6600-40-4,MFCD00064421
Catalog No.:AA003RA8

6600-40-4 | L-Norvaline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$11.00   $8.00
- +
5g
97%
in stock  
$13.00   $9.00
- +
10g
97%
in stock  
$18.00   $13.00
- +
25g
97%
in stock  
$34.00   $24.00
- +
100g
97%
in stock  
$47.00   $33.00
- +
500g
97%
in stock  
$57.00   $40.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003RA8
Chemical Name:
L-Norvaline
CAS Number:
6600-40-4
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00064421
SMILES:
CCC[C@@H](C(=O)O)N
Properties
Properties
 
Form:
Solid  
MP:
>300 °C(lit.)  
Refractive Index:
25 ° (C=10, 6mol/L HCl)  
Solubility:
48.7g/l  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
82.5  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-2.1  

Upstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#18,p.8126-8132

[1]JournaloftheAmericanChemicalSociety,1984,vol.106,#5,p.1490-1491

[2]JournaloftheAmericanChemicalSociety,1986,vol.108,#8,p.1969-1979

[3]OrganicLetters,2016,vol.18,#15,p.3658-3661

[1]JournalofOrganicChemistry,1994,vol.59,#25,p.7580-7581

[2]JournaloftheChineseChemicalSociety,1999,vol.46,#3,p.301-311

[1]OrganicLetters,2010,vol.12,#9,p.1916-1919

[1]Tetrahedron,1980,vol.36,#81,p.1089-1098

[2]Tetrahedron,1980,vol.36,#81,p.1089-1098

[3]Tetrahedron,1980,vol.36,#81,p.1089-1098

[4]Tetrahedron,1980,vol.36,#81,p.1089-1098

Downstream Synthesis Route

[1]Fernández,Ariadna;Díaz,JoséLuis;García,Mónica;Rodríguez-Escrich,Sergi;Lorente,Adriana;Enrech,Raquel;Dordal,Albert;Portillo-Salido,Enrique;Porras,Mónica;Fernández,Begoña;Reinoso,RaquelF.;Vela,JoséMiguel;Almansa,Carmen[ACSMedicinalChemistryLetters,2021,vol.12,#11,p.1802-1809]

[2]Mori,Kenji;Takaishi,Hideo[Tetrahedron,1989,vol.45,#6,p.1639-1646]

[3]Winitzetal.[JournaloftheAmericanChemicalSociety,1956,vol.78,p.2423,2428]

[4]Baker;Meister[JournaloftheAmericanChemicalSociety,1951,vol.73,p.1336]

[5]Nakamura,Kaoru;Inoue,Kiyoko;Ushio,Kazutoshi;Oka,Shinzaburo;Ohno,Atsuyoshi[JournalofOrganicChemistry,1988,vol.53,#11,p.2589-2593]

[6]Raddatz,Peter;Minck,Klaus-Otto;Rippmann,Friedrich;Schmitges,Claus-Jochen[JournalofMedicinalChemistry,1994,vol.37,#4,p.486-497]

[1]JournalofBiochemistry,1959,vol.46,p.19,21

[1]AngewandteChemie,1992,vol.104,p.97-99

[2]Synthesis,2010,p.2915-2921

[3]Patent:WO2013/136265,2013,A1.Locationinpatent:Page/Pagecolumn21-22

[4]Patent:WO2004/33434,2004,A1.Locationinpatent:Page34

[5]Heterocycles,1998,vol.47,p.765-780

[6]Phytochemistry,1988,vol.27,p.77-84

[7]EuropeanJournalofOrganicChemistry,2002,p.3763-3767

[8]Patent:WO2006/44775,2006,A2.Locationinpatent:Page/Pagecolumn36

[9]JournalofMedicinalChemistry,2017,vol.60,p.5889-5908

[1]JournaloftheAmericanChemicalSociety,1980,vol.102,p.5115-5117

[2]CatalysisLetters,2018,vol.148,p.3678-3684

[1]Tetrahedron,1991,vol.47,p.5453-5462

Literature

Title: Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps.

