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87-52-5,MFCD00005629
Catalog No.:AA003QQN

87-52-5 | 3-(Dimethylaminomethyl)indole

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5g
98%(HPLC)
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$29.00   $20.00
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25g
98%
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$35.00   $25.00
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250g
>98.0%(T)
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003QQN
Chemical Name:
3-(Dimethylaminomethyl)indole
CAS Number:
87-52-5
Molecular Formula:
C11H14N2
Molecular Weight:
174.2423
MDL Number:
MFCD00005629
SMILES:
CN(Cc1c[nH]c2c1cccc2)C
NSC Number:
16892
Properties
Properties
 
BP:
293.9 °C at 760 mmHg  
Form:
Solid  
MP:
132-134 °C(lit.)  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
168  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.8  

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Influence of saponins and tannins on intake and nutrient digestion of alkaloid-containing foods.

Journal: Journal of the science of food and agriculture 20120830

Title: Heterocycle-functional gramine analogues: solvent- and catalyst-free synthesis and their inhibition activities against cell proliferation.

Journal: European journal of medicinal chemistry 20120801

Title: rac-4-{(E)-[1-Cyano-1-cyclo-hexyl-2-(1H-indol-3-yl)eth-yl]imino-meth-yl}benzonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: [(5-Bromo-1H-indol-3-yl)meth-yl]dimethyl-aza-nium nitrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Found in translation: high-throughput chemical screening in Arabidopsis thaliana identifies small molecules that reduce Fusarium head blight disease in wheat.

Journal: Molecular plant-microbe interactions : MPMI 20110601

Title: Improved synthesis of 3-(dialkylaminomethyl)-indole in acetic acid aqueous solution under ultrasound irradiation.

Journal: Ultrasonics sonochemistry 20110101

Title: Differential regulation of 3-aminomethylindole/N-methyl-3-aminomethylindole N-methyltransferase and gramine in barley by both biotic and abiotic stress conditions.

Journal: Plant physiology and biochemistry : PPB 20110101

Title: A GFP-based assay to quantify the impact of effectors on the ex planta development of the slowly growing barley pathogen Rhynchosporium commune.

Journal: Mycologia 20110101

Title: The gramine route to pyrido[4,3-b]indol-3-ones - identification of a new cytotoxic lead.

Journal: Scientia pharmaceutica 20110101

Title: Allele mining in barley genetic resources reveals genes of race-non-specific powdery mildew resistance.

Journal: Frontiers in plant science 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Classification of rice (Oryza sativa L. Japonica nipponbare) immunophilins (FKBPs, CYPs) and expression patterns under water stress.

Journal: BMC plant biology 20100101

Title: Operons.

Journal: Cellular and molecular life sciences : CMLS 20091201

Title: Detoxification of gramine by the cereal aphid Sitobion avenae.

Journal: Journal of chemical ecology 20090301

Title: Gramine-induced growth inhibition, oxidative damage and antioxidant responses in freshwater cyanobacterium Microcystis aeruginosa.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090219

Title: Annotation and expression of carboxylesterases in the silkworm, Bombyx mori.

Journal: BMC genomics 20090101

Title: Oxidation of suspected N-nitrosodimethylamine (NDMA) precursors by ferrate (VI): kinetics and effect on the NDMA formation potential of natural waters.

Journal: Water research 20080101

Title: A role for gene duplication and natural variation of gene expression in the evolution of metabolism.

Journal: PloS one 20080101

Title: An antidepressant that extends lifespan in adult Caenorhabditis elegans.

Journal: Nature 20071122

Title: Naphthoindole-based analogues of tryptophan and tryptamine: synthesis and cytotoxic properties.

Journal: Bioorganic & medicinal chemistry 20070401

Title: Synthesis of N-protected staurosporinones.

Journal: The Journal of organic chemistry 20070316

Title: Benzylic substitution of gramines with boronic acids and rhodium or iridium catalysts.

