Home Iodos 615-43-0
615-43-0,MFCD00007680
Catalog No.:AA003HDX

615-43-0 | 2-Iodoaniline

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5g
98%
in stock  
$9.00   $6.00
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10g
98% GC
in stock  
$12.00   $8.00
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25g
98%
in stock  
$19.00   $13.00
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100g
98%
in stock  
$48.00   $33.00
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500g
98%
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$235.00   $164.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003HDX
Chemical Name:
2-Iodoaniline
CAS Number:
615-43-0
Molecular Formula:
C6H6IN
Molecular Weight:
219.0230
MDL Number:
MFCD00007680
SMILES:
Nc1ccccc1I
NSC Number:
34544
Properties
Properties
 
Form:
Solid  
MP:
55-58 °C(lit.)  
Stability:
Light Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
74.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
XLogP3:
2.3  

Downstream Synthesis Route

[1]Patent:US2005/239768,2005,A1.Locationinpatent:Page/Pagecolumn12

[2]Patent:WO2016/170009,2016,A1.Locationinpatent:Page/Pagecolumn76

[3]EuropeanJournalofMedicinalChemistry,2014,vol.83,p.274-283

[4]JournalofMedicinalChemistry,1988,vol.31,p.1712-1719

[1]Tetrahedron,2016,vol.72,p.653-657

[2]Synlett,2011,p.623-626

[3]Patent:WO2013/120104,2013,A2.Locationinpatent:Paragraph00334

[4]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.3644-3649

[5]Synthesis,1984,p.616-617

[1]JournalofOrganometallicChemistry,2013,vol.741-742,p.162-167

[2]RSCAdvances,2018,vol.8,p.11324-11329

[3]RSCAdvances,2013,vol.3,p.18345-18350

[4]JournalofOrganometallicChemistry,2014,vol.765,p.31-38

[5]EuropeanJournalofOrganicChemistry,2012,p.4380-4386

[6]RSCAdvances,2014,vol.4,p.4921-4929

[7]AdvancedSynthesisandCatalysis,2009,vol.351,p.2055-2062

[8]OrganicandBiomolecularChemistry,2010,vol.8,p.3338-3342

[9]AdvancedSynthesisandCatalysis,2002,vol.344,p.172-183

[10]TetrahedronLetters,1998,vol.39,p.8317-8320

[11]BioorganicandMedicinalChemistryLetters,2016,vol.26,p.2119-2123

[1]Synthesis,1999,p.2053-2056

[1]JournaloftheAmericanChemicalSociety,2004,vol.126,p.3529-3533

Literature

Title: Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with the Michael acceptor, diethyl ethoxycarbonylbutendienoate.

Journal: The Journal of organic chemistry 20120504

Title: N-(2-Iodo-phen-yl)benzene-carbox-imid-amide.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Quinol derivatives as potential trypanocidal agents.

Journal: Bioorganic & medicinal chemistry 20120215

Title: N-[2-(N-Cyclo-hexyl-carbamo-yl)propan-2-yl]-N-(2-iodo-phen-yl)prop-2-ynamide.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Synthesis of δ-carbolines via a Pd-catalyzed sequential reaction from 2-iodoanilines and N-tosyl-enynamines.

Journal: Organic letters 20120106

Title: Pd-carbene catalyzed carbonylation reactions of aryl iodides.

Journal: Dalton transactions (Cambridge, England : 2003) 20110807

Title: A protocol to 2-aminobenzimidazoles via copper-catalyzed cascade addition and cyclization of o-haloanilines and carbodiimides.

Journal: The Journal of organic chemistry 20110506

Title: Transition-metal-free O-, S-, and N-arylation of alcohols, thiols, amides, amines, and related heterocycles.

Journal: The Journal of organic chemistry 20110121

Title: Synthesis of dibenzazepinones by palladium-catalyzed intramolecular arylation of o-(2'-bromophenyl)anilide enolates.

Journal: The Journal of organic chemistry 20101001

Title: Palladium on carbon-catalyzed synthesis of 2- and 2,3-substituted indoles under heterogeneous conditions.

Journal: Organic & biomolecular chemistry 20100721

Title: Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: psychotrimine and kapakahines B and F.

Journal: Journal of the American Chemical Society 20100526

Title: Microwave-assisted carbonylation and cyclocarbonylation of aryl iodides under ligand free heterogeneous catalysis.

Journal: The Journal of organic chemistry 20100319

Title: Much improved conditions for the Negishi cross-coupling of iodoalanine derived zinc reagents with aryl halides.

Journal: The Journal of organic chemistry 20100101

Title: 4-Bromo-2-chloro-aniline.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: A straightforward synthesis of benzothiazines.

Journal: Organic letters 20090115

Title: Synthesis of 2-aminobenzothiazole via copper(I)-catalyzed tandem reaction of 2-iodobenzenamine with isothiocyanate.

Journal: Journal of combinatorial chemistry 20090101

Title: 2-Chloro-4-iodo-aniline.

Journal: Acta crystallographica. Section E, Structure reports online 20081201

Title: Total synthesis of (+/-)-psychotrimine.

Journal: Journal of the American Chemical Society 20080820

Title: Regioselectivity of Larock indole synthesis using functionalized alkynes.

Journal: Bioscience, biotechnology, and biochemistry 20080801

Title: Palladium(II) complexes of unsymmetrical CNN pincer ligands.

Journal: Inorganic chemistry 20080721

Title: Synthesis of meso-5-azaindolyl-appended Zn(II) porphyrins via Pd-catalyzed annulation.

Journal: Organic letters 20070621

Title: Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions.

Journal: Journal of medicinal chemistry 20070405

Title: Palladium-catalyzed, modular synthesis of highly functionalized indoles and tryptophans by direct annulation of substituted o-haloanilines and aldehydes.

Journal: The Journal of organic chemistry 20060929

Title: Facile preparation and reactivity of polymer-supported N-(2-Iodyl-phenyl)-acylamide, an efficient oxidizing system.

Journal: Organic letters 20060105

Title: A facile regiocontrol in the palladium-catalyzed annulation of fluorine-containing internal alkynes with variously substituted 2-iodoanilines: a new regioselective synthesis of 2- or 3-fluoroalkylated indole derivatives.

Journal: The Journal of organic chemistry 20041126

Title: Syntheses of 2-substituted indoles and fused indoles by photostimulated reactions of o-iodoanilines with carbanions by the SRN1 mechanism.

Journal: The Journal of organic chemistry 20030404

Title: Concise synthesis of (+/-)-horsfiline and (+/-)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides.

Journal: Organic & biomolecular chemistry 20030107

Title: Synthesis of novel alpha-C-glycosylamino acids and reverse regioselectivity in Larock's heteroannulation for the synthesis of the indole nucleus.

Journal: Bioscience, biotechnology, and biochemistry 20021001

Title: First syntheses of two quinoline alkaloids from the medicinal herb Ruta chalepensis via cyclization of an o-iodoaniline with an acetylenic sulfone.

Journal: Chemical communications (Cambridge, England) 20020821

Title: Preparation of polyfunctional heterocycles using highly functionalized aminated arylmagnesium reagents as versatile scaffolds.

Journal: Organic letters 20020530

Title: Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay.

Journal: Biochemistry 20020122

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