Title: Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121101
Title: Single dose NTBC-treatment of hereditary tyrosinemia type I.
Journal: Journal of inherited metabolic disease 20120901
Title: Evaluation of a novel, commercially available mass spectrometry kit for newborn screening including succinylacetone without hydrazine.
Journal: Clinica chimica acta; international journal of clinical chemistry 20120816
Title: Evaluation of factors influencing accuracy in the analysis of succinylacetone in dried blood spots.
Journal: Clinica chimica acta; international journal of clinical chemistry 20120816
Title: Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Journal: Journal of medicinal chemistry 20120726
Title: Dried blood spot analysis by digital microfluidics coupled to nanoelectrospray ionization mass spectrometry.
Journal: Analytical chemistry 20120417
Title: [Application of succinylacetone levels measurement in the blood and urine in the diagnosis of tyrosinemia type 1].
Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20120201
Title: LC-MS/MS method for simultaneous determination on a dried blood spot of multiple analytes relevant for treatment monitoring in patients with tyrosinemia type I.
Journal: Analytical chemistry 20120117
Title: The stability of markers in dried-blood spots for recommended newborn screening disorders in the United States.
Journal: Clinical biochemistry 20111201
Title: Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma.
Journal: Molecular oncology 20111001
Title: Long-term outcome of living donor liver transplantation in a Thai boy with hereditary tyrosinemia type I: a case report.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20111001
Title: Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.
Journal: The Journal of biological chemistry 20110729
Title: Newborn screening for Tyr-I: two years' experience of the New York State program.
Journal: Molecular genetics and metabolism 20110601
Title: Improved tandem mass spectrometry (MS/MS) derivatized method for the detection of tyrosinemia type I, amino acids and acylcarnitine disorders using a single extraction process.
Journal: Clinica chimica acta; international journal of clinical chemistry 20110512
Title: Nonactin biosynthesis: unexpected patterns of label incorporation from 4,6-dioxoheptanoate show evidence of a degradation pathway for levulinate through propionate in Streptomyces griseus.
Journal: Journal of natural products 20101227
Title: Hereditary tyrosinemia type 1 metabolites impair DNA excision repair pathways.
Journal: Biochemical and biophysical research communications 20101008
Title: Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential.
Journal: The Journal of biological chemistry 20100716
Title: Clinical practice. NTBC therapy for tyrosinemia type 1: how much is enough?
Journal: European journal of pediatrics 20100601
Title: skn-1-Dependent and -independent regulation of aip-1 expression following metabolic stress in Caenorhabditis elegans.
Journal: Molecular and cellular biology 20100601
Title: Assessing the DNA methylation status of single cells with the comet assay.
Journal: Analytical biochemistry 20100515
Title: Significant increase of succinylacetone within the first 12 h of life in hereditary tyrosinemia type 1.
Journal: European journal of pediatrics 20100501
Title: Identification of a neonate with hepatorenal tyrosinemia by combined routine newborn screening for succinylacetone, acylcarnitines and amino acids.
Journal: Clinical biochemistry 20100501
Title: Lack of hemodynamic effects after extended heme synthesis inhibition by succinylacetone in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20100401
Title: Preliminary proficiency testing results for succinylacetone in dried blood spots for newborn screening for tyrosinemia type I.
Journal: Clinical chemistry 20091201
Title: The successful inclusion of succinylacetone as a marker of tyrosinemia type I in Tuscany newborn screening program.
Journal: Rapid communications in mass spectrometry : RCM 20091201
Title: Solution structure of succinylacetone, an unsymmetrical beta-diketone, as studied by 13C NMR and GIAO-DFT calculations.
Journal: The Journal of organic chemistry 20091120
Title: 2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.
Journal: Bioorganic & medicinal chemistry letters 20091101
Title: Improved MS/MS analysis of succinylacetone extracted from dried blood spots when combined with amino acids and acylcarnitine butyl esters.
Journal: Clinica chimica acta; international journal of clinical chemistry 20090901
Title: Post-transcriptional regulation of the expression of ferrochelatase by its variant mRNA.
Journal: Journal of biochemistry 20090601
Title: Clinical, biochemical, and genetic analysis of a Korean neonate with hereditary tyrosinemia type 1.
Journal: Clinical chemistry and laboratory medicine 20090101
Title: A novel mutation causing mild, atypical fumarylacetoacetase deficiency (Tyrosinemia type I): a case report.
Journal: Orphanet journal of rare diseases 20090101
Title: Improved method to determine succinylacetone in dried blood spots for diagnosis of tyrosinemia type 1 using UPLC-MS/MS.
Journal: Biomedical chromatography : BMC 20081101
Title: Acute depletion of heme by succinylacetone alters vascular responses but does not induce hypertension.
Journal: Canadian journal of physiology and pharmacology 20080901
Title: The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities.
Journal: Toxicology and applied pharmacology 20080615
Title: Combined newborn screening for succinylacetone, amino acids, and acylcarnitines in dried blood spots.
