Title: Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells.
Journal: Journal of molecular medicine (Berlin, Germany)20120201
Title: ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20110501
Title: A tagging-via-substrate approach to detect the farnesylated proteome using two-dimensional electrophoresis coupled with Western blotting.
Journal: Molecular & cellular proteomics : MCP20100401
Title: Development of farnesyl transferase inhibitors: a review.
Journal: The oncologist20050901
Title: Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications.
Journal: Current drug targets20050501
Title: [Farnesyltransferase inhibitors: preliminary results in acute myeloid leukemia].
Journal: Bulletin du cancer20050301
Title: Inhibition of lymphocyte activation and function by the prenylation inhibitor L-778,123.
Journal: Investigational new drugs20050101
Title: Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes.
Journal: Biochemistry20040720
Title: Farnesyl transferase inhibitors for patients with lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20040615
Title: [Ras signaling pathway as a target for farnesyltransferase inhibitors--a new, promising prospects in the treatment for malignant disorders].
Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960)20040101
Title: Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
Journal: Oncogene20030918
Title: Farnesyltransferase inhibitors as radiation sensitizers.
Journal: International journal of radiation biology20030701
Title: Farnesyl transferase inhibitors in the treatment of breast cancer.
Journal: Expert opinion on investigational drugs20030301
Title: The effects of the farnesyl transferase inhibitor FTI L-778,123 on normal, myelodysplastic, and myeloid leukemia bone marrow progenitor proliferation in vitro.
Journal: Leukemia & lymphoma20030101
Title: Farnesyl transferase inhibitors as anticancer agents.
Journal: European journal of cancer (Oxford, England : 1990)20020901
Title: A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20011201
Title: Ras inhibitors and radiation therapy.
Journal: Seminars in radiation oncology20011001
Title: Farnesyltransferase inhibitors.
Journal: Seminars in oncology20011001
Title: Anions modulate the potency of geranylgeranyl-protein transferase I inhibitors.
Journal: The Journal of biological chemistry20010706
Title: High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123.
Journal: Analytical biochemistry20010301
Title: Lobell RB, et al. Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I. Mol Cancer Ther. 2002 Jul;1(9):747-758.
Title: Ghasemi S, et al. Comparison of Cytotoxic Activity of L778123 as a Farnesyltranferase Inhibitor and Doxorubicin against A549 and HT-29 Cell Lines. Adv Pharm Bull. 2013;3(1):73-77.
