Home Other Building Blocks 94055-76-2
94055-76-2,MFCD00867604
Catalog No.:AA003UED

94055-76-2 | Suplatast tosilate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$12.00   $8.00
- +
10mg
98%
in stock  
$22.00   $15.00
- +
25mg
98%(HPLC)
in stock  
$37.00   $26.00
- +
50mg
98%
in stock  
$48.00   $34.00
- +
100mg
>98.0%(HPLC)(N)
in stock  
$59.00   $41.00
- +
1g
>98.0%(HPLC)(N)
in stock  
$347.00   $243.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003UED
Chemical Name:
Suplatast tosilate
CAS Number:
94055-76-2
Molecular Formula:
C23H33NO7S2
Molecular Weight:
499.6406
MDL Number:
MFCD00867604
SMILES:
Cc1ccc(cc1)S(=O)(=O)[O-].CCOCC(COc1ccc(cc1)NC(=O)CC[S+](C)C)O
Properties
Properties
 
Form:
Solid  
MP:
84-87 °C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
500  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
Undefined Atom Stereocenter Count:
1  

Literature

Title: [Idiopathic hypereosinophilic syndrome in a child with fever and hepatomegaly].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20120101

Title: Long-term monotherapy with suplatast tosilate in patients with mild atopic asthma: a pilot comparison with low-dose inhaled fluticasone.

Journal: Asian Pacific journal of allergy and immunology 20110601

Title: Angiolymphoid hyperplasia with eosinophilia on the leg successfully treated with T-helper cell 2 cytokine inhibitor suplatast tosilate.

Journal: The Journal of dermatology 20110301

Title: Kimura's disease treated with suplatast tosilate and loratadine.

Journal: European journal of dermatology : EJD 20110101

Title: Eosinophilic gastroenteritis associated with giant folds.

Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 20101001

Title: Early intervention with suplatast tosilate for prophylaxis of pediatric atopic asthma: a pilot study.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20090801

Title: Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090801

Title: New thinking in the development of novel derivatization reagents for liquid chromatography-mass spectrometric detection.

Journal: Biomedical chromatography : BMC 20090101

Title: Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: Th2 cytokine inhibitor suplatast tosilate inhibits antigen-induced mucus hypersecretion in the nasal epithelium of sensitized rats.

Journal: The Annals of otology, rhinology, and laryngology 20090101

Title: A case of eosinophilic pneumonia successfully treated with suplatast tosilate alone.

Journal: International archives of allergy and immunology 20090101

Title: Interaction of suplatast tosilate (IPD) with chloride channels in human blood eosinophils: a potential mechanism underlying its anti-allergic and anti-asthmatic effects.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080201

Title: Pemphigoid nodularis associated with psoriatic erythroderma: successful treatment with suplatast tosilate.

Journal: The British journal of dermatology 20080201

Title: Effect of an orally active Th2 cytokine inhibitor, suplatast on 'atopic cough' tosilate.

Journal: Arzneimittel-Forschung 20080101

Title: Liquid chromatography/electrospray ionization mass spectrometry method for the determination of the active metabolite M-1 of suplatast tosilate in human plasma.

Journal: Biomedical chromatography : BMC 20071201

Title: Beneficial effects of suplatast tosilate (IPD-1151T) in a rat cystitis model induced by intravesical hydrochloric acid.

Journal: BJU international 20071001

Title: Suplatast/tacrolimus combination therapy for refractory facial erythema in adult patients with atopic dermatitis: a meta-analysis study.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20070901

Title: Inhibitory effects of suplatast tosilate on the differentiation and function of monocyte-derived dendritic cells from patients with asthma.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070701

Title: Intravesical suplatast tosilate (IPD-1151T) inhibits experimental bladder inflammation.

Journal: The Journal of urology 20070301

Title: Topical suplatast tosilate (IPD) ameliorates Th2 cytokine-mediated dermatitis in caspase-1 transgenic mice by downregulating interleukin-4 and interleukin-5.

Journal: The British journal of dermatology 20060701

Title: Suplatast tosilate alters DC1/DC2 balance in peripheral blood in bronchial asthma.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20050901

Title: [Case of interstitial cystitis accompanied by food allergy].

