64953-12-4,MFCD03427565
Catalog No.:AA003R5G

64953-12-4 | Latamoxef sodium

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$39.00   $27.00
- +
250mg
95%
in stock  
$75.00   $53.00
- +
500mg
95%
in stock  
$140.00   $98.00
- +
1g
≥85%
in stock  
$166.00   $117.00
- +
5g
≥85%
in stock  
$545.00   $382.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003R5G
Chemical Name:
Latamoxef sodium
CAS Number:
64953-12-4
Molecular Formula:
C20H18N6Na2O9S
Molecular Weight:
564.4363
MDL Number:
MFCD03427565
SMILES:
COC1(NC(=O)C(c2ccc(cc2)O)C(=O)[O-])C(=O)N2C1OCC(=C2C(=O)[O-])CSc1nnnn1C.[Na+].[Na+]
Properties
Properties
 
Form:
Solid  
MP:
>156ºC (dec.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
947  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: [Comparison of oxacillin, cefoxitin, ceftizoxime, and moxalactam disk diffusion methods for detection of methicillin susceptibility in staphylococci].

Journal: Mikrobiyoloji bulteni 20110401

Title: Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70.

Journal: The Biochemical journal 20101215

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Improved measurement of drug exposure in the brain using drug-specific correction for residual blood.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100101

Title: Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.

Journal: Journal of molecular biology 20080104

Title: Structural basis for the role of Asp-120 in metallo-beta-lactamases.

Journal: Biochemistry 20070918

Title: Antibiotic deactivation by a dizinc beta-lactamase: mechanistic insights from QM/MM and DFT studies.

Journal: Journal of the American Chemical Society 20070905

Title: The effect of annealing on the stability of amorphous solids: chemical stability of freeze-dried moxalactam.

Journal: Journal of pharmaceutical sciences 20070501

Title: Comparison of cefoxitin and moxalactam 30 microg disc diffusion methods for detection of methicillin resistance in coagulase-negative staphylococci.

Journal: The Journal of antimicrobial chemotherapy 20070401

Title: Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography.

Journal: Journal of the American Chemical Society 20051019

Title: A theoretical study on the substrate deacylation mechanism of class C beta-lactamase.

Journal: The journal of physical chemistry. B 20050825

Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Journal: Journal of pharmaceutical sciences 20050701

Title: Lysis-deficient bacteriophage therapy decreases endotoxin and inflammatory mediator release and improves survival in a murine peritonitis model.

Journal: Surgery 20050601

Title: Sourcing faecal pollution from onsite wastewater treatment systems in surface waters using antibiotic resistance analysis.

Journal: Journal of applied microbiology 20050101

Title: Trace determination of shiomarin using a hanging copper/amalgam drop electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20020620

Title: Noncovalent interaction energies in covalent complexes: TEM-1 beta-lactamase and beta-lactams.

Journal: Proteins 20020401

Title: Phosphate deprivation is associated with high resistance to latamoxef of gel-entrapped, sessile-like Escherichia coli cells.

Journal: The Journal of antimicrobial chemotherapy 20020201

Title: Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site.

Journal: Biochemistry 20010710

Title: Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam.

Journal: European journal of biochemistry 20010701

Title: Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation.

Journal: Protein science : a publication of the Protein Society 20010601

Title: [A case of hematuria associated with cefem group antibiotics].

Journal: Hinyokika kiyo. Acta urologica Japonica 19920201

Title: Enhanced bleeding with cefoxitin or moxalactam. Statistical analysis within a defined population of 1493 patients.

Journal: Archives of internal medicine 19861101

Title: Studies on the nephrotoxicity of aminoglycoside antibiotics and protection from these effects (3). Protective effect of latamoxef against tobramycin nephrotoxicity and its protective mechanism.

Journal: Japanese journal of pharmacology 19861101

Title: A double beta-lactam combination versus an aminoglycoside-containing regimen as empiric antibiotic therapy for febrile granulocytopenic cancer patients.

Journal: The American journal of medicine 19860530

Title: Moxalactam myoclonus, seizures, and encephalopathy.

Journal: Drug intelligence & clinical pharmacy 19860301

Title: Specificity of renal tubular damage criteria for aminoglycoside nephrotoxicity in critically ill patients.

Journal: Journal of clinical pharmacology 19831001

Title: Enterococcal liver abscess associated with moxalactam therapy. Review of literature on enterococcal superinfections in association with moxalactam therapy.

Journal: Archives of internal medicine 19830901

Title: Third-generation cephalosporins for polymicrobial surgical sepsis.

Journal: Archives of surgery (Chicago, Ill. : 1960) 19830201

Title: Prolonged bleeding times and bleeding diathesis associated with moxalactam administration.

Journal: JAMA 19830107

Title: A single injection of moxalactam for acute gonorrhea.

Journal: Clinical therapeutics 19830101

Title: Evaluation of lamoxactam in the treatment of severe bacterial infections.

Journal: Chemotherapy 19830101

Title: Carmine AA, et al. Moxalactam (latamoxef). A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1983 Oct;26(4):279-333.

Title: Goto S. In vitro and in vivo antibacterial activity of moxalactam, an oxa-β-lactam antibiotic. Clinical Infectious Diseases, 1982, 4(Supplement_3): S501-S510.

