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3471-31-6,MFCD00005638
Catalog No.:AA003MRM

3471-31-6 | 5-Methoxyindole-3-acetic acid

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Purity
Availability
Price(USD)
Quantity
  
250mg
95%
in stock  
$17.00   $12.00
- +
1g
95%
in stock  
$21.00   $15.00
- +
5g
95%
in stock  
$93.00   $65.00
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10g
95%
in stock  
$167.00   $117.00
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25g
95%
in stock  
$376.00   $263.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003MRM
Chemical Name:
5-Methoxyindole-3-acetic acid
CAS Number:
3471-31-6
Molecular Formula:
C11H11NO3
Molecular Weight:
205.2099
MDL Number:
MFCD00005638
SMILES:
COc1ccc2c(c1)c(c[nH]2)CC(=O)O
Properties
Properties
 
BP:
343.88°C (rough estimate)  
Form:
Solid  
MP:
145-148 °C (dec.)(lit.)  
Refractive Index:
1.5130 (estimate)  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
244  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
1.4  

Literature

Title: Alteration of melatonin secretion in patients with type 2 diabetes and proliferative diabetic retinopathy.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Significance of high levels of endogenous melatonin in Mammalian cerebrospinal fluid and in the central nervous system.

Journal: Current neuropharmacology 20100901

Title: Melatonin metabolism in the central nervous system.

Journal: Current neuropharmacology 20100901

Title: Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.

Journal: International journal of molecular sciences 20100101

Title: A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan.

Journal: PloS one 20100101

Title: Effects of naphthalene, beta-naphthoflavone and benzo(a)pyrene on the diurnal and nocturnal indoleamine metabolism and melatonin content in the pineal organ of rainbow trout, Oncorhynchus mykiss.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090402

Title: Melatonin in the skin: synthesis, metabolism and functions.

Journal: Trends in endocrinology and metabolism: TEM 20080101

Title: Binding of ring-substituted indole-3-acetic acids to human serum albumin.

Journal: Bioorganic & medicinal chemistry 20070701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: On-line preconcentration techniques in determination of melatonin and its precursors/metabolites using micellar electrokinetic chromatography.

Journal: Journal of chromatography. A 20060203

Title: Determination of melatonin and its precursors and metabolites using capillary electrophoresis with UV and fluorometric detection.

Journal: Journal of separation science 20051101

Title: Indoleamines and 5-methoxyindoles in trout pineal organ in vivo: daily changes and influence of photoperiod.

Journal: General and comparative endocrinology 20051001

Title: Effect of indole-3-acetic acid derivatives on neuroepithelium in rat embryos.

Journal: The Journal of toxicological sciences 20050801

Title: A foxy intoxication.

Journal: Forensic science international 20050210

Title: Novel stable fluorophore, 6-methoxy-4-quinolone, with strong fluorescence in wide pH range of aqueous media, and its application as a fluorescent labeling reagent.

Journal: Journal of chromatography. A 20041203

Title: Peroxynitrite scavenging activity of indole derivatives: interaction of indoles with peroxynitrite.

Journal: Journal of medicinal food 20040101

Title: Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites.

Journal: Journal of pharmacological sciences 20031201

Title: Photoperiod affects amplitude but not duration of in vitro melatonin production in the ruin lizard (Podarcis sicula).

Journal: Journal of biological rhythms 20030201

Title: Foxy, a designer tryptamine hallucinogen.

Journal: Journal of analytical toxicology 20030101

Title: Total pineal endocrine substitution therapy (TPEST) as a new neuroendocrine palliative treatment of untreatable metastatic solid tumor patients: a phase II study.

Journal: Neuro endocrinology letters 20030101

Title: Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy.

Journal: Bioorganic & medicinal chemistry letters 20020916

Title: Demonstration of antifungal and anti-human immunodeficiency virus reverse transcriptase activities of 6-methoxy-2-benzoxazolinone and antibacterial activity of the pineal indole 5-methoxyindole-3-acetic acid.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

Title: [Morphofunctional changes in the pineal gland during adaptation to hypothermia].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011201

Title: Examination of pineal indoles and 6-methoxy-2-benzoxazolinone for antioxidant and antimicrobial effects.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011101

Title: Effect of light on 5-methoxyindole-3-acetic acid in the rat.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

Journal: The Journal of biological chemistry 19990507

Title: KVEDER S, et al. The metabolism of melatonin (N-acetyl-5-methoxytryptamine) and 5-methoxytryptamine. J Biol Chem. 1961 Dec;236:3214-20.

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