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86953-79-9,MFCD00216581
Catalog No.:AA003DZL

86953-79-9 | 1-Boc-pyrrolidine

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1g
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5g
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10g
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25g
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100g
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500g
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003DZL
Chemical Name:
1-Boc-pyrrolidine
CAS Number:
86953-79-9
Molecular Formula:
C9H17NO2
Molecular Weight:
171.2368
MDL Number:
MFCD00216581
SMILES:
O=C(N1CCCC1)OC(C)(C)C
Properties
Properties
 
BP:
80°C at 0.2 mmHg  
Form:
Solid  
Refractive Index:
n20/D 1.449(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
166  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.6  

Literature

Title: Ambient temperature zincation of N-Boc pyrrolidine and its solvent dependency.

Journal: Chemical communications (Cambridge, England) 20120528

Title: Silyl fluoride electrophiles for the enantioselective synthesis of silylated pyrrolidine catalysts.

Journal: The Journal of organic chemistry 20110902

Title: Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.

Journal: The Journal of organic chemistry 20110805

Title: Asymmetric deprotonation using s-BuLi or i-PrLi and chiral diamines in THF: the diamine matters.

Journal: Journal of the American Chemical Society 20101103

Title: Regioselective and stereoselective copper(I)-promoted allylation and conjugate addition of N-Boc-2-lithiopyrrolidine and N-Boc-2-lithiopiperidine.

Journal: The Journal of organic chemistry 20100618

Title: Catalytic asymmetric synthesis of piperidines from pyrrolidine: concise synthesis of L-733,060.

Journal: Organic letters 20090507

Title: Solution-phase parallel synthesis of Hsp90 inhibitors.

Journal: Journal of combinatorial chemistry 20090101

Title: The first example of enamine-Lewis acid cooperative bifunctional catalysis: application to the asymmetric aldol reaction.

Journal: Chemical communications (Cambridge, England) 20080907

Title: On the two-ligand catalytic asymmetric deprotonation of N-boc pyrrolidine: probing the effect of the stoichiometric ligand.

Journal: The Journal of organic chemistry 20080815

Title: Enantioselective Pd-catalyzed alpha-arylation of N-Boc-pyrrolidine: the key to an efficient and practical synthesis of a glucokinase activator.

Journal: The Journal of organic chemistry 20080704

Title: A new sparteine surrogate for asymmetric deprotonation of N-Boc pyrrolidine.

Journal: Organic letters 20080403

Title: Asymmetric lithiation-substitution of amines involving rearrangement of borates.

Journal: Organic letters 20080103

Title: A (-)-sparteine-directed highly enantioselective synthesis of boroproline. Solid- and solution-state structure and properties.

Journal: The Journal of organic chemistry 20070803

Title: Dynamic thermodynamic and dynamic kinetic resolution of 2-lithiopyrrolidines.

Journal: Journal of the American Chemical Society 20060823

Title: Asymmetric synthesis of enantioenriched (+)-elaeokanine A.

Journal: The Journal of organic chemistry 20060721

Title: Reactivity series for s-BuLi/diamine-mediated lithiation of N-Boc pyrrolidine: applications in catalysis and lithiation of N-Boc piperidine.

Journal: Chemical communications (Cambridge, England) 20060628

Title: Enantioselective, palladium-catalyzed alpha-arylation of N-Boc-pyrrolidine.

Journal: Journal of the American Chemical Society 20060322

Title: Dynamic kinetic resolution of N-Boc-2-lithiopyrrolidine.

Journal: Chemical communications (Cambridge, England) 20050628

Title: Is the A-ring of sparteine essential for high enantioselectivity in the asymmetric lithiation-substitution of N-Boc-pyrrolidine?

Journal: Journal of the American Chemical Society 20041201

Title: An experimental and computational study of the enantioselective lithiation of N-Boc-pyrrolidine using sparteine-like chiral diamines.

Journal: Journal of the American Chemical Society 20041201

Title: Synthesis of (-)-(R)-pyrrolam a and studies on its stability: a caveat on computational methods.

Journal: The Journal of organic chemistry 20040903

Title: Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation-substitution of N-(tert-butoxycarbonyl)pyrrolidine.

Journal: Organic & biomolecular chemistry 20031121

Title: Conformational control of flexible molecules: design and synthesis of novel chiral 1,5-diaza-cis-decalins.

Journal: The Journal of organic chemistry 20020503

Title: An experimental and computational investigation of the enantioselective deprotonation of Boc-piperidine.

Journal: Journal of the American Chemical Society 20020306

Title: Chiral diamines 4: a computational study of the enantioselective deprotonation of Boc-pyrrolidine with an alkyllithium in the presence of a chiral diamine.

Journal: Journal of the American Chemical Society 20010829

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