+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Carboxes 21211-22-3
21211-22-3,MFCD00014579
Catalog No.:AA003J7O

21211-22-3 | 3-Chlorobenzo[b]thiophene-2-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$19.00   $14.00
- +
5g
98%
in stock  
$66.00   $47.00
- +
10g
98%
in stock  
$127.00   $89.00
- +
25g
98%
in stock  
$246.00   $172.00
- +
100g
98%
in stock  
$854.00   $598.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003J7O
Chemical Name:
3-Chlorobenzo[b]thiophene-2-carboxylic acid
CAS Number:
21211-22-3
Molecular Formula:
C9H5ClO2S
Molecular Weight:
212.6528
MDL Number:
MFCD00014579
SMILES:
OC(=O)c1sc2c(c1Cl)cccc2
NSC Number:
206632
Properties
Properties
 
BP:
395.1 °C at 760 mmHg  
Form:
Solid  
MP:
268-272 °C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
222  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
3.4  

Downstream Synthesis Route

[1]Sidorenko,T.N.;Terent'eva,G.A.;Raida,V.S.;Andrienko,O.S.;Savinykh,Yu.V.;Aksenov,V.S.[ChemistryofHeterocyclicCompounds,1982,vol.18,#12,p.1246-1250][KhimiyaGeterotsiklicheskikhSoedinenii,1982,vol.18,#12,p.1618-1622]

[2]Zhang,Yun;Jamison,TimothyF.;Patel,Sejal;Mainolfi,Nello[OrganicLetters,2011,vol.13,#2,p.280-283]

[3]Li,Zhaojie;Fu,Zhengjiang;Zhang,Haixia;Long,Jiao;Song,Yuanyuan;Cai,Hu[NewJournalofChemistry,2016,vol.40,#4,p.3014-3018]

[4]Kuriyama,Masami;Hamaguchi,Norihisa;Yano,Gemba;Tsukuda,Kotaro;Sato,Kanako;Onomura,Osamu[JournalofOrganicChemistry,2016,vol.81,#19,p.8934-8946]

[5]Tilstam,Ulf[OrganicProcessResearchandDevelopment,2012,vol.16,#8,p.1449-1454]

21211-22-3    94790-37-1   
3-chloro-benzo<i>b</i>thiophene-2-carboxylicacidbenzotriazol-1-ylester 

[1]BioorganicandMedicinalChemistryLetters,2004,vol.14,p.1253-1257

[1]Fedi,Valentina;Altamura,Maria;Catalioto,Rose-Marie;Giannotti,Danilo;Giolitti,Alessandro;Giuliani,Sandro;Guidi,Antonio;Harmat,NicholasJ.S.;Lecci,Alessandro;Meini,Stefania;Nannicini,Rossano;Pasqui,Franco;Tramontana,Manuela;Triolo,Antonio;Maggi,CarloAlberto[JournalofMedicinalChemistry,2007,vol.50,#20,p.4793-4807]

[1]Fedi,Valentina;Altamura,Maria;Catalioto,Rose-Marie;Giannotti,Danilo;Giolitti,Alessandro;Giuliani,Sandro;Guidi,Antonio;Harmat,NicholasJ.S.;Lecci,Alessandro;Meini,Stefania;Nannicini,Rossano;Pasqui,Franco;Tramontana,Manuela;Triolo,Antonio;Maggi,CarloAlberto[JournalofMedicinalChemistry,2007,vol.50,#20,p.4793-4807]

[2]Locationinpatent:experimentalpartFuchs,FerdinandC.;Eller,GernotA.;Holzer,Wolfgang[Molecules,2009,vol.14,#9,p.3814-3832]

[3]CurrentPatentAssignee:THEUNIVERSITYOFTEXASSYSTEM-WO2015/35051,2015,A1Locationinpatent:Page/Pagecolumn175

[4]CurrentPatentAssignee:NONO-US9334256,2016,B2Locationinpatent:Page/Pagecolumn88

[5]CurrentPatentAssignee:KOREARESEARCHINSTITUTEOFCHEMICALTECHNOLOGY-KR2016/21163,2016,ALocationinpatent:Paragraph0482;0484

[6]CurrentPatentAssignee:KOREARESEARCHINSTITUTEOFCHEMICALTECHNOLOGY-KR2015/25531,2015,ALocationinpatent:Paragraph0482;0483;0484

[7]CurrentPatentAssignee:CHINESEACADEMYOFMEDICALSCIENCES-CN105130978,2017,BLocationinpatent:Paragraph0025

[8]Li,Lingzi;Ndzeidze,GilbertN.;Steinmetz,MarkG.[Tetrahedron,2019,vol.75,#1,p.70-83]

Literature

Title: Potent agonists of the Hedgehog signaling pathway.

Journal: Bioorganic & medicinal chemistry letters 20090801

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 21211-22-3
124168-55-4

124168-55-4

 13771-75-0

13771-75-0

 14006-54-3

14006-54-3

 26018-73-5

26018-73-5

 310390-60-4

310390-60-4

 34576-92-6

34576-92-6
Building Blocks
More >
Tags:21211-22-3 Molecular Formula|21211-22-3 MDL|21211-22-3 SMILES|21211-22-3 3-Chlorobenzo[b]thiophene-2-carboxylic acid |Organic_Building_Blocks