Catalog No.:AA003MP2

51-21-8 | 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

Name: Name:5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
Brand: AABLOCKS
SKU: AA003MP2
Rating: 90 (10 reviews)

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Availability

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Quantity

98%

in stock

$6.00 $4.00

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10g

98%

in stock

$7.00 $5.00

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25g

98%

in stock

$16.00 $11.00

- +

500g

97%

in stock

$311.00 $218.00

Technical Information
Properties
Literature
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Technical Information

Catalog Number:

AA003MP2

Chemical Name:

5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS Number:

51-21-8

Molecular Formula:

C4H3FN2O2

Molecular Weight:

130.0772

MDL Number:

MFCD00006018

SMILES:

Fc1c[nH]c(=O)[nH]c1=O

Properties

BP:

401.4°C at 760 mmHg

Form:

Solid

MP:

282-286 °C (dec.);(lit.);

Solubility:

H2O: 10 mg/mL, clear

Stability:

Air Sensitive

Storage:

Keep in dry area;Room Temperature;

Computed Properties

Complexity:

199

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

XLogP3:

-0.9

Literature

Title: Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print

Title: Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46.

Title: Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948.

Title: McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28.

Title: Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130.

Title: Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88.

Title: Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37.

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