Home Other Building Blocks 60129-59-1
60129-59-1,MFCD00672266
Catalog No.:AA003NCA

60129-59-1 | 7-Deaza-2'-dA

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$63.00   $44.00
- +
250mg
98%
in stock  
$155.00   $109.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NCA
Chemical Name:
7-Deaza-2'-dA
CAS Number:
60129-59-1
Molecular Formula:
C11H14N4O3
Molecular Weight:
250.2539
MDL Number:
MFCD00672266
SMILES:
OC[C@H]1O[C@@H](C[C@@H]1O)n1ccc2c1ncnc2N
Properties
Properties
 
BP:
601°C at 760 mmHg  
Form:
Solid  
MP:
>217°C (dec.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
306  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.4  

Literature

Title: Synthesis and anti-herpetic activity of phosphoramidate ProTides.

Journal: ChemMedChem 20130601

Title: Site-directed spin labeling of DNA reveals mismatch-induced nanometer distance changes between flanking nucleotides.

Journal: The journal of physical chemistry. B 20120412

Title: Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2'-deoxyadenosine:dT base pairing in DNA.

Journal: The journal of physical chemistry. B 20111201

Title: Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.

Journal: Bioorganic & medicinal chemistry 20111001

Title: Site-directed spin-labeling of DNA by the azide-alkyne 'click' reaction: nanometer distance measurements on 7-deaza-2'-deoxyadenosine and 2'-deoxyuridine nitroxide conjugates spatially separated or linked to a 'dA-dT' base pair.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20101227

Title: Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site.

Journal: Chemical communications (Cambridge, England) 20091021

Title: Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7.

Journal: Organic & biomolecular chemistry 20080821

Title: Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells.

Journal: American journal of physiology. Renal physiology 20070201

Title: 4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine: a bis-fluorinated analogue of 2'-deoxytubercidin.

Journal: Acta crystallographica. Section C, Crystal structure communications 20060401

Title: Stabilization of RNA bulges by oligonucleotides containing 2'-naphthylmethyl-2'-deoxytubercidine.

Journal: Nucleosides, nucleotides & nucleic acids 20030101

Title: Renal organic cation and nucleoside transport.

Journal: Biochemical pharmacology 20020715

Title: Fluorescent DNA: the development of 7-deazapurine nucleoside triphosphates applicable for sequencing at the single molecule level.

Journal: Journal of biotechnology 20010413

Title: Design, synthesis, and studies on the structure activity relationships of certain pyrrolo[2,3-d]pyrimidine nucleosides and structurally related analogs as potential antineoplastic and antiviral agents.

Journal: Farmaco (Societa chimica italiana : 1989) 19910101

Title: Nucleic acid related compounds. 51. Synthesis and biological properties of sugar-modified analogues of the nucleoside antibiotics tubercidin, toyocamycin, sangivamycin, and formycin.

Journal: Journal of medicinal chemistry 19870301

Title: Xylotubercidin against herpes simplex virus type 2 in mice.

Journal: Antimicrobial agents and chemotherapy 19861101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:60129-59-1 Molecular Formula|60129-59-1 MDL|60129-59-1 SMILES|60129-59-1 7-Deaza-2'-dA