Journal: Arerugi = [Allergy] 20050701

Title: Inhibition of theophylline metabolism by suplatast and its metabolites in rats.

Journal: Biological & pharmaceutical bulletin 20050601

Title: Suplatast tosilate dimethylsulfonium treatment for steroid-dependent nephrotic syndrome.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20050401

Title: CD28 and secretory immunoglobulin A-dependent activation of eosinophils: inhibition of mediator release by the anti-allergic drug, suplatast tosilate.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

Title: [Hypereosinophilic syndrome complicated by disseminated intravascular coagulation (DIC), deep venous thrombosis and pulmonary embolism].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040210

Title: Th2 cytokine inhibition and cough in asthmatic and bronchitic patients.

Journal: Annals of medicine 20040101

Title: [The effect of suplatast tosilate on the patients with atopic dermatitis--relationship between clinical symptoms and immunological parameters].

Journal: Arerugi = [Allergy] 20031101

Title: Suplatast tosilate inhibits eosinophil production and recruitment into the skin in murine contact sensitivity.

Journal: Clinical immunology (Orlando, Fla.) 20030901

Title: Breath malodor in an asthmatic patient caused by side-effects of medication: a case report and review of the literature.

Journal: Oral diseases 20030901

Title: Effects of suplatast tosilate on allergic eosinophilic airway inflammation in patients with mild asthma.

Journal: The Journal of allergy and clinical immunology 20030501

Title: Effect of suplatast tosilate, an antiallergic selective Th2 cytokine inhibitor, on acute eosinophilic myocarditis: a case report.

Journal: Heart and vessels 20030501

Title: [A case of Sjögren syndrome accompanied by interstitial cystitis and interstitial pneumonia improved by suplatast tosilate and prednisolone].

Journal: Arerugi = [Allergy] 20030401

Title: [Combined drug therapy for patients with intractable paranasal sinusitis complicating allergic rhinitis].

Journal: The Japanese journal of antibiotics 20030401

Title: Add-on effects of suplatast tosilate in bronchial asthma patients treated with inhaled corticosteroids.

Journal: Lung 20030101

Title: Suplatast tosilate inhibits thymus- and activation-regulated chemokine production by antigen-specific human Th2 cells.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021201

Title: Improvement of alanine aminotransferase by administration of suplatast tosilate plus ursodeoxycholic acid in patients with resistance to ursodeoxycholic acid monotherapy on hepatitis C virus-related chronic liver disease.

Journal: Internal medicine (Tokyo, Japan) 20021001

Title: Effects of suplatast tosilate on cytokine profile of bronchoalveolar cells in allergic inflammation of the lung.

Journal: Respirology (Carlton, Vic.) 20020901

Title: Effect of suplatast tosilate, a Th2 cytokine inhibitor, on cough variant asthma.

Journal: European journal of clinical pharmacology 20020601

Title: Azelastine and suplatast shorten the distribution half-life of IgE in rats.

Journal: Mediators of inflammation 20020201

Title: Understanding chronic pelvic pain syndrome.

Journal: Current opinion in urology 20020101

Title: Suppression of the Th2 pathway by suplatast tosilate in patients with perennial nasal allergies.

Journal: American journal of rhinology 20020101

Title: Effects of suplatast tosilate, a new type of anti-allergic agent, on airway cough hypersensitivity induced by airway allergy in guinea-pigs.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20011201

Title: Modification of eosinophil function by suplatast tosilate (IPD), a novel anti-allergic drug.

Journal: International immunopharmacology 20011101

Title: Effects of suplatast tosilate on airway inflammation and airway hyperresponsiveness.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20010601

Title: [Cytokine production by peripheral blood mononuclear cells in bronchial asthma treated with suplatast tosilate].

Journal: Arerugi = [Allergy] 20010601

Title: Yanagihara Y, et, al. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2). Regulation of human IgE response. Jpn J Pharmacol. 1993 Jan;61(1):31-9.

Title: Zhao GD, et, al. Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness. Int Arch Allergy Immunol. 2000 Feb;121(2):116-22.

Title: Kurokawa M, et, al. Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 2001 Dec;10(6):333-7.

Title: Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N.Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 94055-76-2
Tags:94055-76-2 Molecular Formula|94055-76-2 MDL|94055-76-2 SMILES|94055-76-2 Suplatast tosilate