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49845-33-2,MFCD00127867
Catalog No.:AA003FNS

49845-33-2 | 2,4-Dichloro-5-nitropyrimidine, tech grade

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
97% (contains ≤10%DCM)
in stock  
$6.00   $4.00
- +
10g
98%
in stock  
$10.00   $7.00
- +
25g
98%
in stock  
$25.00   $17.00
- +
100g
98%
in stock  
$72.00   $50.00
- +
500g
98%
in stock  
$358.00   $250.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003FNS
Chemical Name:
2,4-Dichloro-5-nitropyrimidine, tech grade
CAS Number:
49845-33-2
Molecular Formula:
C4HCl2N3O2
Molecular Weight:
193.9756
MDL Number:
MFCD00127867
SMILES:
Clc1ncc(c(n1)Cl)[N+](=O)[O-]
Properties
Properties
 
BP:
325.8°C at 760 mmHg  
Form:
Solid  
MP:
28-32 °C  
Refractive Index:
1.6100 (estimate)  
Stability:
Moisture Sensitive  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
162  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
XLogP3:
2  

Upstream Synthesis Route

[1]Patent:CN106432239,2017,A,.Locationinpatent:Paragraph0066;0071;0072

[2]JournalofHeterocyclicChemistry,2012,vol.49,#2,p.321-328

[3]TetrahedronLetters,2006,vol.47,#50,p.8897-8900

[4]Patent:WO2010/83645,2010,A1,.Locationinpatent:Page/Pagecolumn27

[5]Patent:US7256196,2007,B1,.Locationinpatent:Page/Pagecolumn8;9-10

[6]EuropeanJournalofMedicinalChemistry,2015,vol.95,p.29-34

[7]ChemischeBerichte,1906,vol.39,p.252

[8]JournaloftheChemicalSociety,1951,p.1565,1568

[9]JournaloftheChemicalSociety,1953,p.1646

[10]JournaloftheChemicalSociety,1951,p.474,478

[11]JournaloftheChemicalSociety,1952,p.4219,4224

[12]JournalofMedicinalChemistry,2004,vol.47,#1,p.240-253

[13]Patent:US2002/52375,2002,A1,

[14]Patent:WO2003/99809,2003,A1,.Locationinpatent:Page32

[15]Patent:WO2003/99231,2003,A2,.Locationinpatent:Page32

[16]Patent:WO2005/3099,2005,A2,.Locationinpatent:Page136-137

[17]Patent:WO2005/97162,2005,A2,.Locationinpatent:Page/Pagecolumn541;549;552-553

[18]TetrahedronLetters,2011,vol.52,#42,p.5521-5524

[19]Patent:US2015/266828,2015,A1,.Locationinpatent:Paragraph0313

[1]JournalofOrganicChemistry,2015,vol.80,#5,p.2676-2699

[2]JournalofChemicalResearch,Miniprint,1992,#2,p.514-539

[3]Patent:WO2009/155156,2009,A1,.Locationinpatent:Page/Pagecolumn77-78

[1]Patent:US6342503,2002,B1,.Locationinpatent:Example105

[1]Patent:US6342503,2002,B1,.Locationinpatent:Pagecolumn69-70

[1]ChemischeBerichte,1906,vol.39,p.252

Downstream Synthesis Route

[1]Patent:CN106432239,2017,A.Locationinpatent:Paragraph0066;0071;0072

[2]JournalofHeterocyclicChemistry,2012,vol.49,p.321-328

[3]TetrahedronLetters,2006,vol.47,p.8897-8900

[4]Patent:WO2010/83645,2010,A1.Locationinpatent:Page/Pagecolumn27

[5]ChemMedChem,2019,vol.14,p.952-964

[6]Patent:US7256196,2007,B1.Locationinpatent:Page/Pagecolumn8;9-10

[7]EuropeanJournalofMedicinalChemistry,2015,vol.95,p.29-34

[8]ChemischeBerichte,1906,vol.39,p.252

[9]JournaloftheChemicalSociety,1951,p.1565,1568    JournaloftheChemicalSociety,1953,p.1646

[10]JournaloftheChemicalSociety,1951,p.474,478    JournaloftheChemicalSociety,1952,p.4219,4224

[11]JournalofMedicinalChemistry,2004,vol.47,p.240-253

[12]Patent:US2002/52375,2002,A1

[13]Patent:WO2003/99809,2003,A1.Locationinpatent:Page32

[14]Patent:WO2003/99231,2003,A2.Locationinpatent:Page32

[15]Patent:WO2005/3099,2005,A2.Locationinpatent:Page136-137

[16]Patent:WO2005/97162,2005,A2.Locationinpatent:Page/Pagecolumn541;549;552-553

[17]TetrahedronLetters,2011,vol.52,p.5521-5524

[18]Patent:US2015/266828,2015,A1.Locationinpatent:Paragraph0313

[1]Patent:US2011/195980,2011,A1.Locationinpatent:Page/Pagecolumn17

[2]Patent:WO2011/106168,2011,A1.Locationinpatent:Page/Pagecolumn83;84;101;102

[3]JournaloftheChemicalSociety,1951,p.1565,1568    JournaloftheChemicalSociety,1953,p.1646

[4]Chemicalandpharmaceuticalbulletin,1958,vol.6,p.352,354

[5]Patent:CN103864792,2017,B.Locationinpatent:Paragraph0357;0358;0359;0360

[1]Patent:US2017/313683,2017,A1.Locationinpatent:Paragraph0541-0542

[2]JournalofMedicinalChemistry,2012,vol.55,p.10685-10699

[3]Patent:EP2578584,2013,A1.Locationinpatent:Paragraph0071;0072

[4]BioorganicChemistry,2020,vol.98

[5]BioorganicandMedicinalChemistry,2020,vol.28

[6]ChemMedChem,2019,vol.14,p.952-964

[7]JournalofHeterocyclicChemistry,2012,vol.49,p.321-328

[8]Patent:EP3284743,2018,A1.Locationinpatent:Paragraph0135

[9]ChemischeBerichte,1906,vol.39,p.252

[10]JournalofAppliedChemistry,1952,vol.2,p.239

[11]JournalofMedicinalChemistry,1992,vol.35,p.4455-4463

[12]Patent:US2005/250779,2005,A1.Locationinpatent:Page/Pagecolumn5

[13]Patent:US2007/72862,2007,A1.Locationinpatent:Page/Pagecolumn83-84

[14]Patent:US2012/172347,2012,A1.Locationinpatent:Page/Pagecolumn35

[1]ChemischeBerichte,1906,vol.39,p.252

[2]JournaloftheChemicalSociety,1951,p.474,478    JournaloftheChemicalSociety,1952,p.4219,4224

[3]JournalofMedicinalChemistry,2004,vol.47,p.240-253

574-66-3    49845-33-2    611-08-5   
2,4-bis-diphenyliminoxy-5-nitropyrimidine 

[1]SyntheticCommunications,1985,vol.15,p.171-178

Literature

Title: Probing cell-division phenotype space and Polo-like kinase function using small molecules.

Journal: Nature chemical biology 20061101

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