Journal: The Journal of biological chemistry 20120720

Title: Glutamine and glutathione at ICU admission in relation to outcome.

Journal: Clinical science (London, England : 1979) 20120601

Title: Metabolome analysis of gram-positive bacteria such as Staphylococcus aureus by GC-MS and LC-MS.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production.

Journal: Vascular pharmacology 20120101

Title: New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.

Journal: PloS one 20120101

Title: Combination of valproate and paroxetine in mice exposed to picrotoxin.

Journal: International journal of nanomedicine 20120101

Title: Jadomycins derived from the assimilation and incorporation of norvaline and norleucine.

Journal: Journal of natural products 20111128

Title: An evolutionary strategy for isobutanol production strain development in Escherichia coli.

Journal: Metabolic engineering 20111101

Title: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.

Journal: The FEBS journal 20110901

Title: Understanding the molecular dynamics associated with polymorphic transitions of DL-norvaline with solid-state NMR methods.

Journal: The journal of physical chemistry. B 20110331

Title: Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction.

Journal: The journal of physical chemistry. B 20110317

Title: A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum.

Journal: BMC microbiology 20110101

Title: Arginase inhibitor in the pharmacological correction of endothelial dysfunction.

Journal: International journal of hypertension 20110101

Title: Establishment of reference range of plasma amino acids for younger Chinese children by reverse phase HPLC.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Ligand-induced changes in the conformational stability and flexibility of glutamate dehydrogenase and their role in catalysis and regulation.

Journal: Protein science : a publication of the Protein Society 20101001

Title: RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis.

Journal: Plant molecular biology 20100901

Title: Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice.

Journal: Heart and vessels 20100501

Title: A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.

Journal: Journal of medicinal chemistry 20100211

Title: Specificities of olfactory receptor neuron responses to amino acids in the black bullhead catfish (Ameiurus melas).

Journal: Pflugers Archiv : European journal of physiology 20100201

Title: Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy.

Journal: The journal of physical chemistry. B 20100128

Title: Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

Journal: Toxicology and applied pharmacology 20090901

Title: Kinetic and thermodynamic control in the stereoselective formation of trans- and cis-2-ferrocenyl-3-pivaloyl-4-alkyl-1,3-oxazolidin-5-ones.

Journal: Organic & biomolecular chemistry 20090207

Title: Cyclosporins from Mycelium sterilae MS 2929.

Journal: Journal of natural products 20090101

Title: Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline.

Journal: BMC cardiovascular disorders 20090101

Title: A 3(10)-helical pentapeptide in water: interplay of alpha,alpha-disubstituted amino acids and the central residue on structure formation.

Journal: Biopolymers 20090101

Title: The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.

Journal: Journal of molecular biology 20080125

Title: Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.

Journal: BMC biochemistry 20080101

Title: Enzymatic evidence for the key role of arginine in nitrogen translocation by arbuscular mycorrhizal fungi.

Journal: Plant physiology 20070601

Title: Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

Journal: BMC bioinformatics 20070101

Title: [Overproduction of noncanonical amino acids by Escherichia coli cells].

Journal: Mikrobiologiia 20070101

Title: Intricate knots in proteins: Function and evolution.

Journal: PLoS computational biology 20060901

Title: Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans.

Journal: Oral microbiology and immunology 20060601

Title: Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

Journal: The Journal of biological chemistry 20050610

Title: Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

Journal: Organic & biomolecular chemistry 20050307

Title: Correlations between olfactory discrimination, olfactory receptor neuron responses and chemotopy of amino acids in fishes.

Journal: Chemical senses 20050101

Title: Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction.

Journal: Circulation 20041214

Title: Meteoritic C alpha-methylated alpha-amino acids and the homochirality of life: searching for a link.

Journal: Angewandte Chemie (International ed. in English) 20041210

Title: Presentation and detection of azide functionality in bacterial cell surface proteins.

Journal: Journal of the American Chemical Society 20040901

Title: The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.

Journal: The Biochemical journal 20040801

Title: Arginase pathway in human endothelial cells in pathophysiological conditions.

