Home Amines 695-34-1
695-34-1,MFCD00006321
Catalog No.:AA003GCS

695-34-1 | 2-Amino-4-methylpyridine

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  • Technical Information
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Technical Information
Catalog Number:
AA003GCS
Chemical Name:
2-Amino-4-methylpyridine
CAS Number:
695-34-1
Molecular Formula:
C6H8N2
Molecular Weight:
108.1411
MDL Number:
MFCD00006321
SMILES:
Cc1ccnc(c1)N
Properties
Properties
 
BP:
227.4°C at 760 mmHg  
Form:
Solid  
MP:
96-101 °C  
Refractive Index:
1.5560 (estimate)  
Solubility:
DMF: freely soluble  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
72.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
0.6  

Literature

Title: Molecular and crystal structures, vibrational studies and quantum chemical calculations of 3 and 5-nitroderivatives of 2-amino-4-methylpyridine.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

Title: Di-μ-chlorido-bis-[(2-amino-4-methyl-pyridine-κN)-chloridomercury(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20121001

Title: Feasibility and dosimetry studies for 18F-NOS as a potential PET radiopharmaceutical for inducible nitric oxide synthase in humans.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120601

Title: Supramolecular assembled of hexameric water clusters into a 1D chain containing (H2O)6 and [(H2O)4O2] stabilized by hydrogen bonding in a copper complex.

Journal: Chemistry Central journal 20120101

Title: Tris(1,10-phenanthroline-κN,N')nickel(II) dinitrate tetra-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: 2,3-Diamino-pyridinium 6-carb-oxy-pyridine-2-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Growth and characterization of 2-amino-4-picolinium toluene sulfonate single crystal.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

Title: Tetra-kis(2-amino-4-methyl-pyridinium) cyclo-tetra-μ(2)-oxido-tetra-kis-[dioxido-vanadate(V)] tetra-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: N,N-Dimethyl-propane-1,2-diaminium bis-(6-carb-oxy-pyridine-2-carboxyl-ate) monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: Bis(2-amino-4-methyl-pyridinium) bis-(pyridine-2,6-dicarboxyl-ato)cuprate(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: 2-Amino-4-methyl-pyridinium 6-carb-oxy-pyridine-2-carboxyl-ate methanol monosolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: 2-Amino-4-methyl-pyridinium 6-carb-oxy-pyridine-2-carboxyl-ate sesquihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Bis(2-amino-5-bromo-pyridinium) fumarate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: 2-Amino-4-methyl-pyridinium hexa-2,4-dienoate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: 4-Methyl-N-[(E)-4-methyl-1-(4-methyl-phenyl-sulfon-yl)-1,2-dihydropyridin-2-yl-idene]benzene-sulfonamide.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Bis(2-amino-4-methyl-pyridinium) terephthalate tetra-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: 2-Amino-4-methyl-pyridinium 2-carb-oxy-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: 2-Amino-4-methylpyridinium 2-hy-droxy-3,5-dinitro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: 2-Amino-4-methyl-pyridinium (E)-3-carb-oxy-prop-2-enoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: 2-Amino-4-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: 2-Amino-4-methyl-pyridinium 2-hy-droxy-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide.

Journal: Cardiovascular research 20100715

Title: Bis(2-amino-4-methyl-pyridinium) trans-diaqua-bis-(pyrazine-2,3-dicarboxyl-ato)cuprate(II) hexa-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: 2-Amino-4-methyl-pyridinium 3-chloro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: DNA binding ability and hydrogen peroxide induced nuclease activity of a novel Cu(II) complex with malonate as the primary ligand and protonated 2-amino-4-picoline as the counterion.

Journal: The journal of physical chemistry. B 20100506

Title: Dimethyl 4-eth-oxy-1-(4-methyl-2-pyri-dyl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3-dicarboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Supramolecular assembly of Mg(II) complexes directed by associative lone pair-pi/pi-pi/pi-anion-pi/pi-lone pair interactions.

Journal: The journal of physical chemistry. B 20100422

Title: Growth and characterization of 2-amino-4-picolinium 4-aminobenzoate single crystals.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100401

Title: 2-Amino-4-methyl-pyridinium trifluoro-acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: 2-Amino-4-methyl-pyridinium trifluoro-acetate: a monoclinic polymorph.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Quantitative morphometry of respiratory tract epithelial cells as a tool for testing chemopreventive agent efficacy.

Journal: Anticancer research 20100301

Title: 2-Amino-5-methyl-pyridinium 4-nitro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100301

Title: 2-Amino-4-methyl-pyridinium 4-nitro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20100201

Title: Robust recognition of malonate and 2-amino-4-picolinium in conjunction with M(II) as a triad (M = Ni/Co/Mn): role of this highly stable hydrogen-bonded motif in driving supramolecular self-assembly.

Journal: Dalton transactions (Cambridge, England : 2003) 20091007

Title: Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.

Journal: European journal of medicinal chemistry 20090701

Title: 4-Methyl-3-nitro-pyridin-2-amine.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase.

Journal: Journal of medicinal chemistry 20090423

Title: 2-Ferrocenyl-N-(2-ferrocenylbenzo-yl)-N-(4-methyl-2-pyrid-yl)benzamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: Bis(2-amino-4-methyl-pyridinium) tetra-chloridocuprate(II).

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: Rhodium(I)-catalyzed one-pot synthesis of dialkyl ketones from methanol and alkenes through directed sp3 C-H bond activation of N-methylamine.

Journal: Chemical communications (Cambridge, England) 20081130

Title: tert-Butyl N-(4-methyl-2-pyrid-yl)-carbamate.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Hexakis(2-amino-4-methyl-pyridine-κN)dioxidohexa-μ(4)-sulfido-hexa-copper(I)divanadium(V).

Journal: Acta crystallographica. Section E, Structure reports online 20080901

Title: 2-Amino-4-methyl-pyridinium 4-amino-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.

Journal: Bioorganic & medicinal chemistry letters 20060915

Title: Cd(II), Zn(II), and Pd(II) complexes of an isoindoline pincer ligand: consequences of steric crowding.

Journal: Inorganic chemistry 20050905

Title: The fixation of bis(2-pyridylimino)isoindolato (BPI) ligands to dendritic carbosilanes.

Journal: Dalton transactions (Cambridge, England : 2003) 20050421

Title: 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution.

Journal: Journal of medicinal chemistry 20040603

Title: Structure-activity relationships of potent, selective inhibitors of neuronal nitric oxide synthase based on the 6-phenyl-2-aminopyridine structure.

Journal: Journal of medicinal chemistry 20040311

Title: Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system.

Journal: Neoplasia (New York, N.Y.) 20020701

Title: Synthesis of aliphatic ketones from allylic alcohols through consecutive isomerization and chelation-assisted hydroacylation by a rhodium catalyst.

Journal: The Journal of organic chemistry 20020531

Title: Inhibition of nitric oxide synthase aggravates cisplatin-induced nephrotoxicity: effect of 2-amino-4-methylpyridine.

Journal: Chemotherapy 20020101

Title: 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo.

Journal: British journal of pharmacology 19961101

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