773-76-2,MFCD00006786
Catalog No.:AA003M7V

773-76-2 | 5,7-Dichloroquinolin-8-ol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
98%
in stock  
$24.00   $17.00
- +
25g
98%
in stock  
$43.00   $30.00
- +
100g
98%
in stock  
$162.00   $114.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003M7V
Chemical Name:
5,7-Dichloroquinolin-8-ol
CAS Number:
773-76-2
Molecular Formula:
C9H5Cl2NO
Molecular Weight:
214.0481
MDL Number:
MFCD00006786
SMILES:
Clc1cc(Cl)c2c(c1O)nccc2
Properties
Properties
 
BP:
354.7 °C at 760 mmHg  
Form:
Solid  
MP:
178-180 °C(lit.)  
Refractive Index:
1.5500 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
191  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
0  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.5  

Literature

Title: Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.

Journal: Journal of medicinal chemistry 20130328

Title: Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode.

Journal: Journal of fluorescence 20120901

Title: Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

Journal: Journal of medicinal chemistry 20110811

Title: Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Journal: Nature chemical biology 20110601

Title: High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides.

Journal: Dalton transactions (Cambridge, England : 2003) 20110227

Title: 8-Hy-droxy-2-methyl-quinolinium tetra-chlorido(quinolin-2-olato-κN,O)stannate(IV) methanol disolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Synthesis and characterization of nano-pore thallium (III) ion-imprinted polymer as a new sorbent for separation and preconcentration of thallium.

Journal: Journal of hazardous materials 20110115

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats.

Journal: PloS one 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: N,N-Dicyclo-hexyl-2-(5,7-dichloro-8-quinol-yloxy)acetamide.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: 5,7-Dichloro-quinolin-8-ol.

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: Synthesis of nano-pore samarium (III)-imprinted polymer for preconcentrative separation of samarium ions from other lanthanide ions via solid phase extraction.

Journal: Analytica chimica acta 20080808

Title: Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.

Journal: The Biochemical journal 20071101

Title: Investigation of the role of chelating ligand in the synthesis of ion-imprinted polymeric resins on the selective enrichment of uranium(VI).

Journal: Analytica chimica acta 20070328

Title: Ion imprinted polymer particles for separation of yttrium from selected lanthanides.

Journal: Journal of separation science 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes.

Journal: Environmental science & technology 20060315

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Solid phase extraction preconcentration of cobalt and nickel with 5,7-dichloroquinone-8-ol embedded styrene-ethylene glycol dimethacrylate polymer particles and determination by flame atomic absorption spectrometry (FAAS).

Journal: Talanta 20050415

Title: Selective recognition of neodymium (III) using ion imprinted polymer particles.

Journal: Journal of molecular recognition : JMR 20050101

Title: Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.

Journal: Breast cancer research : BCR 20050101

Title: A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions.

Journal: The Journal of biological chemistry 20040220

Title: Solid phase extractive preconcentration of thorium onto 5,7-dichloroquinoline-8-ol modified benzophenone.

Journal: Talanta 20021016

Title: Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites.

Journal: Mutation research 19940501

Title: Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action.

Journal: IARC scientific publications 19910101

Title: Renjie X, et al. Solubility modelling, solvent effect and preferential solvation of carbendazim in aqueous co-solvent mixtures of, N,N -dimethylformamide, methanol, ethanol and, n -propanol. J. Chem. Thermodynamics 138 (2019) 288–296.

Title: Chloroxine (Topical). Dec 27, 2018

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SDS
Tags:773-76-2 Molecular Formula|773-76-2 MDL|773-76-2 SMILES|773-76-2 5,7-Dichloroquinolin-8-ol
Catalog No.: AA003M7V
773-76-2,MFCD00006786
773-76-2 | 5,7-Dichloroquinolin-8-ol
Pack Size: 5g
Purity: 98%
in stock
$24.00 $17.00
Pack Size: 25g
Purity: 98%
in stock
$43.00 $30.00
Pack Size: 100g
Purity: 98%
in stock
$162.00 $114.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003M7V
Chemical Name: 5,7-Dichloroquinolin-8-ol
CAS Number: 773-76-2
Molecular Formula: C9H5Cl2NO
Molecular Weight: 214.0481
MDL Number: MFCD00006786
SMILES: Clc1cc(Cl)c2c(c1O)nccc2
Properties
BP: 354.7 °C at 760 mmHg  
Form: Solid  
MP: 178-180 °C(lit.)  
Refractive Index: 1.5500 (estimate)  
Storage: Keep in dry area;Room Temperature;  
Complexity: 191  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 13  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 0  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.5  
Literature fold

Title: Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.

Journal: Journal of medicinal chemistry20130328

Title: Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode.

Journal: Journal of fluorescence20120901

Title: Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

Journal: Journal of medicinal chemistry20110811

Title: Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Journal: Nature chemical biology20110601

Title: High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides.

Journal: Dalton transactions (Cambridge, England : 2003)20110227

Title: 8-Hy-droxy-2-methyl-quinolinium tetra-chlorido(quinolin-2-olato-κN,O)stannate(IV) methanol disolvate.

Journal: Acta crystallographica. Section E, Structure reports online20110201

Title: Synthesis and characterization of nano-pore thallium (III) ion-imprinted polymer as a new sorbent for separation and preconcentration of thallium.

Journal: Journal of hazardous materials20110115

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals20110101

Title: Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats.

Journal: PloS one20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: N,N-Dicyclo-hexyl-2-(5,7-dichloro-8-quinol-yloxy)acetamide.

Journal: Acta crystallographica. Section E, Structure reports online20091101

Title: 5,7-Dichloro-quinolin-8-ol.

Journal: Acta crystallographica. Section E, Structure reports online20090501

Title: Synthesis of nano-pore samarium (III)-imprinted polymer for preconcentrative separation of samarium ions from other lanthanide ions via solid phase extraction.

Journal: Analytica chimica acta20080808

Title: Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.

Journal: The Biochemical journal20071101

Title: Investigation of the role of chelating ligand in the synthesis of ion-imprinted polymeric resins on the selective enrichment of uranium(VI).

Journal: Analytica chimica acta20070328

Title: Ion imprinted polymer particles for separation of yttrium from selected lanthanides.

Journal: Journal of separation science20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes.

Journal: Environmental science & technology20060315

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology20050601

Title: Solid phase extraction preconcentration of cobalt and nickel with 5,7-dichloroquinone-8-ol embedded styrene-ethylene glycol dimethacrylate polymer particles and determination by flame atomic absorption spectrometry (FAAS).

Journal: Talanta20050415

Title: Selective recognition of neodymium (III) using ion imprinted polymer particles.

Journal: Journal of molecular recognition : JMR20050101

Title: Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.

Journal: Breast cancer research : BCR20050101

Title: A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions.

Journal: The Journal of biological chemistry20040220

Title: Solid phase extractive preconcentration of thorium onto 5,7-dichloroquinoline-8-ol modified benzophenone.

Journal: Talanta20021016

Title: Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites.

Journal: Mutation research19940501

Title: Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action.

Journal: IARC scientific publications19910101

Title: Renjie X, et al. Solubility modelling, solvent effect and preferential solvation of carbendazim in aqueous co-solvent mixtures of, N,N -dimethylformamide, methanol, ethanol and, n -propanol. J. Chem. Thermodynamics 138 (2019) 288–296.

Title: Chloroxine (Topical). Dec 27, 2018

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