Journal: Journal of molecular and cellular cardiology 20040801

Title: High glucose augments arginase activity and nitric oxide production in the renal cortex.

Journal: Metabolism: clinical and experimental 20040701

Title: Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology-based modelling.

Journal: European journal of biochemistry 20031201

Title: Two new cyclosporin folds observed in the structures of the immunosuppressant cyclosporin G and the formyl peptide receptor antagonist cyclosporin H at ultra-high resolution.

Journal: Organic & biomolecular chemistry 20030507

Title: Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells.

Journal: British journal of cancer 20030210

Title: Arginine deprivation and tumour cell death: arginase and its inhibition.

Journal: Molecular and cellular biochemistry 20030201

Title: Consumption of L-arginine mediated by Entamoeba histolytica L-arginase (EhArg) inhibits amoebicidal activity and nitric oxide production by activated macrophages.

Journal: Parasite immunology 20030101

Title: Synthesis and biological evaluations of brain-targeted chemical delivery systems of [Nva2]-TRH.

Journal: The Journal of pharmacy and pharmacology 20020701

Title: Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.

Journal: Veterinary microbiology 20020501

Title: Sulfamide antifolates inhibiting thymidylate synthase: synthesis, enzyme inhibition and cytotoxicity.

Journal: Acta biochimica Polonica 20020101

Title: Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis.

Journal: European journal of biochemistry 20011101

Title: Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.

Journal: Journal of the American Chemical Society 20010822

Title: Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.

Journal: The Biochemical journal 20010315

Title: Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.

Journal: Cancer research 20010201

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SDS
Tags:6600-40-4 Molecular Formula|6600-40-4 MDL|6600-40-4 SMILES|6600-40-4 L-Norvaline
Catalog No.: AA003RA8
6600-40-4,MFCD00064421
6600-40-4 | L-Norvaline
Pack Size: 1g
Purity: 97%
in stock
$11.00 $8.00
Pack Size: 5g
Purity: 97%
in stock
$13.00 $9.00
Pack Size: 10g
Purity: 97%
in stock
$18.00 $13.00
Pack Size: 25g
Purity: 97%
in stock
$34.00 $24.00
Pack Size: 100g
Purity: 97%
in stock
$47.00 $33.00
Pack Size: 500g
Purity: 97%
in stock
$57.00 $40.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003RA8
Chemical Name: L-Norvaline
CAS Number: 6600-40-4
Molecular Formula: C5H11NO2
Molecular Weight: 117.1463
MDL Number: MFCD00064421
SMILES: CCC[C@@H](C(=O)O)N
Properties
Form: Solid  
MP: >300 °C(lit.)  
Refractive Index: 25 ° (C=10, 6mol/L HCl)  
Solubility: 48.7g/l  
Storage: Inert atmosphere;Room Temperature;  
Complexity: 82.5  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 8  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -2.1  
Upstream Synthesis Route
161633-98-3    2013-12-9    6600-40-4 

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#18,p.8126-8132

1821-02-9    2013-12-9    6600-40-4 

[1]JournaloftheAmericanChemicalSociety,1984,vol.106,#5,p.1490-1491

[2]JournaloftheAmericanChemicalSociety,1986,vol.108,#8,p.1969-1979

[3]OrganicLetters,2016,vol.18,#15,p.3658-3661

80174-42-1    2013-12-9    6600-40-4 

[1]JournalofOrganicChemistry,1994,vol.59,#25,p.7580-7581

[2]JournaloftheChineseChemicalSociety,1999,vol.46,#3,p.301-311

108341-16-8    2013-12-9    6600-40-4 

[1]OrganicLetters,2010,vol.12,#9,p.1916-1919

1116-19-4    56-41-7    338-69-2    2013-12-9    6600-40-4 

[1]Tetrahedron,1980,vol.36,#81,p.1089-1098

[2]Tetrahedron,1980,vol.36,#81,p.1089-1098

[3]Tetrahedron,1980,vol.36,#81,p.1089-1098

[4]Tetrahedron,1980,vol.36,#81,p.1089-1098

Downstream Synthesis Route
6600-40-4    41014-93-1 

[1]Fernández,Ariadna;Díaz,JoséLuis;García,Mónica;Rodríguez-Escrich,Sergi;Lorente,Adriana;Enrech,Raquel;Dordal,Albert;Portillo-Salido,Enrique;Porras,Mónica;Fernández,Begoña;Reinoso,RaquelF.;Vela,JoséMiguel;Almansa,Carmen[ACSMedicinalChemistryLetters,2021,vol.12,#11,p.1802-1809]

