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20263-07-4,MFCD12546565
Catalog No.:AA003PPW

20263-07-4 | DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID

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100mg
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$186.00   $130.00
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250mg
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500mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003PPW
Chemical Name:
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
CAS Number:
20263-07-4
Molecular Formula:
C4H10NO5P
Molecular Weight:
183.0997
MDL Number:
MFCD12546565
SMILES:
C(CP(=O)(O)O)C(C(=O)O)N
Properties
Properties
 
Form:
Solid  
MP:
225 °C  

Computed Properties
 
Complexity:
187  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-5.5  

Literature

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Journal: Investigative ophthalmology & visual science 20120817

Title: A retinal ganglion cell that can signal irradiance continuously for 10 hours.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815

Title: Pancreatic insulin and exocrine secretion are under the modulatory control of distinct subpopulations of vagal motoneurones in the rat.

Journal: The Journal of physiology 20120801

Title: Behavioral responses to glutamate receptor agonists and antagonists implicate the involvement of brain-expressed mGluR4 and mGluR1 in taste transduction for umami in mice.

Journal: Physiology & behavior 20120201

Title: Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.

Journal: Scientific reports 20120101

Title: Topological analysis of small leucine-rich repeat proteoglycan nyctalopin.

Journal: PloS one 20120101

Title: Novel expression patterns of metabotropic glutamate receptor 6 in the zebrafish nervous system.

Journal: PloS one 20120101

Title: Rod-driven OFF pathway responses in the distal retina: dark-adapted flicker electroretinogram in mouse.

Journal: PloS one 20120101

Title: High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons.

Journal: Hippocampus 20111201

Title: Retinal pathway origins of the pattern electroretinogram (PERG).

Journal: Investigative ophthalmology & visual science 20111101

Title: Glutamatergic modulation of separation distress: profound emotional effects of excitatory amino acids in chicks.

Journal: Neuroscience and biobehavioral reviews 20111001

Title: Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.

Journal: Investigative ophthalmology & visual science 20110929

Title: Rapid plasticity of visual responses in the adult lateral geniculate nucleus.

Journal: Neuron 20110908

Title: Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.

Journal: Behavioural pharmacology 20110901

Title: Mechanism of voriconazole-induced transient visual disturbance: reversible dysfunction of retinal ON-bipolar cells in monkeys.

Journal: Investigative ophthalmology & visual science 20110707

Title: Post-receptoral contributions to the rat scotopic electroretinogram a-wave.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20110601

Title: Amacrine-to-amacrine cell inhibition: Spatiotemporal properties of GABA and glycine pathways.

Journal: Visual neuroscience 20110501

Title: Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system.

Journal: Addiction biology 20110101

Title: Transcorneal electrical stimulation improves visual function in eyes with branch retinal artery occlusion.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Congenital nystagmus and negative electroretinography.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Harmonic analysis of the cone flicker ERG of rabbit.

Journal: Experimental eye research 20101201

Title: Nitric oxide amplifies the rat electroretinogram.

Journal: Experimental eye research 20101101

Title: S100A1: a multifaceted therapeutic target in cardiovascular disease.

Journal: Journal of cardiovascular translational research 20101001

Title: Distinct retinal deficits in a zebrafish pyruvate dehydrogenase-deficient mutant.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100908

Title: Pharmacological dissection of multifocal electroretinograms of rabbits with Pro347Leu rhodopsin mutation.

Journal: Japanese journal of ophthalmology 20100901

Title: Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease.

Journal: British journal of pharmacology 20100801

Title: Modulation of taurine release in ischemia by glutamate receptors in mouse brain stem slices.

Journal: Amino acids 20100301

Title: Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression.

Journal: BMC genomics 20100101

Title: Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats.

Journal: Journal of pharmacological sciences 20100101

Title: Calcium sets the physiological value of the dominant time constant of saturated mouse rod photoresponse recovery.

Journal: PloS one 20100101

Title: Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus.

