Home Other Building Blocks 97-18-7
97-18-7,MFCD00055727
Catalog No.:AA003OBN

97-18-7 | Bithionol

Pack Size
Purity
Availability
Price(USD)
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1mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$14.00   $10.00
- +
5g
98%(HPLC)
in stock  
$34.00   $24.00
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25g
≥98%
in stock  
$70.00   $49.00
- +
50g
≥98%
in stock  
$132.00   $92.00
- +
100g
≥98%
in stock  
$246.00   $172.00
- +
500g
>97.0%(GC)(T)
in stock  
$358.00   $251.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003OBN
Chemical Name:
Bithionol
CAS Number:
97-18-7
Molecular Formula:
C12H6Cl4O2S
Molecular Weight:
356.0518
MDL Number:
MFCD00055727
SMILES:
Clc1cc(Sc2cc(Cl)cc(c2O)Cl)c(c(c1)Cl)O
UN Number:
2811
Properties
Properties
 
BP:
444.7°C at 760 mmHg  
Form:
Solid  
MP:
188°C  
Solubility:
DMSO: soluble20mg/mL, clear  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
282  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
5.8  

Literature

Title: A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.

Journal: Antiviral research 20121001

Title: Chemical evolution of autotaxin inhibitors.

Journal: Chemical reviews 20120509

Title: Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2.

Journal: Molecular and biochemical parasitology 20120501

Title: An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.

Journal: Toxicology letters 20120105

Title: The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats.

Journal: International journal of molecular sciences 20120101

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials.

Journal: PLoS neglected tropical diseases 20110901

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: [Cerebral paragonimiasis and Bo Sung Sim's hemispherectomy in Korea in 1950s-1960s].

Journal: Ui sahak 20110630

Title: Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.

Journal: The Journal of investigative dermatology 20110601

Title: Potential drug development candidates for human soil-transmitted helminthiases.

Journal: PLoS neglected tropical diseases 20110601

Title: Determination of Oxyclozanide in Beef and Milk using High-Performance Liquid Chromatography System with UV Detector.

Journal: Laboratory animal research 20110301

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Autotaxin: its role in biology of melanoma cells and as a pharmacological target.

Journal: Enzyme research 20110101

Title: Studies on the anthelmintic property of aminobenzylated mannich bases.

Journal: Journal of young pharmacists : JYP 20110101

Title: SLO-2 is cytoprotective and contributes to mitochondrial potassium transport.

Journal: PloS one 20110101

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD).

Journal: Diseases of aquatic organisms 20100917

Title: Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action.

Journal: Biochemical pharmacology 20100501

Title: A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis.

Journal: Journal of the American Academy of Dermatology 20100401

Title: Endoscopic management of biliary fascioliasis: a case report.

Journal: Journal of medical case reports 20100101

Title: Determination of bithionol, bromophen, nitroxynil, oxyclozanide, and tribromsalan in milk with liquid chromatography coupled with tandem mass spectrometry.

Journal: Journal of AOAC International 20100101

Title: Molecular cloning, expression and characterization of a novel mouse SULT6 cytosolic sulfotransferase.

Journal: Journal of biochemistry 20090901

Title: Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics.

Journal: The Journal of biological chemistry 20090821

Title: Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.

Journal: PLoS neglected tropical diseases 20090701

Title: Diphyllobothriasis associated with eating raw pacific salmon.

Journal: Emerging infectious diseases 20090601

Title: Further development of bithionol therapy as a treatment for amoebic gill disease in Atlantic salmon, Salmo salar L.

Journal: Journal of fish diseases 20090501

Title: Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection.

Journal: The Journal of veterinary medical science 20090501

Title: Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.

Journal: Nature chemical biology 20090401

Title: Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.

Journal: BMC microbiology 20090101

Title: [Phosphatases of cestodes Bothriocephalus scorpii and influence of some anthelmintic preparations on activities of these enzymes].

Journal: Parazitologiia 20090101

Title: The old and new therapeutic approaches to the treatment of giardiasis: where are we?

Journal: Biologics : targets & therapy 20090101

Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

Journal: PloS one 20090101

Title: In Vitro Anthelmintic Activity of Baliospermum montanum Muell. Arg roots.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature.

Journal: PLoS neglected tropical diseases 20071201

Title: An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro.

Journal: Alternatives to laboratory animals : ATLA 20071001

Title: Evaluation of bithionol as a bath treatment for amoebic gill disease caused by Neoparamoeba spp.

Journal: Veterinary parasitology 20070331

Title: Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070307

Title: Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.

Journal: Journal of dermatological science 20070201

Title: Indirect evidence of ectopic pancreatic fascioliasis in a human.

Journal: Journal of gastroenterology and hepatology 20061001

Title: Pharmacological activation and inhibition of Slack (Slo2.2) channels.

Journal: Neuropharmacology 20060901

Title: Fasciola hepatica infection: clinical and computerized tomographic findings of ten patients.

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20060301

Title: Kinetic, inhibition and structural studies on 3-oxoacyl-ACP reductase from Plasmodium falciparum, a key enzyme in fatty acid biosynthesis.

Journal: The Biochemical journal 20060115

Title: Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds.

Journal: Veterinary parasitology 20051125

Title: Infection with Fasciola hepatica.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20051101

Title: Search of chemical scaffolds for novel antituberculosis agents.

Journal: Journal of biomolecular screening 20050401

Title: Acute toxicity to freshwater organisms of antiparasitic drugs for veterinary use.

Journal: Environmental toxicology 20050201

Title: Fasciola hepatica infestation as a very rare cause of extrahepatic cholestasis.

Journal: World journal of gastroenterology 20041015

Title: A native 13-kDa fatty acid binding protein from the liver fluke Fasciola hepatica.

Journal: Biochimica et biophysica acta 20040924

Title: Sonographic findings of hepatic lesions in human fascioliasis.

Journal: Journal of clinical ultrasound : JCU 20030901

Title: Novel openers of Ca2+-dependent large-conductance potassium channels: symmetrical pharmacophore and electrophysiological evaluation of bisphenols.

Journal: Bioorganic & medicinal chemistry letters 20030417

Title: Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules.

Journal: Contact dermatitis 20030301

Title: [Antiparasitic treatments in pregnant women and in children in 2003].

Journal: Medecine tropicale : revue du Corps de sante colonial 20030101

Title: [Fascioliasis: diagnosis, epidemiology and treatment].

Journal: Revista de gastroenterologia de Mexico 20030101

Title: Paragonimiasis in Yongjia County, Zhejiang Province, China: clinical, parasitological and karyotypic studies on Paragonimus westermani.

Journal: The Southeast Asian journal of tropical medicine and public health 20011201

Title: [Fasciola hepatica. study of a series of 37 patients].

Journal: Gastroenterologia y hepatologia 20011001

Title: Hydrogen peroxide induced stress in human keratinocytes and its effect on bithionol toxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010101

Title: Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.

Journal: Annals of tropical medicine and parasitology 19961201

Title: Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugs.

Journal: Antimicrobial agents and chemotherapy 19920901

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