518-44-5,MFCD00046931
Catalog No.:AA003QJ4

518-44-5 | Fluorescin

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Purity
Availability
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Quantity
  
1g
95%
in stock  
$152.00   $107.00
- +
5g
95%
in stock  
$418.00   $293.00
- +
10g
95%
in stock  
$760.00   $532.00
- +
25g
95%
in stock  
$1,677.00   $1,174.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003QJ4
Chemical Name:
Fluorescin
CAS Number:
518-44-5
Molecular Formula:
C20H14O5
Molecular Weight:
334.3222
MDL Number:
MFCD00046931
SMILES:
Oc1ccc2c(c1)Oc1c(C2c2ccccc2C(=O)O)ccc(c1)O
Properties
Properties
 
BP:
549.8°C at 760 mmHg  
Form:
Solid  
MP:
125-127°  
Refractive Index:
1.5000 (estimate)  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
469  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.7  

Downstream Synthesis Route

[1]v.Liebig[JournalfurpraktischeChemie(Leipzig1954),1912,vol.<2>85,p.255][ChemischeBerichte,1914,vol.47,p.2597]

[2]v.Liebig[JournalfurpraktischeChemie(Leipzig1954),1913,vol.<2>88,p.43]

[3]Baeyer[JustusLiebigsAnnalenderChemie,1876,vol.183,p.31][JustusLiebigsAnnalenderChemie,1910,vol.372,p.109]

[4]CurrentPatentAssignee:GENERALELECTRICCO-WO2006/65146,2006,A2Locationinpatent:Page/Pagecolumn19-20

[5]Le,HoaThi;Nguyen,DinhPhiLong;Shin,HyoSeob;Jung,Woong;Kang,Chulhun;Kim,TaeWoo[FreeRadicalResearch,2021,vol.55,#4,p.461-468]

[1]Sharma,PadamN.;Brossi,Arnold[HelveticaChimicaActa,1984,vol.<1>67,#35,p.301-304]

[2]Tadic,Dragana;Brossi,Arnold[Heterocycles,1990,vol.31,#11,p.1975-1982]

[1]Saengkhae,Chantarawan;Loetchutinat,Chatchanok;Garnier-Suillerot,Arlette[BiochemicalPharmacology,2003,vol.65,#6,p.969-977]

[2]Le,HoaThi;Nguyen,DinhPhiLong;Shin,HyoSeob;Jung,Woong;Kang,Chulhun;Kim,TaeWoo[FreeRadicalResearch,2021,vol.55,#4,p.461-468]

[1]Ou,Pan;Zhang,Ruilong;Liu,Zhengjie;Tian,Xiaohe;Han,Guangmei;Liu,Bianhua;Hu,Zhangjun;Zhang,Zhongping[AngewandteChemie-InternationalEdition,2019,vol.58,#8,p.2261-2265][Angew.Chem.,2019,vol.131,#8,p.2283-2287,5]

Literature

Title: (-)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells.

Journal: Journal of neuroinflammation 20120101

Title: [Serotyping and analysis of produced pigments kinds by Pseudomonas aeruginosa clinical isolates].

Journal: Vojnosanitetski pregled 20111101

Title: Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathway.

Journal: PloS one 20110101

Title: Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish.

Journal: PloS one 20110101

Title: Recurring meningoencephalitis in sinusitis-associated acute posterior multifocal placoid pigment epitheliopathy under prednisone tapering.

Journal: BMJ case reports 20110101

Title: Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.

Journal: Diabetes 20100401

Title: Human interphase chromosomes: a review of available molecular cytogenetic technologies.

Journal: Molecular cytogenetics 20100101

Title: Cardiac deletion of Smyd2 is dispensable for mouse heart development.

Journal: PloS one 20100101

Title: Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa.

Journal: BMC genomics 20100101

Title: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury.

Journal: Critical care (London, England) 20100101

Title: Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer.

Journal: BMC cancer 20100101

Title: Intracranial hypertension: A rare presentation of lupus nephritis.

