medical journal (Clinical research ed.) 19810221
Title: [Acute renal failure induced by sulfinpyrazone (author's transl)].
Journal: Nephrologie 19810101
Title: Are agents affecting platelet functions clinically useful?
Journal: The American journal of medicine 19761201
Title: Abnormalities of urinary sediment and renal failure following sulfinpyrazone therapy.
Journal: Archives of internal medicine 19760901
Title: Acute myelomonocytic leukaemia and multiple myeloma after sulphinpyrazone and colchicine treatment of gout.
Journal: British medical journal 19760710
Title: Margulies EH, White AM, Sherry S. Sulfinpyrazone: a review of its pharmacological properties and therapeutic use. Drugs. 1980;20(3):179‐197.
Title: Rüegg M. Antithrombotic effects of sulfinpyrazone in animals: influence on fibrinolysis and sodium arachidonate-induced pulmonary embolism. Pharmacology. 1976;14(6):522‐536.