Journal: Frontiers in synaptic neuroscience 20100101

Title: Crossover inhibition in the retina: circuitry that compensates for nonlinear rectifying synaptic transmission.

Journal: Journal of computational neuroscience 20091201

Title: Stimulus-evoked intrinsic optical signals in the retina: pharmacologic dissection reveals outer retinal origins.

Journal: Investigative ophthalmology & visual science 20091001

Title: High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina.

Journal: Nature neuroscience 20090901

Title: Mechanisms that limit the light stimulus frequency following through the DL-2-amino-4-phosphonobutyric acid sensitive and insensitive rod Off-pathways.

Journal: Neuroscience 20090804

Title: The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.

Journal: Brain research 20090728

Title: Translocation of a 'winner' climbing fiber to the Purkinje cell dendrite and subsequent elimination of 'losers' from the soma in developing cerebellum.

Journal: Neuron 20090716

Title: Retinal pathway origins of the pattern ERG of the mouse.

Journal: Experimental eye research 20090615

Title: Pharmacological analysis of feeding in a caterpillar: different transduction pathways for umami and saccharin?

Journal: Die Naturwissenschaften 20090501

Title: Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment.

Journal: Journal of neurochemistry 20090501

Title: Partial compensation for N-type Ca(2+) channel loss by P/Q-type Ca(2+) channels underlines the differential release properties supported by these channels at cerebrocortical nerve terminals.

Journal: The European journal of neuroscience 20090301

Title: [Development of a functional cell-based HTS assay for the identification mGluR4 modulators].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090301

Title: Coagonist release modulates NMDA receptor subtype contributions at synaptic inputs to retinal ganglion cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090204

Title: Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain.

Journal: Neuroscience 20090123

Title: At immature mossy fibers-CA3 connections, activation of presynaptic GABA(B) receptors by endogenously released GABA contributes to synapses silencing.

Journal: Frontiers in cellular neuroscience 20090101

Title: Light-induced fos expression in intrinsically photosensitive retinal ganglion cells in melanopsin knockout (opn4) mice.

Journal: PloS one 20090101

Title: The characteristics of multifocal electroretinogram in isolated perfused porcine eye: cellular contributions to the in vitro porcine mfERG.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20081101

Title: Modeling convergent ON and OFF pathways in the early visual system.

Journal: Biological cybernetics 20081101

Title: Amacrine-to-amacrine cell inhibition in the rabbit retina.

Journal: Journal of neurophysiology 20081001

Title: Increases in intracellular calcium triggered by channelrhodopsin-2 potentiate the response of metabotropic glutamate receptor mGluR7.

Journal: The Journal of biological chemistry 20080905

Title: Behavioral comparison of sucrose and l-2-amino-4-phosphonobutyrate (L-AP4) tastes in rats: does L-AP4 have a sweet taste?

Journal: Neuroscience 20080813

Title: P2Y receptor mediated inhibitory modulation of noradrenaline release in response to electrical field stimulation and ischemic conditions in superfused rat hippocampus slices.

Journal: Journal of neurochemistry 20080701

Title: Two distinct processes are evident in rat cone flicker ERG responses at low and high temporal frequencies.

Journal: Experimental eye research 20080701

Title: Porcine global flash multifocal electroretinogram: possible mechanisms for the glaucomatous changes in contrast response function.

Journal: Vision research 20080701

Title: Postreceptoral contributions to the light-adapted ERG of mice lacking b-waves.

Journal: Experimental eye research 20080601

Title: Pharmacologically defined components of the normal porcine multifocal ERG.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20080501

Title: Multifocal electroretinogram in rhodopsin P347L transgenic pigs.

Journal: Investigative ophthalmology & visual science 20080501

Title: Metabotropic glutamate receptors regulate differentiation of embryonic stem cells into GABAergic neurons.

Journal: Cell death and differentiation 20080401

Title: Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated.

Journal: Neuropharmacology 20080401

Title: Additive neuroprotection by metabotropic glutamate receptor subtype-selective ligands in a rat Parkinson's model.