[2]Mori,Kenji;Takaishi,Hideo[Tetrahedron,1989,vol.45,#6,p.1639-1646]

[3]Winitzetal.[JournaloftheAmericanChemicalSociety,1956,vol.78,p.2423,2428]

[4]Baker;Meister[JournaloftheAmericanChemicalSociety,1951,vol.73,p.1336]

[5]Nakamura,Kaoru;Inoue,Kiyoko;Ushio,Kazutoshi;Oka,Shinzaburo;Ohno,Atsuyoshi[JournalofOrganicChemistry,1988,vol.53,#11,p.2589-2593]

[6]Raddatz,Peter;Minck,Klaus-Otto;Rippmann,Friedrich;Schmitges,Claus-Jochen[JournalofMedicinalChemistry,1994,vol.37,#4,p.486-497]

6600-40-4    21691-44-1 

[1]JournalofBiochemistry,1959,vol.46,p.19,21

67-56-1    6600-40-4    56558-30-6 

[1]AngewandteChemie,1992,vol.104,p.97-99

[2]Synthesis,2010,p.2915-2921

[3]Patent:WO2013/136265,2013,A1.Locationinpatent:Page/Pagecolumn21-22

[4]Patent:WO2004/33434,2004,A1.Locationinpatent:Page34

[5]Heterocycles,1998,vol.47,p.765-780

[6]Phytochemistry,1988,vol.27,p.77-84

[7]EuropeanJournalofOrganicChemistry,2002,p.3763-3767

[8]Patent:WO2006/44775,2006,A2.Locationinpatent:Page/Pagecolumn36

[9]JournalofMedicinalChemistry,2017,vol.60,p.5889-5908

760-78-1    2013-12-9    6600-40-4 

[1]JournaloftheAmericanChemicalSociety,1980,vol.102,p.5115-5117

[2]CatalysisLetters,2018,vol.148,p.3678-3684

6600-40-4    58632-95-4    53308-95-5 

[1]Tetrahedron,1991,vol.47,p.5453-5462

Literature fold

Title: Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps.

Journal: The Journal of biological chemistry20120720

Title: Glutamine and glutathione at ICU admission in relation to outcome.

Journal: Clinical science (London, England : 1979)20120601

Title: Metabolome analysis of gram-positive bacteria such as Staphylococcus aureus by GC-MS and LC-MS.

Journal: Methods in molecular biology (Clifton, N.J.)20120101

Title: Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production.

Journal: Vascular pharmacology20120101

Title: New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.

Journal: PloS one20120101

Title: Combination of valproate and paroxetine in mice exposed to picrotoxin.

Journal: International journal of nanomedicine20120101

Title: Jadomycins derived from the assimilation and incorporation of norvaline and norleucine.

Journal: Journal of natural products20111128

Title: An evolutionary strategy for isobutanol production strain development in Escherichia coli.

Journal: Metabolic engineering20111101

Title: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.

Journal: The FEBS journal20110901

Title: Understanding the molecular dynamics associated with polymorphic transitions of DL-norvaline with solid-state NMR methods.

Journal: The journal of physical chemistry. B20110331

Title: Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction.

Journal: The journal of physical chemistry. B20110317

Title: A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum.

Journal: BMC microbiology20110101

Title: Arginase inhibitor in the pharmacological correction of endothelial dysfunction.

Journal: International journal of hypertension20110101

Title: Establishment of reference range of plasma amino acids for younger Chinese children by reverse phase HPLC.

Journal: Journal of pediatric endocrinology & metabolism : JPEM20110101

Title: Ligand-induced changes in the conformational stability and flexibility of glutamate dehydrogenase and their role in catalysis and regulation.

