Home Amines 2438-32-6
2438-32-6,MFCD00079046
Catalog No.:AA003P77

2438-32-6 | DeXchlorpheniramine Maleate, USP

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25mg
99%(HPLC)powder
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100mg
99%(HPLC)powder
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500mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003P77
Chemical Name:
DeXchlorpheniramine Maleate, USP
CAS Number:
2438-32-6
Molecular Formula:
C20H23ClN2O4
Molecular Weight:
390.8606
MDL Number:
MFCD00079046
SMILES:
CN(CC[C@H](c1ccccn1)c1ccc(cc1)Cl)C.OC(=O)/C=C\C(=O)O
Properties
Properties
 
BP:
379°C at 760 mmHg  
Form:
Solid  
MP:
97-113°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
368  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  

Literature

Title: An approach to formulating an oral floating drug delivery system for dexchlorpheniramine maleate using factorial design.

Journal: Die Pharmazie 20120701

Title: [Anaesthetic treatment in the removal of a cardiac hydatid cyst].

Journal: Revista espanola de anestesiologia y reanimacion 20120101

Title: Focal rituximab-induced edematous reaction at primary cutaneous follicle center lymphoma lesions: case report and literature review.

Journal: Dermatology (Basel, Switzerland) 20110101

Title: Urticaria due to aloe vera: a new sensitizer?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20101101

Title: Management of allergic and non-allergic rhinitis: a primary care summary of the BSACI guideline.

Journal: Primary care respiratory journal : journal of the General Practice Airways Group 20100901

Title: Determination of chlorpheniramine in human plasma by HPLC-ESI-MS/MS: application to a dexchlorpheniramine comparative bioavailability study.

Journal: Biomedical chromatography : BMC 20100701

Title: Memory in humans is unaffected by central H1-antagonism, while objectively and subjectively measured sedation is increased.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100401

Title: [Systemic mastocytosis and perioperative management: a report of 2 cases].

Journal: Revista espanola de anestesiologia y reanimacion 20100301

Title: [Protocol for inducing infliximab tolerance in a patient with psoriatic spondylarthritis].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

Title: Histamine H1 receptor blockade predominantly impairs sensory processes in human sensorimotor performance.

Journal: British journal of pharmacology 20090501

Title: [Efficacy of premedication with intravenous corticosteroids and antihistaminics in preventing infusion reactions to infliximab].

Journal: Gastroenterologia y hepatologia 20081201

Title: Histamine H1-receptor blockade in humans affects psychomotor performance but not memory.

Journal: Journal of psychopharmacology (Oxford, England) 20080801

Title: Anaphylaxis induced by Anisakis.

Journal: Allergologia et immunopathologia 20080101

Title: Anaphylaxis to oral iron salts. desensitization protocol for tolerance induction.

Journal: Journal of investigational allergology & clinical immunology 20080101

Title: Anaphylactic reaction to ranitidine and dexchlorpheniramine.

Journal: European journal of dermatology : EJD 20070101

Title: [Description of an outbreak of lepidopterism (dermatitis associated with contact with moths) among sailors in Salvador, State of Bahia].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance.

Journal: British journal of clinical pharmacology 20060101

Title: Severe anaphylactic reaction after intracameral antibiotic administration during cataract surgery.

Journal: Journal of cataract and refractive surgery 20050301

Title: An unusual adverse drug reaction?

Journal: Allergologia et immunopathologia 20050101

Title: Derivative ultraviolet spectrophotometric determination of dexchlorpheniramine maleate in tablets in presence of coloring agents.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

Title: A case of probable codeine poisoning in a young infant after the use of a proprietary cough and cold medicine.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20040801

Title: A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040201

Title: Allergy to dexchlorpheniramine. Study of a case.

Journal: Allergologia et immunopathologia 20040101

Title: [Herpes gestationis].

Journal: Acta medica portuguesa 20040101

Title: Aseptic meningitis associated with intravenous administration of dexchlorpheniramine.

Journal: Annales de medecine interne 20030501

Title: Self-assembly of drug-polymer complexes: a spontaneous nanoencapsulation process monitored by atomic force microscopy.

Journal: Journal of pharmaceutical sciences 20030101

Title: Two cases of cross-sensitivity in subjects allergic to paraphenylenediamine following ingestion of Polaronil.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Anaphylactoid reaction to carboplatin: successful 'desensitization'.

Journal: Allergologia et immunopathologia 20030101

Title: The involvement of nervous and some inflammatory response mechanisms in the acute snuff-induced gingival hyperaemia in humans.

Journal: Journal of clinical periodontology 20020901

Title: Sequential atomic force microscopy imaging of a spontaneous nanoencapsulation process.

Journal: International journal of pharmaceutics 20020821

Title: [The potential P300 in the evaluation of the side effects of dexchlorpheniramine].

Journal: Revista de neurologia 20020801

Title: Development of a validated capillary electrophoresis method for enantiomeric purity testing of dexchlorpheniramine maleate.

Journal: Journal of chromatography. A 20020607

Title: The H1-receptor antagonist dextro-chlorpheniramine impairs selective auditory attention in the absence of subjective awareness of this impairment.

Journal: Journal of clinical psychopharmacology 20011201

Title: Stereospecific versus nonstereospecific assessments for the bioequivalence of two formulations of racemic chlorpheniramine.

Journal: Chirality 20000801

Title: Binding of chlorpheniramine enantiomers to human plasma proteins.

Journal: Chirality 19990101

Title: [Dexchlorpheniramine-induced acute hepatitis: a case with positive rechallenge].

Journal: Gastroenterologie clinique et biologique 19981001

Title: Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes.

Journal: The Journal of pharmacy and pharmacology 19970301

Title: Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults.

Journal: European journal of clinical pharmacology 19820101

Title: The I antigen as an immune complex receptor in a case of haemolytic anaemia induced by an antihistaminic agent.

Journal: British journal of haematology 19810901

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Tags:2438-32-6 Molecular Formula|2438-32-6 MDL|2438-32-6 SMILES|2438-32-6 DeXchlorpheniramine Maleate, USP