Journal: Neuroreport 20080305

Title: Comparison of focal macular cone ERGs in complete-type congenital stationary night blindness and APB-treated monkeys.

Journal: Vision research 20080101

Title: Localization of metabotropic glutamate receptors in the outer plexiform layer of the goldfish retina.

Journal: Cell and tissue research 20071201

Title: Inhibitory feedback shapes bipolar cell responses in the rabbit retina.

Journal: Journal of neurophysiology 20071201

Title: Modulation of a spinal locomotor network by metabotropic glutamate receptors.

Journal: The European journal of neuroscience 20071001

Title: Infection control by antibody disruption of bacterial quorum sensing signaling.

Journal: Chemistry & biology 20071001

Title: L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.

Journal: Journal of medicinal chemistry 20070920

Title: Synthesis and biological evaluation of 1-amino-2-phosphonomethylcyclopropanecarboxylic acids, new group III metabotropic glutamate receptor agonists.

Journal: Journal of medicinal chemistry 20070726

Title: Differential expression of cerebellar metabotropic glutamate receptors mGLUR2/3 and mGLUR4a after the administration of a convulsant drug and the adenosine analogue cyclopentyladenosine.

Journal: Neurochemical research 20070701

Title: D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.

Journal: Canadian journal of physiology and pharmacology 20070501

Title: Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo.

Journal: Neuroscience 20070425

Title: Distribution of group-III metabotropic glutamate receptors in the retina.

Journal: The Journal of comparative neurology 20070420

Title: Experience-dependent binocular competition in the visual cortex begins at eye opening.

Journal: Nature neuroscience 20070301

Title: Retinal ganglion cells can rapidly change polarity from Off to On.

Journal: PLoS biology 20070301

Title: Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Evidence that L-AP5 and D,L-AP4 can preferentially block cone signals in the rat retina.

Journal: Visual neuroscience 20070101

Title: Functional polarity of dendrites and axons of primate A1 amacrine cells.

Journal: Visual neuroscience 20070101

Title: Test of the paired-flash electroretinographic method in mice lacking b-waves.

Journal: Visual neuroscience 20070101

Title: Response properties of a unique subtype of wide-field amacrine cell in the rabbit retina.

Journal: Visual neuroscience 20070101

Title: Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.

Journal: Journal of neurophysiology 20061001

Title: Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors.

Journal: Neuropharmacology 20060901

Title: Diastereoselective synthesis of 2-amino-4-phosphonobutanoic acids by electrophilic substitution and tin-Peterson olefination of bis-lactim ethers derived from cyclo-[L-AP4-D-Val].

Journal: The Journal of organic chemistry 20060901

Title: In vivo electrical stimulation of rabbit retina: effect of stimulus duration and electrical field orientation.

Journal: Experimental eye research 20060801

Title: The cannabinoid CB1 receptor antagonist SR 141716A induces penile erection by increasing extra-cellular glutamic acid in the paraventricular nucleus of male rats.

Journal: Behavioural brain research 20060515

Title: Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060419

Title: Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus.

Journal: European journal of pharmacology 20060327

Title: Contribution of retinal neurons to d-wave of primate photopic electroretinograms.

Journal: Vision research 20060301

Title: GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111

Title: Unique functional properties of the APB sensitive and insensitive rod pathways signaling light decrements in mouse retinal ganglion cells.

Journal: Visual neuroscience 20060101

Title: Electrophysiological effects of three groups of glutamate metabotropic receptors in rat piriform cortex.

Journal: Cellular and molecular neurobiology 20060101

Title: Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus.

Journal: Critical reviews in neurobiology 20060101

Title: Roscovitine triggers excitotoxicity in cultured granule neurons by enhancing glutamate release.

Journal: Molecular pharmacology 20051101

Title: Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease.

Journal: The European journal of neuroscience 20051001

Title: Spontaneous oscillatory activity of starburst amacrine cells in the mouse retina.