Journal: Protein science : a publication of the Protein Society20101001

Title: RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis.

Journal: Plant molecular biology20100901

Title: Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice.

Journal: Heart and vessels20100501

Title: A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.

Journal: Journal of medicinal chemistry20100211

Title: Specificities of olfactory receptor neuron responses to amino acids in the black bullhead catfish (Ameiurus melas).

Journal: Pflugers Archiv : European journal of physiology20100201

Title: Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy.

Journal: The journal of physical chemistry. B20100128

Title: Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

Journal: Toxicology and applied pharmacology20090901

Title: Kinetic and thermodynamic control in the stereoselective formation of trans- and cis-2-ferrocenyl-3-pivaloyl-4-alkyl-1,3-oxazolidin-5-ones.

Journal: Organic & biomolecular chemistry20090207

Title: Cyclosporins from Mycelium sterilae MS 2929.

Journal: Journal of natural products20090101

Title: Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline.

Journal: BMC cardiovascular disorders20090101

Title: A 3(10)-helical pentapeptide in water: interplay of alpha,alpha-disubstituted amino acids and the central residue on structure formation.

Journal: Biopolymers20090101

Title: The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.

Journal: Journal of molecular biology20080125

Title: Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.

Journal: BMC biochemistry20080101

Title: Enzymatic evidence for the key role of arginine in nitrogen translocation by arbuscular mycorrhizal fungi.

Journal: Plant physiology20070601

Title: Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

Journal: BMC bioinformatics20070101

Title: [Overproduction of noncanonical amino acids by Escherichia coli cells].

Journal: Mikrobiologiia20070101

Title: Intricate knots in proteins: Function and evolution.

Journal: PLoS computational biology20060901

Title: Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans.

Journal: Oral microbiology and immunology20060601

Title: Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

Journal: The Journal of biological chemistry20050610

Title: Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

Journal: Organic & biomolecular chemistry20050307

Title: Correlations between olfactory discrimination, olfactory receptor neuron responses and chemotopy of amino acids in fishes.

Journal: Chemical senses20050101

Title: Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction.

Journal: Circulation20041214

Title: Meteoritic C alpha-methylated alpha-amino acids and the homochirality of life: searching for a link.

Journal: Angewandte Chemie (International ed. in English)20041210

Title: Presentation and detection of azide functionality in bacterial cell surface proteins.

Journal: Journal of the American Chemical Society20040901

Title: The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.

Journal: The Biochemical journal20040801

Title: Arginase pathway in human endothelial cells in pathophysiological conditions.

Journal: Journal of molecular and cellular cardiology20040801

Title: High glucose augments arginase activity and nitric oxide production in the renal cortex.

Journal: Metabolism: clinical and experimental20040701

Title: Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology-based modelling.

Journal: European journal of biochemistry20031201

Title: Two new cyclosporin folds observed in the structures of the immunosuppressant cyclosporin G and the formyl peptide receptor antagonist cyclosporin H at ultra-high resolution.

Journal: Organic & biomolecular chemistry20030507

Title: Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells.

Journal: British journal of cancer20030210

Title: Arginine deprivation and tumour cell death: arginase and its inhibition.

Journal: Molecular and cellular biochemistry20030201

Title: Consumption of L-arginine mediated by Entamoeba histolytica L-arginase (EhArg) inhibits amoebicidal activity and nitric oxide production by activated macrophages.

Journal: Parasite immunology20030101

Title: Synthesis and biological evaluations of brain-targeted chemical delivery systems of [Nva2]-TRH.

Journal: The Journal of pharmacy and pharmacology20020701

Title: Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.

Journal: Veterinary microbiology20020501

Title: Sulfamide antifolates inhibiting thymidylate synthase: synthesis, enzyme inhibition and cytotoxicity.

Journal: Acta biochimica Polonica20020101

Title: Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis.

Journal: European journal of biochemistry20011101

Title: Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.

Journal: Journal of the American Chemical Society20010822

Title: Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.

Journal: The Biochemical journal20010315

Title: Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.

Journal: Cancer research20010201

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