Journal: Journal of pediatric neurosciences 20100101

Title: Reduced fluoresceinamine as a fluorescent sensor for nitric oxide.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Fluorophotometric determination of hydrogen peroxide with fluorescin in the presence of cobalt (II) and reaction against other reactive oxygen species.

Journal: Journal of fluorescence 20090901

Title: [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090701

Title: Retinal pathology of pediatric cerebral malaria in Malawi.

Journal: PloS one 20090101

Title: Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis.

Journal: Critical care (London, England) 20090101

Title: Anchoring secreted proteins in endoplasmic reticulum by plant oleosin: the example of vitamin B12 cellular sequestration by transcobalamin.

Journal: PloS one 20090101

Title: An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells.

Journal: Chemistry Central journal 20090101

Title: Use of endobronchial one-way valves reveals questions on etiology of spontaneous pneumothorax: report of three cases.

Journal: Journal of cardiothoracic surgery 20090101

Title: Biomaterials in skull base surgery.

Journal: GMS current topics in otorhinolaryngology, head and neck surgery 20090101

Title: Role of Peoxisome Proliferator Activator Receptor gamma on Blood Retinal Barrier Breakdown.

Journal: PPAR research 20080101

Title: Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development.

Journal: BMC developmental biology 20080101

Title: Surfactant protein-A inhibits Aspergillus fumigatus-induced allergic T-cell responses.

Journal: Respiratory research 20050101

Title: Conditional immune-gene suppression of honeybees parasitized by Varroa mites.

Journal: Journal of insect science (Online) 20050101

Title: [Quantitation and detection of deletion in tumor mitochondrial DNA by microarray technique].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20040101

Title: Ship-in-a-bottle synthesis of fluorescence-labeled nanoparticles: applications in cellular imaging.

Journal: Photochemistry and photobiology 20040101

Title: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.

Journal: Pharmaceutical research 20030401

Title: Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol.

Journal: Proteins 19890101

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Additional Info:
SDS
Tags:518-44-5 Molecular Formula|518-44-5 MDL|518-44-5 SMILES|518-44-5 Fluorescin
Catalog No.: AA003QJ4
518-44-5,MFCD00046931
518-44-5 | Fluorescin
Pack Size: 1g
Purity: 95%
in stock
$152.00 $107.00
Pack Size: 5g
Purity: 95%
in stock
$418.00 $293.00
Pack Size: 10g
Purity: 95%
in stock
$760.00 $532.00
Pack Size: 25g
Purity: 95%
in stock
$1,677.00 $1,174.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003QJ4
Chemical Name: Fluorescin
CAS Number: 518-44-5
Molecular Formula: C20H14O5
Molecular Weight: 334.3222
MDL Number: MFCD00046931
SMILES: Oc1ccc2c(c1)Oc1c(C2c2ccccc2C(=O)O)ccc(c1)O
Properties
BP: 549.8°C at 760 mmHg  
Form: Solid  
MP: 125-127°  
Refractive Index: 1.5000 (estimate)  
Storage: Room Temperature;Keep in dry area;  
Complexity: 469  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.7  
Downstream Synthesis Route
2321-07-5    518-44-5 

[1]v.Liebig[JournalfurpraktischeChemie(Leipzig1954),1912,vol.<2>85,p.255][ChemischeBerichte,1914,vol.47,p.2597]

[2]v.Liebig[JournalfurpraktischeChemie(Leipzig1954),1913,vol.<2>88,p.43]

[3]Baeyer[JustusLiebigsAnnalenderChemie,1876,vol.183,p.31][JustusLiebigsAnnalenderChemie,1910,vol.372,p.109]

[4]CurrentPatentAssignee:GENERALELECTRICCO-WO2006/65146,2006,A2Locationinpatent:Page/Pagecolumn19-20

[5]Le,HoaThi;Nguyen,DinhPhiLong;Shin,HyoSeob;Jung,Woong;Kang,Chulhun;Kim,TaeWoo[FreeRadicalResearch,2021,vol.55,#4,p.461-468]

518-44-5    108-24-7    35340-49-9 

[1]Sharma,PadamN.;Brossi,Arnold[HelveticaChimicaActa,1984,vol.<1>67,#35,p.301-304]