Journal: Journal of neurophysiology 20050901

Title: Distinct mechanisms of presynaptic inhibition at GABAergic synapses of the rat substantia nigra pars compacta.

Journal: Journal of neurophysiology 20050901

Title: Cardiovascular response to a group III mGluR agonist in NTS requires NMDA receptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050701

Title: Light signaling in scotopic conditions in the rabbit, mouse and rat retina: a physiological and anatomical study.

Journal: Journal of neurophysiology 20050601

Title: Group III metabotropic glutamate-receptor-mediated modulation of excitatory transmission in rodent substantia nigra pars compacta dopamine neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20050601

Title: Third-order neuronal responses contribute to shaping the negative electroretinogram in sodium iodate-treated rats.

Journal: Current eye research 20050601

Title: Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050501

Title: Activation of metabotropic glutamate receptors inhibits high-voltage-gated calcium channel currents of chicken nucleus magnocellularis neurons.

Journal: Journal of neurophysiology 20050301

Title: mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivity.

Journal: Neuropharmacology 20050301

Title: Enhancement of glutamate uptake mediates the neuroprotection exerted by activating group II or III metabotropic glutamate receptors on astrocytes.

Journal: Journal of neurochemistry 20050201

Title: Ultraviolet- and short-wavelength cone contributions alter the early components of the ERG of young zebrafish.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050201

Title: (2S,1'S,2'R,3'R)-2(2'-Carboxy-3'-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors.

Journal: Bioorganic & medicinal chemistry letters 20050117

Title: 2,3-Ethylene- and 2,3-trimethylene-bridged analogues of the group III metabotropic glutamate receptor ligand 2-amino-4-phosphonobutanoic acid.

Journal: Bioorganic & medicinal chemistry letters 20050103

Title: Retinal bipolar cell input mechanisms in giant danio. I. Electroretinographic analysis.

Journal: Journal of neurophysiology 20050101

Title: Retinal bipolar cell input mechanisms in giant danio. II. Patch-clamp analysis of on bipolar cells.

Journal: Journal of neurophysiology 20050101

Title: Primate Retinal Signaling Pathways: Suppressing ON-Pathway Activity in Monkey With Glutamate Analogues Mimics Human CSNB1-NYX Genetic Night Blindness.

Journal: Journal of neurophysiology 20050101

Title: Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: Immunoreactivity for the group III receptor subtype mGluR4a in the visual layers of the rat superior colliculus.

Journal: Neuroscience 20050101

Title: Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus.

Journal: Neuropharmacology 20050101

Title: Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare.

Journal: Neuropharmacology 20050101

Title: Modulation of retino-collicular transmission by Group III metabotropic glutamate receptors at different ages during development.

Journal: Neuropharmacology 20050101

Title: Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats.

Journal: Neuropharmacology 20050101

Title: Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level.

Journal: Neuropharmacology 20050101

Title: Pharmacological studies of the mouse cone electroretinogram.

Journal: Visual neuroscience 20050101

Title: Convergence and segregation of the multiple rod pathways in mammalian retina.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041208

Title: Rodent lymphocytes express functionally active glutamate receptors.

Journal: Biochemical and biophysical research communications 20041105

Title: Molecular basis for the differential agonist affinities of group III metabotropic glutamate receptors.

Journal: Molecular pharmacology 20041001

Title: Regulation of transmitter release by high-affinity group III mGluRs in the supraoptic nucleus of the rat hypothalamus.

Journal: Neuropharmacology 20040901

Title: Changes in metabotropic glutamate receptor 4 expression and the effects of L-2-amino-4-phosphonobutyrate in a rodent model of diffuse brain injury.

Journal: Chinese journal of traumatology = Zhonghua chuang shang za zhi 20040801

Title: Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040615

Title: Extracellular excitatory amino acids increase in the paraventricular nucleus of male rats during sexual activity: main role of N-methyl-d-aspartic acid receptors in erectile function.

