Home Quinolines 6329-61-9
6329-61-9,MFCD00012096
Catalog No.:AA003P6H

6329-61-9 | Decahydroisoquinoline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(GC)
in stock  
$34.00   $24.00
- +
5g
95%
in stock  
$62.00   $44.00
- +
25g
95%
in stock  
$187.00   $131.00
- +
100g
95%
in stock  
$544.00   $381.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003P6H
Chemical Name:
Decahydroisoquinoline
CAS Number:
6329-61-9
Molecular Formula:
C9H17N
Molecular Weight:
139.2380
MDL Number:
MFCD00012096
SMILES:
C1CCC2C(C1)CNCC2
NSC Number:
43479
Properties
Properties
 
BP:
211-214°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.4904(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
111  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Undefined Atom Stereocenter Count:
2  
XLogP3:
2.2  

Downstream Synthesis Route
15115-52-3    6329-61-9   
(trans)-2-(1-phenyl-1H-pyrazol-4-yl)-decahydroisoquinoline 

[1]OrganicProcessResearchandDevelopment,2019,vol.23,p.1725-1739

Literature

Title: Protic ionic liquids based on decahydroisoquinoline: lost superfragility and ionicity-fragility correlation.

Journal: The journal of physical chemistry. B 20120112

Title: Physiology and pathology of calcium signaling in the brain.

Journal: Frontiers in pharmacology 20120101

Title: Essential structure of opioid κ receptor agonist nalfurafine for binding to κ receptor 1: synthesis of decahydroisoquinoline derivatives and their pharmacologies.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Sulfinylated azadecalins act as functional mimics of a pollen germination stimulant in Arabidopsis pistils.

Journal: The Plant journal : for cell and molecular biology 20111201

Title: Remodelling of the natural product fumagillol employing a reaction discovery approach.

Journal: Nature chemistry 20111201

Title: Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir.

Journal: PLoS computational biology 20110401

Title: Amygdalar glutamatergic neuronal systems play a key role on the hibernating state of hamsters.

Journal: BMC neuroscience 20110101

Title: Molecular Basis for Drug Resistance in HIV-1 Protease.

Journal: Viruses 20101101

Title: Straightforward assembly of the octahydroisoquinoline core of morphinan alkaloids.

Journal: Organic letters 20100521

Title: Diastereoselective synthesis of a highly functionalized angularly substituted cis-perhydroisoquinoline-3,6-dione via organoiron.

Journal: The Journal of organic chemistry 20100305

Title: Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20100301

Title: Abundant lattice inclusion phenomenon with sterically hindered and inherently shape-selective tetraarylpyrenes.

Journal: The Journal of organic chemistry 20091120

Title: Drug-resistant molecular mechanism of CRF01_AE HIV-1 protease due to V82F mutation.

Journal: Journal of computer-aided molecular design 20090501

Title: 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.

Journal: Bioorganic & medicinal chemistry letters 20080215

Title: 2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20071015

Title: Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding.

Journal: Organic & biomolecular chemistry 20060321

Title: Dielectric and shear mechanical alpha and beta relaxations in seven glass-forming liquids.

Journal: The Journal of chemical physics 20051215

Title: Two secondary modes in decahydroisoquinoline: which one is the true Johari Goldstein process?

Journal: The Journal of chemical physics 20050615

Title: Locomotor activity detects subunit-selective effects of agonists and decahydroisoquinoline antagonists at AMPA/kainic acid ionotropic glutamate receptors in adult rats.

Journal: Psychopharmacology 20050401

Title: Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines.

Journal: BMC pharmacology 20050101

Title: Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro.

Journal: Neuropharmacology 20040501

Title: Rhodium-catalyzed anti-Markovnikov hydroamination of vinylarenes.

Journal: Journal of the American Chemical Society 20030514

Title: [Synthetic study of biologically important nitrogen containing natural products: development of new methodology and design of leading compounds for new pharmaceuticals].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030401

Title: CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020101

Title: Ring closing metathesis mediated synthesis of 4a-aryloxodecahydroisoquinolines, intermediates in the preparation of novel opiates.

Journal: Organic letters 20011101

Title: Inhibitors of AMPA and kainate receptors.

Journal: Current medicinal chemistry 20010901

Title: Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse.

Journal: Neuropharmacology 20010101

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