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721-66-4,MFCD00065109
Catalog No.:AA003QPX

721-66-4 | 2-(2-Aminoacetamido)-3-phenylpropanoic acid

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100mg
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$11.00   $8.00
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250mg
98+%
in stock  
$15.00   $11.00
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1g
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$25.00   $18.00
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5g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003QPX
Chemical Name:
2-(2-Aminoacetamido)-3-phenylpropanoic acid
CAS Number:
721-66-4
Molecular Formula:
C11H14N2O3
Molecular Weight:
222.2405
MDL Number:
MFCD00065109
SMILES:
NCC(=O)NC(C(=O)O)Cc1ccccc1
Properties
Properties
 
BP:
492.2°C at 760 mmHg  
Form:
Solid  
MP:
273-275℃ (Decomposition)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
250  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-2.7  

Downstream Synthesis Route
copper(II)nitratetrihydrate 
  721-66-4    59-51-8   
potassiumhydroxide 
 
Cu(GlyLeu)Met(H2O)2K*H2O 

[1]Polyhedron,2013,vol.54,p.34-38

Literature

Title: Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.

Journal: Molecular pharmaceutics 20120904

Title: Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity.

Journal: Journal of biomolecular screening 20110101

Title: Covalent immobilisation of protease and laccase substrates onto siloxanes.

Journal: Chemosphere 20100801

Title: Riboflavin-binding protein is a novel bitter inhibitor.

Journal: Chemical senses 20080101

Title: Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length.

Journal: Bioscience, biotechnology, and biochemistry 20070801

Title: Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.

Journal: Biochemistry 20050802

Title: Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.

Journal: Biochemistry 20050802

Title: Spontaneous resolution of binary copper(II) complexes with racemic dipeptides: crystal structures of glycyl-L-alpha-amino-n-butyrato copper(II) monohydrate, glycyl-D-valinato copper(II) hemihydrate, and glycyl-L-valinato copper(II) hemihydrate.

Journal: Journal of inorganic biochemistry 20050801

Title: Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly.

Journal: Archives of biochemistry and biophysics 20050301

Title: Intrinsic folding of small peptide chains: spectroscopic evidence for the formation of beta-turns in the gas phase.

Journal: Journal of the American Chemical Society 20050119

Title: Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040801

Title: Lanthanide ion-mediated peptide hydrolysis.

Journal: Metal ions in biological systems 20010101

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SDS
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