Title: Total synthesis of 7',8'-dihydroaigialospirol.
Journal: Organic letters20121005
Title: Design and synthesis of marine fungal phthalide derivatives as PPAR-γ agonists.
Journal: Bioorganic & medicinal chemistry20120815
Title: C(Ar)-H···O hydrogen bonds in substituted isobenzofuranone derivatives: geometric, topological, and NMR characterization.
Journal: The journal of physical chemistry. A20120726
Title: Metabolic conversion from co-existing ingredient leading to significant systemic exposure of Z-butylidenephthalide, a minor ingredient in Chuanxiong Rhizoma in rats.
Journal: Current drug metabolism20120601
Title: Phthalide and isocoumarin derivatives produced by an Acremonium sp. isolated from a mangrove Rhizophora apiculata.
Journal: Journal of natural products20120525
Title: Direct asymmetric Mannich reaction of phthalides: facile access to chiral substituted isoquinolines and isoquinolinones.
Journal: Chemical communications (Cambridge, England)20120516
Title: CN-assisted oxidative cyclization of cyano cinnamates and styrene derivatives: a facile entry to 3-substituted chiral phthalides.
Journal: Organic & biomolecular chemistry20120514
Title: Nucleophile- or light-induced synthesis of 3-substituted phthalides from 2-formylarylketones.
Journal: Organic letters20120504
Title: Simultaneous determination of nine related substances in p-phthalic acid residue by RP-HPLC.
Journal: Journal of chromatographic science20120501
Title: Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino-α-noscapine from natural α-noscapine.
Journal: Bioorganic & medicinal chemistry letters20120415
Title: Stereoselective synthesis of hydroxy stilbenoids and styrenes by atom-efficient olefination with thiophthalides.
Journal: Organic & biomolecular chemistry20120414
Title: A novel antioxidant isobenzofuranone derivative from fungus Cephalosporium sp.AL031.
Journal: Molecules (Basel, Switzerland)20120405
Title: Highly stereoselective chemoenzymatic synthesis of the 3H-isobenzofuran skeleton. Access to enantiopure 3-methylphthalides.
Journal: Organic letters20120316
Title: Anti-inflammatory effects of (Z)-ligustilide through suppression of mitogen-activated protein kinases and nuclear factor-κB activation pathways.
Journal: Archives of pharmacal research20120301
Title: Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones.
Journal: Bioorganic & medicinal chemistry20120201
Title: Two phthalide dimers from the radix of Angelica sinensis.
Journal: Natural product research20120101
Title: Ligustilide: a novel TRPA1 modulator.
Journal: Pflugers Archiv : European journal of physiology20111201
Title: Two new compounds from an endophytic fungus Pestalotiopsis heterocornis.
Journal: Journal of Asian natural products research20111201
Title: The atmospheric photolysis of o-tolualdehyde.
Journal: Environmental science & technology20111115
Title: Phthalide derivatives with antifungal activities against the plant pathogens isolated from the liquid culture of Pestalotiopsis photiniae.
Journal: The Journal of antibiotics20111101
Title: Ligusticum chuanxiong Hort: a review of chemistry and pharmacology.
Journal: Pharmaceutical biology20111101
Title: Synthesis of biarylketones and phthalides from organoboronic acids and aldehydes catalyzed by cobalt complexes.
Journal: Chemical communications (Cambridge, England)20111007
Title: Ruthenium-catalyzed oxidative C-H bond alkenylations in water: expedient synthesis of annulated lactones.
Journal: Organic letters20110819
Title: Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci.
Journal: Journal of agricultural and food chemistry20110810
Title: Phthalides and other constituents from Ligusticum porteri; sedative and spasmolytic activities of some natural products and derivatives.
Journal: Natural product research20110801
Title: Design and synthesis of protein kinase Cα activators based on 'out of pocket' interactions.
Journal: Bioorganic & medicinal chemistry letters20110615
Title: Benzannulation for the regiodefined synthesis of 2-alkyl/aryl-1-naphthols: total synthesis of arnottin I.
Journal: The Journal of organic chemistry20110506
Title: Chemical composition of the essential oil from kelussia odoratissima Mozaff. and the evaluation of its sedative and anxiolytic effects in mice.