Journal: The European journal of neuroscience 20040501

Title: Distinct properties of presynaptic group II and III metabotropic glutamate receptor-mediated inhibition of perforant pathway-CA1 EPSCs.

Journal: The European journal of neuroscience 20040501

Title: Glutamate taste: Discrimination between the tastes of glutamate agonists and monosodium glutamate in rats.

Journal: Chemical senses 20040501

Title: Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.

Journal: European journal of pharmacology 20040319

Title: Luminance dependence of neural components that underlies the primate photopic electroretinogram.

Journal: Investigative ophthalmology & visual science 20040301

Title: Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.

Journal: Neuron 20040205

Title: Rod and cone signaling transmission in the retina of zebrafish: an erg study.

Journal: The International journal of neuroscience 20040201

Title: Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats.

Journal: Neuropharmacology 20040201

Title: Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat.

Journal: British journal of pharmacology 20040101

Title: Development of On and Off retinal pathways and retinogeniculate projections.

Journal: Progress in retinal and eye research 20040101

Title: Neurotransmitter actions on transient amacrine and ganglion cells of the turtle retina.

Journal: Visual neuroscience 20040101

Title: Functionally intact glutamate-mediated signaling in bipolar cells of the TRKB knockout mouse retina.

Journal: Visual neuroscience 20040101

Title: Normal photoresponses and altered b-wave responses to APB in the mdx(Cv3) mouse isolated retina ERG supports role for dystrophin in synaptic transmission.

Journal: Visual neuroscience 20040101

Title: Long-term treatment of the developing retina with the metabotropic glutamate agonist APB induces long-term changes in the stratification of retinal ganglion cell dendrites.

Journal: Developmental neuroscience 20040101

Title: Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens.

Journal: Journal of neurochemistry 20031201

Title: Sildenafil, N-desmethyl-sildenafil and Zaprinast enhance photoreceptor response in the isolated rat retina.

Journal: Neurochemistry international 20031101

Title: Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20031101

Title: Utilisation of structurally diverse organophosphonates by Streptomycetes.

Journal: Applied microbiology and biotechnology 20031001

Title: Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030806

Title: Functional damage to inner and outer retinal cells in experimental glaucoma.

Journal: Investigative ophthalmology & visual science 20030801

Title: Endogenous zinc as a retinal neuromodulator: evidence from the skate (Raja erinacea).

Journal: Neuroscience letters 20030717

Title: Regional variations in local contributions to the primate photopic flash ERG: revealed using the slow-sequence mfERG.

Journal: Investigative ophthalmology & visual science 20030701

Title: Co-expression of metabotropic glutamate receptor 7 and N-type Ca(2+) channels in single cerebrocortical nerve terminals of adult rats.

Journal: The Journal of biological chemistry 20030627

Title: Stimulation of sodium pump restores membrane potential to neurons excited by glutamate in zebrafish distal retina.

Journal: The Journal of physiology 20030615

Title: Actions of LY341495 on metabotropic glutamate receptor-mediated responses in the neonatal rat spinal cord.

Journal: British journal of pharmacology 20030501

Title: Different circuits for ON and OFF retinal ganglion cells cause different contrast sensitivities.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401

Title: Down-regulation of mGluR8 in pilocarpine epileptic rats.

Journal: Synapse (New York, N.Y.) 20030315

Title: Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315

Title: Participation of the GABAergic system in the action of 2-amino-4-phosphonobutyrate on the OFF responses of frog retinal ganglion cells.

Journal: Vision research 20030301

Title: Metabotropic glutamate and muscarinic cholinergic receptor-mediated preferential inhibition of N-methyl-D-aspartate component of transmissions in rat ventral tegmental area.

Journal: Neuroscience 20030101

Title: Increased c-Fos expression in the centromedial nucleus of the thalamus in metabotropic glutamate 8 receptor knockout mice following the elevated plus maze test.

Journal: Neuroscience 20030101

Title: Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retina.

Journal: Visual neuroscience 20030101

Title: Pharmacological analysis of the rat cone electroretinogram.