[2]Tadic,Dragana;Brossi,Arnold[Heterocycles,1990,vol.31,#11,p.1975-1982]

35340-49-9    518-44-5 

[1]Saengkhae,Chantarawan;Loetchutinat,Chatchanok;Garnier-Suillerot,Arlette[BiochemicalPharmacology,2003,vol.65,#6,p.969-977]

[2]Le,HoaThi;Nguyen,DinhPhiLong;Shin,HyoSeob;Jung,Woong;Kang,Chulhun;Kim,TaeWoo[FreeRadicalResearch,2021,vol.55,#4,p.461-468]

518-44-5    2513-33-9 

[1]Ou,Pan;Zhang,Ruilong;Liu,Zhengjie;Tian,Xiaohe;Han,Guangmei;Liu,Bianhua;Hu,Zhangjun;Zhang,Zhongping[AngewandteChemie-InternationalEdition,2019,vol.58,#8,p.2261-2265][Angew.Chem.,2019,vol.131,#8,p.2283-2287,5]

Literature fold

Title: (-)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells.

Journal: Journal of neuroinflammation20120101

Title: [Serotyping and analysis of produced pigments kinds by Pseudomonas aeruginosa clinical isolates].

Journal: Vojnosanitetski pregled20111101

Title: Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathway.

Journal: PloS one20110101

Title: Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish.

Journal: PloS one20110101

Title: Recurring meningoencephalitis in sinusitis-associated acute posterior multifocal placoid pigment epitheliopathy under prednisone tapering.

Journal: BMJ case reports20110101

Title: Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.

Journal: Diabetes20100401

Title: Human interphase chromosomes: a review of available molecular cytogenetic technologies.

Journal: Molecular cytogenetics20100101

Title: Cardiac deletion of Smyd2 is dispensable for mouse heart development.

Journal: PloS one20100101

Title: Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa.

Journal: BMC genomics20100101

Title: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury.

Journal: Critical care (London, England)20100101

Title: Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer.

Journal: BMC cancer20100101

Title: Intracranial hypertension: A rare presentation of lupus nephritis.

Journal: Journal of pediatric neurosciences20100101

Title: Reduced fluoresceinamine as a fluorescent sensor for nitric oxide.

Journal: Sensors (Basel, Switzerland)20100101

Title: Fluorophotometric determination of hydrogen peroxide with fluorescin in the presence of cobalt (II) and reaction against other reactive oxygen species.

Journal: Journal of fluorescence20090901

Title: [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20090701

Title: Retinal pathology of pediatric cerebral malaria in Malawi.

Journal: PloS one20090101

Title: Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis.

Journal: Critical care (London, England)20090101

Title: Anchoring secreted proteins in endoplasmic reticulum by plant oleosin: the example of vitamin B12 cellular sequestration by transcobalamin.

Journal: PloS one20090101

Title: An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells.

Journal: Chemistry Central journal20090101

Title: Use of endobronchial one-way valves reveals questions on etiology of spontaneous pneumothorax: report of three cases.

Journal: Journal of cardiothoracic surgery20090101

Title: Biomaterials in skull base surgery.

Journal: GMS current topics in otorhinolaryngology, head and neck surgery20090101

Title: Role of Peoxisome Proliferator Activator Receptor gamma on Blood Retinal Barrier Breakdown.

Journal: PPAR research20080101

Title: Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development.

Journal: BMC developmental biology20080101

Title: Surfactant protein-A inhibits Aspergillus fumigatus-induced allergic T-cell responses.

Journal: Respiratory research20050101

Title: Conditional immune-gene suppression of honeybees parasitized by Varroa mites.

Journal: Journal of insect science (Online)20050101

Title: [Quantitation and detection of deletion in tumor mitochondrial DNA by microarray technique].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20040101

Title: Ship-in-a-bottle synthesis of fluorescence-labeled nanoparticles: applications in cellular imaging.

Journal: Photochemistry and photobiology20040101

Title: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.

Journal: Pharmaceutical research20030401

Title: Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol.

Journal: Proteins19890101

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