Journal: Clinics (Sao Paulo, Brazil)20110501
Title: Correlative analysis of metabolite profiling of Danggui Buxue Tang in rat biological fluids by rapid resolution LC-TOF/MS.
Journal: Journal of pharmaceutical and biomedical analysis20110428
Title: Metabolic profiling of GuanXin II prescription based on metabolic fingerprinting and chemical analysis.
Journal: Journal of pharmaceutical and biomedical analysis20110325
Title: Cytotoxic bibenzyls, and germacrane- and pinguisane-type sesquiterpenoids from Indonesian, Tahitian and Japanese liverworts.
Journal: Natural product communications20110301
Title: Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.
Journal: Journal of natural products20110128
Title: The use of endophytes to obtain bioactive compounds and their application in biotransformation process.
Journal: Biotechnology research international20110101
Title: Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS.
Journal: Phytochemical analysis : PCA20110101
Title: Antimicrobial activities of hexane extract and decussatin from stembark extract of Ficus congensis.
Journal: International journal of molecular sciences20110101
Title: Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway.
Journal: Frontiers in microbiology20110101
Title: Bioactivities of major constituents isolated from Angelica sinensis (Danggui).
Journal: Chinese medicine20110101
Title: Polyphasic analysis of intraspecific diversity in Epicoccum nigrum warrants reclassification into separate species.
Journal: PloS one20110101
Title: Antibacterial activity of new dibenzoxepinone oximes with fluorine and trifluoromethyl group substituents.
Journal: International journal of molecular sciences20110101
Title: Synthesis and Antimicrobial Evaluation of Dibenzo[b,e]oxepin-11(6H)-one O-Benzoyloxime Derivatives.
Journal: Scientia pharmaceutica20110101
Title: Marilones A-C, phthalides from the sponge-derived fungus Stachylidium sp.
Journal: Beilstein journal of organic chemistry20110101
Title: A practical total synthesis of (+)-spirolaxine methyl ether.
Journal: The Journal of organic chemistry20101203
Title: New isocourmarin and phthalide derivatives from the rhizomes of Matteuccia orientalis.
Journal: Chemical & pharmaceutical bulletin20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters20101101
Title: Palladium-catalyzed cascade aryl addition/intramolecular lactonization of phthalaldehyde to access 3-aryl- and alkenylphthalides.
Journal: The Journal of organic chemistry20100903
Title: Synthesis of demethylated nidulol via an intramolecular Michael reaction.
Journal: Natural product research20100801
Title: 3-Acetyl-benzoic acid.
Journal: Acta crystallographica. Section E, Structure reports online20100701
Title: Rhodium-catalyzed cascade reaction: aryl addition/intramolecular esterification to access 3-aryl and 3-alkenyl phthalides.
Journal: Angewandte Chemie (International ed. in English)20100510
Title: Transition metal-catalyzed addition reactions of arylboronic acids with alkyl 2-formylbenzoates: efficient access to chiral 3-substituted phthalides.
Journal: Chemical communications (Cambridge, England)20100507
Title: Pesticide residues in coastal waters affected by rice paddy effluents temporarily stored in a wastewater reservoir in southern Japan.
Journal: Archives of environmental contamination and toxicology20100201
Title: Synthesis of chiral 3-substituted phthalides by a sequential organocatalytic enantioselective aldol-lactonization reaction. Three-step synthesis of (S)-(-)-3-butylphthalide.
Journal: The Journal of organic chemistry20100115
Title: Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong.
Journal: Molecules (Basel, Switzerland)20100115
Title: Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.
Journal: Biological & pharmaceutical bulletin20100101
Title: Efficient synthesis of 3-arylphthalides using palladium-catalyzed arylation of aldehydes with organoboronic acids.
Journal: The Journal of organic chemistry20091204
Title: Evaluation of the in vivo antimalarial activity of ethanolic leaf and stembark extracts of Anthocleista djalonensis.
Journal: Indian journal of pharmacology20091201
Title: Phthalides by rhodium-catalyzed ketone hydroacylation.
Journal: Journal of the American Chemical Society20091104
Title: Catalytic enantioselective synthesis of chiral phthalides by efficient reductive cyclization of 2-acylarylcarboxylates under aqueous transfer hydrogenation conditions.