Journal: Clinical chemistry 20080401
Title: Enhancing newborn screening for tyrosinemia type I.
Journal: Clinical chemistry 20080401
Title: The inclusion of succinylacetone as marker for tyrosinemia type I in expanded newborn screening programs.
Journal: Rapid communications in mass spectrometry : RCM 20080101
Title: Tandem mass spectrometric determination of succinylacetone in dried blood spots enables presymptomatic detection in a case of hepatorenal tyrosinaemia.
Journal: Journal of inherited metabolic disease 20070801
Title: Analysis of succinylacetone, as a Girard T derivative, in urine and dried bloodspots by flow injection electrospray ionization tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: Porphobilinogen synthase from the butterfly, Pieris brassicae: purification and comparative characterization.
Journal: Journal of insect science (Online) 20070101
Title: Increased mutant frequencies in the HPRT gene locus of leukemia HL-60 cells treated with succinylacetone.
Journal: Cell biology and toxicology 20060901
Title: A GC-MS/MS method for the quantitative analysis of low levels of the tyrosine metabolites maleylacetone, succinylacetone, and the tyrosine metabolism inhibitor dichloroacetate in biological fluids and tissues.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606
Title: Quantitative determination of succinylacetone in dried blood spots for newborn screening of tyrosinemia type I.
Journal: Molecular genetics and metabolism 20060501
Title: Quantification of succinylacetone in urine of hepatorenal tyrosinemia patients by HPLC with fluorescence detection.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060301
Title: Newborn screening for hepatorenal tyrosinemia: Tandem mass spectrometric quantification of succinylacetone.
Journal: Clinical chemistry 20060301
Title: A GC/MS validated method for the nanomolar range determination of succinylacetone in amniotic fluid and plasma: an analytical tool for tyrosinemia type I.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217
Title: Determination of succinylacetone in dried blood spots and liquid urine as a dansylhydrazone by liquid chromatography tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202
Title: Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH.
Journal: The Biochemical journal 20051115
Title: Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death.
Journal: Brain research. Molecular brain research 20050613
Title: Determination of urinary succinylacetone by capillary electrophoresis for the diagnosis of tyrosinemia type I.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425
Title: Tandem mass spectrometric assay of succinylacetone in urine for the diagnosis of hepatorenal tyrosinemia.
Journal: Analytical biochemistry 20050415
Title: Renal function in tyrosinaemia type I after liver transplantation: a long-term follow-up.
Journal: Journal of inherited metabolic disease 20050101
Title: Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells.
Journal: Biochemical and biophysical research communications 20041105
Title: Newborn screening for hepatorenal tyrosinemia by tandem mass spectrometry: analysis of succinylacetone extracted from dried blood spots.
Journal: Clinical biochemistry 20041101
Title: Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases.
Journal: The American journal of pathology 20040801
Title: Heme deficiency causes apoptosis but does not increase ROS generation in HeLa cells.
Journal: Biochemical and biophysical research communications 20040709
Title: Succinylacetone oxidation by oxygen/peroxynitrite: a possible source of reactive intermediates in hereditary tyrosinemia type I.
Journal: Chemical research in toxicology 20040501
Title: Heme controls the expression of cell cycle regulators and cell growth in HeLa cells.
Journal: Biochemical and biophysical research communications 20040312
Title: Delta-aminolevulinic acid dehydratase from Plasmodium falciparum: indigenous versus imported.
Journal: The Journal of biological chemistry 20040220
Title: Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.
Journal: The Journal of biological chemistry 20040213
Title: Synthesis and immunosuppressive activity of novel succinylacetone analogues.
Journal: Archives of pharmacal research 20030301
Title: CYP2E1 overexpression up-regulates both non-specific delta-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1.
Journal: International journal of molecular medicine 20030101
Title: The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2.
Journal: Blood cells, molecules & diseases 20030101
Title: Heme deficiency interferes with the Ras-mitogen-activated protein kinase signaling pathway and expression of a subset of neuronal genes.
Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020901
Title: An examination of heme action in gene expression: heme and heme deficiency affect the expression of diverse genes in erythroid k562 and neuronal PC12 cells.
Journal: DNA and cell biology 20020401
Title: The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors.
Journal: Journal of molecular biology 20010907
Title: Spectrophotometric microassay for delta-aminolevulinate dehydratase in dried-blood spots as confirmation for hereditary tyrosinemia type I.
Journal: Clinical chemistry 20010801
Title: [Liver failure with coagulopathy in an infant with tyrosinemia].
Journal: Harefuah 20010701
Title: Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20010601
Title: Heme biosynthesis and oogenesis in the blood-sucking bug, Rhodnius prolixus.
Journal: Insect biochemistry and molecular biology 20010315
Title: Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis.
Journal: Biochimica et biophysica acta 20000227
Title: Hypoxic regulation of endothelial glyceraldehyde-3-phosphate dehydrogenase.
Journal: The American journal of physiology 19980201
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