Journal: Visual neuroscience 20030101

Title: Activation of group III metabotropic glutamate receptors presynaptically reduces both GABAergic and glutamatergic transmission in the rat globus pallidus.

Journal: Neuroscience 20030101

Title: Subtype-specific expression of group III metabotropic glutamate receptors and Ca2+ channels in single nerve terminals.

Journal: The Journal of biological chemistry 20021206

Title: No ON-OFF maps in supragranular layers of ferret visual cortex.

Journal: Journal of neurophysiology 20021001

Title: Metabotropic glutamate receptor expression in the rat superior cervical ganglion.

Journal: Neuroscience letters 20020927

Title: Multisubstrate analogue inhibitors of glucosamine-6-phosphate synthase from Candida albicans.

Journal: Bioorganic & medicinal chemistry letters 20020916

Title: Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei.

Journal: The Journal of physiology 20020915

Title: Differential coupling of N- and P/Q-type calcium channels to glutamate exocytosis in the rat cerebral cortex.

Journal: Neuroscience letters 20020913

Title: Activation of brainstem metabotropic glutamate receptors inhibits spinal nociception in adult rats.

Journal: Pharmacology, biochemistry, and behavior 20020901

Title: Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.

Journal: Pharmacology, biochemistry, and behavior 20020901

Title: Effects of APB, PDA, and TTX on ERG responses recorded using both multifocal and conventional methods in monkey. Effects of APB, PDA, and TTX on monkey ERG responses.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20020901

Title: Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques. Macaque photopic sinusoidal flicker ERG.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20020901

Title: Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.

Journal: Journal of medicinal chemistry 20020718

Title: Post-photoreceptoral activity dominates primate photopic 32-Hz ERG for sine-, square-, and pulsed stimuli.

Journal: Investigative ophthalmology & visual science 20020701

Title: Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701

Title: Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways.

Journal: Journal of neurochemistry 20020701

Title: PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7.

Journal: The EMBO journal 20020617

Title: Group III mGluR-mediated depression of sensory synaptic transmission.

Journal: Brain research 20020524

Title: Retinal origins of the primate multifocal ERG: implications for the human response.

Journal: Investigative ophthalmology & visual science 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia.

Journal: European journal of pharmacology 20020222

Title: Synaptic transmission in nucleus tractus solitarius is depressed by Group II and III but not Group I presynaptic metabotropic glutamate receptors in rats.

Journal: The Journal of physiology 20020201

Title: Role of group II and group III metabotropic glutamate receptors in spinal cord injury.

Journal: Experimental neurology 20020101

Title: Evidence that a-wave latency of the electroretinogram is determined solely by photoreceptors.

Journal: Japanese journal of ophthalmology 20020101

Title: Activation of Group III mGluRs increases the activity of neurons in area 17 of the cat.

Journal: Visual neuroscience 20020101

Title: APB differentially affects the cone contributions to the zebrafish ERG.

Journal: Visual neuroscience 20020101

Title: Multiplied functions unify shapes of ganglion-cell receptive fields in retina of turtle.

Journal: Journal of vision 20020101

Title: Control of Ca(2+) influx by cannabinoid and metabotropic glutamate receptors in rat cerebellar cortex requires K(+) channels.

Journal: The Journal of physiology 20011215

Title: Modulation of primary afferent-mediated neurotransmission and Fos expression by glutamate uptake inhibition in rat spinal neurones in vitro.

Journal: Neuropharmacology 20011001

Title: Effect of glutamate analogues on red-green opponent interaction in monkey electroretinograms.

Journal: Experimental eye research 20010901

Title: Role of metabotropic glutamate receptors in vasopressin and oxytocin release.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010801

Title: Metabotropic glutamate receptor subtypes modulating neurotransmission at parallel fibre-Purkinje cell synapses in rat cerebellum.

Journal: Neuropharmacology 20010701

Title: Unique functional properties of on and off pathways in the developing mammalian retina.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615

Title: The group I metabotropic glutamate receptor antagonist S-4-CPG modulates the locomotor response produced by the activation of D1-like, but not D2-like, dopamine receptors in the rat nucleus accumbens.