Journal: Organic letters20091015
Title: 3,3'-Oxybi[isobenzofuran-1(3H)-one].
Journal: Acta crystallographica. Section E, Structure reports online20091001
Title: Two new compounds from the roots of Ligusticum chuanxiong.
Journal: Journal of Asian natural products research20090901
Title: A novel compound from celery seed with a bactericidal effect against Helicobacter pylori.
Journal: The Journal of pharmacy and pharmacology20090801
Title: Identification of metabolites of Danggui Buxue Tang in rat urine by liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20090701
Title: Biomimetic studies towards the cardinalins: synthesis of (+)-ventiloquinone L and an unusual dimerisation.
Journal: Organic & biomolecular chemistry20090621
Title: Daily variation of pesticides in surface water of a small river flowing through paddy field area.
Journal: Bulletin of environmental contamination and toxicology20090601
Title: Preparative isolation and purification of isobenzofuranone derivatives and saponins from seeds of Nigella glandulifera Freyn by high-speed counter-current chromatography combined with gel filtration.
Journal: Journal of chromatography. A20090508
Title: 2-(3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phthalazin-1(2H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20090501
Title: Occurence and bioactivities of funicone-related compounds.
Journal: International journal of molecular sciences20090401
Title: New phthalide glycosides from Helichrysum arenarium (L.) Moench.
Journal: Journal of Asian natural products research20090101
Title: Simultaneous determination of phenolic acids and phthalide compounds by liquid chromatography for quality assessment of Rhizoma cnidii.
Journal: Journal of AOAC International20090101
Title: New antitumour fungal metabolites from Alternaria porri.
Journal: Natural product research20090101
Title: Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes.
Journal: Parasitology research20081201
Title: [Analysis of principal composition of ethyl acetate part in Huangqi Danggui decoction by HPLC-ESI-TOF-MS].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20081101
Title: Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells.
Journal: Journal of ethnopharmacology20081030
Title: Decrease of 4,5,6,7-tetrachlorophthalide in paddy field soil after aerial application.
Journal: Bulletin of environmental contamination and toxicology20081001
Title: Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.
Journal: Journal of natural products20081001
Title: Dynamic nature of the ligustilide complex.
Journal: Journal of natural products20080901
Title: 3-(5,6,7,8-Tetra-hydro-2-naphth-yl)iso-benzofuran-1(3H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20080901
Title: Rapid and sensitive screening and characterization of phenolic acids, phthalides, saponins and isoflavonoids in Danggui Buxue Tang by rapid resolution liquid chromatography/diode-array detection coupled with time-of-flight mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20080801
Title: Anti-Helicobacter pylori activity of derivatives of the phthalide-containing antibacterial agents spirolaxine methyl ether, CJ-12,954, CJ-13,013, CJ-13,102, CJ-13,104, CJ-13,108 and CJ-13,015.
Journal: Bioorganic & medicinal chemistry20080601
Title: Variation of 4,5,6,7-tetrachlorophthalide in water after aerial application to rice cultivation area.
Journal: Bulletin of environmental contamination and toxicology20080501
Title: 3-(4-Methyl-piperazin-1-yl)isobenzofuran-1(3H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20080501
Title: 3-(2-Hydr-oxy-5-methyl-anilino)isobenzo-furan-1(3H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20080501
Title: High-performance liquid chromatographic assay with ultraviolet spectrometric detection for the evaluation of inhibitors of phosphatidylinositol-specific phospholipase C.
Journal: Analytical biochemistry20080415
Title: 2-(3-Oxo-1,3-dihydro-isobenzofuran-1-ylamino)benzoic acid.
Journal: Acta crystallographica. Section E, Structure reports online20080401
Title: 3-(2-Chloro-anilino)isobenzofuran-1(3H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20080401
Title: 3-(2,4-Dichloro-anilino)iso-benzo-furan-1(3H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20080401
Title: [GC-MS analysis of essential oil from rhizomes of Ligusticum chuanxiong cultivated in GAP base for Chinese medicinal materials of China].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080201
Title: Flavor enhancement of chicken broth from boiled celery constituents.
Journal: Journal of agricultural and food chemistry20080123
Title: Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats.