Journal: Organic letters 20070315

Title: Efficient and sensitive method for quantitative analysis of alkaloids in hardinggrass (Phalaris aquatica L.).

Journal: Journal of agricultural and food chemistry 20061213

Title: N-Methyltransferase involved in gramine biosynthesis in barley: cloning and characterization.

Journal: Phytochemistry 20060901

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Evolution of the indole alkaloid biosynthesis in the genus Hordeum: distribution of gramine and DIBOA and isolation of the benzoxazinoid biosynthesis genes from Hordeum lechleri.

Journal: Phytochemistry 20050601

Title: Do naïve ruminants degrade alkaloids in the rumen?

Journal: Journal of chemical ecology 20050401

Title: Gramine: a vasorelaxing alkaloid acting on 5-HT(2A) receptors.

Journal: Planta medica 20040401

Title: Further characterization of pigment-producing Malassezia strains.

Journal: Mycoses 20040201

Title: Asymmetric, stereocontrolled total synthesis of paraherquamide A.

Journal: Journal of the American Chemical Society 20031008

Title: N1-benzenesulfonylgramine and N1-benzenesulfonylskatole: novel 5-HT6 receptor ligand templates.

Journal: Bioorganic & medicinal chemistry letters 20031006

Title: Activation of MMP-2, cleavage of matrix proteins, and adherens junctions during a snake venom metalloproteinase-induced endothelial cell apoptosis.

Journal: Experimental cell research 20030801

Title: Convenient synthesis of 5,6,11,12,17,18- hexahydrocyclononal[1,2-b:4,5-b':7,8-b'']triindole, a novel phytoestrogen.

Journal: The Journal of organic chemistry 20030110

Title: Serotonin regulates repolarization of the C. elegans pharyngeal muscle.

Journal: The Journal of experimental biology 20030101

Title: Octopaminergic agonists for the cockroach neuronal octopamine receptor.

Journal: Journal of insect science (Online) 20030101

Title: Diastereoselective reactions in glycine templates containing an ent-ardeemin fragment.

Journal: The Journal of organic chemistry 20020405

Title: Rapid route to 3,4-substituted indoles via a directed ortho metalation-retro-Mannich sequence.

Journal: Organic letters 20020307

Title: Novel marine-derived halogen-containing gramine analogues induce vasorelaxation in isolated rat aorta.

Journal: European journal of pharmacology 20011130

Title: Gramine increase associated with rapid and transient systemic resistance in barley seedlings induced by mechanical and biological stresses.

Journal: Plant & cell physiology 20011001

Title: Purification, molecular cloning and mechanism of action of graminelysin I, a snake-venom-derived metalloproteinase that induces apoptosis of human endothelial cells.

Journal: The Biochemical journal 20010801

Title: Differential inhibition of [3H]-oxotremorine-M and [3H]-quinuclinidyl benzilate binding to muscarinic receptors in rat brain membranes with acetylcholinesterase inhibitors.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010401

Title: Response of animals to dietary gramine. I. Performance and selected hematological, biochemical and histological parameters in growing chicken, rats and pigs.

Journal: Archiv fur Tierernahrung 20010101

Title: Response of animals to dietary gramine. II. Effects of feeding high-gramine yellow lupin seeds on reproductive performance of rats and on selected hematological and biochemical parameters in offspring.

Journal: Archiv fur Tierernahrung 20010101

Title: [Antimycobacterial indole derivatives].

Journal: Archiv der Pharmazie 19940201

Title: Sun Y, et al. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay. PLoS One. 2013 May 14;8(5):e63354.

Title: Chikazawa M, et al. Identification of Functional Food Factors as β2-Adrenergic Receptor Agonists and Their Potential Roles in Skeletal Muscle. J Nutr Sci Vitaminol (Tokyo). 2018;64(1):68-74.

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Tags:87-52-5 Molecular Formula|87-52-5 MDL|87-52-5 SMILES|87-52-5 3-(Dimethylaminomethyl)indole