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SDS
Related Products of 64953-12-4
Tags:64953-12-4 Molecular Formula|64953-12-4 MDL|64953-12-4 SMILES|64953-12-4 Latamoxef sodium
Catalog No.: AA003R5G
64953-12-4,MFCD03427565
64953-12-4 | Latamoxef sodium
Pack Size: 100mg
Purity: 95%
in stock
$39.00 $27.00
Pack Size: 250mg
Purity: 95%
in stock
$75.00 $53.00
Pack Size: 500mg
Purity: 95%
in stock
$140.00 $98.00
Pack Size: 1g
Purity: ≥85%
in stock
$166.00 $117.00
Pack Size: 5g
Purity: ≥85%
in stock
$545.00 $382.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003R5G
Chemical Name: Latamoxef sodium
CAS Number: 64953-12-4
Molecular Formula: C20H18N6Na2O9S
Molecular Weight: 564.4363
MDL Number: MFCD03427565
SMILES: COC1(NC(=O)C(c2ccc(cc2)O)C(=O)[O-])C(=O)N2C1OCC(=C2C(=O)[O-])CSc1nnnn1C.[Na+].[Na+]
Properties
Form: Solid  
MP: >156ºC (dec.)  
Storage: Inert atmosphere;2-8℃;  
Complexity: 947  
Covalently-Bonded Unit Count: 3  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 38  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 1  
Literature fold

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology20111201

Title: [Comparison of oxacillin, cefoxitin, ceftizoxime, and moxalactam disk diffusion methods for detection of methicillin susceptibility in staphylococci].

Journal: Mikrobiyoloji bulteni20110401

Title: Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70.

Journal: The Biochemical journal20101215

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Improved measurement of drug exposure in the brain using drug-specific correction for residual blood.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism20100101

Title: Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.

Journal: Journal of molecular biology20080104

Title: Structural basis for the role of Asp-120 in metallo-beta-lactamases.

Journal: Biochemistry20070918

Title: Antibiotic deactivation by a dizinc beta-lactamase: mechanistic insights from QM/MM and DFT studies.

Journal: Journal of the American Chemical Society20070905

Title: The effect of annealing on the stability of amorphous solids: chemical stability of freeze-dried moxalactam.

Journal: Journal of pharmaceutical sciences20070501

Title: Comparison of cefoxitin and moxalactam 30 microg disc diffusion methods for detection of methicillin resistance in coagulase-negative staphylococci.

Journal: The Journal of antimicrobial chemotherapy20070401

Title: Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography.

Journal: Journal of the American Chemical Society20051019

Title: A theoretical study on the substrate deacylation mechanism of class C beta-lactamase.

Journal: The journal of physical chemistry. B20050825

Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Journal: Journal of pharmaceutical sciences20050701

Title: Lysis-deficient bacteriophage therapy decreases endotoxin and inflammatory mediator release and improves survival in a murine peritonitis model.

Journal: Surgery20050601

Title: Sourcing faecal pollution from onsite wastewater treatment systems in surface waters using antibiotic resistance analysis.

Journal: Journal of applied microbiology20050101

Title: Trace determination of shiomarin using a hanging copper/amalgam drop electrode.

Journal: Journal of pharmaceutical and biomedical analysis20020620

Title: Noncovalent interaction energies in covalent complexes: TEM-1 beta-lactamase and beta-lactams.

Journal: Proteins20020401

Title: Phosphate deprivation is associated with high resistance to latamoxef of gel-entrapped, sessile-like Escherichia coli cells.

Journal: The Journal of antimicrobial chemotherapy20020201

Title: Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site.

Journal: Biochemistry20010710

Title: Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam.

Journal: European journal of biochemistry20010701

Title: Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation.

Journal: Protein science : a publication of the Protein Society20010601

Title: [A case of hematuria associated with cefem group antibiotics].

Journal: Hinyokika kiyo. Acta urologica Japonica19920201

Title: Enhanced bleeding with cefoxitin or moxalactam. Statistical analysis within a defined population of 1493 patients.

Journal: Archives of internal medicine19861101

Title: Studies on the nephrotoxicity of aminoglycoside antibiotics and protection from these effects (3). Protective effect of latamoxef against tobramycin nephrotoxicity and its protective mechanism.

Journal: Japanese journal of pharmacology19861101

Title: A double beta-lactam combination versus an aminoglycoside-containing regimen as empiric antibiotic therapy for febrile granulocytopenic cancer patients.

Journal: The American journal of medicine19860530

Title: Moxalactam myoclonus, seizures, and encephalopathy.

Journal: Drug intelligence & clinical pharmacy19860301

Title: Specificity of renal tubular damage criteria for aminoglycoside nephrotoxicity in critically ill patients.

Journal: Journal of clinical pharmacology19831001

Title: Enterococcal liver abscess associated with moxalactam therapy. Review of literature on enterococcal superinfections in association with moxalactam therapy.

Journal: Archives of internal medicine19830901

Title: Third-generation cephalosporins for polymicrobial surgical sepsis.

Journal: Archives of surgery (Chicago, Ill. : 1960)19830201

Title: Prolonged bleeding times and bleeding diathesis associated with moxalactam administration.

Journal: JAMA19830107

Title: A single injection of moxalactam for acute gonorrhea.

Journal: Clinical therapeutics19830101

Title: Evaluation of lamoxactam in the treatment of severe bacterial infections.

Journal: Chemotherapy19830101

Title: Carmine AA, et al. Moxalactam (latamoxef). A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1983 Oct;26(4):279-333.

Title: Goto S. In vitro and in vivo antibacterial activity of moxalactam, an oxa-β-lactam antibiotic. Clinical Infectious Diseases, 1982, 4(Supplement_3): S501-S510.

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