Journal: Pharmacology, biochemistry, and behavior20080101
Title: Diketopiperazines and phthalides from a marine derived fungus of the order pleosporales.
Journal: Planta medica20080101
Title: Chemical markers for the quality control of herbal medicines: an overview.
Journal: Chinese medicine20080101
Title: Reductive dechlorination of chloroethenes by Dehalococcoides-containing cultures enriched from a polychlorinated-dioxin-contaminated microcosm.
Journal: The ISME journal20071001
Title: Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone.
Journal: Bioorganic & medicinal chemistry letters20070915
Title: Importance of interaction between C1 domain and lipids in protein kinase C alpha activation: hydrophobic side chain direction in isobenzofuranone ligands controls enzyme activation level.
Journal: ChemMedChem20070701
Title: Direct access to 1,4-dihydroxyanthraquinones: the Hauser annulation reexamined with p-quinones.
Journal: The Journal of organic chemistry20070622
Title: Studies on antiproliferative effects of phthalides from Ligusticum chuanxiong in hepatic stellate cells.
Journal: Planta medica20070601
Title: The structural diversity of phthalides from the Apiaceae.
Journal: Journal of natural products20070501
Title: Comparative analysis of Ligusticum chuanxiong and related umbelliferous medicinal plants by high performance liquid chromatography-electrospray ionization mass spectrometry.
Journal: Planta medica20070401
Title: Rhodium-catalyzed asymmetric one-pot transesterification and [2 + 2 + 2] cycloaddition leading to enantioenriched 3,3-disubstituted phthalides.
Journal: Organic letters20070329
Title: Highly efficient cyclization of o-iodobenzoates with aldehydes catalyzed by cobalt bidentate phosphine complexes: a novel entry to chiral phthalides.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20070101
Title: An alkyne strategy for the asymmetric synthesis of natural products: application to (+)-spirolaxine methyl ether.
Journal: Angewandte Chemie (International ed. in English)20070101
Title: Absolute configuration of sporotricale and structure of 6-hydroxysporotricale.
Journal: Journal of natural products20061201
Title: Regiocontrolled intramolecular cyclizations of carboxylic acids to carbon-carbon triple bonds promoted by acid or base catalyst.
Journal: Organic letters20061123
Title: The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo.
Journal: Journal of neurochemistry20061101
Title: [High performance liquid chromatography-mass spectrometry analysis of radix Angelica sciensis].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20061101
Title: Runoff of aerially applied phthalide from paddy fields.
Journal: Bulletin of environmental contamination and toxicology20061001
Title: Kinetics and products of photolysis and reaction with OH radicals of a series of aromatic carbonyl compounds.
Journal: Environmental science & technology20060901
Title: Synthesis of (+)-spirolaxine methyl ether.
Journal: The Journal of organic chemistry20060804
Title: Uptake and UV-photooxidation of gas-phase PAHs on the surface of atmospheric water films. 1. Naphthalene.
Journal: The journal of physical chemistry. A20060727
Title: Antiproliferative effect of Baylis-Hillman adducts and a new phthalide derivative on human tumor cell lines.
Journal: European journal of medicinal chemistry20060601
Title: Two new phthalides from Ligusticum chuanxiong.
Journal: Planta medica20060601
Title: Determination of volatile flavor components in danggui cultivars by solvent free injection and hydrodistillation followed by gas chromatographic-mass spectrometric analysis.
Journal: Journal of chromatography. A20060526
Title: Synthesis of benz[d]indeno[1,2-b]pyran-5,11-diones: versatile intermediates for the design and synthesis of topoisomerase I inhibitors.
Journal: Bioorganic & medicinal chemistry letters20060401
Title: Potent odorants characterize the aroma quality of leaves and stalks in raw and boiled celery.
Journal: Bioscience, biotechnology, and biochemistry20060401
Title: Total synthesis and biological evaluation of 22-hydroxyacuminatine.
Journal: Journal of medicinal chemistry20060223
Title: Simultaneous qualitative and quantitative analyses of the major constituents in the rhizome of Ligusticum Chuanxiong using HPLC-DAD-MS.
Journal: Chemical & pharmaceutical bulletin20060201
Title: Sulfated mesoporous alumina: a highly effective solid strong base catalyst for the Tishchenko reaction in supercritical carbon dioxide.
