Home Amines 77815-14-6
77815-14-6,MFCD01086598
Catalog No.:AA003GBD

77815-14-6 | 2-Amino-4-(4-fluorophenyl)thiazole

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Purity
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1g
98%
in stock  
$23.00   $16.00
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5g
98%
in stock  
$103.00   $72.00
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10g
95%
in stock  
$173.00   $121.00
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25g
95%
in stock  
$344.00   $241.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003GBD
Chemical Name:
2-Amino-4-(4-fluorophenyl)thiazole
CAS Number:
77815-14-6
Molecular Formula:
C9H7FN2S
Molecular Weight:
194.2287
MDL Number:
MFCD01086598
SMILES:
Fc1ccc(cc1)c1csc(n1)N
Properties
Properties
 
BP:
359.1°C at 760 mmHg  
Form:
Solid  
MP:
102-110 °C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
171  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.7  

Downstream Synthesis Route

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[2]Siddiqui,HamidLatif;Iqbal,Amjid;Ahmad,Saeed;Weaver,GeorgeW.[Molecules,2006,vol.11,#2-3,p.206-211]

[3]Keshari,Twinkle;Kapoorr,Ritu;Yadav,LalDharS.[TetrahedronLetters,2015,vol.56,#41,p.5623-5627]

[4]Ge,Lingqing;Hu,Qiaozhen;Shi,Mengrao;Yang,Huiyun;Zhu,Guoji[RSCAdvances,2017,vol.7,#52,p.32909-32922]

[5]Koppireddi,Satish;Komsani,JayaramReddy;Avula,Sreenivas;Pombala,Sujitha;Vasamsetti,Satishbabu;Kotamraju,Srigiridhar;Yadla,Rambabu[EuropeanJournalofMedicinalChemistry,2013,vol.66,p.305-313]

[6]Alagarsamy;Senthilraja;RajaSolomon[JournalofHeterocyclicChemistry,2016,vol.53,#5,p.1635-1639]

[7]Zitko,Jan;Jand'Ourek,Ondřej;Paterová,Pavla;Navrátilová,Lucie;Kuneš,Jiří;Vinšová,Jarmila;Doležal,Martin[MedChemComm,2018,vol.9,#4,p.685-696]

[8]Ujwaldev,SankuviruthiyilM.;Harry,NissyAnn;Neetha,Mohan;Anilkumar,Gopinathan[JournalofHeterocyclicChemistry,2021,vol.58,#2,p.646-653]

[9]Zhang,Qian;Wu,Jiefei;Pan,Zexi;Zhang,Wen;Zhou,Wei[JournalofChemicalResearch,2021,vol.45,#1-2,p.89-94]

[10]CurrentPatentAssignee:ZHEJIANGUNIVERSITYOFTECHNOLOGY-CN110845437,2020,ALocationinpatent:Paragraph0030-0035;0126-0129

[11]Joshi,K.C.;Bahel,S.C.[JournaloftheIndianChemicalSociety,1962,vol.39,p.121-128]Bhargava;Lakhan;Tripathi[JournaloftheIndianChemicalSociety,1982,vol.59,#6,p.773-775]

[12]Cousse;Mouzin;Bonnaud;Tarayre;Couzinier[Arzneimittel-Forschung/DrugResearch,1986,vol.36,#9,p.1391-1393]

[13]Locationinpatent:experimentalpartMore;Lawand;Dalave;Nalawade[JournaloftheIndianChemicalSociety,2008,vol.85,#8,p.862-865]

[14]Locationinpatent:schemeortableThumar,NileshJ.;Patel,ManishP.[ArchivderPharmazie,2011,vol.344,#2,p.91-101]

[15]Thumar,NileshJ.;Patel,ManishP.[JournalofHeterocyclicChemistry,2012,vol.49,#5,p.1169-1178]

[16]Joshi,ShrinivasD.;More,UttamA.;Dixit,SheshagiriR.;Korat,HareshH.;Aminabhavi,TejrajM.;Badiger,AravindM.[MedicinalChemistryResearch,2014,vol.23,#3,p.1123-1147]

[17]Koppireddi,Satish;Chilaka,DeepikaRajKumari;Avula,Sreenivas;Komsani,JayaramReddy;Kotamraju,Srigiridhar;Yadla,Rambabu[BioorganicandMedicinalChemistryLetters,2014,vol.24,#23,p.5428-5431]

[18]Zhao,Gang;Lan,Dengzhe;Qi,Guobao[ChemicalBiologyandDrugDesign,2017,vol.90,#5,p.778-790]

[19]Wang,Xiwen;Yi,Yuexiong;Lv,Qiongying;Zhang,Juan;Wu,Kejia;Wu,Wanrong;Zhang,Wei[ChemicalBiologyandDrugDesign,2018,vol.91,#3,p.728-734]

[20]Chen,Lingfeng;Chen,Hongjin;Chen,Pengqin;Zhang,Wenxin;Wu,Chao;Sun,Chuchu;Luo,Wu;Zheng,Lulu;Liu,Zhiguo;Liang,Guang[EuropeanJournalofMedicinalChemistry,2019,vol.161,p.22-38]

[21]Monga,Vikramdeep;Singh,Hargyan;Singh,Gurpreet[IndianJournalofHeterocyclicChemistry,2017,vol.27,#1,p.51-57]

[22]GobalaKrishnan;Gnanaprakash;Chandrasekhar[InternationalJournalofResearchinPharmaceuticalSciences,2019,vol.10,#2,p.1504-1509]

[23]Poola,Sreelakshmi;Gundluru,Mohan;Nadiveedhi,MaheshwaraReddy;Saddala,MadhuSudhana;P.T.S.R.K,PrasadaRao;Cirandur,SureshReddy[Phosphorus,SulfurandSiliconandtheRelatedElements,2020,vol.195,#5,p.409-420]

[1]Khillare,LalitD.;Pratap,UmeshR.;Bhosle,ManishaR.;Dhumal,SambhajiT.;Bhalerao,MahendraB.;Mane,RamraoA.[ResearchonChemicalIntermediates,2017,vol.43,#8,p.4327-4337]

[2]Walchshofer;Minjat;Tinland;etal.[EuropeanJournalofMedicinalChemistry,1986,vol.21,#1,p.59-64]

[1]Patent:WO2008/101029,2008,A2.Locationinpatent:Page/Pagecolumn83;84

[1]Patent:WO2008/101029,2008,A2.Locationinpatent:Page/Pagecolumn86;87

[1]CurrentPatentAssignee:XENONPHARMACEUTICALSINC-WO2008/101029,2008,A2Locationinpatent:Page/Pagecolumn92;93

Literature

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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Tags:77815-14-6 Molecular Formula|77815-14-6 MDL|77815-14-6 SMILES|77815-14-6 2-Amino-4-(4-fluorophenyl)thiazole