Journal: The European journal of neuroscience 20010601

Title: Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.

Journal: The Biochemical journal 20010515

Title: Control of glutamate clearance and synaptic efficacy by glial coverage of neurons.

Journal: Science (New York, N.Y.) 20010504

Title: Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.

Journal: Journal of neurophysiology 20010501

Title: On-bipolar cells and depolarising third-order neurons as the origin of the ERG-b-wave in the RCS rat.

Journal: Vision research 20010401

Title: Behavioral taste similarities and differences among monosodium L-glutamate and glutamate receptor agonists in C57BL mice.

Journal: Journal of nutritional science and vitaminology 20010401

Title: Investigations of photoreceptor synaptic transmission and light adaptation in the zebrafish visual mutant nrc.

Journal: Investigative ophthalmology & visual science 20010301

Title: beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor.

Journal: Journal of neurophysiology 20010301

Title: Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts.

Journal: Biochemical and biophysical research communications 20010223

Title: Immunoreactivity for the group III metabotropic glutamate receptor subtype mGluR4a in the superficial laminae of the rat spinal dorsal horn.

Journal: The Journal of comparative neurology 20010219

Title: Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices.

Journal: Neurochemical research 20010201

Title: Intensity-dependent, rapid activation of presynaptic metabotropic glutamate receptors at a central synapse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115

Title: Primate photopic sine-wave flicker ERG: vector modeling analysis of component origins using glutamate analogs.

Journal: Investigative ophthalmology & visual science 20010101

Title: cAMP-dependent presynaptic regulation of spontaneous glycinergic IPSCs in mechanically dissociated rat spinal cord neurons.

Journal: Journal of neurophysiology 20010101

Title: Intraretinal analysis of the a-wave of the electroretinogram (ERG) in dark-adapted intact cat retina.

Journal: Visual neuroscience 20010101

Title: Characterization of the rod photoresponse isolated from the dark-adapted primate ERG.

Journal: Visual neuroscience 20010101

Title: Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala.

Journal: Journal of neurophysiology 20000801

Title: Effect of the umami peptides on the ligand binding and function of rat mGlu4a receptor might implicate this receptor in the monosodium glutamate taste transduction.

Journal: British journal of pharmacology 19991101

Title: Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis.

Journal: British journal of pharmacology 19990601

Title: Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina.

Journal: Neuropharmacology 19970101

Title: Cloning and characterization of a metabotropic glutamate receptor, mGluR4b.

Journal: Neuropharmacology 19970101

Title: Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.

Journal: British journal of pharmacology 19960101

Title: [3H]-L-2-amino-4-phosphonobutyrate labels a metabotropic glutamate receptor, mGluR4a.

Journal: British journal of pharmacology 19951201

Title: Induction or protection of limbic seizures in mice by mGluR subtype selective agonists.

Journal: Neuropharmacology 19950801

Title: Pharmacological evidence for an involvement of group II and group III mGluRs in the presynaptic regulation of excitatory synaptic responses in the CA1 region of rat hippocampal slices.

Journal: Neuropharmacology 19950801

Title: Efficient Fmoc/solid-phase synthesis of Abu(P)-containing peptides using Fmoc-Abu(PO3Me2)-OH.

Journal: International journal of peptide and protein research 19940901

Title: A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.

Journal: Brain research 19930813

Title: L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase.

Journal: European journal of pharmacology 19921102

Title: Effect of excitatory amino acid receptor antagonists on apomorphine-, oxytocin- and ACTH-induced penile erection and yawning in male rats.

Journal: European journal of pharmacology 19920910

Title: The proconvulsive activity of quinolone antibiotics in an animal model.

Journal: Toxicology letters 19910901

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Tags:20263-07-4 Molecular Formula|20263-07-4 MDL|20263-07-4 SMILES|20263-07-4 DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID