Name: Name:5-Chloroquinazolin-4(1h)-one
Brand: AABLOCKS
SKU: AA003ML6
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA003ML6

Chemical Name: 5-Chloroquinazolin-4(1h)-one

CAS Number: 60233-66-1

Molecular Formula: C8H5ClN2O

Molecular Weight: 180.5911

MDL Number: MFCD02676498

SMILES: Clc1cccc2c1c(=O)[nH]cn2

NSC Number: 601362

Properties

BP: 353.6°C at 760 mmHg

Form: Solid

Storage: Keep in dry area;2-8℃;

Complexity: 229

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 12

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 1

XLogP3: 1.3

Downstream Synthesis Route

2148-56-3

60100-09-6

60233-66-1

[1]Jiang,Kunming;Li,Zhenjie;Liu,Zhihua;Song,Nali;Tang,Shiyun;Wu,Zhibang;Yang,Chen[RussianJournalofGeneralChemistry,2021,vol.91,#9,p.1757-1766]

[2]Locationinpatent:experimentalpartKulkarni,ShridharS.;Singh,Satyakam;Shah,JankiR.;Low,Woon-Kai;Talele,TanajiT.[EuropeanJournalofMedicinalChemistry,2012,vol.50,p.264-273]

[3]CurrentPatentAssignee:GUIZHOUUNIVERSITY-CN109721554,2019,ALocationinpatent:Paragraph0059;0060

[4]CurrentPatentAssignee:GUIZHOUUNIVERSITY-CN110627731,2019,ALocationinpatent:Paragraph0068;0069

[5]CurrentPatentAssignee:GUIZHOUUNIVERSITY-CN103980209,2016,BLocationinpatent:Paragraph0089;0090;0091

[6]Chiangetal.[HuaxueXuebao/ActaChimicaSinica,1956,vol.22,p.335,336][ScientiaSinica(EnglishEdition),1958,vol.7,p.1035,1036]Bakeretal.[JournalofOrganicChemistry,1952,vol.17,p.149,153]

[7]Zhou,Yuan;Feng,Jiangtao;He,Hongwu;Hou,Leifeng;Jiang,Wen;Xie,Dan;Feng,Lingling;Cai,Meng;Peng,Hao[Biochemistry,2017,vol.56,#49,p.6491-6502]

60233-66-1

2969-81-5

4-(5-chloro-4-oxo-4<i>H</i>-quinazolin-3-yl)-butyricacidethylester

[1]Chao,Qi;Deng,Lynn;Shih,Hsiencheng;Leoni,LorenzoM.;Genini,Davide;Carson,DennisA.;Cottam,HowardB.[JournalofMedicinalChemistry,1999,vol.42,#19,p.3860-3873]

2148-56-3

6313-33-3

60233-66-1

[1]Chao,Qi;Deng,Lynn;Shih,Hsiencheng;Leoni,LorenzoM.;Genini,Davide;Carson,DennisA.;Cottam,HowardB.[JournalofMedicinalChemistry,1999,vol.42,#19,p.3860-3873]

60233-66-1

100-46-9

1258431-82-1

[1]Locationinpatent:experimentalpartShen,Zhen-Lu;He,Xiao-Fei;Hong,Yi-Ming;Hu,Xin-Quan;Mo,Wei-Min;Hu,Bao-Xiang;Sun,Nan[SyntheticCommunications,2011,vol.41,#24,p.3644-3653]

60233-66-1

1449109-08-3

[1]Hu,Baoxiang;Zhang,Xiaochu;Sheng,Lili;Guo,Ming;Shen,Zhenlu;Hu,Xinquan;Sun,Nan;Mo,Weimin[Molecules,2013,vol.18,#5,p.5580-5593]

60233-66-1 | 5-Chloroquinazolin-4(1h)-one