Journal: The journal of physical chemistry. B20060126
Title: Total syntheses of oxygenated brazanquinones via regioselective homologous anionic Fries rearrangement of benzylic O-carbamates.
Journal: Beilstein journal of organic chemistry20060101
Title: GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels.
Journal: Phytochemical analysis : PCA20060101
Title: A brief and convergent synthetic route to defucogilvocarcin M chromophore: the formal synthesis of WS-5995 A and C.
Journal: The Journal of organic chemistry20051028
Title: Phthalide Lactones from Ligusticum chuanxiong inhibit lipopolysaccharide-induced TNF-alpha production and TNF-alpha-mediated NF-kappaB Activation.
Journal: Planta medica20050901
Title: Anxiolytic effects of benzalphthalides.
Journal: Bioorganic & medicinal chemistry letters20050801
Title: Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster.
Journal: Journal of agricultural and food chemistry20050713
Title: Synthesis of enantiopure phthalides including 3-butylphthalide, a fragrance component of celery oil, and determination of their absolute configurations.
Journal: Chirality20050505
Title: [Protective effect of ligusticum chuanxiong phthalides on focai cerebral ischemia in rats and its related mechanism of action].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050301
Title: Enantiomerical excess determination, purification and biological evaluation of (3S) and (3R) alpha,beta-butenolide analogues of isobenzofuranone.
Journal: Bioorganic & medicinal chemistry letters20050201
Title: [New dimeric phthalide derivative from Angelica sinensis].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20050201
Title: HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong.
Journal: Molecular diversity20050101
Title: Efficient synthesis of isobenzofuran-1(3H)-ones (phthalides) and selected biological evaluations.
Journal: Arzneimittel-Forschung20050101
Title: A phthalide with in vitro growth inhibitory activity from an oidiodendron strain.
Journal: Journal of natural products20041201
Title: Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster.
Journal: Journal of agricultural and food chemistry20040714
Title: Synthesis of phthalide derivatives using nickel-catalyzed cyclization of o-haloesters with aldehydes.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20040621
Title: Design, synthesis, and structure-activity relationship of new isobenzofuranone ligands of protein kinase C.
Journal: Bioorganic & medicinal chemistry letters20040607
Title: Evaluation of series of isobenzofuranone dimers as PKCalpha ligands: implication for the distance between the two ligand binding sites.
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Title: Polar constituents of celery seed.
Journal: Phytochemistry20031101
Title: A new regiospecific preparation of xanthones.
Journal: Organic letters20031002
Title: Synthesis and absolute configuration of (-)-3-butyl-7-hydroxyphthalide, a cytotoxic metabolite of Penicillium vulpinum.
Journal: Bioscience, biotechnology, and biochemistry20031001
Title: Characterization of phthalides in Ligusticum chuanxiong by liquid chromatographic-atmospheric pressure chemical ionization-mass spectrometry.
Journal: Journal of chromatographic science20030901
Title: A new antioxidant isobenzofuranone derivative from the algicolous marine fungus Epicoccum sp.
Journal: Planta medica20030901
Title: Total synthesis of (+/-)-O-methyl PD 116740.
Journal: Organic letters20020627
Title: Isopestacin, an isobenzofuranone from Pestalotiopsis microspora, possessing antifungal and antioxidant activities.
Journal: Phytochemistry20020501
Title: Application of microgels as polymer supports for organic synthesis: preparation of a small phthalide library, a scavenger, and a borohydride reagent.
Journal: Journal of combinatorial chemistry20020101
Title: Efficient heterogeneous catalytic intramolecular Tishchenko reaction of o-phthalaldehyde to phthalide with alkaline earth oxides.
Journal: Chemical communications (Cambridge, England)20011207
Title: A new alternative synthesis of 5-cyanophthalide, a versatile intermediate in the preparation of the antidepressant drug citalopram.
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Title: Characterization of an unknown component in Noscapine using liquid chromatography-mass spectrometry and proton nuclear magnetic resonance spectroscopy.
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Title: Structures of trihydroxynaphthalene reductase-fungicide complexes: implications for structure-based design and catalysis.
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Title: Solid-phase directed ortho-lithiation and the preparation of a phthalide library.
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Title: Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines.
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